[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"reflux-esophagitis\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:reflux-esophagitis":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,42,65],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":4,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":30,"lastUpdatePostDateStruct":31,"startDateStruct":34,"completionDateStruct":36,"leadSponsor":38,"locationsCount":41},"100573071","preliminary-efficacy-analysis-of-c-single-flap-plasty-reconstruction-after-laparoscopic-proximal-gastrectomy-100573071",false,"NCT06741501","Preliminary Efficacy Analysis of \"C\" Single Flap Plasty Reconstruction After Laparoscopic Proximal Gastrectomy","Laparoscopic Proximal Gastrectomy with \"C\" Single Flap Plasty Reconstruction for Upper-Third Gastric Cancer: a Randomized Clinical Trial.","Inclusion Criteria:\n\n1. Age between 18-80 years old, male or female;\n2. Pathological diagnosis of preoperative endoscopic biopsy: the tumor is located in the upper 1\u002F3 of the stomach (including the esophagogastric junction), and the clinical staging of gastric cancer： Ia and Ib (T1N0M0, T1N1M0, and T2N0M0) according to the eighth edition of the AJCC ;\n3. No distant metastasis was observed on preoperative chest radiograph, abdominal ultrasound, or upper abdominal CT;\n4. ASA grade 1-3;\n5. Patients without contraindications to surgery;\n6. Patients and their families voluntarily signed the informed consent form and participated in the study;\n\nExclusion Criteria:\n\n1. Patients diagnosed with primary tumors or distant metastasis;\n2. Patients whose tumor is located in the greater curvature side of the stomach;\n3. Patients with coagulation dysfunction that could not be corrected;\n4. Patients who were diagnosed with viral hepatitis and cirrhosis;\n5. Patients who were diagnosed with diabetes mellitus, uncontrolled or controlled with insulin;\n6. Patients with organ failure such as heart, lung, liver, brain, and kidney failure;\n7. Patients with ascites or cachexia preoperatively in poor general conditions;\n8. Patients diagnosed with immunodeficiency, immunosuppression, or autoimmune diseases (such as allogeneic bone marrow transplant, immunosuppressive drugs, SLE, etc.).\n9. Patients refusing to sign the informed consent of the study;","ALL","18 Years","80 Years",{"count":20,"type":21},50,"ESTIMATED","INTERVENTIONAL",[24],"NA","The incidence of proximal gastric cancer has increased significantly in recent years. This may be due to weight gain, alcohol consumption, gastroesophageal reflux disease (GERD), and precancerous lesions. With a deeper understanding of the pattern of lymph node metastasis and the emergence of anti-reflux procedures, proximal gastrectomy has gradually received clinical attention. For early-stage upper gastric cancer and esophagogastric combination cancer cases that are expected to have a good prognosis, the ideal surgical procedure should be to preserve the distal stomach to improve the quality of life and to choose a reasonable digestive tract reconstruction method to prevent reflux. The anti-reflux effect of various proximal gastrectomy digestive tract reconstruction methods and the advantages and disadvantages of various surgical procedures are controversial, and the recognized ideal reconstruction method has not yet been established. Therefore, we propose a reconstruction called the \"C\" Single Flap Plasty Reconstruction. This study aimed to investigate the efficacy and safety of proximal gastrectomy combined with \"C\" Single Flap Plasty Reconstruction in the treatment of gastric cancer.",[27,28],"Gastric Cancer","Reflux Esophagitis","NOT_YET_RECRUITING","2024-12-17",{"date":32,"type":33},"2024-12-19","ACTUAL",{"date":35,"type":21},"2025-01-01",{"date":37,"type":21},"2025-06-01",{"name":39,"class":40},"Daorong Wang","OTHER",1,{"id":43,"slug":44,"hasResults":11,"nctId":45,"briefTitle":46,"officialTitle":47,"acronym":4,"eligibilityCriteria":48,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":49,"enrollmentInfo":50,"targetDuration":4,"studyType":22,"phases":52,"briefSummary":53,"conditions":54,"keywords":4,"overallStatus":55,"whyStopped":4,"lastUpdateSubmitDate":56,"lastUpdatePostDateStruct":57,"startDateStruct":59,"completionDateStruct":61,"leadSponsor":63,"locationsCount":41},"100552598","preliminary-efficacy-analysis-of--double-tract-reconstruction-after-laparoscopic-proximal-gastrectomy-100552598","NCT06475170","Preliminary Efficacy Analysis of 'λ+α' Double-Tract Reconstruction After Laparoscopic Proximal Gastrectomy","Laparoscopic Proximal Gastrectomy With 'λ+α' Double-Tract Reconstruction for Upper-Third Early Gastric Cancer: A Randomized Clinical Trial.","Inclusion Criteria:\n\nAge between 18-75 years old, male or female; Pathological diagnosis of preoperative endoscopic biopsy: the tumor is located in the upper 1\u002F3 of the stomach (including the esophagogastric junction), and the clinical staging of gastric cancer： Ia and Ib (T1N0M0, T1N1M0, and T2N0M0) (14) according to the eighth edition of the AJCC (15); No distant metastasis was observed on preoperative chest radiograph, abdominal ultrasound, or upper abdominal CT; ASA grade 1-3; Patients without contraindications to surgery; Patients and their families voluntarily signed the informed consent form and participated in the study;\n\nExclusion Criteria:\n\nPatients diagnosed with primary tumors or distant metastasis; Patients whose tumor is located in the greater curvature side of the stomach; Patients with coagulation dysfunction that could not be corrected; Patients who were diagnosed with viral hepatitis and cirrhosis; Patients who were diagnosed with diabetes mellitus, uncontrolled or controlled with insulin; Patients with organ failure such as heart, lung, liver, brain, and kidney failure; Patients with ascites or cachexia preoperatively in poor general conditions; Patients diagnosed with immunodeficiency, immunosuppression, or autoimmune diseases (such as allogeneic bone marrow transplant, immunosuppressive drugs, SLE, etc.).\n\nPatients refusing to sign the informed consent of the study;","75 Years",{"count":51,"type":21},60,[24],"The incidence of proximal gastric cancer has increased significantly in recent years. This may be due to weight gain, alcohol consumption, gastroesophageal reflux disease (GERD), and precancerous lesions. With a deeper understanding of the pattern of lymph node metastasis and the emergence of anti-reflux procedures, proximal gastrectomy has gradually received clinical attention. For early-stage upper gastric cancer and esophagogastric combination cancer cases that are expected to have a good prognosis, the ideal surgical procedure should be to preserve the distal stomach to improve the quality of life and to choose a reasonable digestive tract reconstruction method to prevent reflux. The anti-reflux effect of various proximal gastrectomy digestive tract reconstruction methods and the advantages and disadvantages of various surgical procedures are controversial, and the recognized ideal reconstruction method has not yet been established. Therefore, based on the stomach's anatomical features and the intercalated jejunum's anti-reflux mechanism, we propose a true dual-channel anastomosis for GI reconstruction, i.e., the \"λ+α dual-channel anastomosis\". This study aimed to investigate the efficacy and safety of proximal gastrectomy combined with \"λ+α double-channel anastomosis\" in the treatment of early gastric cancer.",[27,28],"RECRUITING","2024-08-13",{"date":58,"type":33},"2024-08-15",{"date":60,"type":33},"2024-08-01",{"date":62,"type":21},"2025-12-31",{"name":64,"class":40},"Northern Jiangsu People's Hospital",{"id":66,"slug":67,"hasResults":11,"nctId":68,"briefTitle":69,"officialTitle":70,"acronym":4,"eligibilityCriteria":71,"healthyVolunteers":11,"sex":16,"minAge":72,"maxAge":49,"enrollmentInfo":73,"targetDuration":4,"studyType":22,"phases":75,"briefSummary":76,"conditions":77,"keywords":4,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":82,"lastUpdatePostDateStruct":83,"startDateStruct":85,"completionDateStruct":87,"leadSponsor":89,"locationsCount":4},"100520873","protocol-for-comparing-the-efficacy-of-three-reconstruction-methods-of-the-digestive-tract-after-proximal-gastrectomy-100520873","NCT06062225","Protocol for Comparing the Efficacy of Three Reconstruction Methods of the Digestive Tract After Proximal Gastrectomy","Protocol for Comparing the Efficacy of Three Reconstruction Methods of the Digestive Tract (Kamikawa Versus Single-Tract Jejunal Interposition Versus SOFY Reconstruction) After Proximal Gastrectomy","Inclusion Criteria:\n\n* Age between 20-75 years old, male or female;\n* Pathological diagnosis of preoperative endoscopic biopsy: the tumor is located in the upper 1\u002F3 of the stomach (including the esophagogastric junction), and the clinical staging of gastric cancer： Ia and Ib (T1N0M0, T1N1M0, and T2N0M0) (14) according to the eighth edition of the AJCC (15);\n* No distant metastasis observed on preoperative chest radiograph, abdominal ultrasound or upper abdominal CT;\n* ASA grade 1-3;\n* Patients without contraindications to surgery;\n* Patients and their families voluntarily signing the informed consent form and participating in the study;\n\nExclusion Criteria:\n\n* Patients diagnosed with primary tumors or distant metastasis;\n* Patients whose tumor is located in the greater curvature side of the stomach;\n* Patients with coagulation dysfunction which could not be corrected;\n* Patients who were diagnosed with viral hepatitis and cirrhosis;\n* Patients who were diagnosed with diabetes mellitus, uncontrolled or controlled with insulin;\n* Patients with organ failure such as heart, lung, liver, brain, kidney failure;\n* Patients with ascites or cachexia preoperatively in poor general conditions;\n* Patients diagnosed with immunodeficiency, immunosuppression or autoimmune diseases (such as allogeneic bone marrow transplant, immunosuppressive drugs, SLE, etc.).\n* Patients refusing to sign the informed consent of the study;","20 Years",{"count":74,"type":21},180,[24],"The efficacy of three different reconstruction methods after proximal gastrectomy will be investigated in this study through a prospective, multicenter, randomized controlled trial.",[78,79,80,28,81],"Proximal Gastric Adenocarcinoma","Gastrectomy","Anastomosis","Postoperative Complications","2023-10-03",{"date":84,"type":33},"2023-10-05",{"date":86,"type":21},"2023-10",{"date":88,"type":21},"2026-10",{"name":90,"class":40},"Changzhi People's Hospital Affiliated to Changzhi Medical College"]