[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"reminiscence-therapy\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:reminiscence-therapy":30},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,44],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":14,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":4,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":32,"lastUpdatePostDateStruct":33,"startDateStruct":36,"completionDateStruct":38,"leadSponsor":40,"locationsCount":43},"100631353","multi-modal-large-language-model-empowered-talk-therapy-for-older-adults-with-adrd-100631353",false,"NCT07499570","Multi-modal Large Language Model-Empowered Talk Therapy for Older Adults With ADRD","SVR","For the patient:\n\nInclusion criteria:\n\n* age ≥ 65 years\n* diagnosis of MCI (mild cognitive impairment) or mild ADRD\n* access to a reliable internet connection\n* community-dwelling\n* elevated behavioral and psychological symptoms of dementia (BPSD), indicated by a HABC (Healthy Aging Brain Care) monitor score above 14 on caregiver report or self report (indicating elevated levels of BPSD)\n* presence of one or more specific BPSD behaviors (e.g., agitation, anxiety, depression, apathy, or sleep disturbances)\n* ability to consent for themselves.\n\nExclusion criteria:\n\n* lives in an assisted living facility or nursing home\n* has moderate to severe ADRD as measured by the Quick Dementia Rating System\n* has a life expectancy of less than 6 months.\n\nFor the care partner:\n\nInclusion criteria:\n\n* ≥ 21 years old\n* self-identified care partner (e.g., is knowledgeable about the patient's daytime and nighttime behaviors) of a community-dwelling patient diagnosed with MCI or mild ADRD who will also participate in the study\n\nExclusion criteria:\n\n* has MCI or dementia\n* has a severe mental illness or substance abuse\n* has a life expectancy of less than 6 months.","ALL","65 Years",{"count":19,"type":20},60,"ESTIMATED","INTERVENTIONAL",[23],"NA","The purpose of this study is to test the usefulness and the effect of Smart Virtual Reminiscence (SVR) therapy intervention on the Behavioral and Psychological Symptoms of Dementia (BPSD) of patients with Alzheimer's Disease and Related Dementias (ADRD).\n\nSVR is designed to help older adults improve their psychological well-being and cognition. This research supports our long-term goal of designing and implementing intelligent interactive systems to improve the health of individuals with ADRD.",[26,27,28,29,30],"Mild Cognitive Impairment","Dementia","BPSD","BPSD (Behavioral and Psychological Symptoms of Dementia)","Reminiscence Therapy","RECRUITING","2026-05-01",{"date":34,"type":35},"2026-05-06","ACTUAL",{"date":37,"type":35},"2025-09-03",{"date":39,"type":20},"2027-03-01",{"name":41,"class":42},"Indiana University","OTHER",1,{"id":45,"slug":46,"hasResults":11,"nctId":47,"briefTitle":48,"officialTitle":49,"acronym":50,"eligibilityCriteria":51,"healthyVolunteers":11,"sex":16,"minAge":52,"maxAge":4,"enrollmentInfo":53,"targetDuration":4,"studyType":21,"phases":55,"briefSummary":56,"conditions":57,"keywords":60,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":62,"lastUpdatePostDateStruct":63,"startDateStruct":65,"completionDateStruct":67,"leadSponsor":69,"locationsCount":43},"100586724","a-virtual-life-story-club-intervention-to-improve-loneliness-and-apathy-in-community-dwelling-older-adults-100586724","NCT06919094","A Virtual Life Story Club Intervention to Improve Loneliness and Apathy in Community-Dwelling Older Adults","A Virtual Life Story Club Intervention to Improve Loneliness and Apathy in Community-Dwelling Older Adults: A Mixed-Methods Feasibility Study","LSC Feasible","Inclusion Criteria:\n\n* Age 60 and over\n* English or Spanish fluency\n* Able to provide informed consent\n\nExclusion Criteria:\n\n* Dementia based on Aging and Dementia (AD8) score of ≥4 or previous dementia diagnosis\n* Severe auditory or visual loss\n* Lack of access to internet connection or phone","60 Years",{"count":54,"type":20},50,[23],"Reminiscence therapy is a non-invasive, non-pharmacological intervention that has been shown to improve cognition, mood, functional status, quality of life, and apathy in older adults. Group reminiscence therapy combines structured social engagement and recounting of personal stories that address both social connection (a risk factor for cognitive decline) and cognition. Life story club© (LSC) is an established, non-profit organization that provides virtual, group reminiscence therapy for older adults to reduce loneliness and promote a sense of belonging and has not been formally studied.",[58,59,30],"Apathy","Loneliness",[58,61,59,30],"Social Isolation","2025-12-17",{"date":64,"type":35},"2025-12-19",{"date":66,"type":35},"2025-08-15",{"date":68,"type":20},"2026-08-31",{"name":70,"class":42},"Montefiore Medical Center"]