[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"regional-anesthesia-block\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:regional-anesthesia-block":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,6,0,[8,42,78,105,134,172],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":4,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":30,"lastUpdatePostDateStruct":31,"startDateStruct":34,"completionDateStruct":36,"leadSponsor":38,"locationsCount":41},"100632755","comparison-between-ultrasound-guided-costoclavicular-and-lateral-sagittal-infraclavicular-brachial-plexus-blocks-in-adult-distal-upper-limb-surgeries-100632755",false,"NCT07517809","Comparison Between Ultrasound-Guided Costoclavicular and Lateral-Sagittal Infraclavicular Brachial Plexus Blocks in Adult Distal Upper Limb Surgeries","Comparison Between Ultrasound-Guided Costoclavicular and Lateral-Sagittal Infraclavicular Brachial Plexus Blocks in Adult Distal Upper Limb Surgeries : A Randomized Controlled Trial","Inclusion Criteria:\n\n* ASA physical status I-III\n* Distal upper limb surgery requiring brachial plexus block.\n* Patient approval after written and informed consent to participate.\n\nExclusion Criteria:\n\n* Patient refusal.\n* Allergy to drugs used.\n* Infection at puncture site.\n* Coagulopathy or anticoagulant therapy.\n* Pre-existing neuropathy or neurological deficit in the affected limb.\n* Severe pulmonary disease.\n* BMI \\> 40 kg\u002Fm².","ALL","21 Years","65 Years",{"count":20,"type":21},50,"ESTIMATED","INTERVENTIONAL",[24],"NA","The aim of the study is to compare the onset time of the costoclavicular approach of brachial plexus block with that of the lateral-sagittal infraclavicular approach in adults distal upper limb surgeries.",[27,28],"Regional Anesthesia Block","Brachial Plexus Blocks","RECRUITING","2026-06-22",{"date":32,"type":33},"2026-06-24","ACTUAL",{"date":35,"type":33},"2026-02-16",{"date":37,"type":21},"2026-09",{"name":39,"class":40},"Ain Shams University","OTHER",1,{"id":43,"slug":44,"hasResults":11,"nctId":45,"briefTitle":46,"officialTitle":47,"acronym":48,"eligibilityCriteria":49,"healthyVolunteers":50,"sex":16,"minAge":51,"maxAge":4,"enrollmentInfo":52,"targetDuration":4,"studyType":22,"phases":54,"briefSummary":56,"conditions":57,"keywords":60,"overallStatus":68,"whyStopped":4,"lastUpdateSubmitDate":69,"lastUpdatePostDateStruct":70,"startDateStruct":72,"completionDateStruct":74,"leadSponsor":76,"locationsCount":4},"100636486","phase-4-study-of-ql-analgesic-response-and-extent-100636486","NCT07566312","Study of QL Analgesic Response and Extent","Anterior Versus Posterior Versus Lateral Quadratus Lumborum Block: a Randomized Control Trial in Healthy Volunteers","SQUARE","Inclusion Criteria:\n\n* Ability to provide written informed consent\n* Ability and willingness to comply with the study procedures and duration requirements\n* ASA physical status 1 or 2\n* Age ≥ 18 years\n* Weight \\> 70kg\n\nExclusion Criteria:\n\n* BMI \\> 35kg.m2\n* Use of analgesics within 24 hours before the procedure\n* History of thoracic trauma or surgery\n* Abdominal deformities or abnormalities that may prevent proper block performance\n* Abdominal tattoos in the area of block performance\n* Systemic neuromuscular disease\n* Contraindications to regional anesthesia (e.g., infection, allergy, challenging sonoanatomy)\n* Structures are unable to be visualized by ultrasound\n* Pregnancy\n* Other known health conditions that would affect the participant's ability to successfully complete the study",true,"18 Years",{"count":53,"type":21},25,[55],"PHASE4","A total of 14-18 healthy volunteers will be included. There will be three different procedure days, separated by at least one week. On each visit, the subjects will receive a QL block, according to the randomization process. Each volunteer will undergo pre-procedure screening on the first visit. The blocks will be performed on the same side, by the same anesthesiologist, with at least one week between each block. An anterior QL block will be administered on one day, a posterior QL block on another, and a lateral QL block on the third. The order will be randomized, and both the subject and the research team member assessing the block will be blinded. To compare the dermatomal sensory block distribution, the investigators will use detailed mapping with pinprick, cold, and heat stimuli. A handheld dynamometric assessment of lower extremity strength. The testing will be performed 60 to 90 minutes after performance of the blocks.",[58,59,27],"Acute Pain","Postoperative Pain",[61,62,63,64,65,66,67],"Quadratus lumborum block","QL block","QL","Quadratus lumborum","Fascial plane block","Regional anesthesia","Abdominal blocks","NOT_YET_RECRUITING","2026-04-29",{"date":71,"type":33},"2026-05-05",{"date":73,"type":21},"2026-05",{"date":75,"type":21},"2026-12",{"name":77,"class":40},"Duke University",{"id":79,"slug":80,"hasResults":11,"nctId":81,"briefTitle":82,"officialTitle":82,"acronym":4,"eligibilityCriteria":83,"healthyVolunteers":11,"sex":84,"minAge":51,"maxAge":85,"enrollmentInfo":86,"targetDuration":4,"studyType":22,"phases":88,"briefSummary":89,"conditions":90,"keywords":92,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":96,"lastUpdatePostDateStruct":97,"startDateStruct":99,"completionDateStruct":101,"leadSponsor":103,"locationsCount":41},"100615442","tap-block-versus-esp-block-in-patients-undergoing-elective-cesarean-section-a-randomized-controlled-trial-100615442","NCT07292662","TAP Block Versus ESP Block in Patients Undergoing Elective Cesarean Section: a Randomized Controlled Trial","Inclusion Criteria:\n\n* Age between 18 and 45 years\n* Elective cesarean section\n* Ability to provide informed consent\n\nExclusion Criteria:\n\n* Allergy to any of the drugs used in the study\n* Heart disease with impaired cardiac function\n* Stage III or higher kidney failure\n* Coagulation disorders (platelets \\\u003C100,000\u002FμL or INR \\>1.5) or severe liver disease\n* Degenerative central nervous system diseases or peripheral neuropathies\n* Previous uterine surgery (e.g., myomectomy)\n* Previous cesarean section\n\nPre-pregnancy weight \\\u003C55 kg","FEMALE","45 Years",{"count":87,"type":21},90,[24],"This study is comparing two types of pain relief techniques-TAP block and ESP block-for women having an elective cesarean section. Both techniques involve injecting local anesthetic under ultrasound guidance to numb nerves and reduce pain after surgery. The TAP block mainly relieves pain in the abdominal wall, while the ESP block may reduce both abdominal wall and deeper, organ-related pain. The main goal is to see if there's a difference in pain at rest six hours after surgery. The study will also look at pain at later time points, the amount of opioid medication needed, how quickly women can walk, and when they start breastfeeding.\n\nA total of 156 women will be randomly assigned to receive one of the two blocks after standard spinal anesthesia. Pain will be measured using a simple 0-10 scale at 6, 12, and 24 hours, both at rest and during movement. The study follows strict ethical rules, ensures patient privacy, and all results-whether positive or negative-will be shared to help improve pain management after cesarean delivery.",[91,27],"Cesarean Delivery",[93,94,95],"ESP block","TAP block","cesarean section","2026-04-09",{"date":98,"type":33},"2026-04-13",{"date":100,"type":33},"2026-01-07",{"date":102,"type":21},"2027-10",{"name":104,"class":40},"University of Padova",{"id":106,"slug":107,"hasResults":11,"nctId":108,"briefTitle":109,"officialTitle":109,"acronym":110,"eligibilityCriteria":111,"healthyVolunteers":11,"sex":16,"minAge":51,"maxAge":4,"enrollmentInfo":112,"targetDuration":4,"studyType":114,"phases":4,"briefSummary":115,"conditions":116,"keywords":118,"overallStatus":68,"whyStopped":4,"lastUpdateSubmitDate":125,"lastUpdatePostDateStruct":126,"startDateStruct":128,"completionDateStruct":130,"leadSponsor":132,"locationsCount":4},"100611311","neurological-events-and-unforeseen-risks-after-locoregional-anesthesia-100611311","NCT07238933","Neurological Events and Unforeseen Risks After Locoregional-anesthesia","NEURAL","Inclusion Criteria:\n\n* Age ≥ 18 years.\n* Scheduled to undergo a single-shot nerve or fascial plane block.\n* Ability to provide written informed consent.\n\nExclusion Criteria:\n\n* Performance of more than one single-shot nerve or fascial plane block within the same anatomical region or sensory distribution during the same procedure.\n* Use of continuous nerve or fascial plane catheter-based anesthesia.\n* Presence of a language barrier that, in the investigator's judgment, would prevent adequate follow-up.",{"count":113,"type":21},3396,"OBSERVATIONAL","This is a multicenter, prospective, observational study aimed at determining the incidence of neurological and non-neurological complications following locoregional anesthesia procedures. The study will collect data on events such as nerve injury, hematoma, pneumothorax, and local anesthetic systemic toxicity.",[117,27],"Regional Anesthesia",[119,120,121,122,123,124,65],"Nerve Injury","Pneumothorax","Local Anesthetic Systemic","Toxicity","Upper limb block","Lower limb block","2025-11-18",{"date":127,"type":33},"2025-11-20",{"date":129,"type":21},"2025-12-01",{"date":131,"type":21},"2027-01-01",{"name":133,"class":40},"Societa Italiana Anestesia Analgesia Rianimazione e Terapia Intensiva",{"id":135,"slug":136,"hasResults":11,"nctId":137,"briefTitle":138,"officialTitle":139,"acronym":4,"eligibilityCriteria":140,"healthyVolunteers":11,"sex":16,"minAge":51,"maxAge":18,"enrollmentInfo":141,"targetDuration":4,"studyType":22,"phases":143,"briefSummary":146,"conditions":147,"keywords":152,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":163,"lastUpdatePostDateStruct":164,"startDateStruct":166,"completionDateStruct":168,"leadSponsor":170,"locationsCount":41},"100597746","phase-2-clonidine-in-ultrasound-guided-rectus-sheath-block-for-outpatient-umbilical-hernioplasty-100597746","NCT07062497","Clonidine in Ultrasound-guided Rectus Sheath Block for Outpatient Umbilical Hernioplasty","Ultrasound-guided Rectus Abdominis Muscle Sheath Block in Outpatient Umbilical Hernioplasties: a Comparative Analysis of the Use of Clonidine as an Adjuvant - Prospective Randomized Clinical Trial","Inclusion Criteria:\n\n* Adults aged 18 to 65 years;\n* Both male and female participants;\n* ASA physical status I or II (American Society of Anesthesiologists classification);\n* Scheduled for elective ambulatory umbilical hernia repair;\n* Hernial defect size ≤ 4 cm (small to medium).\n\nExclusion Criteria:\n\n* Refusal or inability to provide written informed consent;\n* Cognitive or psychiatric disorders that impair comprehension or adherence to the study protocol;\n* Known allergy or hypersensitivity to local anesthetics, clonidine, opioids, nonsteroidal anti-inflammatory drugs (NSAIDs), or other analgesics;\n* Participation in another clinical trial within the previous 30 days;\n* Missing data or loss to follow-up during postoperative assessments;\n* Contraindications to regional anesthesia or known coagulopathy.",{"count":142,"type":21},62,[144,145],"PHASE2","PHASE3","This clinical trial aims to evaluate the effectiveness of an ultrasound-guided nerve block technique as the sole anesthetic method for patients undergoing outpatient umbilical hernia surgery. The procedure, called rectus sheath block (RSB), involves injecting local anesthetic near the abdominal muscles to reduce pain during and after surgery. The study will compare two groups of adult patients: one receiving the nerve block with a medication called clonidine added to the anesthetic solution, and the other receiving the same block without clonidine. Clonidine may help improve pain control and reduce the need for additional pain medications. By analyzing pain scores, recovery quality, and potential side effects, the study seeks to determine whether the use of clonidine in this context is safe, cost-effective, and beneficial for patient recovery. Participants will answer questionnaires about their pain and recovery during the first 48 hours after surgery.",[148,149,150,151,27],"Hernia, Umbilical","Clonidine","Pain, Postoperative","Ambulatory Surgical Procedures",[153,154,155,149,156,157,158,159,160,161,162],"Rectus Sheath Block","Ultrasound-Guided Regional Anesthesia","Umbilical Hernia Repair","Local Anesthetics","Postoperative Pain Management","Ambulatory Surgery","Quality of Recovery","Alpha-2 Adrenergic Agonists","Pain Measurement","Analgesic Adjuvants","2025-07-10",{"date":165,"type":33},"2025-07-14",{"date":167,"type":33},"2025-01-07",{"date":169,"type":21},"2026-04-30",{"name":171,"class":40},"Universidade Federal do Rio de Janeiro",{"id":173,"slug":174,"hasResults":11,"nctId":175,"briefTitle":176,"officialTitle":176,"acronym":4,"eligibilityCriteria":177,"healthyVolunteers":11,"sex":84,"minAge":51,"maxAge":178,"enrollmentInfo":179,"targetDuration":4,"studyType":22,"phases":180,"briefSummary":181,"conditions":182,"keywords":4,"overallStatus":68,"whyStopped":4,"lastUpdateSubmitDate":184,"lastUpdatePostDateStruct":185,"startDateStruct":187,"completionDateStruct":189,"leadSponsor":191,"locationsCount":41},"100592590","transversus-abdominis-plane-block-tap-versus-thoracoabdominal-nerve-block-through-perichondrial-approach-m-tapa-in-laparoscopic-gynecologic-surgeries-100592590","NCT06995404","Transversus Abdominis Plane Block (TAP) Versus Thoracoabdominal Nerve Block Through Perichondrial Approach (M-TAPA) in Laparoscopic Gynecologic Surgeries","Inclusion Criteria:Female patients aged between 18 and 80 years, classified as ASA physical status I to III, undergoing laparoscopic gynecologic surgery under general anesthesia -\n\nExclusion Criteria:Coagulopathy\n\nNeuropathy\n\nChronic analgesic therapy\n\nSevere cardiopulmonary disease\n\nUncontrolled diabetes mellitus (HbA1c \\> 8%)\n\nSevere renal or hepatic failure\n\nPregnancy or lactation\n\nBody mass index (BMI) greater than 35 kg\u002Fm²\n\nLocal infection at the injection site\n\nInability to comprehend pain scores or cooperate (e.g., Alzheimer's disease, mental retardation)\n\nAllergy to local anesthetic agents\n\nRefusal to participate in the study\n\n\\-","80 Years",{"count":87,"type":21},[24],"Although laparoscopic techniques are considered minimally invasive surgical procedures with lower perioperative pain scores compared to open surgeries, they are still associated with significant levels of pain. This study aims to investigate the analgesic effectiveness of two routinely performed regional analgesic techniques in our clinic-ultrasound-guided classic bilateral TAP block and ultrasound-guided bilateral M-TAPA block-in patients undergoing laparoscopic gyneco-oncologic surgery (LGOS), as well as their effects on intraoperative opioid consumption.",[183,27],"Gynecologic Laparoscopic Surgery","2025-05-26",{"date":186,"type":33},"2025-05-29",{"date":188,"type":21},"2025-05-30",{"date":190,"type":21},"2025-06-30",{"name":192,"class":193},"Ankara Etlik City Hospital","OTHER_GOV"]