[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"relatives\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:relatives":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,47,75],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":15,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":28,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":35,"lastUpdatePostDateStruct":36,"startDateStruct":39,"completionDateStruct":41,"leadSponsor":43,"locationsCount":46},"100559387","pegasus---improving-treatment-for-patients-with-emotionally-unstable-personality-disorder-100559387",false,"NCT06563466","PEGASUS - Improving Treatment for Patients With Emotionally Unstable Personality Disorder","Participating Patients\n\nInclusion Criteria:\n\n* Must be able to give an informed written consent.\n* Must be newly accepted in the pre-planned BPD treatment packages.\n* ≥18 years of age.\n* Agreeing to involvement of one or two informal caregivers, families, or close friends (\"Relatives\").\n* Capable of reading and understanding Danish.\n\nExclusion Criteria:\n\n* None\\*\n\n  * Note that to get accepted into a treatment package for BPD, patients must not fulfill the criteria for a F20 diagnosis or the criteria for alcohol or substance abuse or harmful use.\n\nParticipating Relatives:\n\nInclusion Criteria:\n\n* Must be able to give an informed written consent.\n* ≥18 years of age.\n* Capable of reading and understanding Danish.\n\nExclusion criteria: None",true,"ALL","18 Years",{"count":19,"type":20},100,"ESTIMATED","INTERVENTIONAL",[23],"NA","The purpose of the PEGASUS study is to conduct a pilot trial to test the feasibility and acceptability of the PEGASUS intervention, adding a case manager and family-based interventions meetings to the existing psychiatric integrated care-models known as \"Treatment Packages\" in Denmark. We will conduct a randomized, assessor-blinded parallel-groups superiority clinical trial, testing the PEGASUS intervention for emotionally unstable personality disorder \"EUPD\", borderline type (borderline personality disorder) compared to \"Treatment as Usual\" before moving on to testing in a full-scale trial. Participants will be assessed at baseline and 9 month post baseline at study conclusion",[26,27],"Borderline Personality Disorder","Relatives",[26,27,29,30,31,32,33],"Group psychotherapy","Case management","Psychoeducation","Family","Caregiver","RECRUITING","2026-04-22",{"date":37,"type":38},"2026-04-28","ACTUAL",{"date":40,"type":38},"2024-09-01",{"date":42,"type":20},"2029-08-31",{"name":44,"class":45},"University Hospital Bispebjerg and Frederiksberg","OTHER",1,{"id":48,"slug":49,"hasResults":11,"nctId":50,"briefTitle":51,"officialTitle":52,"acronym":4,"eligibilityCriteria":53,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":54,"targetDuration":4,"studyType":56,"phases":4,"briefSummary":57,"conditions":58,"keywords":62,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":66,"lastUpdatePostDateStruct":67,"startDateStruct":69,"completionDateStruct":71,"leadSponsor":73,"locationsCount":46},"100575320","family-involvement-in-icu-100575320","NCT06770751","Family Involvement in ICU","Family Involvement in the Intensive Care Unit: a Prospective Cohort Study Exploring Its Effects on Sedation Dosages, Delirium, Ventilator-Free Days, and Length of Stay.","Inclusion Criteria:\n\n* Patients aged 18 and over.\n* Patients with at least one family member actively involved in the care process in the ICU.\n\nExclusion Criteria:\n\n* Patients with pre-existing cognitive impairment or dementia.\n* Patients with severe traumatic brain injury.\n* Patients with an expected mortality in the ICU of more than 80%.\n* Absence of family members for patients admitted to the ICU.",{"count":55,"type":20},122,"OBSERVATIONAL","The aim of this prospective cohort study was to investigate the effect of the time spent with relatives of patients treated in a tertiary intensive care unit on patient outcomes.\n\nThe main question it aimed to answer was:\n\nDoes spending more time with relatives of patients in intensive care result in lower sedative agent requirements? Does spending more time with relatives of patients in intensive care result in less delirium, fewer ventilator days, and shorter ICU stays?",[59,27,60,61,32],"Intensive Care Patients","Delirium in the Intensive Care Unit","Sedatives",[63,64,65,61],"Intensive care patients","relatives","Delirium in the intensive care unit","2025-01-15",{"date":68,"type":38},"2025-01-17",{"date":70,"type":38},"2025-01-13",{"date":72,"type":20},"2025-08-15",{"name":74,"class":45},"Istanbul University - Cerrahpasa",{"id":76,"slug":77,"hasResults":11,"nctId":78,"briefTitle":79,"officialTitle":80,"acronym":81,"eligibilityCriteria":82,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":83,"targetDuration":4,"studyType":56,"phases":4,"briefSummary":85,"conditions":86,"keywords":4,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":93,"lastUpdatePostDateStruct":94,"startDateStruct":96,"completionDateStruct":98,"leadSponsor":100,"locationsCount":102},"100523843","patient-reported-outcome-and-patient-reported-experience-after-status-epilepticus-100523843","NCT06100978","Patient-reported Outcome and Patient-reported Experience After Status Epilepticus","Patient-reported Outcomes in Status Epilepticus Requiring Intensive Care Unit Management. A Multicenter Longitudinal Cohort Study","POSEIDON2","Inclusion Criteria:\n\n* Adults 18 years old or older\n* Patients previously included in the ICTAL registry (Status Epilepticus cohort NCT03457831)\n* Survivors after ICU management for Status Epilepticus More than 3 months and less than 5 years after ICU discharge\n\nExclusion Criteria:\n\n* Legal guardianship\n* Opposition to participate\n* Unread and unwritten French language\n* Patient not affiliated to a Social Security system",{"count":84,"type":20},145,"Status epilepticus (SE) is a common life-threatening neurological emergency in which prolonged or multiple closely spaced seizures can result in long-term impairments. SE remains associated with considerable mortality and morbidity, with little progress over the last three decades. The proportion of patients who die in the hospital is about 20% overall and 40% in patients with refractory SE. Morbidity is more difficult to evaluate, as adverse effects of SE are often difficult to differentiate from those attributed to the cause of SE. Our experience suggests that nearly 50% of patients may experience long-term functional impairments. The precise description of the consequences of these functional impairments and their impact on quality of life after SE requiring intensive care management has been little studied. Indeed, if cognitive, physical and mental impairments are now identified in the populations of patients who required intensive care under the term postresuscitation syndrome (PICS), neuronal lesions consecutive to the SE itselfor to its cause could be responsible for these different functional alterations.\n\nThus, the following have been described: (i) cognitive disorders in the areas of attention, executive functions and verbal fluency, visual and working memory disorders, but also spatio-temporal disorders; (ii) physical disorders such as the so-called post-resuscitation polyneuromyopathy; and (iii) mental disorders such as anxiety disorders, depressive states or those related to post-traumatic stress.\n\nAssessment and characterization of patient-reported outcomes is essential to complement the holistic assessment of clinically relevant outcomes from the patient's perspective. The POSEIDON study was a cross-sectional collection of PROs and HR-QOL components, and associated with patient functional outcomes, in those who required ICU management for status epilepticus. We propose here to continue the description of potential alterations after a subsequent ME, namely a longitudinal study (POSEIDON 2) which will also include the evaluation of patient-reported experience (PREMS) and the measurement of family burden.",[87,88,89,90,91,92,27],"Patient Reported Outcomes","Patient Satisfaction","Long Term Outcomes","Status Epilepticus","Intensive Care Unit","Burden","2024-11-04",{"date":95,"type":38},"2024-11-05",{"date":97,"type":38},"2024-05-25",{"date":99,"type":20},"2026-07",{"name":101,"class":45},"Versailles Hospital",13]