[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"recurrent-brain-neoplasm\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:recurrent-brain-neoplasm":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,42],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":4,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":30,"lastUpdatePostDateStruct":31,"startDateStruct":34,"completionDateStruct":36,"leadSponsor":38,"locationsCount":41},"100266956","electrocorticography-in-mapping-functional-brain-areas-during-surgery-in-patients-with-brain-tumors-100266956",false,"NCT02754544","Electrocorticography in Mapping Functional Brain Areas During Surgery in Patients With Brain Tumors","Pilot Investigation of Using Electrocorticogram (ECoG) in Predicting Eloquent Cortex and Post-Operative Functional Outcomes in Patients With Brain Tumors","Inclusion Criteria:\n\n* Patients undergoing a tumor resection at the University of Texas M. D. Anderson Cancer Center for a newly diagnosed as well as recurrent primary or metastatic brain tumor located in or adjacent to motor and\u002For speech brain areas\n* Patients \\>= 18 years of age\n* Signed informed consent\n\nExclusion Criteria:\n\n* Patients with significant neurological motor deficits of the upper extremities, and\u002For speech deficits, which would preclude them from performing the while awake intra-operative tasks at the discretion of the principal investigator (PI)\n* Patients who have impaired vision and\u002For hearing and whose performance could affect the study will be excluded at the discretion of the PI","ALL","18 Years",{"count":19,"type":20},75,"ESTIMATED","INTERVENTIONAL",[23],"NA","This pilot clinical trial studies how well electrocorticography works in mapping functional brain areas during surgery in patients with brain tumors. Using a larger than the standard mapping grid currently used during brain tumor surgery or a high-definition grid for electrocorticogram brain mapping may help doctors to better identify which areas of the brain are active during specific limb movement and speech during surgery in patients with brain tumors.",[26,27,28],"Brain Neoplasm","Metastatic Malignant Neoplasm in the Brain","Recurrent Brain Neoplasm","RECRUITING","2026-05-18",{"date":32,"type":33},"2026-05-20","ACTUAL",{"date":35,"type":33},"2016-07-22",{"date":37,"type":20},"2028-01-01",{"name":39,"class":40},"M.D. Anderson Cancer Center","OTHER",1,{"id":43,"slug":44,"hasResults":11,"nctId":45,"briefTitle":46,"officialTitle":46,"acronym":4,"eligibilityCriteria":47,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":48,"targetDuration":4,"studyType":50,"phases":4,"briefSummary":51,"conditions":52,"keywords":4,"overallStatus":55,"whyStopped":4,"lastUpdateSubmitDate":56,"lastUpdatePostDateStruct":57,"startDateStruct":59,"completionDateStruct":61,"leadSponsor":63,"locationsCount":41},"100564527","use-of-shear-wave-elastography-for-intraoperative-brain-and-tumor-stiffness-measurements-100564527","NCT06630338","Use of Shear Wave Elastography for Intraoperative Brain and Tumor Stiffness Measurements","Inclusion Criteria:\n\n* Patients must be at least 18 years old.\n* Patients must have planned surgery for resection of a newly diagnosed or recurrent brain tumors.\n* Patients with tumors located in the brain cortex or superficial white matter in which introduction of the ultrasound probe is straightforward and does not pose a risk for intraoperative complications.\n* Patients must have a Karnofsky performance status ≥ 60%.\n* Patient or legally authorized representative (LAR) willing to provide written informed consent.\n\nExclusion Criteria:\n\n* Patients with deep-seated brain tumors in which introduction of the ultrasound probe poses an increased risk.\n* Patients with a history of any brain infections.\n* Patients with implanted devices.\n* Patients with any other neurological\u002Fneurosurgical disease that could affect tissue stiffness.\n* Patients with any other structural brain defect that could affect tissue stiffness.",{"count":49,"type":20},30,"OBSERVATIONAL","This study investigates the role of intraoperative shear wave elastography ultrasound (ISWEU) in identifying healthy brain and tumor tissue stiffness differences. This data may be used to guide tumor resection in future patients.",[53,54,26,28],"Brain Tumor","Recurrent Brain Tumor","NOT_YET_RECRUITING","2026-03-23",{"date":58,"type":33},"2026-03-27",{"date":60,"type":20},"2026-06-01",{"date":62,"type":20},"2033-06-28",{"name":64,"class":40},"Mayo Clinic"]