[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"rectal-neuroendocrine-tumors\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:rectal-neuroendocrine-tumors":26},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,42],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":29,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":31,"lastUpdatePostDateStruct":32,"startDateStruct":35,"completionDateStruct":37,"leadSponsor":39,"locationsCount":5},"100638977","two-different-endoscopic-treatments-for-rectal-neuroendocrine-neoplasms-100638977",false,"NCT07612748","Two Different Endoscopic Treatments for Rectal Neuroendocrine Neoplasms","Retrospective Comparative Study of Two Different Endoscopic Treatments for Rectal Neuroendocrine Neoplasms","Inclusion Criteria:\n\n* Patients undergoing endoscopic treatment for rectal neuroendocrine neoplasms.\n* Lesion diameter less than 2 cm.\n* Preoperative auxiliary examinations indicating no peripheral lymph node or distant metastasis.\n* Endoscopic surgical approach limited to ESD or EPMR.\n\nExclusion Criteria:\n\n* Use of non-ESD or non-EPMR endoscopic techniques, such as ligation-assisted resection or Endoscopic Mucosal Resection (EMR).\n* Presence of other conditions deemed by the investigator to be unsuitable for participation in this study.\n* Patient or family refusal to participate.","ALL","18 Years",{"count":19,"type":20},483,"ESTIMATED","INTERVENTIONAL",[23],"NA","The aim is to compare the safety and efficacy of endoscopic submucosal dissection (ESD) versus endoscopic partial muscle resection（ EPMR） for the treatment of rectal neuroendocrine neoplasms (R-NENs), thereby providing guidance for optimizing therapeutic strategies. The investigators retrospectively analyzed consecutive patients with R-NENs who underwent endoscopic resection at our center between January 2020 and February 2026. Patients were assigned to either the ESD group or the EPMR group. Baseline characteristics and perioperative outcomes were compared, including the number of lesions, maximum lesion diameter, single-lesion procedure time, postoperative complications, positive margin rate, pathological staging, lymphovascular invasion, and the need for additional therapies.",[26,27,28],"Rectal Neuroendocrine Tumors","ESD","EPMR",[27,28],"RECRUITING","2026-05-31",{"date":33,"type":34},"2026-06-03","ACTUAL",{"date":36,"type":34},"2026-06-01",{"date":38,"type":20},"2027-12-01",{"name":40,"class":41},"Jilin University","OTHER",{"id":43,"slug":44,"hasResults":11,"nctId":45,"briefTitle":46,"officialTitle":47,"acronym":4,"eligibilityCriteria":48,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":49,"enrollmentInfo":50,"targetDuration":4,"studyType":21,"phases":52,"briefSummary":53,"conditions":54,"keywords":55,"overallStatus":59,"whyStopped":4,"lastUpdateSubmitDate":60,"lastUpdatePostDateStruct":61,"startDateStruct":63,"completionDateStruct":65,"leadSponsor":67,"locationsCount":4},"100621622","modified-double-snare-assisted-emr-mds-emr-vs-esd-for-rectal-neuroendocrine-tumors-smaller-than-1cm-100621622","NCT07373015","Modified Double Snare Assisted EMR (mDS-EMR) VS ESD for Rectal Neuroendocrine Tumors Smaller Than 1cm","Comparision of Safety and Efficacy Between Modified Double Snare Assisted EMR (mDS-EMR) and ESD for Rectal Neuroendocrine Tumors Smaller Than 1cm: a Prospective Non-inferiority Randomized Controlled Study","Inclusion Criteria:\n\n1. Typical rectal neuroendocrine tumors by endoscopy (within 15cm from the anal verge, yellowish subepithelial elevation with a smooth surface, and dilated blood vessels in some areas).\n2. The maximum diameter of the lesion is smaller than 1cm by preoperative endoscopic assessment.\n3. Lesion is located within the mucosal and submucosal layer by preoperative endoscopic assessment.\n4. Patients can understand and sign the informed consent.\n\nExclusion Criteria:\n\n1. Poor coagulation function(PT\\>15 seconds or APTT\\>45 seconds or INR\\>2.0)\n2. With severe cardiovascular or cerebrovascular diseases and cannot tolerate operation( with a history of stroke or myocardial infarction within the past month or with severe heart failure and cardiac function grade III)\n3. Indication of metastasis by preoperative imaging examinations\n4. With more than or equal to 2 rectal neuroendocrine tumors\n5. With other complications that are not suitable for this study by multidisciplinary team assesment\n6. Cases of recurrence after operation for neuroendocrine tumors","85 Years",{"count":51,"type":20},118,[23],"The aim of this study is evaluating and safety and efficacy between the modified double snare EMR and ESD. It is intended to prove that for rectal neuroendocrine tumors within 1 cm, the complete resection rate of the mDS-EMR is not inferior to that of ESD, but may with shorter operation time, lower complication rate and lower treatment cost.",[26],[56,57,58],"Endoscopic Submucosal Dissection","Endoscopic Mucosal Resection","rectal neuroendocrine tumor","NOT_YET_RECRUITING","2026-01-22",{"date":62,"type":34},"2026-01-28",{"date":64,"type":20},"2026-01-01",{"date":66,"type":20},"2028-06-30",{"name":68,"class":41},"The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School"]