[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"rectal-neuroendocrine-neoplasm\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:rectal-neuroendocrine-neoplasm":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,42],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":4,"briefSummary":22,"conditions":23,"keywords":4,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":30,"lastUpdatePostDateStruct":31,"startDateStruct":34,"completionDateStruct":36,"leadSponsor":38,"locationsCount":41},"100624525","advanced-endoscopic-resections-for-rectal-neoplasms-100624525",false,"NCT07410767","Advanced Endoscopic Resections for Rectal Neoplasms","Adoption of Advanced Endoscopic Resection Methods in the Treatment of Rectal Neoplasms","Inclusion Criteria:\n\n* Patients with rectal neoplasms treated by advanced endoscopic resection\n\nExclusion Criteria:\n\n* hybrid resection performed\n* full-thickness resection performed\n* essential procedural or outcome data were unavailable","ALL","18 Years",{"count":19,"type":20},300,"ESTIMATED","OBSERVATIONAL","This study evaluates how advanced endoscopic resection techniques affect treatment outcomes in adults with rectal cancer.\n\nRectal cancer has traditionally been treated with standard abdominal surgery. Newer endoscopic techniques allow removal of selected early tumors and may reduce treatment-related complications. However, their effectiveness and safety in tumors with deeper invasion are not yet fully established.\n\nThis multicenter retrospective observational study uses existing medical records from adults who underwent endoscopic or surgical resection of rectal tumors between 2015 and 2025. Researchers will analyze anonymized information on procedures performed and treatment outcomes to assess the safety and effectiveness of advanced endoscopic approaches.\n\nThe results of this study may help guide treatment selection and improve care for people with rectal cancer.",[24,25,26,27,28],"Rectal Cancer","Rectal Adenocarcinoma","Rectal Adenoma","Rectal Neuroendocrine Neoplasm","Recurrent Rectal Adenocarcinoma","NOT_YET_RECRUITING","2026-02-13",{"date":32,"type":33},"2026-02-18","ACTUAL",{"date":35,"type":20},"2026-03-01",{"date":37,"type":20},"2026-04-30",{"name":39,"class":40},"Jagiellonian University","OTHER",1,{"id":43,"slug":44,"hasResults":11,"nctId":45,"briefTitle":46,"officialTitle":46,"acronym":4,"eligibilityCriteria":47,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":48,"enrollmentInfo":49,"targetDuration":4,"studyType":51,"phases":52,"briefSummary":54,"conditions":55,"keywords":4,"overallStatus":56,"whyStopped":4,"lastUpdateSubmitDate":57,"lastUpdatePostDateStruct":58,"startDateStruct":60,"completionDateStruct":62,"leadSponsor":64,"locationsCount":41},"100537551","lateral-pelvic-lymph-node-dissection-for-rectal-neuroendocrine-neoplasms-undergoing-laparoscopic-total-mesenteric-excision-100537551","NCT06279299","Lateral Pelvic Lymph Node Dissection for Rectal Neuroendocrine Neoplasms Undergoing Laparoscopic Total Mesenteric Excision","Inclusion Criteria:\n\n1. Biopsy proven rectal neuroendocrine neoplasm (neuroendocrine tumor and carcinoma);\n2. Meets any one of the following conditions:\n\n   * Preoperative imaging examinations reveal that the maximum diameter of the tumor is greater than 2cm.\n   * Preoperative imaging examinations reveal that the maximum diameter of the tumor is between 1-2cm and the clinical staging is T2 or higher.\n   * Preoperative imaging examinations reveal that the maximum diameter of the tumor is between 1-2cm and is categorized as Grade 3 differentiation.\n   * Recurrence after local excision under endoscopy.\n3. Eastern Cooperative Oncology Group(ECOG) performance score ≤ 1;\n4. Written informed consent;\n\nExclusion Criteria:\n\n1. Complete intestinal obstruction;\n2. Hepatitis activity and peripheral neuropathy (such as peripheral neuritis, pseudo meningitis, motor neuritis, and sensory impairment);\n3. Significant organ dysfunction or other significant diseases, including clinically relevant coronary artery disease, cardiovascular disease, or myocardial infarction within the 12 months before enrollment; severe neurological or psychiatric history; severe infection; active disseminated intravascular coagulation；\n4. Pregnancy or breastfeeding;\n5. Alcohol abuse or drug addiction;\n6. Concurrent uncontrolled medical condition;","75 Years",{"count":50,"type":20},30,"INTERVENTIONAL",[53],"NA","The purpose of this study is to investigate the metastatic status of lateral pelvic lymph nodes in rectal neuroendocrine neoplasms (rNENs) undergoing laparoscopic total mesenteric excision (TME). The hypothesis is that the rate of lateral lymph node metastasis is underestimated in rNENs undergoing TME, necessitating concurrent lateral Pelvic lymph node dissection.",[27],"RECRUITING","2024-02-26",{"date":59,"type":33},"2024-02-28",{"date":61,"type":33},"2022-08-01",{"date":63,"type":20},"2028-08-01",{"name":65,"class":40},"National Cancer Center, China"]