[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"rectal-prolapse\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:rectal-prolapse":26},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,5,0,[8,47,77,106,129],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":4,"enrollmentInfo":17,"targetDuration":4,"studyType":20,"phases":21,"briefSummary":23,"conditions":24,"keywords":29,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":35,"lastUpdatePostDateStruct":36,"startDateStruct":39,"completionDateStruct":41,"leadSponsor":43,"locationsCount":46},"100463933","evaluation-of-single-port-sp-robotic-technology-in-colorectal-surgery-100463933",false,"NCT05321134","Evaluation of SINGLE PORT (SP) Robotic Technology in Colorectal Surgery","Inclusion Criteria:\n\n* The subject is male or female, greater than or equal to 18 years of age. If female, the subject has a negative urine pregnancy test and is not lactating, or has not been of childbearing potential for at least 3 months prior to use of study product. To be considered to be not of childbearing potential, the subject must be postmenopausal for at least 2 years; have had a hysterectomy or bilateral tubal ligation, or be proven to be otherwise incapable of pregnancy. If of childbearing potential, the subject must have been practicing one of the following methods of contraception consistently for at least 1 month prior to study entry and agree to continue practicing it during the study: hormonal contraceptives, intrauterine device, spermicide and barrier, spouse\u002Fpartner sterility; or is practicing abstinence and agrees to continue abstinence or to start an acceptable method of contraception from the above list if sexual activity commences.\n* There is documentation of a colorectal diagnosis requiring operative interventions with clinical plans for a robotic operation.\n* For robotic transanal procedures, patients who would meet standard guidelines for a transanal procedures (T1N0 rectal adenocarcinoma, Precancerous adenomas, and localized neuroendocrine tumors) distal to 15 cm from the anal verge.\n* The subject is in good general health as evidenced by medical history and physical examination\n* The subject is able and willing to provide written informed consent.\n* The subject agrees to comply with the requirements of the protocol and complete study measures.\n* The subject has stable residence and telephone.\n\nExclusion Criteria:\n\n* The subject is child less than 18 years of age\n* The subject is a female who is pregnant or lactating\n* The subject falls under the American Society of Anesthesia Class IV (Patients with severe systemic disease that is a constant threat to life).\n* The subject falls under American Society of Anesthesia Class V (Moribund patients who is not expected to survive without the operation)\n* The subject has a history of clinically significant renal, hepatic, neurological, cardiac or chronic pulmonary disease that in the judgment of the investigator precludes participation.\n* The subject has advanced\u002F Stage IV cancer\n* The subject has received neo-adjuvant chemotherapy or radiation therapy\n* The subject requires an emergency operation.\n* The subject is unable to fully comprehend or consent to the study\n* The subject is unwilling to be available for follow-up assessments.","ALL","18 Years",{"count":18,"type":19},25,"ESTIMATED","INTERVENTIONAL",[22],"NA","Currently a multiport robotic surgery platform (Intuitive Xi) is widely available and used for colorectal surgery indications. A Single port platform (Intuitive SP) is FDA approved for Head and Neck and Urology but has not been widely used in colorectal surgery. This study seeks to evaluate the safe and effective use of the SP platform for colorectal surgery indications.",[25,26,27,28],"Colo-rectal Cancer","Rectal Prolapse","Colostomy Stoma","Colorectal Disorders",[30,31,32,33],"robotic surgery","colorectal surgery","single port","Intuitive SP platform","RECRUITING","2026-05-26",{"date":37,"type":38},"2026-05-29","ACTUAL",{"date":40,"type":38},"2022-04-28",{"date":42,"type":19},"2028-04",{"name":44,"class":45},"University of California, Davis","OTHER",1,{"id":48,"slug":49,"hasResults":11,"nctId":50,"briefTitle":51,"officialTitle":51,"acronym":4,"eligibilityCriteria":52,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":53,"enrollmentInfo":54,"targetDuration":4,"studyType":20,"phases":56,"briefSummary":57,"conditions":58,"keywords":4,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":68,"lastUpdatePostDateStruct":69,"startDateStruct":71,"completionDateStruct":73,"leadSponsor":75,"locationsCount":46},"100587283","prospective-evaluation-of-cornerstone-robotics-sentire-surgical-system-in-major-gastrointestinal-and-urologic-surgery-100587283","NCT06926374","Prospective Evaluation of Cornerstone Robotics Sentire Surgical System in Major Gastrointestinal and Urologic Surgery","General Inclusion Criteria for All Procedures:\n\n* Body mass index \\\u003C35 kg\u002Fm2\n* Suitable for the listed minimally invasive surgical procedures for treatment of respective diseases\n* Willingness to participate as demonstrated by giving informed consent\n\nGeneral Exclusion Criteria for All Procedures:\n\n* Contraindication to general anesthesia\n* Severe concomitant illness that drastically shortens life expectancy or increases risk of therapeutic intervention\n* Untreated active infection\n* Noncorrectable coagulopathy\n* Presence of another malignancy or distant metastasis\n* Emergency surgery\n* Vulnerable population (e.g., mentally disabled, pregnancy)\n\nRobotic Colorectal Resection\n\nInclusion Criteria:\n\n\\- Adenocarcinoma or large adenoma (not amenable to endoscopic removal) located at the colorectum (from the cecum to the anal verge) amenable to minimally invasive surgery\n\nExclusion Criteria:\n\n* T4 tumor\n* Recurrent tumor\n* Extensive previous abdominal surgery precluding minimally invasive surgery\n\nRobotic Transanal Total Mesorectal Excision\n\nInclusion Criteria:\n\n\\- Mid\u002Flow rectal adenocarcinoma located \\\u003C12 cm from the anal verge\n\nExclusion Criteria:\n\n* T4 tumor or involvement of circumferential resection margin even after neoadjuvant therapy\n* Tumor requiring multivisceral resection\n* Tumor requiring abdominoperineal resection; recurrent rectal tumor\n* T1 tumor that can be treated by local excision\n* Extensive previous abdominal surgery\n\nRobotic Rectopexy\n\nInclusion Criteria:\n\n* Clinically diagnosed with previously untreated and uncomplicated rectal prolapse or enterocele\n\nExclusion Criteria:\n\n\\- Extensive previous abdominal surgery precluding minimally invasive surgery\n\nRadical Prostatectomy\n\nInclusion Criteria:\n\n\\- Clinically diagnosed with nonmetastatic adenocarcinoma of prostate\n\nExclusion Criteria:\n\n\\- Previous history of prostate surgery (e.g., transurethral resection of prostate)\n\nTotal or Partial Nephrectomy\n\nInclusion Criteria:\n\n\\- Clinically diagnosed with nonmetastatic kidney cancer\n\nExclusion Criteria:\n\n* Previous ipsilateral kidney surgery\n* Complex kidney anatomy (e.g., horseshoe kidney, complex renal vascular anatomy)\n\nRadical Cystectomy\n\nInclusion Criteria:\n\n\\- Clinically diagnosed with nonmetastatic bladder cancer\n\nRobotic Esophageal Hiatal Surgery and Fundoplication\n\nInclusion Criteria:\n\n\\- Clinically diagnosed with Hiatal Hernia and \u002F or Gastroesophageal reflux disease amendable to fundoplication\n\nExclusion Criteria:\n\n\\- Previous history of laparotomy precluding minimally invasive surgery\n\nRobotic Gastrectomy\n\nInclusion Criteria:\n\n\\- Clinical diagnosis of gastric tumor (Adenocarcinoma or Gastrointestinal Stromal Tumor (GIST)) amendable to minimally invasive radical gastrectomy\n\nExclusion Criteria:\n\n\\- Previous history of laparotomy precluding minimally invasive surgery\n\nRobotic Esophagectomy\n\nInclusion Criteria:\n\n\\- Clinical diagnosis of carcinoma of esophagus amendable to minimally invasive esophagectomy\n\nExclusion Criteria:\n\n\\- Esophageal carcinoma after definitive chemoradiotherapy and indicated for salvage esophagectomy\n\nRobotic Cholecystectomy\n\nInclusion Criteria:\n\n\\- Symptomatic gallbladder stones clinically indicated for laparoscopic cholecystectomy\n\nExclusion Criteria:\n\n* Acute cholecystitis\n* Previous history of abdominal surgery","80 Years",{"count":55,"type":19},90,[22],"Robotic assisted surgery has been performed for more than two decades with good success and safety profile. However, there was only one dominating robotic surgical system available in the past which led to high cost for robotic surgery. Recently, a new robotic surgical system (Sentire Robotic Surgical System) was introduced by researchers of The Chinese University of Hong Kong (CUHK). This new robotic surgical system aims to achieve similar outcomes and standards of robotic surgery performed using the dominating system but with a significantly lower cost. The technologic innovation and development of this new robotic system is made by the Cornerstone Robotics Limited, which is based in Hong Kong. In a pilot clinical study conducted at Prince of Wales Hospital involving 55 patients, the Sentire Robotic Surgical System had demonstrated high success rate with minimal complications in patients who underwent robotic colorectal, upper gastrointestinal, and urologic surgery. Researchers of CUHK would therefore like to conduct another prospective study to further evaluate the efficacy and safety of Sentire Surgical System C1000 in major gastrointestinal and urologic surgery with expanded indications. It is believed that the results of this study will provide data to support its use for wide range of procedures with minimal access trauma, for the benefit of patients. This system will also lead to a wider range of clinical application for minimally invasive surgery with a cost-effective model.",[59,26,60,61,62,63,64,65,66,67],"Colorectal Carcinoma","Prostate Cancer (Adenocarcinoma)","Bladder Cancer","Kidney Cancer","Hiatal Hernia With Gastroesophageal Reflux Disease","GIST - Gastrointestinal Stromal Tumor","Esophageal Cancer","Gallstones","Gastric Cancer","2025-04-11",{"date":70,"type":38},"2025-04-16",{"date":72,"type":38},"2025-03-25",{"date":74,"type":19},"2027-04",{"name":76,"class":45},"Chinese University of Hong Kong",{"id":78,"slug":79,"hasResults":11,"nctId":80,"briefTitle":81,"officialTitle":82,"acronym":4,"eligibilityCriteria":83,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":4,"enrollmentInfo":84,"targetDuration":4,"studyType":86,"phases":4,"briefSummary":87,"conditions":88,"keywords":89,"overallStatus":96,"whyStopped":4,"lastUpdateSubmitDate":97,"lastUpdatePostDateStruct":98,"startDateStruct":100,"completionDateStruct":102,"leadSponsor":104,"locationsCount":4},"100551085","foam-functional-outcome-after-ventral-mesh-rectopexy-100551085","NCT06455501","FOAM: Functional Outcome After Ventral Mesh Rectopexy","FOAM: Functional Outcome After Ventral Mesh Rectopexy, Prospective Cohort Study","Inclusion Criteria:\n\n* full-thickness rectal prolapse\n* the surgeon agrees that ventral mesh rectopexy is needed for the condition\n* capable of participating in follow-up visits and answering questionnaires\n* informed consent\n\nExclusion Criteria:\n\n* patient below 18 years of age\n* ongoing pregnancy\n* inability to understand the Swedish language\n* dementia or other cognitive disorder that unables informed consent",{"count":85,"type":19},70,"OBSERVATIONAL","Rectal prolapse is a protrusion of rectal wall through the anus. A surgical technique called Ventral mesh rectopexy has become a standard procedure for this condition in many centers.\n\nThe goal of this trial is to investigate functional outcome, recurrence rates and complications after ventral mesh rectopexy. The main question it aims to answer is:\n\n\\- Do bowel function, quality of life and sexual function improve after Ventral mesh rectopexy?\n\nParticipants will:\n\n* be asked to fill in questionaires before surgery, 3-6 months after surgery and 12 months after surgery.\n* be examined by a surgeon 3-6 months, 12 months and 3 years after surgery.",[26],[90,91,92,93,94,95],"Ventral mesh rectopexy","Laparoscopic ventral mesh rectopexy","Quality of Life","Bowel function","Recurrence","Sexual function","NOT_YET_RECRUITING","2024-06-11",{"date":99,"type":38},"2024-06-12",{"date":101,"type":19},"2024-09-01",{"date":103,"type":19},"2029-08-31",{"name":105,"class":45},"Uppsala University",{"id":107,"slug":108,"hasResults":11,"nctId":109,"briefTitle":110,"officialTitle":111,"acronym":4,"eligibilityCriteria":112,"healthyVolunteers":11,"sex":15,"minAge":4,"maxAge":4,"enrollmentInfo":113,"targetDuration":4,"studyType":86,"phases":4,"briefSummary":115,"conditions":116,"keywords":118,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":120,"lastUpdatePostDateStruct":121,"startDateStruct":123,"completionDateStruct":125,"leadSponsor":127,"locationsCount":46},"100375488","caes-for-internal-hemorrhoids-and-rectal-prolapse-100375488","NCT04169152","CAES for Internal Hemorrhoids and Rectal Prolapse","Cap-assisted Endoscopic Sclerotherapy for Internal Hemorrhoids and Rectal Prolapse: a National Multi-centre Prospective Cohort Study","Inclusion Criteria:\n\n1. Grade I-III internal hemorrhoids (with or without external hemorrhoids) or\u002Fand recal prolapse.\n2. Patients with bowel preparation.\n\nExclusion Criteria:\n\n1. History of anoscopic\u002Fendoscopic sclerotherapy.\n2. Acute thrombotic hemorrhoids or grade IV internal hemorrhoids.\n3. Anal stenosis, perianal and perirectal abscess, anal fissure, fistula, fecal incontinence and other severe complications (such as severe anal pain).\n4. Inflammatory bowel disease.\n5. Full-thickness rectal prolapse through the anus.\n6. Acute diarrhea in the past 24 hours.\n7. Hypertensive with uncontrolled blood pressure.\n8. Cerebrovascular accident.\n9. Blood coagulation dysfunction.\n10. Pregnant women.\n11. Mental disorders.\n12. Decompensated cirrhosis.",{"count":114,"type":19},10000,"Cap-assisted endoscopic sclerotherapy (CAES) is a new interventional therapy for internal hemorrhoids and rectal prolapse under colonoscopy. However, the long-term efficacy and safety of CAES in the treatment of internal hemorrhoids and rectal prolapse are still not clear due to the lack of large sample studies. Therefore, a nationwide multi-center, large sample, prospective and cohort study was designed to evaluate the efficacy and safety of CAES in the treatment of internal hemorrhoids and rectal prolapse, to provide reliable evidence for popularization of this minimally invasive technology.",[117,26],"Internal Hemorrhoid",[119,117,26],"Cap-assisted endoscopic sclerotherapy","2024-04-01",{"date":122,"type":38},"2024-04-02",{"date":124,"type":38},"2019-12-30",{"date":126,"type":19},"2028-06-30",{"name":128,"class":45},"Faming Zhang",{"id":130,"slug":131,"hasResults":11,"nctId":132,"briefTitle":133,"officialTitle":133,"acronym":134,"eligibilityCriteria":135,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":4,"enrollmentInfo":136,"targetDuration":138,"studyType":86,"phases":4,"briefSummary":139,"conditions":140,"keywords":146,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":151,"lastUpdatePostDateStruct":152,"startDateStruct":154,"completionDateStruct":156,"leadSponsor":158,"locationsCount":5},"100509817","multicenter-ventral-mesh-rectopexy-registry-collaborative-100509817","NCT05918367","Multicenter Ventral Mesh Rectopexy Registry Collaborative","M2R2","Inclusion Criteria:\n\n* Diagnosis of posterior pelvic organ prolaps planned for laparoscopie or robotic ventral mesh rectopexy with or without concomittant surgery.\n* All patients 18 years or older and are able to complete a written informed conscent are eligble for inclusion.\n\nExclusion Criteria:\n\n1. Inability to complete a written informed conscent\n2. Pregnant women\n3. No email adress available to send the questionnaires to\n4. Language barrier or impossiblity to fill in the questionnaires (at the discretion oft he treating physician)",{"count":137,"type":19},200,"5 Years","The goal of this multicenter observational study is to collect data prospectively of patients with pelvic organ prolapse undergoing ventral mesh rectopexy (as well as rectoceles, entero-\u002Fsigmoidoceles\u002F intussusception\u002F rectal prolapse or combined) by laparoscopy or robotic surgery and to evaluate the longterm functional outcomes.\n\nSecondly complications (mesh erosions, recurrence, reoperations) are evaluated.\n\nFollowing main questions will be analysed - other can follow in consultation with the collaborative\n\n1. Is VMR the technique of choice for treatment of rectoceles? Functional results - recurrence - mesh related complications\n2. Has a perineal descent an impact on the functional outcome of ventral mesh rectopexy perfored for external rectal prolaps, internal rectal prolaps, rectocele, enterocele, sigmoidcele or combined pelvic organ prolapse?",[141,142,143,26,144,145],"Pelvic Organ Prolapse","Rectocele","Enterocele","Descending Perineum Syndrome","Surgery",[147,148,149,150],"Posterior pelvic organ prolapse","descending perineum","ventral mesh rectopexy","functional outcome","2023-10-23",{"date":153,"type":38},"2023-10-25",{"date":155,"type":38},"2023-09-25",{"date":157,"type":19},"2032-09-30",{"name":159,"class":45},"University Hospital, Antwerp"]