[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"rehabilitation-exercise\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:rehabilitation-exercise":33},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,15,0,[8,60,99,132,156,182,209,240,262,284,307,335,367,396,425],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":37,"overallStatus":47,"whyStopped":4,"lastUpdateSubmitDate":48,"lastUpdatePostDateStruct":49,"startDateStruct":52,"completionDateStruct":54,"leadSponsor":56,"locationsCount":59},"100603978","early-exercise-based-rehabilitation-in-patients-hospitalized-for-acute-pulmonary-embolism-100603978",false,"NCT07143539","Early Exercise-Based Rehabilitation in Patients Hospitalized for Acute Pulmonary Embolism","Early Exercise-based Rehabilitation in High-risk Patients Hospitalized for Acute Pulmonary Embolism: a Pragmatic Multicenter Randomized Partially Blinded Superiority Trial","RehabPE","Inclusion Criteria:\n\n1. Age ≥18 years\n2. Hospitalization for objectively confirmed acute symptomatic PE, defined as intraluminal filling defect of a segmental or more proximal pulmonary artery on computed tomography pulmonary angiography (CTPA) or a high-probability ventilation-perfusion scintigraphy, and admission within the past 7 days\n3. Increased risk for post-PE syndrome, defined as simplified Pulmonary Embolism Severity Index (sPESI) ≥1 point at the time of admission\n4. Written informed consent\n\nExclusion Criteria:\n\n1. Contraindication to EBR (known unstable cardiac conditions like angina pectoris, severe valvular heart disease, or severe resting pulmonary hypertension)\n2. Medical condition that clearly precludes participation in EBR (e.g., inability to walk, unstable joints, severe neurological impairment)\n3. Recently completed (i.e., \\\u003C6 months), ongoing, or planned in- or outpatient EBR, or planned supervised outpatient physiotherapy for any indication\n4. Planned hospitalization during follow-up (e.g., elective surgery or inpatient chemotherapy)\n5. Contraindication to anticoagulation\n6. Life expectancy \\\u003C1 year based on the treating physician's clinical judgement\n7. Known pregnancy\n8. Inability to speak German or French\n9. Participation in another study that prohibits concurrent participation in RehabPE\n10. Unable to provide informed consent (e.g., due to dementia)\n11. Unwilling to provide informed consent\n12. Prior enrollment in this study","ALL","18 Years",{"count":20,"type":21},160,"ESTIMATED","INTERVENTIONAL",[24],"NA","Up to half of patients with pulmonary embolism (PE) suffer from impaired quality of life, reduced physical capacity, and symptoms like shortness of breath even three months after diagnosis, despite standard treatment with anticoagulation (blood thinners). The randomized RehabPE trial investigates whether an early, structured rehabilitation program with physical training and patient education can prevent such long-term effects.\n\nThe study includes hospitalized patients with acute symptomatic PE who are at increased risk of impaired quality of life three months after diagnosis. After informed consent, patients are randomly assigned to one of two groups: one receives an early 6-8-week, center-based rehabilitation program; the other receives standard follow-up care without rehabilitation. The intervention group completes 16-18 outpatient sessions of endurance and strength training, along with two education sessions covering the condition, treatment, and symptom management.\n\nOver 180 days, changes in quality of life, physical exercise capacity, breathlessness, and psychological symptoms, and the time to return to work \u002F usual daily activities will be monitored and compared between groups.",[27,28,29,30,31,32,33,34,35,36],"Venous Thromboembolism (VTE)","Exercise Therapy","Quality of Life (QOL)","Anxiety Depression","Humans","Exercise Tolerance","Rehabilitation Exercise","Dyspnea","Functional Status","Pulmonary Embolism (Diagnosis)",[38,39,40,41,42,43,44,45,46],"pulmonary embolism","deep vein thrombosis","excercise-based rehabilitation","post-PE syndrome","health-related quality of life","anxiety","depression","dyspnea","impact of early excercise-based rehabilitation","RECRUITING","2026-06-11",{"date":50,"type":51},"2026-06-12","ACTUAL",{"date":53,"type":51},"2025-12-17",{"date":55,"type":21},"2028-06",{"name":57,"class":58},"Insel Gruppe AG, University Hospital Bern","OTHER",6,{"id":61,"slug":62,"hasResults":11,"nctId":63,"briefTitle":64,"officialTitle":65,"acronym":66,"eligibilityCriteria":67,"healthyVolunteers":68,"sex":17,"minAge":69,"maxAge":70,"enrollmentInfo":71,"targetDuration":4,"studyType":22,"phases":73,"briefSummary":74,"conditions":75,"keywords":83,"overallStatus":88,"whyStopped":4,"lastUpdateSubmitDate":89,"lastUpdatePostDateStruct":90,"startDateStruct":92,"completionDateStruct":94,"leadSponsor":96,"locationsCount":98},"100643382","the-act-on-a-geriatric-5-ms-guided-physical-therapy-intervention-for-knee-osteo-arthritis-in-older-adults-100643382","NCT07640529","The ACT-ON: A Geriatric 5-Ms-Guided Physical Therapy Intervention for Knee Osteo-Arthritis in Older Adults.","The ACT-ON: A Geriatric 5-Ms-Guided Physical Therapy Intervention for Knee Osteo-Arthritis in Older Adults: A Randomised Control Trial","5Ms\u002FPT\u002FKOA\u002FOA","Inclusion Criteria:\n\n* Prospective participants will be Saudi Nationals\n* aged 60 years or older\n* with a clinical diagnosis of knee osteoarthritis.\n* individuals must be capable of walking 10 meters independently or with an assistive device\n* self-report the ability to tolerate a one-hour assessment session.\n\nExclusion Criteria:\n\n* severe cognitive impairment\n* knee surgery within the past 6 months.\n* diagnosis of rheumatoid arthritis\n* the presence of unstable comorbidities (e.g., uncontrolled hypertension, heart failure, arrhythmia, severe pulmonary disease requiring oxygen, or a cardiac event in the past 6 months).\n* severe joint instability or deformity.\n* unmanaged severe osteoporosis.\n* a recent intra-articular corticosteroid injection (\\\u003C3 months).\n* active cancer treatment within the past 6 months.\n* non-elective hospitalization for a major illness.\n* surgery within the past 6 months.",true,"55 Years","90 Years",{"count":72,"type":21},40,[24],"The study is a Random control trail study conducted at King Khalid University Hospital in Riyadh, Saudi Arabia, focusing on Application of 5 framework in rehabilitation program of knee arthritis. The study will involve a in each group sample of 20 KOA patients, with a 12-month duration. The sample size was estimated using G\\*Power 3.1 software, and the initial power analysis indicated that 40 participants would be required to achieve 80.0% statistical power. The study's participants will be aged between 55 and 80 years, diagnosed with Knee osteoarthritis, without cognitive impairment, knee surgery in the past 6 months, or unstable comorbidities. The study will involve in-person 16 sessions, with the first two lasting approximately one hour and the remaining session 30-45 minutes. The main outcome measures that will be used in this study are Stay Independent Brochure, Iconographical Falls Efficacy Scale (icon-FES), Timed Up and Go, 2-Minute Walk Test, 5 Time Set to Stand Test AND Arthritis Self-Efficacy Scale 8 Item (ASES-8), Patient-Specific Functional Scale (PSFS), and Patient satisfaction level with Physical Therapy service MedRisk. Data will be taken from direct questions to patients, by filling out the questionnaire via Google Form, and through some tests and SPSS will be used for data analysis, with ANOVA Test intervention scores of the outcome measures.",[76,77,78,79,33,80,81,82],"Rehabilitation","Excercise","Geriatric","Physical Therapy","Rehabilitation Outcome","Knee Osteoarthristis","Knee Osteoarthritis",[84,85,86,87],"5Ms","PT","KOA","OA","NOT_YET_RECRUITING","2026-06-06",{"date":91,"type":51},"2026-06-10",{"date":93,"type":21},"2026-05-15",{"date":95,"type":21},"2026-10-15",{"name":97,"class":58},"King Saud University",1,{"id":100,"slug":101,"hasResults":11,"nctId":102,"briefTitle":103,"officialTitle":104,"acronym":105,"eligibilityCriteria":106,"healthyVolunteers":11,"sex":17,"minAge":107,"maxAge":4,"enrollmentInfo":108,"targetDuration":4,"studyType":22,"phases":110,"briefSummary":111,"conditions":112,"keywords":119,"overallStatus":88,"whyStopped":4,"lastUpdateSubmitDate":123,"lastUpdatePostDateStruct":124,"startDateStruct":126,"completionDateStruct":128,"leadSponsor":130,"locationsCount":98},"100643674","from-exercise-oncology-research-to-clinical-practice-100643674","NCT07635589","From Exercise Oncology Research to Clinical Practice","Bridging the Gap Between Exercise Oncology Research and Its Implementation in Clinical Practice","PAC ICare","Inclusion Criteria:\n\n* Have received a cancer diagnosis (inclusive of primary, recurrent; and\u002For metastatic disease);\n* Over the age of 19 years;\n* Able to participate in mild levels of activity as a minimum;\n* Be pretreatment, or receiving active cancer treatment, or have received cancer treatment within the past six months and are still under active oncology care, or beyond six months if they continue to be under active oncology care;\n* Able to provide informed written consent in English; and\n* Have access to internet service and a device that can support video calling (for online programs).\n\nExclusion Criteria:\n\n* Severe cognitive, physical, psychiatric, or uncontrolled medical condition(s) resulting in an inability to provide consent and\u002For safely participate in the study.","19 Years",{"count":109,"type":21},500,[24],"Building on previous research that shows the benefits of exercise, this study aims to find out how best to implement exercise in real-world settings. The study will assess the feasibility and acceptability of an embedding an automated referral tool and an exercise professional into standard cancer care impacts clinician referral and patient uptake of exercise programming. The study will assess how effective the exercise program is at improving patients' physical health, quality of life, symptom management, and overall wellbeing during different stages of their cancer journey (e.g., before treatment, on treatment, after treatment).",[113,114,115,116,33,117,118],"Cancer","Exercise","Implementation of Evidence Based Programs","Cost Effectiveness","Prehabilitation","Survivorship",[113,114,120,121,122,116],"Implementation Science","Mixed-Methods","Effectiveness-Implementation","2026-06-03",{"date":125,"type":51},"2026-06-09",{"date":127,"type":21},"2026-09-01",{"date":129,"type":21},"2029-12",{"name":131,"class":58},"Melanie Keats",{"id":133,"slug":134,"hasResults":11,"nctId":135,"briefTitle":136,"officialTitle":137,"acronym":4,"eligibilityCriteria":138,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":139,"targetDuration":4,"studyType":22,"phases":141,"briefSummary":143,"conditions":144,"keywords":4,"overallStatus":88,"whyStopped":4,"lastUpdateSubmitDate":147,"lastUpdatePostDateStruct":148,"startDateStruct":150,"completionDateStruct":152,"leadSponsor":154,"locationsCount":4},"100639554","phase-1-olfactory-cell-transplantation-and-intensive-rehabilitation-to-repair-chronic-spinal-cord-injury-100639554","NCT07596563","Olfactory Cell Transplantation and Intensive Rehabilitation to Repair Chronic Spinal Cord Injury","Safety, Feasibility, Efficacy of Olfactory Cell Transplantation Therapy Combined With Intensive Exercise Rehabilitation to Repair Chronic Traumatic Spinal Cord Injury.","Inclusion\u002Fexclusion criteria for participants have been determined in consultation with medical and rehabilitation specialists including a clinician with lived experience of SCI.\n\nInclusion Criteria\n\nParticipants are eligible to be included in the trial only if all the following criteria apply:\n\n1. Have sustained an acquired spinal cord injury a minimum of 4 months prior to consent and have completed their primary rehabilitation;\n2. Have a stable neurological level and functional ability of more than two months in duration;\n3. Are over 18 years and able to give informed consent;\n4. Are AIS A, B or low functioning C (more than 75% of key muscles have a power grade \\\u003C3) as per the International Standards for Neurological Classification of spinal cord injury, and documented by an ISNCSCI\u002FASIA exam performed by a qualified practitioner within the last six months;\n5. Have a thoracic injury or lower cervical (C5-C8) injury;\n6. Are able and willing to attend an exercise program five times per week for the duration of the priming rehabilitation program, with allowance for two weeks recreational leave;\n7. Are able and willing to attend an exercise program five times per week for at least 12 weeks of the regenerative rehabilitation program and then at least three days per week for the remaining 20 weeks, with allowance for four weeks recreational leave;\n8. Are considered by their general practitioner or specialist medical consultant to be fit to receive the cell transplantation and undertake the exercise program (documented approval by general practitioner required).\n\nExclusion Criteria\n\nParticipants are excluded from the trial if any of the following criteria apply:\n\n1. Have a high cervical (C1-C4) injury (excluded due to respiratory risk);\n2. Have significant concomitant central nervous system, peripheral nervous system or musculoskeletal system injuries or disorders limiting their ability to exercise;\n3. Have had recent major trauma or surgery within the last 4 months;\n4. Have an existing stage 3 or 4 pressure ulcer according to the National Pressure Ulcer Advisory Panel classification;\n5. Have endocrinopathy or metabolic disorders of the bone that lead to increased risk of injury from the intense long-term exercise therapy, including but not limited to pathological fractures, Paget's disease, lytic or renal bone disease, and senile osteoporosis;\n6. Have a medical history of exposure to medication(s) known to adversely affect mineral or bone metabolism;\n7. Have significant impairment or disability, including physical, neurological or psychological impairments, in addition to the spinal cord injury;\n8. Have a history of long bone fracture incompletely healed;\n9. Have extensive fixed contractures in the upper or lower limbs;\n10. Have severe spasticity that interferes with ability to exercise;\n11. Have uncontrolled neuropathic pain;\n12. Have autonomic dysreflexia without a management plan;\n13. Have a known allergic sensitivity to antibiotics used in the nerve bridge production process;\n14. Do not have adequate transport options to attend the rehabilitation sessions or the assessments;\n15. Are unable to attend the pre-intervention assessments and the follow-up assessments;\n16. Have any contraindications to FES, MRI, X-ray and other study procedures, such as a cardiac pacemaker, epilepsy, lower limb fracture or pregnancy;\n17. Have any other serious medical condition including but not limited to malignancies, auto-immune disorders (requiring continuous pharmaceutical management), psychiatric, behavioural or drug dependency problems, which are likely to influence the participant's ability to cooperate or, in the opinion of the trial investigator, would prevent adherence to the protocol;\n18. Have symptomatic, radiologically demonstrated, or provocatively demonstrated ischaemic heart disease;\n19. Have current thromboembolic disease;\n20. Are using illicit drugs;\n21. Are participating in other clinical trials (including medication, therapeutic interventions and alternative therapies).\n22. Are unable to tolerate expected exercise load.\n23. Are unable to comply with the assessment regime (such as having claustrophobia which prevents MRI procedures being conducted);\n24. Are unable to demonstrate that they have adequate social\u002Ffamily\u002Fcarer support at home to enable their participation throughout the trial.\n25. Evidence of an active infection, confirmed by testing, of a type that would pose an unacceptable risk for the viability of the nasal biopsy, the cell production, or the nerve bridge production.",{"count":140,"type":21},30,[142],"PHASE1","This is a randomised, blinded and controlled Phase I trial to measure the safety, feasibility and efficacy of a combined cell transplantation and intensive rehabilitation intervention to treat spinal cord injury. The trial aims to examine whether transplantation of olfactory cell nerve bridges combined with intensive rehabilitation is safe and feasible for people living with chronic spinal cord injury in Australia, and whether the intervention improves structural integrity of the spinal cord, functional recovery, overall health, and social wellbeing.\n\nFor the olfactory cell nerve bridge transplant, cells from inside the patient's own nose will be purified and engrafted as 3D cellular nerve bridges. Participants will receive a dose that is dependent on the size of the accessible space within the injury site of the spinal cord with up to 60 million cells being engrafted. The surgery for the transplantation will be performed by a neurosurgeon in which the spinal cord will be exposed to enable the nerve bridges to be placed into the injury site. The duration of the procedure will be 3-4 hours. Surgical notes will be used to monitor adherence to the protocol.\n\nFor intensive exercise rehabilitation, the intervention will be supervised and provided by physiotherapists and exercise physiologists at a for-purpose neurorehabilitation facility. The mode of administration will be one-on-one sessions. The 12- and 32-week rehabilitation programs will consist of up to 3 hours per day at the rehabilitation service providers, for 5 days per week. Participants will attend the provider that is within their geographical area. Over each week, sessions will involve a range and mix of activities which could include, but are not limited to, standing, gait training, upper limb strength, trunk stability\u002Fcore strength, and aerobic training. Throughout the trial, logs of exercise activities will be completed by the participants and staff at the neurorehabilitation gyms. Rehabilitation will start from day 1 of the priming rehabilitation (PR) program and go for 12 weeks, then surgery and cell transplantation will occur at week 1 of the cell transplantation surgery and recover program which is 2 weeks post conclusion of Priming Rehabilitation (PR), followed by 5 weeks of recovery.\n\nRehabilitation is for 32 weeks starting 6 weeks post transplant surgery. Regenerative rehabilitation program is from weeks 1-32 of the regenerative rehabilitation (RR) program.\n\nIf nerve bridge production fails for whatever reason in the weeks prior to surgery, this will start an extension\u002Fcontingency\u002Falternative timeline, where a new nasal biopsy will need to be taken from the participant (along with accompanying tests). The cells will be grown up over the next 4 weeks with an additional week of nerve bridge production, while the participant engages in a further five weeks of priming rehabilitation.",[145,146,33],"Spinal Cord Injury","Neurological Conditions","2026-05-12",{"date":149,"type":51},"2026-05-19",{"date":151,"type":21},"2026-05-01",{"date":153,"type":21},"2031-08-01",{"name":155,"class":58},"Dr Brent McMonagle",{"id":157,"slug":158,"hasResults":11,"nctId":159,"briefTitle":160,"officialTitle":161,"acronym":162,"eligibilityCriteria":163,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":164,"enrollmentInfo":165,"targetDuration":4,"studyType":22,"phases":167,"briefSummary":168,"conditions":169,"keywords":4,"overallStatus":47,"whyStopped":4,"lastUpdateSubmitDate":174,"lastUpdatePostDateStruct":175,"startDateStruct":177,"completionDateStruct":178,"leadSponsor":180,"locationsCount":98},"100623953","severe-chronic-neuropathic-pain-a-treatment-bundle-using-spinal-cord-stimulation-and-multidisciplinary-treatment-to-reduce-pain-and-improve-physical-function-100623953","NCT07403331","Severe Chronic Neuropathic Pain: A Treatment Bundle, Using Spinal Cord Stimulation and Multidisciplinary Treatment, to Reduce Pain and Improve Physical Function.","Optimizing Treatment for Chronic Neuropathic Pain: A Replicated Single Case Experimental Design Evaluating a Treatment Bundle Consisting of Multidisciplinary Rehabilitation and Spinal Cord Stimulation (SCS-R)","SCS-R","Inclusion criteria:\n\n* Peripheral neuropathic pain in one or both legs for \\>6 months due to:\n\n  * (1) Post Spinal Pain Syndrome (type 1 or 2).\n  * (2) Localized nerve damage.\n* The area of the neuropathic pain in the leg(s) must be the dominant pain component.\n* Age ranges from 18-60 years.\n* Previous standard conservative (or surgical) treatment attempted.\n* Opioid use within permissible limits at implantation time (daily opioid dose \\\u003C50 mg OMEQ).\n* Willingness to actively participate in the treatment bundle.\n* Living within reasonable travelling distance from Oslo.\n* Proficiency in understanding oral and written Norwegian, essential to benefit from the program that relies on mutual comprehension, nuanced conversation, and emotional expression, which are language-dependent.\n* Cognitive capacity to provide informed consent.\n* Ability to master the technical aspects of the SCS system (switching programs on the remote control).\n\nExclusion criteria:\n\n* Currently undergoing the claims process for health benefits (e.g., disability pensions from NAV (Norwegian Labour and Welfare Administration).\n* Presenting a psychological or psychiatric disorder that may impact treatment efficacy.\n* Chronic generalized pain conditions.\n* Other pain conditions in the affected area, such as osteoarthritis.\n* Pregnancy.","60 Years",{"count":166,"type":21},10,[24],"People with nerve damage can develop nerve pain. The pain can sometimes be severe and unpredictable, causing odd or alarming sensations - for example, lightning-like or electric shock feelings in the area served by the damaged nerve.\n\nThe investigators will examine a treatment for nerve pain in the legs caused by nerve damage, which can occur after a herniated disc or a bone fracture, with or without surgery.\n\nPrevious research suggests that spinal cord stimulation can relieve nerve pain in the legs after surgery or injury, but its effectiveness is still debated. Other studies show that multidisciplinary treatment helps people with long-term pain to improve their quality of life and to better cope in life. National and international guidelines recommend this kind of multidisciplinary care for long-term pain.\n\nThere has yet been published research on spinal cord stimulation combined with multidisciplinary treatment as a bundle intervention. The investigators therefore want to find out whether this combined approach can reduce nerve pain in the legs and improve physical functioning.",[170,171,33,172,173],"Neuropathic Pain","Multidisciplinary Approach","Acceptance & Commitment Therapy","Spinal Cord Stimulation (SCS)","2026-05-04",{"date":176,"type":51},"2026-05-06",{"date":174,"type":21},{"date":179,"type":21},"2027-07-01",{"name":181,"class":58},"Oslo University Hospital",{"id":183,"slug":184,"hasResults":11,"nctId":185,"briefTitle":186,"officialTitle":187,"acronym":188,"eligibilityCriteria":189,"healthyVolunteers":11,"sex":17,"minAge":190,"maxAge":191,"enrollmentInfo":192,"targetDuration":4,"studyType":22,"phases":193,"briefSummary":194,"conditions":195,"keywords":199,"overallStatus":88,"whyStopped":4,"lastUpdateSubmitDate":201,"lastUpdatePostDateStruct":202,"startDateStruct":204,"completionDateStruct":205,"leadSponsor":207,"locationsCount":98},"100635494","prospective-randomized-parallel-controlled-study-of-brain-computer-interface-integrated-robotic-mirror-therapy-for-post-stroke-upper-limb-motor-function-disorder-100635494","NCT07553416","Prospective, Randomized, Parallel-Controlled Study of Brain Computer Interface Integrated Robotic Mirror Therapy for Post-Stroke Upper Limb Motor Function Disorder","A Prospective, Randomized, Parallel-Controlled Clinical Study Protocol of Non-Invasive Brain Computer Interface Robot Based on Mirror Rehabilitation Theory in the Treatment of Upper Limb Motor Function Disorder After Stroke","BCI-RMT","Inclusion Criteria:\n\n1. Aged 30 to 80 years\n2. Patients with unilateral upper limb motor dysfunction caused by primary ischemic\u002Fhemorrhagic stroke within 1 to 6 months prior to enrollment\n3. Cerebral magnetic resonance diffusion-weighted imaging (DWI) at the time of onset indicating that the stroke lesion is limited to the unilateral basal ganglia region\n4. Modified Rankin Scale (mRS) score of 0 to 2 before stroke onset\n5. Fugl-Meyer Motor Function Assessment of Upper Extremities (FMA-UE) score of 10 to 42\n6. Montreal Cognitive Assessment (MoCA) score \\> 18\n7. Fugl-Meyer Balance Assessment score \\> 6\n8. Normal binocular visual acuity or corrected visual acuity\n9. Normal hearing and intact verbal comprehension ability\n10. Provided written informed consent\n\nExclusion Criteria:\n\n1. Patients with other severe cardiovascular and cerebrovascular diseases and unstable vital signs\n2. Patients with motor dysfunction caused by other etiologies, such as amyotrophic lateral sclerosis, myasthenia gravis, muscular dystrophy, hypokalemic periodic paralysis, spondylitis, arthritis, osteomyelitis, etc.\n3. Patients with severe diseases of the lungs, liver, kidneys and other vital organs\n4. Patients with limb movement impairment caused by diseases such as fractures and arthritis\n5. Modified Ashworth Scale (MAS) score \\> 3\n6. Patients unable to understand and cooperate with limb rehabilitation training due to factors such as severe aphasia\n7. Presence of severe visual field defects or visual impairments (e.g., hemianopsia, hemispatial neglect, etc.\n8. History of previous stroke\n9. A history of severe motor injury and\u002For surgical intervention of the affected upper limb, such as muscle tear, tendon rupture, rhabdomyolysis\n10. Life expectancy of less than 1 year due to the underlying disease\n11. Undergoing major surgery within the past 30 days or planning to undergo major surgery within the next 90 days\n12. Pregnant or lactating women\n13. History of drug or alcohol abuse, head trauma or central nervous system infection; current use of cognition-impairing medications such as psychoactive or sedative drugs\n14. With definite psychiatric and psychological disorders, such as depression, anxiety disorder, obsessive-compulsive disorder, schizophrenia, autism, chronic sleep disorder, consciousness disorder, etc.\n15. Having implanted electronic devices in the body that interfere with magnetic resonance imaging (MRI), such as cochlear implants, cardiac pacemakers\u002Fdefibrillators, drug delivery pumps\n16. Poor compliance of the subject, their family members and caregivers, or inability to complete at least 12 months of follow-up as required by the study\n17. Having been enrolled in other clinical studies that conflict with this study\n18. Judged by the Indication Evaluation Committee as ineligible for or not falling within the scope of this study.","30 Years","80 Years",{"count":72,"type":21},[24],"This study aims to utilize non-invasive brain-computer interface technology in conjunction with mirror therapy to design a new paradigm for rehabilitation robots to induce compensatory movements on the healthy side in stroke patients, evaluate the potential rehabilitation value of this paradigm for patients with severely impaired motor areas on the affected side, explore the neural rehabilitation compensation mechanism, and provide more personalized rehabilitation treatment strategies for patients with post-stroke motor dysfunction.",[196,197,198,33],"Ischemic Stroke","Intracranial Haemorrhage","Brain-Computer Interfaces",[196,197,198,33,200],"Mirror rehabilitation robot","2026-04-22",{"date":203,"type":51},"2026-04-28",{"date":151,"type":21},{"date":206,"type":21},"2027-12-31",{"name":208,"class":58},"Beijing Tiantan Hospital",{"id":210,"slug":211,"hasResults":11,"nctId":212,"briefTitle":213,"officialTitle":214,"acronym":4,"eligibilityCriteria":215,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":216,"targetDuration":4,"studyType":218,"phases":4,"briefSummary":219,"conditions":220,"keywords":229,"overallStatus":47,"whyStopped":4,"lastUpdateSubmitDate":231,"lastUpdatePostDateStruct":232,"startDateStruct":234,"completionDateStruct":236,"leadSponsor":237,"locationsCount":98},"100613051","adherence-to-home-based-exercises-in-musculoskeletal-disorders-100613051","NCT07261553","Adherence to Home-Based Exercises in Musculoskeletal Disorders","Adherence to Home-Based Exercise Programs Among Patients With Musculoskeletal Disorders and Its Influencing Factors","Inclusion criteria:\n\n* Be 18 years of age or older\n* To have a musculoskeletal disease (degenerative, neurological or orthopedic)\n* To be given a home exercise program\n* To have cognitive and language functions to communicate, to be a volunteer\n\nExclusion criteria:\n\n* Those with major psychiatric illness\n* Those with cognitive dysfunction\n* Those with communication disorders, reluctant\u002Freluctant to participate\n* Those with any condition other than a primary degenerative, orthopedic, or neurological disease that could significantly affect exercise adherence, including musculoskeletal or systemic disorders (e.g., severe anemia, heart failure, respiratory failure, uncontrolled diabetes, inflammatory rheumatic disease, recent fractures, or active infections).",{"count":217,"type":21},252,"OBSERVATIONAL","Home exercise program is recommended by physicians to patients and their relatives to do at home and It is a treatment option in which the physician describes how to do it. Home workout program to be completed at home to complement and reinforce their program in the clinic It is a personalized set of therapeutic exercises that are taught. There are factors that can change exercise compliance; There are some reasons why some patients adhere to the prescribed home exercise program and others do not.\n\nAdherence to home exercises is a major issue in rehabilitation and the reasons for this are multifactorial; It includes both psychological and specific conditions factors that vary between each individual and these conditions should be taken into account by clinicians in designing personalized exercise programs.\n\nHome exercise programs constitute a fundamental component of rehabilitation and are widely prescribed by physicians support therapeutic gains beyond the clinical environment. These individualized programs aim to maintain functional improvements, reduce symptoms, and promote self-management among individuals with musculoskeletal disorders. Although adherence to home-based exercises is recognized as a key determinant of rehabilitation outcomes, non-adherence remains a persistent challenge. Despite growing emphasis on the importance of exercise compliance, the existing literature provides relatively limited and insufficient evidence regarding the factors that influence adherence across different musculoskeletal conditions, including degenerative, orthopedic, and neurological disorders.\n\nAddressing this gap, the present prospective longitudinal cohort study aims to evaluate adherence to individualized home-based exercise programs among patients with diverse musculoskeletal conditions and to determine whether adherence behaviors differ across diagnostic groups. In addition, the study seeks to identify demographic, clinical, psychosocial, and functional factors associated with exercise compliance. By integrating structured clinical evaluations with validated outcome measures, this study aims not only to clarify the determinants of exercise adherence but also to contribute to the development of more effective, condition-specific strategies to enhance sustained engagement in home-based rehabilitation.",[221,222,223,33,224,225,226,227,228],"Exercise Training","Adherence, Treatment","Musculoskeletal Disease","Adherence, Patient","Home Exercise Program","Stroke","Orthopedic Operations","Degeneration of Spine and Osteoarticular",[225,230,33,223,224],"adherence","2026-03-21",{"date":233,"type":51},"2026-03-25",{"date":235,"type":51},"2024-12-30",{"date":93,"type":21},{"name":238,"class":239},"Konya Beyhekim Training and Research Hospital","OTHER_GOV",{"id":241,"slug":242,"hasResults":11,"nctId":243,"briefTitle":244,"officialTitle":245,"acronym":4,"eligibilityCriteria":246,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":247,"targetDuration":4,"studyType":22,"phases":249,"briefSummary":250,"conditions":251,"keywords":4,"overallStatus":88,"whyStopped":4,"lastUpdateSubmitDate":253,"lastUpdatePostDateStruct":254,"startDateStruct":256,"completionDateStruct":258,"leadSponsor":260,"locationsCount":98},"100626807","home-based-physiotherapy-in-oncology-100626807","NCT07440433","Home-Based Physiotherapy in Oncology","Home-Based Physiotherapy for Oncology Patients: Feasibility and Acceptability of a Supervised Exercise Programme","Inclusion Criteria:\n\n* Age ≥ 18 years\n* Diagnosis of solid cancer, undergoing or recently completed treatment.\n* Overall survival greater than 12 months, as judged by the treating oncologist\n* Clinically stable and deemed fit for moderate exercise by the treating oncologist\n* Able to use an exercise bike\n* Home environment suitable for delivery and installation of the exercise bike\n* Able to understand the study language and follow study instructions\n* Able to give a written informed consent\n\nExclusion Criteria:\n\n* Medical contraindication to moderate exercise (e.g. uncontrolled cardiac or pulmonary disease, recent myocardial infarction, severe anemia or acute infection, unstable bone metastases or high fracture risk)\n* Cognitive impairment preventing active participation\n* Physical inability to perform the prescribed exercise programme, including cycling and resistance exercises.\n* Participation in another intensive rehabilitation program\n* Any other condition that, in the opinion of the treating oncologist or investigator, makes participation unsafe or not feasible\n* Pregnant or lactating women.",{"count":248,"type":21},21,[24],"The goal of this clinical trial is to assess the feasibility, acceptability, and safety of a supervised home-based physiotherapy programme for adult oncology patients. The programme combines aerobic cycling exercise, resistance training, and mental preparation strategies, delivered at home with regular professional supervision.\n\nThe main questions this study aims to answer are:\n\nIs a 6-month supervised home-based physiotherapy programme feasible in terms of recruitment, adherence, and retention?\n\nIs the programme safe for oncology patients undergoing or having recently completed cancer treatment?\n\nIs the programme acceptable and satisfactory from the patient's perspective?\n\nHow do physical function and health-related quality of life change over the course of the programme?\n\nThis is a single-arm feasibility study with no comparison group.\n\nParticipants will:\n\nReceive a stationary exercise bike delivered and installed at their home\n\nFollow a 6-month individualized physiotherapy programme including:\n\nThree weekly sessions combining moderate-intensity cycling and resistance exercises\n\nWear a connected activity watch during exercise sessions to monitor heart rate and exercise duration\n\nReceive weekly supervision from oncology-trained physiotherapists through alternating in-person hospital visits and structured phone calls\n\nComplete physical function assessments and questionnaires on quality of life, fatigue, and programme satisfaction at baseline, mid-program, and study completion\n\nThe results of this study will inform the design of a future larger controlled trial and contribute to the development of accessible home-based rehabilitation programmes for oncology patients.",[33,252],"Oncologic Diseases","2026-02-25",{"date":255,"type":51},"2026-02-27",{"date":257,"type":21},"2026-03",{"date":259,"type":21},"2028-03",{"name":261,"class":58},"University Hospital, Geneva",{"id":263,"slug":264,"hasResults":11,"nctId":265,"briefTitle":266,"officialTitle":266,"acronym":267,"eligibilityCriteria":268,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":190,"enrollmentInfo":269,"targetDuration":4,"studyType":22,"phases":271,"briefSummary":272,"conditions":273,"keywords":4,"overallStatus":47,"whyStopped":4,"lastUpdateSubmitDate":253,"lastUpdatePostDateStruct":277,"startDateStruct":278,"completionDateStruct":280,"leadSponsor":282,"locationsCount":98},"100600406","study-of-functional-magnetic-resonance-signal-variations-in-patients-undergoing-anterior-cruciate-ligament-reconstruction-with-the-application-of-a-dedicated-neuromotor-training-100600406","NCT07097077","Study of Functional Magnetic Resonance Signal Variations in Patients Undergoing Anterior Cruciate Ligament Reconstruction With the Application of a Dedicated Neuromotor Training","ACL-fMRI-TNMT","Inclusion Criteria:\n\n* Patients who have undergone anterior cruciate ligament reconstruction surgery at any healthcare facility\n* Able to understand and consent, adults, who have provided informed consent to participate in the study\n* Male or female\n* Age between 18 and 30 years at the time of signing the informed consent\n* Tegner activity level \\> 6\n\nExclusion Criteria:\n\n* History and\u002For evidence of any neurological disorder or functional impairment;\n* Evidence of previous surgeries on the lower limb;\n* Inability to provide informed consent;\n* Inability to perform the tasks required by the procedure;\n* Pregnant or breastfeeding women;\n* Oncology patients;\n* Contraindications to undergoing MRI examinations.",{"count":270,"type":21},12,[24],"Lower limb injuries represent the majority of sports-related injuries, with knee injuries being among the most common. In particular, anterior cruciate ligament (ACL) injuries are considered highly devastating and career-threatening for both professional and amateur athletes. Current surgical and rehabilitation treatments often fail to provide fully satisfactory short- and long-term outcomes. A very high risk of re-injury exists, especially in younger patients, with up to 35% experiencing a second ACL injury, alongside a significant long-term risk of early knee osteoarthritis.\n\nMost ACL injuries are non-contact or indirect contact injuries, implicating biomechanical factors and neuromuscular control as key determinants of injury mechanisms. Recent literature shows that patients suffering a non-contact ACL injury have a higher risk of re-injury compared to those with contact injuries, suggesting a significant cognitive component in injury processing, surgery, rehabilitation, and return to sport.\n\nRecent rehabilitation studies have introduced targeted neuromotor training designed to \"rebuild\" biomechanical and neuromuscular patterns to avoid mechanisms leading to re-injury. Movement quality tests are used post-training to confirm the reduction of risky biomechanical patterns, often resulting in a score indicating movement quality.\n\nGiven the brain's involvement in such injuries, pioneering studies have used functional magnetic resonance imaging (fMRI) to investigate changes in cortical brain areas following ACL injury and reconstruction. Evidence shows adaptations in both central and peripheral nervous systems, with altered sensorimotor cortex activation in patients during simple motor tasks, differing from healthy subjects. Prefrontal cortex alterations correlate with severe quadriceps muscle activation asymmetries, linking these brain patterns to post-injury return-to-sport outcomes.\n\nHowever, no studies have yet evaluated the interaction between cortical activation (neural compensations) measured by fMRI and outcomes from targeted neuromotor training during ACL rehabilitation. Understanding brain activation implications is crucial for developing large-scale rehabilitation protocols to reduce the risk of a second, potentially more devastating, knee injury.\n\nThis study aims to reveal whether a neuromotor training protocol can positively influence cognitive brain areas related to human movement, particularly by reducing risky injury patterns. It will be the first to test whether dedicated neuromuscular training effectively reduces neural compensations and cortical activation related to non-automated movement, favoring automation areas important for a safe return to sport.\n\nPatients will directly benefit from participating in the innovative neuromotor training program, with functional MRI scans conducted before training begins (post-surgery) and after training completion. Indirectly, the study will assess whether neuromotor training can adapt patient neuromotor patterns to reduce re-injury risk, ultimately benefiting future patients undergoing ACL reconstruction.",[274,275,33,276],"fMRI","ACL Injury","Neuromuscular Control",{"date":255,"type":51},{"date":279,"type":51},"2026-02-07",{"date":281,"type":21},"2027-07",{"name":283,"class":58},"Stefano Zaffagnini",{"id":285,"slug":286,"hasResults":11,"nctId":287,"briefTitle":288,"officialTitle":289,"acronym":4,"eligibilityCriteria":290,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":291,"targetDuration":4,"studyType":22,"phases":293,"briefSummary":294,"conditions":295,"keywords":4,"overallStatus":88,"whyStopped":4,"lastUpdateSubmitDate":298,"lastUpdatePostDateStruct":299,"startDateStruct":301,"completionDateStruct":303,"leadSponsor":305,"locationsCount":4},"100616852","effect-of-meditation-as-an-adjunct-to-cardiac-rehabilitation-100616852","NCT07310992","Effect of Meditation as an Adjunct to Cardiac Rehabilitation","The Effect of Meditation Practice Combined With Cardiac Rehabilitation on Improving Quality of Life and Controlling Blood Pressure.","Inclusion Criteria:\n\n* Patients of both sexes, aged 18 years or older.\n* Newly enrolled in the Phase II Cardiac Rehabilitation Program.\n* Clinically stable condition with medical clearance to perform aerobic and resistance exercises.\n* Diagnosis of cardiovascular disease (e.g., coronary artery disease, post-myocardial infarction, post-cardiac surgery, or stable heart failure) warranting rehabilitation.\n* Willingness and cognitive ability to provide written informed consent.\n* Availability to attend the twice-weekly sessions for the 12-week duration of the study.\n\nExclusion Criteria:\n\n* Current regular practice of meditation, yoga, or other mind-body techniques (defined as formal practice more than once a week in the previous 3 months).\n* Current participation in other psychological or behavioral intervention clinical trials.\n* Severe cognitive impairment or psychiatric disorders that preclude understanding of the meditation instructions or group participation (e.g., dementia, untreated psychosis).\n* Unstable clinical conditions such as unstable angina, uncontrolled arrhythmias, or decompensated heart failure that contraindicate physical exercise.\n* Significant orthopedic or neurological limitations that prevent the performance of the exercise protocol.\n* Refusal to participate in the randomization process.",{"count":292,"type":21},80,[24],"Cardiovascular rehabilitation is a well-established standard of care that significantly reduces morbidity and mortality while improving quality of life. However, integrating behavioral interventions into physical training may offer additional benefits for autonomic regulation and emotional well-being.\n\nThis randomized clinical trial aims to investigate the efficacy of adding a brief, guided mindfulness meditation session to a standard cardiovascular rehabilitation program. The study seeks to determine whether this combined intervention enhances blood pressure control, improves perceived quality of life, and increases patient adherence compared to standard rehabilitation alone.\n\nParticipants newly enrolled in the Cardiac Rehabilitation Service will be randomized into two groups. Both groups will undergo a standard 12-week regimen of aerobic and resistance training combined with optimized medical therapy. The intervention group will additionally receive 15 minutes of voice-guided mindfulness meditation at the end of each exercise session. Key outcome measures include blood pressure variability, quality of life scores (assessed via EQ-5D), and attendance rates.",[296,297,33],"High Blood Pressure (& [Essential Hypertension])","Meditation Training","2025-12-30",{"date":300,"type":51},"2026-01-05",{"date":302,"type":21},"2026-01-15",{"date":304,"type":21},"2028-01-15",{"name":306,"class":58},"Instituto Dante Pazzanese de Cardiologia",{"id":308,"slug":309,"hasResults":11,"nctId":310,"briefTitle":311,"officialTitle":311,"acronym":312,"eligibilityCriteria":313,"healthyVolunteers":11,"sex":17,"minAge":314,"maxAge":315,"enrollmentInfo":316,"targetDuration":4,"studyType":22,"phases":318,"briefSummary":319,"conditions":320,"keywords":321,"overallStatus":47,"whyStopped":4,"lastUpdateSubmitDate":326,"lastUpdatePostDateStruct":327,"startDateStruct":329,"completionDateStruct":331,"leadSponsor":333,"locationsCount":98},"100616421","the-musicare-project-effects-of-differentiated-music-exposure-on-exercise-related-affect-among-cardiac-rehabilitation-inpatients-100616421","NCT07305389","The MUSICare Project: Effects of Differentiated Music Exposure on Exercise-Related Affect Among Cardiac Rehabilitation Inpatients","MUSICare","Inclusion Criteria:\n\n* Individuals enrolled in an inpatient 3-week cardiac exercise-based rehabilitation programme\n* Age range 50-75 years\n* Can withstand the study protocol without undue risk\n* Able to provide written consent\n\nExclusion Criteria:\n\n* Contraindication to physical activity in view of the health status\n* Presence of cognitive or psychological disorder\n* Hearing impairment with or without hearing aids","50 Years","75 Years",{"count":317,"type":21},72,[24],"Affective phenomena, such as core affect, remembered pleasure, or forecasted pleasure, play a key role in promoting physical activity (PA) behaviour, especially among inpatients. The use of music has been shown to be a particularly cost-effective and low-friction approach to promoting positive affective valence during PA. However, interventions using music to improve exercise-related affective phenomena among inpatients are lacking. This study will aim to investigate an intervention that combines the effects of music with the \"peak-end rule\" on core affective responses (valence and arousal), remembered pleasure, and forecasted pleasure associated with exercise sessions among cardiac rehabilitation inpatients.\n\nThe primary objective of the present study will be to examine the effect of differentiated music exposure on core affective responses, ratings of perceived exertion and psychophysiological responses to moderate-intensity continuous training (MICT), as well as on associated remembered pleasure, exercise enjoyment, and forecasted pleasure. A secondary objective will be to assess the potential mediating effect of affective valence at the end of the MICT on remembered pleasure and exercise enjoyment. A third objective will be to assess the effect of MICT with or without music on an emotional rating task, together with pupillometric measures. Finally, the study will examine the influence of remembered pleasure on subsequent forecasted pleasure.",[33],[322,323,324,325],"cardiac rehabilitation","music","physical activity","affective valence","2025-12-12",{"date":328,"type":51},"2025-12-26",{"date":330,"type":51},"2024-09-01",{"date":332,"type":21},"2027-01-30",{"name":334,"class":58},"Elena Tessitore",{"id":336,"slug":337,"hasResults":11,"nctId":338,"briefTitle":339,"officialTitle":339,"acronym":340,"eligibilityCriteria":341,"healthyVolunteers":11,"sex":17,"minAge":4,"maxAge":315,"enrollmentInfo":342,"targetDuration":4,"studyType":22,"phases":344,"briefSummary":345,"conditions":346,"keywords":349,"overallStatus":88,"whyStopped":4,"lastUpdateSubmitDate":358,"lastUpdatePostDateStruct":359,"startDateStruct":361,"completionDateStruct":363,"leadSponsor":365,"locationsCount":98},"100612059","comprehensive-therapeutic-program-for-people-with-multiple-sclerosis-100612059","NCT07248657","Comprehensive Therapeutic Program For People With Multiple Sclerosis","BIB_MS","Inclusion criteria:\n\n* Confirmed clinical diagnosis of MS\n* Age ≤ 75 years\n* Predominantly motor impairment\n* EDSS 2-8\n* Ability and motivation to attend outpatient physiotherapy regularly\n\nExclusion criteria:\n\n• Contraindications such as severe orthopedic or cardiovascular dysfunction, or presence of another neurological disorder",{"count":343,"type":21},26,[24],"This study investigates the effectiveness of an intensive multidisciplinary rehabilitation program for people with multiple sclerosis (PwMS). The program integrates intensive outpatient physiotherapy, psychotherapeutic consultations, and nutritional counseling to enhance motor and cognitive functions, promote neuroplasticity, and improve overall well-being as well as physical performance in PwMS. Through clinical assessments and standardized questionnaires, the study aims to provide scientific evidence on the benefits of comprehensive, non-pharmacological therapy as a core element in MS treatment.",[347,348,76,33],"Multiple Sclerosis","Neurorehabilitation",[350,351,352,353,354,355,356,357],"multiple sclerosis","rehabilitation","physiotherapy","psychotherapy","psychological support","exercise","neurorehabilitation","facilitation and inhibition","2025-11-24",{"date":360,"type":51},"2025-12-01",{"date":362,"type":21},"2025-12-05",{"date":364,"type":21},"2026-12-31",{"name":366,"class":58},"Charles University, Czech Republic",{"id":368,"slug":369,"hasResults":11,"nctId":370,"briefTitle":371,"officialTitle":372,"acronym":373,"eligibilityCriteria":374,"healthyVolunteers":11,"sex":17,"minAge":375,"maxAge":376,"enrollmentInfo":377,"targetDuration":4,"studyType":22,"phases":379,"briefSummary":380,"conditions":381,"keywords":384,"overallStatus":88,"whyStopped":4,"lastUpdateSubmitDate":387,"lastUpdatePostDateStruct":388,"startDateStruct":390,"completionDateStruct":392,"leadSponsor":394,"locationsCount":4},"100596244","online-physical-activity-and-health-counseling-for-survivors-of-childhood-acute-lymphoblastic-leukemia-100596244","NCT07042932","Online Physical Activity and Health Counseling for Survivors of Childhood Acute Lymphoblastic Leukemia","Online Physical Activity and Health Counseling for Survivors of Childhood Acute Lymphoblastic Leukemia (OPAC-ALL)","OPAC-ALL","Inclusion Criteria:\n\n* aged 10-21 years old,\n* at least one year from ended treatment of acute lymphoplastic leukemia\n* not adhering to WHO's recommendations for physical activity (i.e., 60 minutes of daily moderate-to-vigorous intensity physical activity including two weekly sessions of strength training for children and 150 minutes of moderate-to-vigorous intensity weekly for adults),\n* followed at the pediatric oncology out-patient clinic at Copenhagen University Hospital, Rigshospitalet.\n\nExclusion Criteria:\n\n* Children with a mental disability,\n* other severe physical co-morbidity contradicting physical exercise,\n* and\u002For terminal illness","10 Years","21 Years",{"count":378,"type":21},82,[24],"Advances in the medical treatment of childhood acute lymphoblastic leukemia (ALL) have resulted in 5-year survival rates above 90%- however, the success is not without consequences. Childhood ALL survivors experience markedly impaired physical capacity - reducing their opportunity to engage in everyday activities including leisure activities, sports, and school - affecting their quality of life. Furthermore, Childhood ALL survivors have markedly increased risk of chronic medical conditions including cardiometabolic diseases - that can be prevented through an active lifestyle. Thus, it is imperative to develop novel interventions that can mitigate these treatment-related late-effects. In this RCT, including 82 childhood ALL survivors (10-21 years-old), we will investigate a 26-week online exercise intervention combined with access to a lifestyle physical activity webpage, and health consultations on cardiorespiratory fitness (primary outcome) markers of metabolic syndrome, and physical activity habits.\n\nWhile other pilot studies have investigated the effects of exercise for childhood ALL survivors, this study is the first RCT internationally to investigate the effects of online exercise combined with education through an app and health counselling for childhood ALL survivor. Using this approach, we are geographically able to reach every survivor in our targeted population, thereby, minimizing logistic challenges like travel distances.\n\nThis study has the potential to radically change the way physical rehabilitation is approached in childhood ALL survivors - Potentially changing the workflow of health professionals from referring only survivors with specific deficits to local physiotherapy to referring all survivors to an exercise program tailored to their needs. By improving the children's general physical capacity, we can give the children the required tools to re-enter everyday life activities, including school physical education, leisure activities, and sports earlier after treatment has ended - ultimately minimizing the social complications of treatment. This study will also answer the government´s call to digitalize 30% of rehabilitation by the 2030.",[382,383,114,33],"Acute Lymphoblastic Leukemia ALL","Childhood Cancer Survivors",[114,351,385,386],"Acute lymphoblastic leukemia","childhood cancer survivors","2025-06-25",{"date":389,"type":51},"2025-06-29",{"date":391,"type":21},"2025-07-01",{"date":393,"type":21},"2030-12-31",{"name":395,"class":58},"Rigshospitalet, Denmark",{"id":397,"slug":398,"hasResults":11,"nctId":399,"briefTitle":400,"officialTitle":401,"acronym":402,"eligibilityCriteria":403,"healthyVolunteers":11,"sex":404,"minAge":18,"maxAge":4,"enrollmentInfo":405,"targetDuration":4,"studyType":218,"phases":4,"briefSummary":407,"conditions":408,"keywords":412,"overallStatus":88,"whyStopped":4,"lastUpdateSubmitDate":416,"lastUpdatePostDateStruct":417,"startDateStruct":419,"completionDateStruct":421,"leadSponsor":423,"locationsCount":4},"100578727","state-of-play-of-physiotherapy-in-the-postoperative-management-of-prostate-cancer--prospective-monocentric-national-survey-aiming-to-explore-the-technics-of-physiotherapy-predukin-100578727","NCT06815055","State of Play of Physiotherapy in the Postoperative Management of Prostate Cancer : Prospective, Monocentric, National Survey, Aiming to Explore the Technics of Physiotherapy (PREduKiné)","PREduKiné State of Play of Physiotherapy in the Postoperative Management of Prostate Cancer : Prospective, Monocentric, National Survey, Aiming to Explore the Technics of Physiotherapy","PREduKiné","Inclusion Criteria:\n\n* men who has undergone a radical prostactectomy to treat a prostatic adenocarcinoma\n* having a follow up postoperative consultation between one and two month after the surgery\n* being able to answer to respond the questions during the interviews\n* agreeing to participate by signing informed consent form\n\nExclusion Criteria:\n\n* undergoing an adjuvant therapy as radiotherpy, chemotherapy and hormone therapy\n* Refusing to take part in the study","MALE",{"count":406,"type":21},510,"In France, a considerable number of radical prostactectomy for cancer is carried out every year.This number was estimated at 20.000 in 2016.This surgery may have negative impact on the continence's subjects and their quality of life. The rehabilitation, preoperative or postoperative, practiced by a physiotherapist, can reduced those side effects. The rehabilitation techniques are many and their efficacy may differ.\n\nNo study where found about the clasification and evaluation of those rehabilitation techniques.",[409,80,410,411,33],"Radical Prostatectomies","Prostate Cancer","Prostate Cancer Surgery",[413,351,414,415],"radical prostatectomy","continence","quality of life","2025-06-02",{"date":418,"type":51},"2025-06-05",{"date":420,"type":21},"2025-06-01",{"date":422,"type":21},"2026-12-30",{"name":424,"class":58},"Centre Hospitalier de Roubaix",{"id":426,"slug":427,"hasResults":11,"nctId":428,"briefTitle":429,"officialTitle":429,"acronym":4,"eligibilityCriteria":430,"healthyVolunteers":68,"sex":17,"minAge":376,"maxAge":164,"enrollmentInfo":431,"targetDuration":4,"studyType":22,"phases":433,"briefSummary":434,"conditions":435,"keywords":4,"overallStatus":88,"whyStopped":4,"lastUpdateSubmitDate":436,"lastUpdatePostDateStruct":437,"startDateStruct":439,"completionDateStruct":440,"leadSponsor":442,"locationsCount":98},"100590691","programmable-smart-watch-for-remote-pre-habilitationrehabilitation-monitoring-100590691","NCT06970717","Programmable Smart Watch for Remote Pre-habilitation\u002FRehabilitation Monitoring","Inclusion Criteria:\n\n1. Age 21-60\n2. Not on follow up for chronic diseases\n3. Willing to perform exercises daily x 5 days\n4. Able to handle simple technology eg. smart phone\n\nExclusion Criteria:\n\n1. Pregnant women\n2. Active joint pains and any other musculoskeletal issues\n3. Heart conditions or balance issues",{"count":432,"type":21},20,[24],"The purpose of this research study is to validate the M5Stick Programmable watch as a prototype to monitor specific prehabilitation exercises and to monitor the frequency of exercises and the number of repetitions the subject makes in a home setting.",[33],"2025-05-06",{"date":438,"type":51},"2025-05-14",{"date":420,"type":21},{"date":441,"type":21},"2026-08-31",{"name":443,"class":58},"Changi General Hospital"]