[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"ramadan-fasting\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:ramadan-fasting":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":17,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":32,"overallStatus":41,"whyStopped":4,"lastUpdateSubmitDate":42,"lastUpdatePostDateStruct":43,"startDateStruct":46,"completionDateStruct":48,"leadSponsor":50,"locationsCount":5},"100621192","risks-of-ramadan-fasting-in-patients-with-primary-adrenal-insufficiency-treated-with-prednisolone-100621192",false,"NCT07367425","Risks of Ramadan Fasting in Patients With Primary Adrenal Insufficiency Treated With Prednisolone.","Inclusion Criteria:\n\n* subjects with primary adrenal insufficiency known for at least one year, treated with a glucocorticoid and a mineralocorticoid, who wish to fast during Ramadan 2026.\n\nExclusion Criteria:\n\n* presence of diabetes, renal, hepatic, cardiac, or respiratory insufficiency; use of hypoglycemic agents (sulfonylureas), diuretics, use of any glucocorticoid other than the prescribed replacement therapy; poor disease control (asthenia, malaise, hyperpigmentation, discontinuation of treatment, etc.); pregnancy; breastfeeding; menstruation.","ALL","20 Years","70 Years",{"count":19,"type":20},35,"ESTIMATED","INTERVENTIONAL",[23],"NA","In primary adrenal insufficiency (PAI), there is a risk of hypoglycemia and dehydration. These risks seem to be increased during intermittent fasting. A previous study in patients with PAI treated with hydrocortisone at a dose of 20 mg\u002Fday showed that the prevalence of hypoglycemia was as high outside (63%) as during Ramadan fasting (71%), and that there was no risk of dehydration. We propose to evaluate the risk of complications during and outside of Ramadan fasting through a prospective study with subjects taken as their own controls, in 35 patients with PAI treated with prednisolone at a dose of 5 mg\u002Fday. Patients will undergo an interview, physical examination, blood sampling, and continuous glucose monitoring (CGM) during two weeks of fasting and two weeks of non-fasting.",[26,27,28,29,30,31],"Primary Adrenal Insufficiency","Ramadan Fasting","Prednisolone","Continuous Glucose Monitoring","Hypoglycemia Non-Diabetic","Dehydration",[33,34,35,36,37,38,39,40],"primary adrenal insufficiency","Ramadan fasting","continuous glucose monitoring","hypoglycemia","dehydration","glucocorticoid replacement therapy","prednisolone","hypotension","NOT_YET_RECRUITING","2026-01-16",{"date":44,"type":45},"2026-01-26","ACTUAL",{"date":47,"type":20},"2026-01-22",{"date":49,"type":20},"2026-03-30",{"name":51,"class":52},"Hopital La Rabta","OTHER"]