[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"regional-anaesthesia\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:regional-anaesthesia":30},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,21,0,[8,49,78,104,134,157,178,200,221,249,277,305,335,353,376,401,429,455,480,503,532],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":32,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":38,"lastUpdatePostDateStruct":39,"startDateStruct":42,"completionDateStruct":44,"leadSponsor":46,"locationsCount":4},"100611303","transversalis-fascia-plane-block-versus-surgical-wound-infiltration-for-postoperative-analgesia-in-open-inguinal-hernia-repair-100611303",false,"NCT07238829","Transversalis Fascia Plane Block Versus Surgical Wound Infiltration for Postoperative Analgesia in Open Inguinal Hernia Repair","Analgesic Efficacy of Ultrasound-Guided Transversalis Fascia Plane Block Versus Surgical Wound Infiltration After Open Inguinal Hernia Surgery: A Randomized Controlled Trial","TFPB-WIN","Inclusion Criteria:\n\n* Age ≥ 18 years\n* Scheduled for elective unilateral open inguinal hernia repair\n* Planned anesthesia: spinal anesthesia\n* American Society of Anesthesiologists (ASA) physical status I-II\n* Able to understand the study procedures and provide written informed consent\n\nExclusion Criteria:\n\n* Body mass index (BMI) \\> 35 kg\u002Fm²\n* Known hypersensitivity to local anesthetics used in the study (e.g., bupivacaine) or to analgesic medications\n* Coagulopathy\n* Infection or hematoma at the planned block site\n* Significant systemic disease (such as chronic kidney disease, hepatic failure, chronic obstructive pulmonary disease, etc.)\n* History of chronic pain or long-term analgesic use\n* Inability to use the patient-controlled analgesia system\n* Presence of psychiatric disorders\n* Refusal to participate in the study.\n* Cases with a surgical duration shorter than 30 minutes or longer than 180 minutes were excluded.","ALL","18 Years","80 Years",{"count":21,"type":22},104,"ESTIMATED","INTERVENTIONAL",[25],"NA","The purpose of this clinical trial is to evaluate whether two different analgesic techniques - ultrasound-guided Transversalis Fascia Plane Block (TFPB) and surgical wound infiltration - can improve postoperative pain control in adult patients undergoing open inguinal hernia repair.\n\nThe key questions that this study aims to answer are:\n\nDoes TFPB reduce total intravenous opioid consumption within the first 24 postoperative hours compared with wound infiltration?\n\nDoes TFPB improve postoperative pain scores at rest and during movement compared with wound infiltration?\n\nDoes TFPB improve patient satisfaction, reduce the need for rescue analgesics, and enhance overall postoperative recovery quality?\n\nIf there is a comparison group:\n\nThe investigators will compare the effects of TFPB with wound infiltration to determine whether either technique provides superior postoperative analgesia and reduces opioid requirements.\n\nParticipants will be asked to:\n\nUndergo open inguinal hernia repair under spinal anesthesia.\n\nBe randomly assigned to one of two groups:\n\nTFPB Group: Receive an ultrasound-guided transversalis fascia plane block with local anesthetic.\n\nWound Infiltration Group: Receive local anesthetic infiltration performed by the surgeon along the incision line.\n\nPostoperatively:\n\nReport pain scores at defined intervals.\n\nReceive standardized IV analgesia with documentation of opioid consumption.\n\nAllow assessment of rescue analgesic requirement.\n\nBe monitored for adverse events and recovery outcomes.",[28,29,30,31],"Inguinal Hernia Unilateral","Postoperative Pain Management","Regional Anaesthesia","Transversalis Fascia Plane Block",[33,34,35,36],"transversalis fascia plane block","regional anaesthesia","inguinal hernia","analgesia","NOT_YET_RECRUITING","2026-06-20",{"date":40,"type":41},"2026-06-25","ACTUAL",{"date":43,"type":22},"2027-01-01",{"date":45,"type":22},"2027-04-01",{"name":47,"class":48},"Ondokuz Mayıs University","OTHER",{"id":50,"slug":51,"hasResults":11,"nctId":52,"briefTitle":53,"officialTitle":54,"acronym":4,"eligibilityCriteria":55,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":56,"enrollmentInfo":57,"targetDuration":4,"studyType":23,"phases":59,"briefSummary":60,"conditions":61,"keywords":66,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":69,"lastUpdatePostDateStruct":70,"startDateStruct":72,"completionDateStruct":74,"leadSponsor":76,"locationsCount":4},"100641947","intertransverse-process-block-versus-m-tapa-block-after-laparoscopic-cholecystectomy-100641947","NCT07589491","Intertransverse Process Block Versus M-TAPA Block After Laparoscopic Cholecystectomy","Intertransverse Process Block Versus M-TAPA Block After Laparoscopic Cholecystectomy: A Prospective Randomized Controlled Trial","Inclusion Criteria:\n\n* Patients aged 18-65 years\n* ASA physical status I-III\n* Scheduled for elective laparoscopic sleeve gastrectomy\n* Body mass index (BMI) 18-35 kg\u002Fm²\n* Ability to understand and use the patient-controlled analgesia (PCA) device\n* Ability to provide written informed consent\n\nExclusion Criteria:\n\n* Refusal to participate\n* Allergy to local anesthetics\n* Infection at the injection site\n* Coagulopathy or ongoing anticoagulant therapy\n* Chronic opioid use or opioid dependence\n* Severe hepatic or renal insufficiency\n* Pregnancy or breastfeeding\n* Cognitive impairment or inability to communicate pain scores\n* Body mass index (BMI) \\>35 kg\u002Fm²","65 Years",{"count":58,"type":22},60,[25],"This randomized clinical trial aims to evaluate and compare the analgesic efficacy of the Intertransverse Process Block (ITPB) and the Modified Thoracoabdominal Nerve Block through Perichondrial Approach (M-TAPA) in patients undergoing laparoscopic cholecystectomy. The primary outcome is the Visual Analog Scale (VAS) score within the first 24 hours after surgery. Secondary outcomes include total opioid consumption, requirement for rescue analgesia, block- related complications and adverse effects (hematoma, pneumothorax, local anesthetic systemic complications, vascular puncture, and infection), patient satisfaction assessed using a Likert scale, quality of recovery assessed using the QoR-15 questionnaire, and incidence of postoperative nausea and vomiting.",[62,63,64,65,30],"Intertransverse Process Block","Mtapa Block","Laparoscopic Cholecystectomy","Postoperative Pain",[67,68],"M-TAPA","ITP","2026-06-15",{"date":71,"type":41},"2026-06-16",{"date":73,"type":22},"2026-11-15",{"date":75,"type":22},"2027-10-30",{"name":77,"class":48},"Antalya City Hospital",{"id":79,"slug":80,"hasResults":11,"nctId":81,"briefTitle":82,"officialTitle":83,"acronym":84,"eligibilityCriteria":85,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":86,"targetDuration":4,"studyType":23,"phases":88,"briefSummary":89,"conditions":90,"keywords":4,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":94,"lastUpdatePostDateStruct":95,"startDateStruct":97,"completionDateStruct":99,"leadSponsor":101,"locationsCount":4},"100643126","comparison-of-90-and-120-arm-positions-in-costoclavicular-block-100643126","NCT07586670","Comparison of 90° and 120° Arm Positions in Costoclavicular Block","Effect of Arm Abduction Degree ( 90° vs. 120° ) on Block Onset Time and Block Success in Costoclavicular Brachial Plexus Block in Patients Undergoing Hand, Wrist and Forearm Surgery: A Prospective Randomized Controlled Trial","COSTO-RCT","Inclusion Criteria:\n\n* Patients aged between 18 and 80 years.\n* Patients scheduled for elective upper extremity surgery (hand, wrist, forearm).\n* Patients classified as ASA I-III.\n* Patients who provide informed consent after being informed about the study.\n\nExclusion Criteria:\n\n* History of previous surgery, scar tissue, tumor, or trauma that may alter brachial plexus anatomy.\n* Presence of infection, hematoma, severe edema, burn, or open wound at the block application site.\n* Known allergy to local anesthetics or other medications used in the study.\n* Coagulopathy, use of anticoagulants, or platelet count \\\u003C 100,000\u002Fmm³.\n* History of peripheral neuropathy, neurological deficit, cervical radiculopathy, or CRPS.\n* Pregnancy or breastfeeding.\n* Patients with BMI \\\u003C 18 kg\u002Fm².\n* Patients with BMI \\> 35 kg\u002Fm².\n* Severe cardiac, pulmonary, renal, or hepatic failure.\n* Mental retardation, communication difficulties, or lack of cooperation.\n* Deformity, amputation, or large mass in the surgical extremity that may interfere with sensorimotor assessment.\n* Preoperative significant sensory loss, motor weakness, or signs of neurological disease.\n* Severe anemia (Hb \\\u003C 9 g\u002FdL) or polycythemia (Hb \\> 18 g\u002FdL).\n* Psychiatric disorders, substance abuse, or any condition that may interfere with study compliance.",{"count":87,"type":22},106,[25],"The costoclavicular approach of the infraclavicular brachial plexus block is widely used for upper extremity surgeries due to its reliable anatomy and high success rates. Patient positioning, particularly the degree of arm abduction, may influence the spread of local anesthetic and the characteristics of the block. However, the optimal arm abduction angle during this procedure remains unclear.\n\nThis prospective randomized controlled trial aims to investigate the effect of two different arm abduction angles (90° and 120°) on block onset time and block success in patients undergoing hand, wrist, and forearm surgery under ultrasound-guided costoclavicular brachial plexus block.\n\nPatients will be randomly assigned to one of two groups according to the degree of arm abduction. The primary outcome is block onset time. Secondary outcomes include block success, sensory and motor block characteristics, perfusion index changes, hemodynamic parameters, readiness for surgery at 15 and 20 minutes, block performance time, need for additional anesthesia, postoperative neurological evaluation at 4 and 24 hours, complications, and patient satisfaction.\n\nThe findings of this study are expected to provide evidence on optimal patient positioning to improve the effectiveness and reliability of ultrasound-guided costoclavicular brachial plexus block.",[91,92,93,30],"Perfusion Index","Upper Extremity Surgery","Brachial Plexus Block","2026-06-06",{"date":96,"type":41},"2026-06-09",{"date":98,"type":22},"2026-05-15",{"date":100,"type":22},"2026-08-27",{"name":102,"class":103},"Ankara Etlik City Hospital","OTHER_GOV",{"id":105,"slug":106,"hasResults":11,"nctId":107,"briefTitle":108,"officialTitle":109,"acronym":4,"eligibilityCriteria":110,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":111,"targetDuration":4,"studyType":113,"phases":4,"briefSummary":114,"conditions":115,"keywords":118,"overallStatus":124,"whyStopped":4,"lastUpdateSubmitDate":125,"lastUpdatePostDateStruct":126,"startDateStruct":128,"completionDateStruct":129,"leadSponsor":131,"locationsCount":133},"100638019","fascial-plane-blocks-in-cardiac-surgery-100638019","NCT07622823","Fascial Plane Blocks In Cardiac Surgery","The Effect Of Combined Rectus-Intercostal Fascial Plane Block Or Rectus Sheatf Block With A Pectoral-Intercostal Fascial Plane Block In Cardiac Surgery On Postoperative Opioid Consumption, Quality Of Recovery, And Chronic Pain: A Prospective, Observational Study","Inclusion Criteria:\n\n* elective cardiac surgery planned\n* over 18 years, adult\n* American Society of Anaesthesiology (ASA) score I-III\n\nExclusion Criteria:\n\n* under 18 years of age,\n* ASA IV and above,\n* contraindications for the block application\n* history of cardiac surgery,\n* reoperated due to surgery-related complications after emergency surgery or postoperative elective surgery,\n* off-pump cardiac surgery or minimally invasive cardiac surgery\n* unable to be extubated in the intensive care unit at 24 hours postoperatively\n* history of chronic pain treatment\n* chronic alcoholism and substance abuse\n* declining to give written informed consent",{"count":112,"type":22},90,"OBSERVATIONAL","The aim of the present study is to evaluate the effects of the recto-intercostal fascial plane block (RIFPB) or the rectus sheath block (RSB) combined with the pectoral-intercostal fascial plane block (PIFPB) on postoperative analgesia in patients undergoing cardiac surgery.",[116,30,117],"Cardiovascular Surgery","Postoperative Analgesia",[119,120,121,122,123],"cardiovascular surgery","pectoral-intercostal fascial plane block","recto-intercostal fascial plane block","rectus sheath block","postoperative analgesia","RECRUITING","2026-06-01",{"date":127,"type":41},"2026-06-03",{"date":125,"type":41},{"date":130,"type":22},"2026-12-01",{"name":132,"class":48},"Antalya Health Sciences University",1,{"id":135,"slug":136,"hasResults":11,"nctId":137,"briefTitle":138,"officialTitle":139,"acronym":4,"eligibilityCriteria":140,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":56,"enrollmentInfo":141,"targetDuration":4,"studyType":23,"phases":142,"briefSummary":143,"conditions":144,"keywords":146,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":150,"lastUpdatePostDateStruct":151,"startDateStruct":152,"completionDateStruct":154,"leadSponsor":156,"locationsCount":4},"100639163","transversalis-fascia-plane-block-versus-m-tapa-block-after-laparoscopic-inguinal-hernia-repair-100639163","NCT07619053","Transversalis Fascia Plane Block Versus M-TAPA Block After Laparoscopic Inguinal Hernia Repair","Transversalis Fascia Plane Block Versus Modified Thoracoabdominal Nerve Block Through Perichondrial Approach (M-TAPA) for Postoperative Analgesia After Laparoscopic Inguinal Hernia Repair: A Prospective Randomized Controlled Trial","Inclusion Criteria:\n\n* Patients aged 18-65 years\n* ASA physical status I-III\n* Scheduled for elective laparoscopic inguinal hernia repair\n* Body mass index (BMI) 18-35 kg\u002Fm²\n* Ability to understand and use the patient-controlled analgesia (PCA) device\n* Ability to provide written informed consent\n\nExclusion Criteria:\n\n* Refusal to participate\n* Allergy to local anesthetics\n* Infection at the injection site\n* Coagulopathy or ongoing anticoagulant therapy\n* Chronic opioid use or opioid dependence\n* Severe hepatic or renal insufficiency\n* Pregnancy or breastfeeding\n* Cognitive impairment or inability to communicate pain scores\n* Body mass index (BMI) \\>35 kg\u002Fm²",{"count":58,"type":22},[25],"This randomized clinical trial aims to evaluate and compare the analgesic efficacy of the Transversalis Fascia Plane Block (TFPB) and the Modified Thoracoabdominal Nerve Block through Perichondrial Approach (M-TAPA) in patients undergoing laparoscopic inguinal hernia repair. The primary outcome is the Visual Analog Scale (VAS) score within the first 24 hours after surgery. Secondary outcomes include total opioid consumption, requirement for rescue analgesia, block-related complications and adverse effects (hematoma, local anesthetic systemic complications, vascular puncture, and infection), patient satisfaction assessed using a Likert scale, quality of recovery assessed using the QoR-15 questionnaire, and incidence of postoperative nausea and vomiting.",[31,63,30,65,145],"Laparoscopic Inguinal Hernia Repair",[147,67,148,149],"TFPB","İNGUİNAL HERNİA","TRANSVERSALİS FASCİA PLANE BLOCK","2026-05-26",{"date":125,"type":41},{"date":153,"type":22},"2026-11-30",{"date":155,"type":22},"2027-07-30",{"name":77,"class":48},{"id":158,"slug":159,"hasResults":11,"nctId":160,"briefTitle":161,"officialTitle":162,"acronym":4,"eligibilityCriteria":163,"healthyVolunteers":11,"sex":164,"minAge":18,"maxAge":56,"enrollmentInfo":165,"targetDuration":4,"studyType":23,"phases":166,"briefSummary":167,"conditions":168,"keywords":170,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":98,"lastUpdatePostDateStruct":171,"startDateStruct":173,"completionDateStruct":175,"leadSponsor":177,"locationsCount":4},"100640445","intertransverse-process-block-versus-m-tapa-block-after-laparoscopic-hysterectomy-100640445","NCT07599787","Intertransverse Process Block Versus M-TAPA Block After Laparoscopic Hysterectomy","Intertransverse Process Block Versus M-TAPA Block After Laparoscopic Hysterectomy: A Prospective Randomized Controlled Trial","Inclusion Criteria:\n\n* Patients aged 18-65 years\n* ASA physical status I-III\n* Scheduled for elective laparoscopic hysterectomy\n* Body mass index (BMI) 18-35 kg\u002Fm²\n* Ability to understand and use the patient-controlled analgesia (PCA) device\n* Ability to provide written informed consent\n\nExclusion Criteria:\n\n* Refusal to participate\n* Allergy to local anesthetics\n* Infection at the injection site\n* Coagulopathy or ongoing anticoagulant therapy\n* Chronic opioid use or opioid dependence\n* Severe hepatic or renal insufficiency\n* Pregnancy or breastfeeding\n* Cognitive impairment or inability to communicate pain scores\n* Body mass index (BMI) \\>35 kg\u002Fm²","FEMALE",{"count":58,"type":22},[25],"This randomized clinical trial aims to evaluate and compare the analgesicefficacy of the Intertransverse Process Block (ITPB) and the Modified Thoracoabdominal Nerve Block through Perichondrial Approach (M-TAPA) in patients undergoing laparoscopic hysterectomy. The primary outcome is the Visual Analog Scale (VAS) score within the first 24 hours after surgery. Secondary outcomes include total opioid consumption, requirement for rescue analgesia, block- related complications and adverse effects (hematoma, pneumothorax, local anesthetic systemic complications, vascular puncture, and infection), patient satisfaction assessed using a Likert scale, quality of recovery assessed using the QoR-15 questionnaire, and incidence of postoperative nausea and vomiting.",[62,63,169,65,30],"Laparoscopic Hysterectomy",[67,68],{"date":172,"type":41},"2026-05-20",{"date":174,"type":22},"2026-11-18",{"date":176,"type":22},"2027-11-30",{"name":77,"class":48},{"id":179,"slug":180,"hasResults":11,"nctId":181,"briefTitle":182,"officialTitle":183,"acronym":4,"eligibilityCriteria":184,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":56,"enrollmentInfo":185,"targetDuration":4,"studyType":23,"phases":186,"briefSummary":187,"conditions":188,"keywords":191,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":193,"lastUpdatePostDateStruct":194,"startDateStruct":195,"completionDateStruct":197,"leadSponsor":199,"locationsCount":4},"100637643","intertransverse-process-block-versus-external-oblique-intercostal-plane-block-after-laparoscopic-sleeve-gastrectomy-100637643","NCT07591116","Intertransverse Process Block Versus External Oblique Intercostal Plane Block After Laparoscopic Sleeve Gastrectomy","Intertransverse Process Block Versus External Oblique Intercostal Plane Block for Postoperative Analgesia After Laparoscopic Sleeve Gastrectomy: A Prospective Randomized Controlled Trial","Inclusion Criteria:\n\n* Patients aged 18-65 years\n* ASA physical status I-III\n* Scheduled for elective laparoscopic sleeve gastrectomy\n* Body mass index (BMI) \\>35 kg\u002Fm²\n* Ability to understand and use the patient-controlled analgesia (PCA) device\n* Ability to provide written informed consent\n\nExclusion Criteria:\n\n* Refusal to participate\n* Allergy to local anesthetics\n* Infection at the injection site\n* Coagulopathy or ongoing anticoagulant therapy\n* Chronic opioid use or opioid dependence\n* Severe hepatic or renal insufficiency\n* Pregnancy or breastfeeding\n* Cognitive impairment or inability to communicate pain scores\n* Body mass index (BMI) \\>35 kg\u002Fm²",{"count":58,"type":22},[25],"This randomized clinical trial aims to evaluate and compare the analgesic efficacy of the Intertransverse Process Block (ITPB) and the Subcostal External Oblique Intercostal Plane Block (EOIPB) in patients undergoing laparoscopic sleeve gastrectomy. The primary outcome is the Visual Analog Scale (VAS) score within the first 24 hours after surgery. Secondary outcomes include total opioid consumption, requirement for rescue analgesia, block-related complications and adverse effects (hematoma, pneumothorax, local anesthetic systemic complications, vascular puncture, and infection), patient satisfaction assessed using a Likert scale, quality of recovery assessed using the QoR-15 questionnaire, and incidence of postoperative nausea and vomiting.",[62,189,190,30,65],"External Oblique Intercostal Plane Block","Sleeve Gastrectomy",[68,192],"EOIPB","2026-05-09",{"date":98,"type":41},{"date":196,"type":22},"2026-12-15",{"date":198,"type":22},"2027-12-30",{"name":77,"class":48},{"id":201,"slug":202,"hasResults":11,"nctId":203,"briefTitle":204,"officialTitle":205,"acronym":4,"eligibilityCriteria":184,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":56,"enrollmentInfo":206,"targetDuration":4,"studyType":23,"phases":207,"briefSummary":208,"conditions":209,"keywords":211,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":193,"lastUpdatePostDateStruct":215,"startDateStruct":216,"completionDateStruct":218,"leadSponsor":220,"locationsCount":133},"100638217","intertransverse-process-block-versus-subcostal-transversus-abdominis-plane-block-after-laparoscopic-sleeve-gastrectomy-100638217","NCT07591129","Intertransverse Process Block Versus Subcostal Transversus Abdominis Plane Block After Laparoscopic Sleeve Gastrectomy","Intertransverse Process Block Versus Subcostal Transversus Abdominis Plane Block for Postoperative Analgesia After Laparoscopic Sleeve Gastrectomy: A Prospective Randomized Controlled Trial",{"count":58,"type":22},[25],"This randomized clinical trial aims to evaluate and compare the analgesic efficacy of the Intertransverse Process Block (ITPB) and the Subcostal Transversus Abdominis Plane Block (TAPB) in patients undergoing laparoscopic sleeve gastrectomy. The primary outcome is the Visual Analog Scale (VAS) score within the first 24 hours after surgery. Secondary outcomes include total opioid consumption, requirement for rescue analgesia, block-related complications and adverse effects (hematoma, pneumothorax, local anesthetic systemic complications, vascular puncture, and infection), patient satisfaction assessed using a Likert scale, quality of recovery assessed using the QoR-15 questionnaire, and incidence of postoperative nausea and vomiting.",[62,210,190,65,30],"Subcostal Transverse Abdominis Plane Block",[68,212,213,214],"TAP","PAİN","SLEEVE GASTRECTOMİ",{"date":98,"type":41},{"date":217,"type":22},"2026-12-30",{"date":219,"type":22},"2028-05-30",{"name":77,"class":48},{"id":222,"slug":223,"hasResults":11,"nctId":224,"briefTitle":225,"officialTitle":226,"acronym":4,"eligibilityCriteria":227,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":228,"enrollmentInfo":229,"targetDuration":4,"studyType":113,"phases":4,"briefSummary":231,"conditions":232,"keywords":236,"overallStatus":124,"whyStopped":4,"lastUpdateSubmitDate":240,"lastUpdatePostDateStruct":241,"startDateStruct":243,"completionDateStruct":245,"leadSponsor":247,"locationsCount":133},"100638881","the-impact-of-video-assisted-thoracic-surgery-and-regional-anaesthesia-on-postoperative-opioid-consumption-and-pain-scores-100638881","NCT07578545","The Impact of Video-assisted Thoracic Surgery and Regional Anaesthesia on Postoperative Opioid Consumption and Pain Scores","The Effect of Paravertebral Block, Intertransverse Block, and Erector Spinae Plane Block on Postoperative Opioid Consumption and Pain Scores in Video-assisted Thoracic Surgery: a Prospective Observational Study","Inclusion Criteria:\n\n* aged 18-75 years\n* American Society of Anaesthesiology (ASA) score I-III\n* body mass index (BMI) \\\u003C35kg\u002Fm2\n* scheduled for elective VATS\n\nExclusion Criteria:\n\n* ASA score ≥4\n* BMI ≥35 kg\u002Fm2\n* declining to give written informed consent\n* controendications for block application\n* inability to undergo block application\n* history neurological disease or peripheral nerve disease\n* history of chronic opioid use\n* history of severe liver or kidney failure\n* patients admitted to the intensive care unit postoperatively intubated","75 Years",{"count":230,"type":22},96,"This present study aims is to compare the effects of ultrasound-guided paravertebral block, intertransverse process block, and erector spinae plane block on postoperative opioid consumption, and pain scores in patients undergoing VATS.",[233,234,30,117,235],"Thoracic Surgery","Videoassisted Thoracoscopic Surgery,One-lung Ventilation","Pain Score",[237,34,123,238,239],"videoassisted thoracoscopic surgery","chronic pain","quality of recovery","2026-05-06",{"date":242,"type":41},"2026-05-11",{"date":244,"type":41},"2026-05-04",{"date":246,"type":22},"2026-11-04",{"name":248,"class":103},"Antalya Training and Research Hospital",{"id":250,"slug":251,"hasResults":11,"nctId":252,"briefTitle":253,"officialTitle":254,"acronym":4,"eligibilityCriteria":255,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":56,"enrollmentInfo":256,"targetDuration":4,"studyType":113,"phases":4,"briefSummary":258,"conditions":259,"keywords":265,"overallStatus":124,"whyStopped":4,"lastUpdateSubmitDate":240,"lastUpdatePostDateStruct":271,"startDateStruct":272,"completionDateStruct":274,"leadSponsor":276,"locationsCount":133},"100635509","the-effects-of-regional-anaesthesia-techniques-on-hemidiaphragm-paralysis-postoperative-recovery-quality-opioid-consumption-and-pain-scores-100635509","NCT07553611","The Effects of Regional Anaesthesia Techniques on Hemidiaphragm Paralysis, Postoperative Recovery Quality, Opioid Consumption, and Pain Scores","Comparion of the Effects of Ultrasound-guided Interscalene Block, Erector Spinae Plane Block, Costoclavicular Block, and Supraclavicular Block on Hemidiaphragm Paralysis, Postoperative Recovery Quality, Opioid Consumption, and Pain Scores in Patients Undergoing Arthroscopic Shoulder Surgery: a Prospective Observational Trial","Inclusion Criteria:\n\n* aged 18-65 years\n* American Society of Anaesthesiology (ASA) score I-III\n* body mass index (BMI) \\\u003C30kg\u002Fm2\n* scheduled for elective arthroscopic surgery\n\nExclusion Criteria:\n\n* ASA score ≥4\n* BMI ≥30 kg\u002Fm2\n* declining to give written informed consent\n* controendications for block application\n* history of mental or neurological disease, severe liver and\u002For kidney disease\n* history of moderate or severe pulmonary disease\n* abnormal preoperative chest X-ray findings\n* scheduled for emergency surgery",{"count":257,"type":22},88,"This study aims to evaluate the effects of ultrasound-guided interscalene, erector spinae plane, costoclavicular, and supraclavicular blocks on hemidiaphragmatic paralysis, postoperative recovery quality, opioid consumption, and pain scores.",[30,260,261,262,263,264],"Arthroscopic Shoulder Surgery","Hemidiaphragmatic Paralysis","Recovery Quality","Opioid Consumption","Postoperative Pain Score",[34,266,267,268,269,270],"arthroscopic shoulder surgery","hemidiaphragmatic paralysis","recovery quality","opioid consumption","postoperative pain score",{"date":242,"type":41},{"date":273,"type":41},"2026-04-21",{"date":275,"type":22},"2026-11-21",{"name":248,"class":103},{"id":278,"slug":279,"hasResults":11,"nctId":280,"briefTitle":281,"officialTitle":282,"acronym":4,"eligibilityCriteria":283,"healthyVolunteers":11,"sex":164,"minAge":18,"maxAge":228,"enrollmentInfo":284,"targetDuration":4,"studyType":23,"phases":286,"briefSummary":287,"conditions":288,"keywords":291,"overallStatus":124,"whyStopped":4,"lastUpdateSubmitDate":297,"lastUpdatePostDateStruct":298,"startDateStruct":299,"completionDateStruct":301,"leadSponsor":303,"locationsCount":133},"100621268","comparison-of-the-analgesic-efficacy-of-erector-spinae-plane-block-in-breast-conserving-surgery-versus-serratus-anterior-block-combined-with-additional-pecto-intercostal-ii-block-100621268","NCT07368413","Comparison of the Analgesic Efficacy of Erector Spinae Plane Block in Breast-Conserving Surgery Versus Serratus Anterior Block Combined With Additional Pecto-Intercostal II Block","Comparison of Analgesic Efficacy and Opioid Consumption of Erector Spinae Plane Block Versus Serratus Anterior Block With Additional Pecto-Intercostal II Block in Breast-Conserving Surgery","Inclusion Criteria:\n\n* Age between 18 and 75 years\n* ASA physical status I-III\n* No history of bleeding or coagulation disorders\n* Absence of neuropathy\n* Preoperative breast region NRS score \\\u003C 4\n\nExclusion Criteria:\n\n* systemic or regional infection\n* known allergy to local anesthetics\n* Unwillingness to participate in the study",{"count":285,"type":22},70,[25],"This prospective randomized study will compare the effects of Erector Spinae Plane Block (ESPB) and Serratus Anterior Plane Block combined with Pectoral Nerve Block Type II (SAPB + PECS II) on intraoperative analgesia and postoperative opioid consumption in patients undergoing breast cancer surgery. Seventy patients (ASA I-III, aged 18-75 years) will be randomized into two groups using the sealed envelope method. Ultrasound-guided blocks will be performed preoperatively by the same anesthesiologist, with Group 1 receiving ESPB and Group 2 receiving a combined SAPB + PECS II technique performed through a single skin puncture (single needle entry site) with sequential injections into the two target fascial planes. All patients will undergo surgery under general anesthesia and receive postoperative analgesia via morphine patient-controlled analgesia. Pain scores and total opioid consumption will be statistically analyzed, with p \\\u003C 0.05 considered significant.",[289,290,30],"Pain Management in Breast Surgery","Pain After Surgery",[292,293,30,294,295,296],"breast surgery","pain","Serratus Anterior Plane Block","Pectoral Nerve Block Type 2","Erector Spinae Plane Block","2026-04-20",{"date":273,"type":41},{"date":300,"type":41},"2026-04-10",{"date":302,"type":22},"2026-07-31",{"name":304,"class":103},"Kayseri City Hospital",{"id":306,"slug":307,"hasResults":11,"nctId":308,"briefTitle":309,"officialTitle":310,"acronym":311,"eligibilityCriteria":312,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":313,"targetDuration":4,"studyType":23,"phases":315,"briefSummary":316,"conditions":317,"keywords":321,"overallStatus":124,"whyStopped":4,"lastUpdateSubmitDate":300,"lastUpdatePostDateStruct":327,"startDateStruct":329,"completionDateStruct":331,"leadSponsor":333,"locationsCount":133},"100618643","retrolaminar-analgesia-for-lumbar-surgery-100618643","NCT07334288","Retrolaminar Analgesia for LuMbar Surgery","Efficacy of Ultrasound-Guided Retrolaminar Block Combined With Standard Multimodal Analgesia for Postoperative Pain Management in Lumbar Spine Surgery: A Randomized Controlled Trial","REALM","Inclusion Criteria:\n\n* Adult patients aged 18-80 years\n* Scheduled for elective lumbar spine surgery (with instrumentation)\n* American Society of Anesthesiologists (ASA) physical status I-III\n* Willing and able to provide written informed consent\n* Able to use patient-controlled analgesia (PCA) device\n\nExclusion Criteria:\n\n* Refusal to participate in the study\n* Known allergy to local anesthetics (bupivacaine - levobupivacaine - lidocaine) or any study medication\n* Contraindication to regional anesthesia (infection at injection site, coagulopathy)\n* Chronic opioid use (daily use for \\>3 months prior to surgery)\n* Severe psychiatric disorder that precludes informed consent\n* Emergency surgery\n* Diabetes mellitus with preoperative glucose \\>180 mg\u002Fdl\n* Pregnancy or breastfeeding\n* Body mass index (BMI) \\>40 kg\u002Fm²\n* Reoperation or revision of the same level of previous spinal surgery",{"count":314,"type":22},50,[25],"This randomized controlled trial evaluates the effectiveness of ultrasound-guided retrolaminar nerve block in addition to standard multimodal analgesia for postoperative pain management in patients undergoing lumbar spine surgery. Fifty patients will be randomly assigned to receive either the retrolaminar block combined with standard pain management or standard pain management alone. The primary outcome is total opioid consumption in the first 24 hours after surgery. Secondary outcomes include pain intensity at multiple time points, time to first rescue analgesia, duration of sensory block, incidence of postoperative nausea and vomiting, length of hospital stay, patient satisfaction, and chronic pain development at 3 and 6 months follow-up.",[65,318,319,320,30],"Lumbar Surgery","Back Pain Lower Back Chronic","Opioid Analgesia",[322,323,324,325,269,326],"retrolaminar block","regional anesthesia","lumbar spine surgery","Multimodal analgesia","Ultrasound-guided nerve block",{"date":328,"type":41},"2026-04-13",{"date":330,"type":41},"2026-03-01",{"date":332,"type":22},"2027-06-01",{"name":334,"class":48},"Universidad de los Andes, Chile",{"id":336,"slug":337,"hasResults":11,"nctId":338,"briefTitle":339,"officialTitle":339,"acronym":4,"eligibilityCriteria":340,"healthyVolunteers":11,"sex":17,"minAge":4,"maxAge":18,"enrollmentInfo":341,"targetDuration":4,"studyType":113,"phases":4,"briefSummary":343,"conditions":344,"keywords":4,"overallStatus":124,"whyStopped":4,"lastUpdateSubmitDate":345,"lastUpdatePostDateStruct":346,"startDateStruct":348,"completionDateStruct":350,"leadSponsor":351,"locationsCount":133},"100587346","regional-analgesia-at-the-pediatric-emergency-department-100587346","NCT06927193","Regional Analgesia at the Pediatric Emergency Department","Inclusion Criteria:\n\n* Children who visited the pediatric emergency department between 2023-2025 and underwent a nerve block during their visit.\n\nExclusion Criteria:\n\n* Children who visited the emergency department but had the nerve block performed outside the emargency department setting (e.g., inpatient wards or operationg room), or if the block was performed by a physician not affiliated with the pediatric emergency department.",{"count":342,"type":22},400,"Approximately two years ago, ultrasound-guided regional blocks technique was introduced into routine use in the pediatric emergency department at Hillel Yaffe Medical Center. Since then, nearly 300 different blocks have been performed.\n\nStudy Objective: To collect a registry database of complication rates associated with regional analgesia during routine pediatric emergency department care between 2023 and 2025.",[30],"2026-04-06",{"date":347,"type":41},"2026-04-09",{"date":349,"type":41},"2026-01-01",{"date":43,"type":22},{"name":352,"class":103},"Hillel Yaffe Medical Center",{"id":354,"slug":355,"hasResults":11,"nctId":356,"briefTitle":357,"officialTitle":358,"acronym":4,"eligibilityCriteria":359,"healthyVolunteers":11,"sex":17,"minAge":360,"maxAge":4,"enrollmentInfo":361,"targetDuration":4,"studyType":23,"phases":363,"briefSummary":364,"conditions":365,"keywords":4,"overallStatus":124,"whyStopped":4,"lastUpdateSubmitDate":367,"lastUpdatePostDateStruct":368,"startDateStruct":370,"completionDateStruct":372,"leadSponsor":374,"locationsCount":133},"100619948","erector-spinae-plane-block-versus-lateral-transversus-abdominis-plane-block-for-open-abendectomy-surgery-100619948","NCT07351253","Erector Spinae Plane Block Versus Lateral Transversus Abdominis Plane Block for Open Abendectomy Surgery","Analgeisc Effect of Erector Spinae Plane Block Versus Lateral Transversus Abdominis Plane Block in Patients Undergoing Open Abendectomy Surgery: a Randomized Controlled Trial","Inclusion Criteria:\n\n* adult patients, undergoing open appendectomy.\n\nExclusion Criteria:\n\n* American society of anesthesiologist-physical status \\>III,\n* allergy to any of the study drugs,\n* coagulopathy\n* local infection,\n* history of chronic pain or regular opioid use;\n* inability to comprehend the Numeric Rating Scale (NRS),\n* pregnant or lactating women.","21 Years",{"count":362,"type":22},68,[25],"this aim of this study is to compare the analgesic effect of Erector spinae plane (ESP) block and lateral transversus abdominis plan (TAP) block in patients undergoing open appendectomy.",[366,117,30],"Appendicectomy","2026-03-15",{"date":369,"type":41},"2026-03-17",{"date":371,"type":41},"2026-01-25",{"date":373,"type":22},"2026-05",{"name":375,"class":48},"Cairo University",{"id":377,"slug":378,"hasResults":11,"nctId":379,"briefTitle":380,"officialTitle":381,"acronym":4,"eligibilityCriteria":382,"healthyVolunteers":11,"sex":17,"minAge":383,"maxAge":384,"enrollmentInfo":385,"targetDuration":4,"studyType":23,"phases":386,"briefSummary":387,"conditions":388,"keywords":391,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":394,"lastUpdatePostDateStruct":395,"startDateStruct":397,"completionDateStruct":398,"leadSponsor":399,"locationsCount":133},"100617676","sacral-erector-spinae-plane-block-versus-penile-block-for-analgesia-in-pediatric-circumcision-100617676","NCT07321717","Sacral Erector Spinae Plane Block Versus Penile Block For Analgesia In Pediatric Circumcision","A Randomized Controlled Trial Comparing The Analgesic Effectiveness Of Sacral Erector Spinae Plane Block And Penile Block In Children Undergoing Circumcision Surgery","Inclusion Criteria:\n\n* Age between 1 and 12 years\n* Scheduled for circumcision surgery\n* Classified as American Society of Anesthesiologists (ASA) physical status I-II\n* Written informed consent obtained from both the participant (when appropriate) and their parents or legal guardians\n\nExclusion Criteria:\n\n* Age under 1 year or over 12 years\n* Undergoing circumcision combined with other surgical procedures\n* Presence of neurological deficits\n* History of bleeding diathesis\n* Allergy to local anesthetic (LA) drugs\n* Redness or infection at the injection site\n* Presence of congenital sacral anomalies\n* Mental retardation\n* Psychiatric disorders or kidney disease\n* Refusal to participate in the study","1 Year","12 Years",{"count":58,"type":22},[25],"Circumcision is one of the most frequently performed surgical procedures in childhood and is associated with significant postoperative pain. This randomized controlled trial (RCT) aims to compare the analgesic effectiveness of sacral erector spinae plane block (sacral ESPB) and penile nerve block (PNB) in children undergoing circumcision surgery. The primary outcome is postoperative pain, assessed using the Face, Legs, Activity, Cry, and Consolability (FLACC) scale at predefined time intervals within the first 24 hours after surgery. Secondary outcomes include intraoperative analgesic consumption, time to first postoperative analgesic requirement, perioperative hemodynamic changes. The results of this study are expected to provide evidence for selecting the optimal regional analgesic technique for pediatric circumcision surgery.",[389,390,30],"Sacral Erector Spinae Plane Block","Pediatric Regional Anesthesia",[392,393],"pediatric regional anesthesia","sacral ESP","2025-12-23",{"date":396,"type":41},"2026-01-07",{"date":349,"type":22},{"date":300,"type":22},{"name":400,"class":48},"Istanbul University - Cerrahpasa",{"id":402,"slug":403,"hasResults":11,"nctId":404,"briefTitle":405,"officialTitle":405,"acronym":406,"eligibilityCriteria":407,"healthyVolunteers":11,"sex":17,"minAge":56,"maxAge":4,"enrollmentInfo":408,"targetDuration":4,"studyType":113,"phases":4,"briefSummary":410,"conditions":411,"keywords":414,"overallStatus":124,"whyStopped":4,"lastUpdateSubmitDate":420,"lastUpdatePostDateStruct":421,"startDateStruct":423,"completionDateStruct":425,"leadSponsor":427,"locationsCount":133},"100616743","regional-versus-general-anesthesia-for-hip-fracture-and-postoperative-oxygenation-100616743","NCT07309575","Regional Versus General Anesthesia for Hip Fracture and Postoperative Oxygenation","REGENERATION","Inclusion Criteria:\n\n* hospital admission for hip fracture;\n* scheduled for hip fracture surgery;\n* age above 65 years, both genders;\n* capable of consent or consent by responsible person;\n\nExclusion Criteria:\n\n* hip fracture during hospitalization (not present upon admission)\n* patient refusal to participate",{"count":409,"type":22},102,"With this study, the investigators intend to measure oxygen saturation before and after hip surgery in the context of proximal femur fracture, comparing two types of anesthesia (general or spinal). The investigators also intend to study the effects of the two anesthetic techniques on sleep apnea, delirium, respiratory complications, and length of hospital stay.\n\nThis is an observational study, in which oxygen is measured at the fingertip with a sensor and a bracelet, without any intervention, inconvenience, or discomfort for the participant. Data will be collected on: respiratory complications, sleep apnea, delirium, length of hospital stay, and survival.\n\nData will be collected in the operating room and wards of Santa Maria Hospital, Lisbon, Portugal over a period of approximately 24 hours after the participant's operation. Information about participant's health and co-morbidities will be recorded.\n\nThere will be no implication for the participants' clinical care, since the study measurements will not be sent to the health professionals in charge. The operation, recovery, and treatments will not be influenced at any time by participation in the study.",[412,413,30],"Hip-fracture","General Anaesthesia",[415,416,417,418,419],"anaesthesia","hip femur fracture","postoperative pulmonary complications","oxygenation","sleep apnea","2025-12-19",{"date":422,"type":41},"2025-12-30",{"date":424,"type":41},"2025-11-27",{"date":426,"type":22},"2026-12",{"name":428,"class":48},"University of Lisbon",{"id":430,"slug":431,"hasResults":11,"nctId":432,"briefTitle":433,"officialTitle":434,"acronym":4,"eligibilityCriteria":435,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":56,"enrollmentInfo":436,"targetDuration":4,"studyType":23,"phases":438,"briefSummary":440,"conditions":441,"keywords":442,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":448,"lastUpdatePostDateStruct":449,"startDateStruct":451,"completionDateStruct":452,"leadSponsor":453,"locationsCount":133},"100614448","phase-1-ultrasound-guided-infraclvicular-block-using-dexmedetomidine-versus-nalbuphine-as-adjuvants-to-bupivacaine-in-upper-limb-orthopedic-surgery-100614448","NCT07279727","Ultrasound-Guided Infraclvicular Block Using Dexmedetomidine Versus Nalbuphine as Adjuvants to Bupivacaine in Upper Limb Orthopedic Surgery","Ultrasound-Guided Infraclvicular Block Using Dexmedetomidine Versus Nalbuphine as Adjuvants to Bupivacaine in Upper Limb Orthopedic Surgery: A Prospective, Randomized, Double-Blind Controlled Study","Inclusion Criteria:\n\nAdults aged 18-65 years ASA I-II (American Society of Anesthesiologists physical status classification) Scheduled for elective upper limb orthopedic surgeries Able to provide informed consent to participate in the study\n\nExclusion Criteria:\n\nRefusal to participate in the study Pregnancy Allergy to any study drug(s) Neurological disease (e.g., neuropathies, central nervous system disorders) Coagulopathy or active bleeding disorders Severe systemic diseases (e.g., uncontrolled cardiovascular, renal, or liver disease) Opioid abuse or history of substance use disorder",{"count":437,"type":22},66,[439],"PHASE1","this study is designed to evaluate and compare the efficacy of dexmedetomidine and nalbuphine as adjuvants to 0.5% bupivacaine in ultrasound-guided infraclavicular brachial plexus block for patients undergoing elective upper limb orthopedic surgeries on the duration of analgesia.",[30],[443,444,445,446,447],"Nalbuphine","Dexmedetomidine","Duration of analgesia","Bupivacaine","Infraclavicular block","2025-12-10",{"date":450,"type":41},"2025-12-12",{"date":349,"type":22},{"date":45,"type":22},{"name":454,"class":48},"Assiut University",{"id":456,"slug":457,"hasResults":11,"nctId":458,"briefTitle":459,"officialTitle":460,"acronym":461,"eligibilityCriteria":462,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":56,"enrollmentInfo":463,"targetDuration":4,"studyType":23,"phases":464,"briefSummary":465,"conditions":466,"keywords":4,"overallStatus":124,"whyStopped":4,"lastUpdateSubmitDate":472,"lastUpdatePostDateStruct":473,"startDateStruct":475,"completionDateStruct":477,"leadSponsor":479,"locationsCount":133},"100610896","preoperative-maxillary-nerve-block-and-remifentanil-use-in-septorhinoplasty-100610896","NCT07233538","Preoperative Maxillary Nerve Block and Remifentanil Use in Septorhinoplasty","Effect of Preoperative Ultrasound-guided Bilateral Maxillary Nerve Block Via the Pterygopalatine Fossa on Intraoperative Remifentanil Use in Septorhinoplasty","PRISM","Inclusion Criteria:\n\n* Those with an ASA (American Society of Anesthesiologists) score of I-II\n* Those with a body mass index (BMI) between 18 and 30\n* Those scheduled for elective surgery\n* Those who are fully cooperative Patients who meet the criteria for septorhinoplasty surgery\n\nExclusion Criteria:\n\n* Conditions that constitute a relative contraindication to regional anesthesia (e.g., coagulation disorders, thrombocytopenia, severe valvular heart disease, local infection at the injection site, allergy to local anesthetic agents)\n* International Normalized Ratio (INR) \\> 1.5\n* Facial paralysis or a history of facial paralysis\n* History of central nervous system vascular disease\n* Presence of neuropathy\n* History of surgery in the region where the block will be performed\n* American Society of Anesthesiologists (ASA) physical status classification of III or higher\n* Patients who do not want to participate in the study\n* Patients with chronic pain or chronic opioid use\n* Patients with alcohol, substance or drug addiction\n* Patients with limited cooperation such as dementia, psychiatric disorders\n* Pregnant and breastfeeding patients will be excluded from the study.\n* Patients who cannot communicate in their native language will be excluded from the study",{"count":112,"type":22},[25],"Septorhinoplasty is generally a prolonged surgical procedure that frequently involves osteotomy, which may lead to increased intraoperative remifentanil requirements. Moreover, it is often associated with significant bleeding due to the dense capillary network of the nasal region, making the maintenance of low-to-normal blood pressure preferable during surgery. Consequently, achieving stable hemodynamics and providing sufficient analgesia throughout the procedure is essential.\n\nThis study aims to evaluate the effects of bilateral maxillary nerve block on intraoperative remifentanil consumption and postoperative analgesic efficacy in patients undergoing Septorhinoplasty. A total of 90 patients will be included in the study. Forty-five patients (Group M) will undergo Septorhinoplasty under general anesthesia combined with bilateral maxillary nerve block, while the remaining 45 patients (Group N) will receive general anesthesia alone.\n\nIn the preoperative phase, a bilateral maxillary nerve block will be performed under ultrasound guidance via the pterygopalatine fossa. During the intraoperative period, total remifentanil consumption will be recorded, alongside assessments of hemodynamic stability, sevoflurane consumption, extubation time, intraoperative bleeding volume, and the satisfaction levels of both the anesthesiologist and the surgeon.\n\nIn the postoperative period, patient satisfaction, pain scores at 0, 1, 2, 4, 6, 12, 18, and 24 hours as well as at 1 month (measured using the Visual Analog Scale - VAS), additional analgesic requirements, and Quality of Recovery-15 (QoR-15) scores (assessed on preoperative day 1, postoperative day 1, and at 1 month) will be evaluated.",[467,468,469,470,30,471],"Head and Neck Surgery","Plastic Surgery","Rhinoplasty","Pain","Nerve Blocks","2025-11-17",{"date":474,"type":41},"2025-11-18",{"date":476,"type":41},"2025-08-20",{"date":478,"type":22},"2026-12-08",{"name":102,"class":103},{"id":481,"slug":482,"hasResults":11,"nctId":483,"briefTitle":484,"officialTitle":485,"acronym":4,"eligibilityCriteria":486,"healthyVolunteers":11,"sex":17,"minAge":56,"maxAge":4,"enrollmentInfo":487,"targetDuration":4,"studyType":23,"phases":488,"briefSummary":489,"conditions":490,"keywords":493,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":495,"lastUpdatePostDateStruct":496,"startDateStruct":498,"completionDateStruct":499,"leadSponsor":501,"locationsCount":4},"100593998","transversus-abdominis-plane-block-on-postoperative-analgesic-efficacy-in-elderly-patients-undergoing-minimally-invasive-gastrointestinal-tumor-surgery-100593998","NCT07013721","Transversus Abdominis Plane Block on Postoperative Analgesic Efficacy in Elderly Patients Undergoing Minimally Invasive Gastrointestinal Tumor Surgery","A Clinical Study on the Effect of Ultrasound-Guided Transversus Abdominis Plane Block on Postoperative Analgesic Efficacy in Elderly Patients Undergoing Minimally Invasive Gastrointestinal Tumor Surgery","Inclusion Criteria:\n\n1. Elderly patients scheduled for elective minimally invasive gastrointestinal tumor surgery under general anesthesia\n2. Age ≥65 years\n3. American Society of Anesthesiologists (ASA) physical status classification ≤III\n4. Body mass index (BMI) 18-30 kg\u002Fm²\n\nExclusion Criteria:\n\n1. Allergy to anesthetic agents\n2. Preoperative chronic pain or chronic use of opioids\u002Fnonsteroidal anti-inflammatory drugs (NSAIDs)\n3. Contraindications to regional blockade:Local infection at puncture site\n\n   , Coagulopathy (INR \\>1.5, platelet count \\\u003C80×10⁹\u002FL)\n4. There is cognitive impairment, which is determined based on Mini Mental State Examination (MMSE) scores below the standard threshold\n5. Preoperative neurological\u002Fpsychiatric disorders:Consciousness alterations, Epilepsy, Alzheimer's disease, Parkinson's disease, Schizophrenia, Anxiety or depressive disorders, Hepatic, pulmonary, or renal encephalopathy\n6. Recent stroke history\n7. Postoperative admission to intensive care unit (ICU)",{"count":409,"type":22},[25],"Elderly patients undergoing minimally invasive gastrointestinal tumor surgery face complex postoperative pain management due to age-related physiological decline and surgical particularities, where traditional opioids are prone to adverse effects. Our study investigates the clinical analgesic efficacy of ultrasound-guided transversus abdominis plane block (TAPB) in these patients, focusing on analgesic quality, delirium incidence, opioid consumption, and postoperative recovery indicators. This evaluation aims to assess its clinical value and safety while providing evidence-based insights for optimizing perioperative analgesia protocols.",[30,491,492],"Transversus Abdominis Plane Block (TAP Block)","Pain, Postoperative",[30,494,492],"Transversus abdominis plane block (TAP block)","2025-06-02",{"date":497,"type":41},"2025-06-10",{"date":495,"type":22},{"date":500,"type":22},"2026-04-15",{"name":502,"class":48},"Chinese PLA General Hospital",{"id":504,"slug":505,"hasResults":11,"nctId":506,"briefTitle":507,"officialTitle":508,"acronym":509,"eligibilityCriteria":510,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":228,"enrollmentInfo":511,"targetDuration":4,"studyType":23,"phases":513,"briefSummary":514,"conditions":515,"keywords":517,"overallStatus":124,"whyStopped":4,"lastUpdateSubmitDate":523,"lastUpdatePostDateStruct":524,"startDateStruct":526,"completionDateStruct":528,"leadSponsor":530,"locationsCount":133},"100577071","comparison-of-the-efficacy-of-celiac-plexus-blockade-esp-and-lidocaine-infusion-under-ofa-100577071","NCT06793527","Comparison of the Efficacy of Celiac Plexus Blockade, ESP and Lidocaine Infusion Under OFA","Comparison of the Efficacy of Celiac Plexus Blockade, Erector Spinae Compartment Blockade (ESP), and Intravenous Lidocaine Infusion Under Opioid-free Anesthesia in Patients Undergoing Bariatric Surgery","LECO","Inclusion Criteria:\n\n* Patients over 18 years who underwent laparoscopic bariatric surgery\n* Must be able to sign agreement for study\n\nExclusion Criteria:\n\n* Patients with a history of allergic reactions to drugs\n* Patients with a history of drug addiction\n* Patients with chronic pain who require analgesics\n* History of hospitalization for psychiatric disorders\n* Preoperative pulse oximetry (SpO2) \\\u003C 95 %\n* bradycardia (HR\\\u003C50bpm)\n* hypotension\n* atrioventricular block\n* intraventricular or sinus block\n* Blood clotting disorders\n* Pregnant\u002Flactating women\n* Cognitive impairment\n* Unable to read consent",{"count":512,"type":22},300,[25],"Modern anesthesiology, in search of alternatives to opioid-based pain management, is turning to low-opioid and non-opioid protocols. Replacing opioids with non-opioid analgesics, co-analgesics, and regional and local anesthesia techniques allows avoiding the adverse effects of opioids while maintaining satisfactory analgesia. This is of particular importance in bariatric surgery, where reducing the incidence of respiratory depression, sedation, opioid hyperalgesia, and postoperative nausea and vomiting is a priority. Standard non-opioid anesthesia (OFA) includes ketamine, lidocaine, and dexmedetomidine infusions, while regional techniques additionally reduce the need for analgesics. Despite the widespread use of these methods, there is no clear data on the superiority of any of them in bariatric procedures.",[30,516],"Anesthesia and Analgesia",[518,519,520,521,522],"ESP","celiac plexus block","OFA","erector spinal plane block","opioid free anesthesia","2025-04-02",{"date":525,"type":41},"2025-04-04",{"date":527,"type":41},"2025-02-06",{"date":529,"type":22},"2026-12-31",{"name":531,"class":48},"Jagiellonian University",{"id":533,"slug":534,"hasResults":11,"nctId":535,"briefTitle":536,"officialTitle":537,"acronym":4,"eligibilityCriteria":538,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":539,"enrollmentInfo":540,"targetDuration":4,"studyType":23,"phases":541,"briefSummary":542,"conditions":543,"keywords":545,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":550,"lastUpdatePostDateStruct":551,"startDateStruct":553,"completionDateStruct":555,"leadSponsor":557,"locationsCount":133},"100582542","a-comparative-study-of-combined-adductor-canal-and-interspace-between-popliteal-artery-and-knee-capsule-versus-combined-adductor-canal-and-genicular-nerve-in-total-knee-arthroplasty-100582542","NCT06864663","A Comparative Study of Combined Adductor Canal and Interspace Between Popliteal Artery and Knee Capsule Versus Combined Adductor Canal and Genicular Nerve in Total Knee Arthroplasty","A Comparative Study of Combined Ultrasound-Guided Adductor Canal Block and Interspace Between the Popliteal Artery and Capsule of the Knee (IPACK) Versus Combined Adductor Canal Block and Genicular Nerve Block Following Total Knee Arthroplasty","Inclusion Criteria:\n\n1. Patients American Society of anesthesiologists' physical status (ASA) I to III.\n2. Aged 18 to 70 years.\n3. Both sexes.\n4. Patients scheduled for total knee arthroplasty.\n\nExclusion Criteria:\n\n1. Patient refusal\n2. ASA physical status IV or more.\n3. Patients with known allergy to any of the study drugs.\n4. Infection at the site of injection.\n5. Patients with neuromuscular disease.\n6. Presence of any coagulopathy.\n7. Patients with history of any psychiatric or cognitive disorder.\n8. patient with previous knee surgery.\n9. BMI more than 40 kg\u002Fm2.","70 Years",{"count":285,"type":22},[25],"The aim of this study is to investigate the effectiveness of combined adductor canal block (ACB) with interspace between popliteal artery and the knee capsule (IPACK) versus combined ACB with genicular nerve block (GNB) for providing analgesia in knee arthroplasty. The investigators hypothesize that the analgesic efficacy of ACB combined with GNB will be non-inferior to that of ACB combined with IPACK. Additionally, the investigators aim to assess whether the combination of ACB and GNB results in a significantly lower occurrence of sensory or motor block affecting the tibial and common peroneal nerves compared to ACB and IPACK",[544,30],"Nerve Block",[546,547,548,549],"adductor canal block","interspace between popliteal artery and capsule of knee","knee arthroplasty","genicular nerve block","2025-03-06",{"date":552,"type":41},"2025-03-07",{"date":554,"type":22},"2025-03-15",{"date":556,"type":22},"2025-10-15",{"name":558,"class":48},"Ain Shams University"]