[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"rectocele\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:rectocele":32},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,4,0,[8,57,92,123],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":38,"overallStatus":44,"whyStopped":4,"lastUpdateSubmitDate":45,"lastUpdatePostDateStruct":46,"startDateStruct":49,"completionDateStruct":51,"leadSponsor":53,"locationsCount":56},"100549201","biological-ovitex-versus-synthetic-graft-in-robotic-prolapse-surgery-100549201",false,"NCT06430931","Biological OviTex Versus Synthetic Graft in Robotic Prolapse Surgery","Biological OviTex Versus Synthetic Graft in Robotic Prolapse Surgery: a Multicentre, Phase 11-111, Partially Randomised Patient Preference Trial","ProTex","Inclusion Criteria:\n\n* Indication for VMR or SCR set by the treating surgeon\u002Fgynecologist in accordance to the current guidelines on rectal and pelvic prolapse;\n* Counselled for therapeutic options and given informed consent for VMR or SCR;\n* Counselled for different types of mesh (OviTex or Prolene) and randomisation;\n* Written informed consent for randomisation, OviTex implant or Prolene;\n* Written informed consent for observational data collection.\n\nExclusion Criteria:\n\n* Mentally incompetent patients (unable to fulfil questionnaires).\n* Allergy to ovine rumen.\n* A medical history of pelvic radiation therapy.\n* Scheduled for a redo-rectopexy.\n* A medical history of previously implanted pelvic floor meshes or native tissue.\n* Language barrier","ALL","18 Years",{"count":20,"type":21},184,"ESTIMATED","INTERVENTIONAL",[24],"NA","This prospective study aims to assess the efficacy of the OviTex 1S permanent mesh in pelvic floor surgery in comparison with the current standard polypropylene mesh.",[27,28,29,30,31,32,33,34,35,36,37],"Colorectal Disorders","Prolapse","Prolapse Rectal","Prolapse Genital","Prolapse Pelvic","Rectocele","Prolapse Uterus","Cystocele","Enterocele","Prolapse Bladder","Prolapse; Cervix",[28,39,40,41,42,43],"Abdominal prolapse Surgery","Biological mesh","OviTex","VMR","sacrocolporectopexy","RECRUITING","2025-12-31",{"date":47,"type":48},"2026-01-02","ACTUAL",{"date":50,"type":48},"2023-12-06",{"date":52,"type":21},"2027-07-01",{"name":54,"class":55},"Meander Medical Center","OTHER",1,{"id":58,"slug":59,"hasResults":11,"nctId":60,"briefTitle":61,"officialTitle":62,"acronym":4,"eligibilityCriteria":63,"healthyVolunteers":11,"sex":64,"minAge":18,"maxAge":65,"enrollmentInfo":66,"targetDuration":4,"studyType":22,"phases":68,"briefSummary":70,"conditions":71,"keywords":74,"overallStatus":44,"whyStopped":4,"lastUpdateSubmitDate":82,"lastUpdatePostDateStruct":83,"startDateStruct":85,"completionDateStruct":87,"leadSponsor":89,"locationsCount":91},"100404550","phase-3-efficacy-of-conservative-treatment-of-functional-defecatory-disorders-in-females-with-pelvic-organ-prolapse-100404550","NCT04547816","Efficacy of Conservative Treatment of Functional Defecatory Disorders in Females With Pelvic Organ Prolapse","Evaluation of Complex (Physical Therapy and Diet) Treatment of Functional Defecatory Disorders in Females With Pelvic Organ Prolapse","Inclusion Criteria:\n\n* Willingness to participate (signed informed consent form)\n* Females with rectocele I-II grade or rectocele I-II grade and internal rectal invagination and functional defecatory disorders (per Rome IV guidelines) confirmed on the basis of complex examination including high-resolution anorectal manometry\n\nExclusion Criteria:\n\n* rectocele III grade;\n* internal genitals prolapse;\n* history of abdominal or pelvic surgery that may impact bowel motility (excluding non-complicated appendectomy or laparoscopic cholecystectomy);\n* gynecological surgery that may influence sensory or reservoir function of rectum;\n* history of major cardiovascular events, or presence of current conditions that in case of participation of the patient in the study may put her at risk of exacerbation or complication;\n* start of any new concomitant medication with mechanisms of action that influence rectal motility, sensory function, muscle tone and\u002For contractility\n* inability to understand and\u002For follow the instructions to perform all the procedures required per protocol\n* general condition of the patient that make her ineligible by the discretion of the investigator","FEMALE","70 Years",{"count":67,"type":21},100,[69],"PHASE3","This study is planned to evaluate the efficacy of complex conservative treatment (including tibial neuromodulation, biofeedback therapy, special pelvic floor training and diet modification) in women with pelvic organ prolapse",[72,73,32],"Pelvic Floor Prolapse","Functional Constipation",[75,76,77,78,79,80,81],"pelvic floor prolapse","conservative treatment","functional disorders of defecation","rectocele","diet modification","biofeedback therapy","tibial neuromodulation","2025-08-01",{"date":84,"type":48},"2025-08-03",{"date":86,"type":48},"2020-07-01",{"date":88,"type":21},"2026-05-31",{"name":90,"class":55},"Federal State Budgetary Scientific Institution \"Federal Research Centre of Nutrition, Biotechnology",2,{"id":93,"slug":94,"hasResults":11,"nctId":95,"briefTitle":96,"officialTitle":97,"acronym":4,"eligibilityCriteria":98,"healthyVolunteers":11,"sex":64,"minAge":18,"maxAge":99,"enrollmentInfo":100,"targetDuration":4,"studyType":22,"phases":102,"briefSummary":103,"conditions":104,"keywords":107,"overallStatus":113,"whyStopped":4,"lastUpdateSubmitDate":114,"lastUpdatePostDateStruct":115,"startDateStruct":117,"completionDateStruct":119,"leadSponsor":121,"locationsCount":4},"100562556","fat-injection-for-rectocele-treatment-a-novel-approach-100562556","NCT06604702","Fat Injection for Rectocele Treatment: A Novel Approach","Fat Injection for Treatment of Rectocele a Novel Technique for Treatment of Tectocele","Inclusion Criteria:\n\n* Female patients aged between 18 and 60 years.\n* Diagnosis of rectocele confirmed by defecography, with a rectocele size of 2 cm (mild) to 4 cm (moderate).\n* Presenting with symptoms of obstructive defecation syndrome, including constipation, incomplete defecation, and\u002For vaginal bulge.\n* Able to provide written informed consent to participate in the study.\n\nExclusion Criteria:\n\n* Patients who have previously undergone surgical repair of rectocele.\n* Presence of thrombosed hemorrhoids.\n* History of sclerotherapy injection for rectocele.\n* Diagnosis of anal stenosis.\n* History of coagulopathy or current use of anticoagulant or antiplatelet medications.\n* Refusal or inability to provide informed consent.","60 Years",{"count":101,"type":21},25,[24],"This clinical trial aims to evaluate the effectiveness of autologous fat grafting as a novel treatment for rectocele, a condition characterized by the herniation of rectal tissue into the posterior vaginal wall. Women aged 18 to 60 years with mild to moderate rectocele, presenting with symptoms such as obstructive defecation or vaginal bulge, will undergo submucosal fat injections. The study will assess the procedure\\'s ability to alleviate symptoms and reduce prolapse recurrence. This prospective, single-arm trial will be conducted at Cairo University Hospitals.",[32,105,106],"Pelvic Organ Prolapse","Obstructive Defecation Syndrome",[32,108,109,110,111,105,112],"Pelvic Floor Dysfunction","Fat Grafting","Autologous Fat Injection","Obstructive Defecation","Vaginal Bulge","NOT_YET_RECRUITING","2024-09-17",{"date":116,"type":48},"2024-09-19",{"date":118,"type":21},"2024-10-20",{"date":120,"type":21},"2025-10-20",{"name":122,"class":55},"Cairo University",{"id":124,"slug":125,"hasResults":11,"nctId":126,"briefTitle":127,"officialTitle":127,"acronym":128,"eligibilityCriteria":129,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":130,"targetDuration":132,"studyType":133,"phases":4,"briefSummary":134,"conditions":135,"keywords":139,"overallStatus":44,"whyStopped":4,"lastUpdateSubmitDate":144,"lastUpdatePostDateStruct":145,"startDateStruct":147,"completionDateStruct":149,"leadSponsor":151,"locationsCount":153},"100509817","multicenter-ventral-mesh-rectopexy-registry-collaborative-100509817","NCT05918367","Multicenter Ventral Mesh Rectopexy Registry Collaborative","M2R2","Inclusion Criteria:\n\n* Diagnosis of posterior pelvic organ prolaps planned for laparoscopie or robotic ventral mesh rectopexy with or without concomittant surgery.\n* All patients 18 years or older and are able to complete a written informed conscent are eligble for inclusion.\n\nExclusion Criteria:\n\n1. Inability to complete a written informed conscent\n2. Pregnant women\n3. No email adress available to send the questionnaires to\n4. Language barrier or impossiblity to fill in the questionnaires (at the discretion oft he treating physician)",{"count":131,"type":21},200,"5 Years","OBSERVATIONAL","The goal of this multicenter observational study is to collect data prospectively of patients with pelvic organ prolapse undergoing ventral mesh rectopexy (as well as rectoceles, entero-\u002Fsigmoidoceles\u002F intussusception\u002F rectal prolapse or combined) by laparoscopy or robotic surgery and to evaluate the longterm functional outcomes.\n\nSecondly complications (mesh erosions, recurrence, reoperations) are evaluated.\n\nFollowing main questions will be analysed - other can follow in consultation with the collaborative\n\n1. Is VMR the technique of choice for treatment of rectoceles? Functional results - recurrence - mesh related complications\n2. Has a perineal descent an impact on the functional outcome of ventral mesh rectopexy perfored for external rectal prolaps, internal rectal prolaps, rectocele, enterocele, sigmoidcele or combined pelvic organ prolapse?",[105,32,35,136,137,138],"Rectal Prolapse","Descending Perineum Syndrome","Surgery",[140,141,142,143],"Posterior pelvic organ prolapse","descending perineum","ventral mesh rectopexy","functional outcome","2023-10-23",{"date":146,"type":48},"2023-10-25",{"date":148,"type":48},"2023-09-25",{"date":150,"type":21},"2032-09-30",{"name":152,"class":55},"University Hospital, Antwerp",5]