[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"refractory-melasma\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:refractory-melasma":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":4,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":29,"lastUpdatePostDateStruct":30,"startDateStruct":33,"completionDateStruct":35,"leadSponsor":37,"locationsCount":5},"100556275","fractional-erbium-yag-laser-vs-intradermal-and-systemic-tranexamic-acid-100556275",false,"NCT06522984","Fractional Erbium YAG Laser vs Intradermal and Systemic Tranexamic Acid","Fractional Erbium YAG Laser vs Intradermal and Systemic Tranexamic Acid in Combination With Topical Hydroquinone for Refractory Melasma","Inclusion Criteria:\n\n\\- Patients of both sexes with melasma.\n\nExclusion Criteria:\n\n* Pregnancy\n* Lactation\n* Administration of oral contraceptive pills or any phototoxic drug within 1 month prior to study\n* Patients with a history of thrombosis, abnormal bleeding profile, known hypersensitivity to TA or HQ, and endocrinal disease.","ALL","18 Years","40 Years",{"count":20,"type":21},45,"ESTIMATED","INTERVENTIONAL",[24],"NA","Melasma is a common acquired disorder of hyperpigmentaion caused by increased melanin production by melanocytes.\n\nMelasma is a name derived from the Greek word melas meaning black.It is characterized by the appearance of brownish or grayish symmetrical patches on sun-exposed skin, most commonly on the face. Compared to men, women are more likely to be affected.",[27],"Refractory Melasma","RECRUITING","2024-07-23",{"date":31,"type":32},"2024-07-26","ACTUAL",{"date":34,"type":32},"2024-06-01",{"date":36,"type":21},"2025-06-10",{"name":38,"class":39},"Egymedicalpedia","INDUSTRY"]