[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"reconstructive-surgery\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:reconstructive-surgery":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,4,0,[8,43,65,89],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":14,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":29,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":31,"lastUpdatePostDateStruct":32,"startDateStruct":35,"completionDateStruct":37,"leadSponsor":39,"locationsCount":42},"100616087","app-assisted-swallowing-program-after-oral-cancer-surgery-100616087",false,"NCT07301047","App-Assisted Swallowing Program After Oral Cancer Surgery","AASP","Inclusion Criteria:\n\n* Willing to sign a written informed consent form\n* Diagnosed with oral cancer\n* Hospitalized for first-time oral cancer tumor resection and flap reconstruction surgery\n* Aged 18 years or older\n* Conscious and mentally clear\n* Able to communicate in Mandarin or Taiwanese\n\nExclusion Criteria:\n\n* Diagnosed by a physician with poor postoperative wound healing that prevents participation in oral rehabilitation exercises\n* Unable to perform oral rehabilitation exercises within one week after surgery, as determined by a physician\n\nWithdrawal Criteria:\n\n-Participants who withdraw consent at any time during the study will be excluded from further participation","ALL","18 Years",{"count":19,"type":20},72,"ESTIMATED","INTERVENTIONAL",[23],"NA","This study aims to examine the effects of a swallowing care program combined with an exercise mobile application (App) on swallowing function, anxiety, and quality of life in patients with oral cancer after flap reconstruction surgery. The goal is to determine whether integrating App-based swallowing exercises into postoperative care can improve rehabilitation outcomes compared with conventional care alone.\n\nA purposive sampling method will be used to recruit 72 participants from the surgical wards of a medical center in northern Taiwan. Eligible patients scheduled for oral cancer tumor resection and flap reconstruction will be identified through consultation with plastic surgeons. After screening and informed consent, participants will be assigned to a control group or an experimental group, with approximately 36 patients in each group.\n\nThe control group will receive routine ward education and standard postoperative nursing care, while the experimental group will receive the same care plus an additional intervention using a swallowing exercise App. The intervention will begin on postoperative day 7, guided by the researcher. Follow-up assessments will be conducted during outpatient visits at postoperative week 4 and week 12. To minimize potential interference between participants, data collection will be performed sequentially-first for the control group, followed by the experimental group.\n\nData will be collected through self-administered questionnaires or researcher-assisted interviews, including a demographic survey, the Postoperative Oral Dysfunction-10 (POD-10), the Functional Oral Intake Scale (FOIS), a Visual Analog Scale for Anxiety, and the EORTC QLQ-H\\&N35 questionnaire for quality of life. Each assessment will take approximately 20-30 minutes. Participants may withdraw from the study at any time without penalty.\n\nDescriptive statistics will be used to summarize participant characteristics. The chi-square test and independent t-test will be used to examine group homogeneity. Paired t-tests will be applied to evaluate within-group changes in swallowing function, anxiety, and quality of life before and after the intervention. The results of this study are expected to provide empirical evidence on the effectiveness of App-assisted swallowing rehabilitation for patients with oral cancer following reconstructive surgery, supporting the development of innovative, technology-based postoperative care models.",[26,27,28],"Oral Cancer","Reconstructive Surgery","Postoperative",[26,28,27],"NOT_YET_RECRUITING","2025-12-23",{"date":33,"type":34},"2025-12-24","ACTUAL",{"date":36,"type":20},"2026-01-01",{"date":38,"type":20},"2026-12-31",{"name":40,"class":41},"Chang Gung Memorial Hospital","OTHER",1,{"id":44,"slug":45,"hasResults":11,"nctId":46,"briefTitle":47,"officialTitle":47,"acronym":4,"eligibilityCriteria":48,"healthyVolunteers":11,"sex":16,"minAge":4,"maxAge":4,"enrollmentInfo":49,"targetDuration":4,"studyType":51,"phases":4,"briefSummary":52,"conditions":53,"keywords":4,"overallStatus":55,"whyStopped":4,"lastUpdateSubmitDate":56,"lastUpdatePostDateStruct":57,"startDateStruct":59,"completionDateStruct":61,"leadSponsor":63,"locationsCount":42},"100615664","postoperative-management-of-patients-undergoing-head-and-neck-microvascular-free-flap-reconstructive-surgery-is-admission-to-an-intensive-care-unit-necessary-100615664","NCT07295548","Postoperative Management of Patients Undergoing Head and Neck Microvascular Free Flap Reconstructive Surgery: is Admission to an Intensive Care Unit Necessary?","Inclusion Criteria:\n\n* patients undergoing Head and Neck oncological demolitive surgery and reconstruction using free or pedicled flaps at the Fondazione IRCCS Policlinico San Matteo, Pavia\n\nExclusion Criteria:\n\n* patients treated for Head and Neck cancer without flap reconstruction (e.g., only chemotherapy-radiotherapy, only radiotherapy, only immunotherapy).",{"count":50,"type":20},192,"OBSERVATIONAL","The aim of our study is to assess if patients undergoing head and neck free flap reconstructive surgery admitted to the ICU have equivalent postoperative outcomes to those admitted to an Otolaryngology specialty ward",[27,54],"Head and Neck Microvascular Free Flap","RECRUITING","2025-12-16",{"date":58,"type":34},"2025-12-19",{"date":60,"type":34},"2025-10-13",{"date":62,"type":20},"2027-10-13",{"name":64,"class":41},"Fondazione IRCCS Policlinico San Matteo di Pavia",{"id":66,"slug":67,"hasResults":11,"nctId":68,"briefTitle":69,"officialTitle":70,"acronym":4,"eligibilityCriteria":71,"healthyVolunteers":11,"sex":72,"minAge":17,"maxAge":73,"enrollmentInfo":74,"targetDuration":4,"studyType":51,"phases":4,"briefSummary":76,"conditions":77,"keywords":4,"overallStatus":55,"whyStopped":4,"lastUpdateSubmitDate":81,"lastUpdatePostDateStruct":82,"startDateStruct":84,"completionDateStruct":86,"leadSponsor":87,"locationsCount":42},"100441776","the-association-between-radiation-dermatitis-and-skin-microbiome-in-breast-cancer-patients-100441776","NCT05032768","The Association Between Radiation Dermatitis and Skin Microbiome in Breast Cancer Patients","The Association Between Radiation Dermatitis and Skin Microbiome in Breast Cancer Patients Receiving Radiation After Mastectomy and Reconstructive Surgery","Inclusion Criteria:\n\n1. Female patients\n2. Invasive breast cancer confirmed by pathology\n3. Underwent mastectomy and breast reconstruction\n4. Radiotherapy after breast reconstruction\n5. ECOG score 0-1\n6. Signed informed consent\n\nExclusion Criteria:\n\n1. Previous breast or chest radiotherapy\n2. Other serious skin diseases (systemic lupus erythematosus, skin sclerosis, et al) and cannot receive radiotherapy\n3. Pregnant women\n4. Patients who are unwilling or unable to receive regular follow-up.","FEMALE","70 Years",{"count":75,"type":20},100,"The breast cancer patients who received radiotherapy after mastectomy and breast reconstruction will be enrolled. The skin microbiome before radiotherapy and its changes after radiotherapy will be analyzed systematically to find out whether the skin microbiome is associated with the severity of radiation dermatitis.",[78,79,80,27],"Radiation Dermatitis","Skin Microbiome","Breast Cancer","2021-09-01",{"date":83,"type":34},"2021-09-02",{"date":85,"type":34},"2021-01-01",{"date":38,"type":20},{"name":88,"class":41},"Fudan University",{"id":90,"slug":91,"hasResults":11,"nctId":92,"briefTitle":93,"officialTitle":94,"acronym":95,"eligibilityCriteria":96,"healthyVolunteers":11,"sex":72,"minAge":17,"maxAge":4,"enrollmentInfo":97,"targetDuration":4,"studyType":51,"phases":4,"briefSummary":99,"conditions":100,"keywords":4,"overallStatus":55,"whyStopped":4,"lastUpdateSubmitDate":102,"lastUpdatePostDateStruct":103,"startDateStruct":105,"completionDateStruct":107,"leadSponsor":109,"locationsCount":111},"100382607","aft-introduction-of-a-full-breast-reconstructive-method-100382607","NCT04261829","AFT: Introduction of a Full Breast Reconstructive Method","Autologous Fat Transfer: Introduction of a Full Breast Reconstructive Method","BREAST-II","Inclusion Criteria:\n\n* Female gender\n* Age of 18 years and older\n* History or in candidate for a mastectomy procedure in the near future\n* Patients undergoing preventive mastectomy\n* Patients' choice to undergo a breast reconstruction\n* Wanting to participate in this study\n* Patient is able to wear the external expansion device\n\nExclusion Criteria:\n\n* Active smoker or a history of smoking 4 weeks prior to surgery\n* Current substance abuse\n* History of lidocaine allergy\n* History of silicone allergy\n* 4 weeks or less after chemotherapy\n* History of radiation therapy in the breast region\n* Oncological treatment includes radiotherapy after mastectomy\n* Kidney disease\n* Steroid dependent asthma (daily or weekly) or other diseases\n* Immune-suppressed or compromised disease\n* Uncontrolled diabetes\n* BMI\\>30\n* Large breast size (i.e. larger than cup C), unless the patient prefers reduction of the contralateral side towards Cup C\n* Extra-capsular silicone leaking from the encapsulated implant from a previous breast reconstruction\n* The treating plastic surgeon has strong doubts on the patient's treatment compliance",{"count":98,"type":20},350,"A multicentre prospective cohort study will monitor the efficacy and safety of Autologous Fat Transfer (AFT) with pre-expansion. AFT will be evaluated in terms of quality of life, aesthetic result, complications, oncological safety and cost-effectiveness. It follows the BREAST trial, the randomised controlled trial comparing AFT with implant-based reconstruction. In this study, patients all receive AFT.",[80,27,101],"Breast Reconstruction","2021-07-22",{"date":104,"type":34},"2021-07-29",{"date":106,"type":34},"2020-12-09",{"date":108,"type":20},"2026-10",{"name":110,"class":41},"Maastricht University Medical Center",8]