[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"rehabilitation-program\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:rehabilitation-program":29},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,5,0,[8,49,82,113,136],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":32,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":38,"lastUpdatePostDateStruct":39,"startDateStruct":42,"completionDateStruct":44,"leadSponsor":46,"locationsCount":4},"100641331","digitally-assisted-rehabilitation-at-home-for-older-adults-after-hip-surgery-grimsel-100641331",false,"NCT07658664","Digitally Assisted Rehabilitation at Home for Older Adults After Hip Surgery (GRIMSEL)","Digitally Assisted Geriatric Home-rehabilitation in Older Patients After Hip Surgery (GRIMSEL): a Non-inferiority Randomized Controlled Trial","GRIMSEL","Inclusion Criteria:\n\n* Community-dwelling adults aged 55 to 80 years\n* Hospitalized for hip surgery with unrestricted weight bearing at University Hospital Bern\n\nExclusion Criteria:\n\n* Discharge to inpatient rehabilitation\n* inability to comply with a rehabilitation program (e.g. comorbidity that prevents 30min light workout, major cognitive impairment)\n* end-of life situation","ALL","55 Years","80 Years",{"count":21,"type":22},66,"ESTIMATED","INTERVENTIONAL",[25],"NA","The goal of this clinical trial is to learn if a 12-week digitally supported, multimodal home rehabilitation program using the medical application Akina is as effective compared to routine care regarding functional independence in older adults undergoing hip surgery.\n\nHow is this multimodal home rehabilitation program received by patients? Is this multimodal home program at least as effective in terms of functional indpendence, muscle status, mobility and quality of life compared to routine care?\n\nResearchers will compare the multimodal rehabilitation program using the application Akina to routine care to see if the program works to treat patients after hip surgery.\n\nParticipants will:\n\nUndergo the rehab program at home or receive routine care (outpatient physiotherapy) for 12 weeks Visit the clinic after 6 and 12 weeks",[28,29,30,31],"Hip Surgery","Rehabilitation Program","Geriatrics Rehabilitation","Digital Health Intervention",[33,34,35,36],"functional independence","home-based rehabilitation","self-management","orthogeriatrics","NOT_YET_RECRUITING","2026-06-16",{"date":40,"type":41},"2026-06-22","ACTUAL",{"date":43,"type":22},"2026-08",{"date":45,"type":22},"2028-08",{"name":47,"class":48},"Insel Gruppe AG, University Hospital Bern","OTHER",{"id":50,"slug":51,"hasResults":11,"nctId":52,"briefTitle":53,"officialTitle":54,"acronym":4,"eligibilityCriteria":55,"healthyVolunteers":11,"sex":17,"minAge":56,"maxAge":4,"enrollmentInfo":57,"targetDuration":4,"studyType":23,"phases":59,"briefSummary":60,"conditions":61,"keywords":65,"overallStatus":72,"whyStopped":4,"lastUpdateSubmitDate":73,"lastUpdatePostDateStruct":74,"startDateStruct":76,"completionDateStruct":78,"leadSponsor":80,"locationsCount":5},"100580365","registry-randomized-comparison-of-rehabilitation-regimens-after-flexor-tendon-injury-in-the-thumb-100580365","NCT06836349","Registry-randomized Comparison of Rehabilitation Regimens After Flexor Tendon Injury in the Thumb","Registry-randomized Comparison of Rehabilitation Regimens After Flexor Pollicis Longus Injury in the Thumb","Inclusion Criteria:\n\nComplete laceration of the thumb flexor tendon (Flexor Pollicis Longus; FPL) within zone 1 and 2.\n\nAge over 15 years. Minors (\\\u003C18 years) are considered to have sufficient maturity to understand the implications of the research.\n\nSwedish-speaking \u002F able to understand spoken and written Swedish. Surgery performed within 14 days from the time of injury.\n\nExclusion Criteria:\n\nTendon injury with a defect requiring tendon grafting. Another complete tendon injury in the same hand. Extensive associated injuries, such as fracture, vascular injury with circulatory impairment, large skin defect, or preoperative signs of infection. Patient deemed unsuitable for early active motion therapy due to factors such as lack of cooperation, cognitive impairment, or substance abuse issues.\n\nPatient declines follow-up in the HAKIR quality registry. Wound infection making early active motion therapy inappropriate.","15 Years",{"count":58,"type":22},380,[25],"Flexor tendon injuries in the thumb occur across all ages and genders. Each year, approximately 400 patients undergo surgery for a flexor tendon injury in Sweden. These injuries are exclusively treated at one of the seven specialized hand surgery clinics, as the surgery is technically demanding, and postoperative rehabilitation is critical, specialized, and requires expertise from hand therapists. To prevent tendon adhesions and stiffness in the thumb or fingers, controlled active motion therapy is usually initiated within a few days after surgery. Studies on finger flexor tendon injuries have shown that early active movement therapy leads to better mobility compared to immobilization. Consequently, early active training is now the standard treatment following flexor tendon repair. However, during postoperative rehabilitation, the repaired flexor tendon may rupture, often necessitating revision surgery.\n\nThe rupture rate after flexor tendon repair in the thumb is approximately three times higher than in other fingers (10% vs. 3%). While most studies on flexor tendon injuries focus on finger tendons, research on the outcomes of thumb flexor tendon injuries is limited. The biomechanics and anatomy of the thumb's flexor tendon differ significantly from those of finger tendons.\n\nThe objective of this study is to determine whether the rupture rate following thumb flexor tendon surgery can be reduced by immobilizing the thumb in a cast for four weeks postoperatively, compared to standard early active motion therapy, without negatively affecting joint mobility and thumb strength. Additionally, the study will evaluate patient-reported outcomes one year post-surgery for both rehabilitation regimens (immobilization vs. mobilization).\n\nThis study is a registry-randomized clinical trial (RRCT) involving five hand surgery clinics in Sweden. Data following randomization between the two rehabilitation protocols will be collected through follow-up in the Swedish National Hand Surgery Quality Registry (HAKIR).",[62,29,63,64],"Flexor Tendon Injury","Flexor Tendon Rupture","Thumb Injury",[66,67,68,69,70,71],"Flexor pollicis longus injury","RRCT","Early active motion","flexor tendon injury","Thumb","Immobilisation","RECRUITING","2026-05-31",{"date":75,"type":41},"2026-06-03",{"date":77,"type":41},"2025-05-01",{"date":79,"type":22},"2031-12-31",{"name":81,"class":48},"Karolinska Institutet",{"id":83,"slug":84,"hasResults":11,"nctId":85,"briefTitle":86,"officialTitle":87,"acronym":88,"eligibilityCriteria":89,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":90,"enrollmentInfo":91,"targetDuration":4,"studyType":23,"phases":93,"briefSummary":94,"conditions":95,"keywords":99,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":103,"lastUpdatePostDateStruct":104,"startDateStruct":106,"completionDateStruct":108,"leadSponsor":110,"locationsCount":112},"100633113","enhancing-attention-and-processing-speed-through-home-based-music-rehabilitation-program-after-stroke-in-malaysia-100633113","NCT07522463","Enhancing Attention and Processing Speed Through Home-based Music Rehabilitation Program After Stroke in Malaysia","Enhancing Attention and Processing Speed Through Home-based Music Rehabilitation Program After Stroke in Malaysia: A Feasibility Random Controlled Study","HMRPAS","Inclusion Criteria:\n\n* Diagnosed with ischemic or haemorrhagic stroke confirmed by CT scan\n* 18 to 70 years old\n* Duration of stroke within the first one year\n* Ability to provide informed consent\n* Understands Bahasa Melayu or English with basic communication abilities to follow instructions during therapy sessions\n* Mild to moderate cognitive impairments with MoCA score of 10-25, with incomplete score for the attention sections\n* Availability of caregiver (formal or informal) who can assist in the music therapy, monitor and give feedback during the music therapy sessions at home\n* Have one normal functioning hand to perform the movements during the music therapy rehabilitation program\n* Have good balance and able to sit upright\n\nExclusion Criteria:\n\n* Severe aphasia\n* Significant uncorrected hearing or visual impairments preventing engagement in music therapy.\n* Severe or unstable medical conditions (e.g., uncontrolled hypertension or diabetes).\n* Medications that significantly impair cognition or motor function (e.g., high-dose sedatives).\n* History of neurological diseases other than stroke (eg, Parkinson's disease).","75 Years",{"count":92,"type":22},36,[25],"Stroke often leads to significant cognitive impairment, impacting quality of life. While existing rehabilitation options exist, there's a need for innovative, accessible, and patient-centered solutions. Research suggests music can engage multiple brain networks associated with sensory and motor processes, cognition, and affective regulation, potentially enhancing cognitive functions like attention and processing speed as well. Home-based interventions have also demonstrated positive impacts on rehabilitation adherence and outcomes. Building on this foundation, this study proposes to develop and pilot test a home-based musical rehabilitation program to improve attention and processing speed in Malaysian stroke survivors.",[96,97,29,98],"Stroke","Attention","Music Intervention",[97,100,101,96,102],"Processing Speed","Home-based Music Rehabilitation Program","Malaysia","2026-04-07",{"date":105,"type":41},"2026-04-13",{"date":107,"type":22},"2026-04-01",{"date":109,"type":22},"2026-10-31",{"name":111,"class":48},"University of Malaya",1,{"id":114,"slug":115,"hasResults":11,"nctId":116,"briefTitle":117,"officialTitle":117,"acronym":4,"eligibilityCriteria":118,"healthyVolunteers":11,"sex":17,"minAge":119,"maxAge":4,"enrollmentInfo":120,"targetDuration":4,"studyType":23,"phases":122,"briefSummary":123,"conditions":124,"keywords":4,"overallStatus":72,"whyStopped":4,"lastUpdateSubmitDate":127,"lastUpdatePostDateStruct":128,"startDateStruct":130,"completionDateStruct":132,"leadSponsor":134,"locationsCount":112},"100624721","benefits-of-a-renal-rehabilitation-program-adapted-to-uremic-patients-on-daily-hemodialysis-at-low-dialysate-flow-rate-100624721","NCT07413315","Benefits of a Renal Rehabilitation Program Adapted to Uremic Patients on Daily Hemodialysis at Low Dialysate Flow Rate.","Inclusion Criteria:\n\n* patient with terminal chronic kidney disease requiring hemodialysis treatment\n* patient recently hospitalized for an acute medical event.\n\nExclusion Criteria:\n\n* dementia\u002Fmild cognitive impairment (MMSE \\\u003C 20\u002F30)\n* decompensated psychiatric pathology and\u002For behavioral disorders\n* pregnant woman\n* recovery of renal function allowing interruption of helodialysis sessions\n* candidate for neurological rehabilitation\n* patient with recent spinal cord injury\n* patient with absolute and\u002For relative contraindication to performing a stress test\n* severe or poorly tolerated cardiac rhythm disorder\n* severe or symptomatic obstruction to left ventricular ejection\n* decompensated heart failure\n* acute myocarditis, pericarditis or endocarditis\n* acute aortic dissection\n* high-risk emboligenic intracardiac thrombus\n* significant stenosis of the common trunk\n* ventricular aneurysm\n* supraventricular tachycardia with poorly controlled ventricular rate, acquired high-degree or complete block\n* obstructive cardiomyopathy with high resting gradient\n* recent stroke or TIA\n* acute venous thrombosis with or without pulmonary embolism\n* poorly controlled clinical condition, such as marked anemia, significant electrolyte disturbance, hyperthyroidism, etc.\n* lack of cooperation from the patient\n* Blood pressure \\> 200\u002F110 mmHg","18 Years",{"count":121,"type":22},50,[25],"The concept of renal rehabilitation has become increasingly important with the increasing age of patients with severe or even terminal chronic kidney disease (CKD). It combines physical exercise and nutritional monitoring programs for patients with terminal CKD who are most often treated with conventional hemodialysis (HD) at a rate of 3 sessions of 4 hours per week.\n\nSarcopenia is a very common phenomenon in patients with CKD. The prevalence found in recent meta-analyses varies between 25.6 and 28.5% in patients treated with dialysis. It is even higher in patients treated with HD than in patients treated with peritoneal dialysis (PD). Younger and more active patients will more often choose PD. The conventional HD modality preserves residual renal function less well, which is important for better elimination of uremic toxins bound to plasma proteins. Conventional HD requires a higher immobilization time and causes more post-dialysis symptoms, leaving less time for the patient to be physically active.\n\nThe phenomenon of sarcopenia is not insignificant. It is associated in dialysis patients with a higher mortality rate (risk x 1.8) and a higher incidence of cardiovascular events (risk x 3.8). The association with higher mortality is well demonstrated for the 2 main components of sarcopenia, namely reduced muscle mass and reduced muscle strength. Sarcopenia also increases the risk of falls and fractures, it decreases the physical performance of patients and their ability to perform activities of daily living. The quality of life of patients is reduced and the probability of social placement is high.\n\nThe phenomena of sarcopenia and physical deconditioning are even more problematic in patients in HD after an acute medical problem. The need for rehabilitation is even higher. \"Classical\" HD treatment can be a burden for these patients, leaving no room for integrating a complete rehabilitation program.\n\nDaily low dialysate flow rate hemodialysis (LDF) is a type of hemodialysis in which patients benefit from more frequent but shorter and hemodynamically better tolerated HD sessions. This new technique potentially presents certain advantages over conventional HD, particularly at the cardiovascular level: better blood pressure control and better reduction of left ventricular hypertrophy. LDF also allows better control of hyperphosphatemia with a reduced need for phosphorus binders. Thanks to more frequent dialysis (5 to 6 sessions per week), inter-dialytic weight gain is often less significant, allowing less aggressive ultrafiltration, with better hemodynamic tolerance, and better post-dialysis recovery. In this perspective, this study aims to examine the interest of integrating HDQ dialysis into a renal rehabilitation program in patients with terminal CKD whose dialysis must continue after an acute event requiring hospitalization. The investigators want to study whether this technique allows the implementation of a more effective rehabilitation program, while maintaining the same dialysis efficiency as with the conventional HD technique. To the investigator's knowledge, no study concerning patients under HDQ has been conducted during their renal rehabilitation phase.\n\nThe objectives of the current study are:\n\n* To study the interest of integrating HDQ dialysis into a renal rehabilitation program in patients with terminal CKD.\n* To study the efficacy and tolerance of HDQ dialysis and the rehabilitation program in these patients.",[125,126,29],"Chronic Kidney Disease Requiring Hemodialysis","Sarcopenia","2026-02-09",{"date":129,"type":41},"2026-02-17",{"date":131,"type":41},"2024-08-13",{"date":133,"type":22},"2027-12-31",{"name":135,"class":48},"Brugmann University Hospital",{"id":137,"slug":138,"hasResults":11,"nctId":139,"briefTitle":140,"officialTitle":141,"acronym":142,"eligibilityCriteria":143,"healthyVolunteers":11,"sex":17,"minAge":144,"maxAge":4,"enrollmentInfo":145,"targetDuration":4,"studyType":23,"phases":147,"briefSummary":148,"conditions":149,"keywords":151,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":154,"lastUpdatePostDateStruct":155,"startDateStruct":157,"completionDateStruct":159,"leadSponsor":161,"locationsCount":163},"100591415","rehabilitation-in-the-home-after-hip-fracture-100591415","NCT06980129","Rehabilitation in the Home After Hip Fracture","RITH4Hips - Rehabilitation in the Home After Hip Fracture","RITH4Hips","Inclusion Criteria:\n\n* Community-dwelling adults ages ≥ 50 years presenting to Liverpool hospital or Bankstown-Lidcombe hospital with a low-trauma (osteoporotic) hip fracture who undergo surgical management\n* Anticipated to return to community (private) residence\n* Permitted to weight-bear as tolerated post-surgery\n* Suitable for inpatient rehabilitation (i.e., requires multidisciplinary rehabilitation, is considered cognitively suitable by the MDT to participate in the rehabilitation program being examined, and would otherwise be admitted to inpatient rehabilitation)\n* The presence of a carer, if required for mobility or function, is necessary at the time of transfer to the community. The carer must be prepared to manage the patient within 3 days post-randomisation. This time frame is considered necessary as carers will not be able to complete all required preparations before randomisation, and allowing an extended preparation period could bias the length of physical ward bed stay for the RITH group\n* Suitable environment for home-based rehabilitation as assessed by the MDT as per usual practice\n\nExclusion Criteria:\n\n* Presence of a concomitant condition that precludes actively participating in a rehabilitation program at home\n* Residential location outside the Bankstown-Canterbury, Liverpool, and Fairfield Local Government Areas\n* Active end-of-life management or palliative care\n* Previously participated in the HITH4Hips or RITH4Hips trials","50 Years",{"count":146,"type":22},220,[25],"Hip fractures are common, especially in older adults, and they can have a big impact on health and quality of life. In Australia, hip fractures are a significant healthcare challenge. After surgery, patients often need rehabilitation to regain mobility, but this usually involves long hospital stays. The RITH4Hips trial will determine if a program where patients receive rehabilitation at home (instead of in the hospital) is similar to conventional inpatient rehabilitation.\n\nObjectives:\n\nThe main goal of this study is to find out if rehabilitation at home after surgery for a hip fracture works as well as rehabilitation in the hospital. The investigators also want to see if the home rehabilitation program can reduce the time spent in a hospital bed and improve other aspects like quality of life, mobility, and pain management.\n\nMethods:\n\nThis study will involve older adults who have had surgery due to a low-trauma hip fracture. Participants will be randomly assigned to either the usual care inpatient rehabilitation or the Rehabilitation in the Home (RITH) program. The investigators will measure outcomes such as how well patients can move, how much pain they experience, how their quality of life improves, and how much time they spend in the hospital.\n\nExpected Outcomes:\n\nThe investigators expect that the home rehabilitation program will be just similar to inpatient rehabilitation in helping patients recover mobility. The investigators also hope to find that it will reduce the time patients spend in a hospital bed, improve their quality of life, reduce fear of falling, and lessen the burden on carers. Additionally, the investigators aim to show that the home program is more cost-effective than hospital-based rehabilitation.",[150,29],"Hip Fractures (ICD-10 72.01-72.2)",[152,153],"rehabilitation program","hip fracture","2025-05-11",{"date":156,"type":41},"2025-05-20",{"date":158,"type":22},"2025-06-01",{"date":160,"type":22},"2027-09-20",{"name":162,"class":48},"South West Sydney Local Health District",3]