[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"renal-stone\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:renal-stone":29},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,8,0,[8,47,79,106,127,147,168,189],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":30,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":36,"lastUpdatePostDateStruct":37,"startDateStruct":40,"completionDateStruct":42,"leadSponsor":44,"locationsCount":4},"100643028","fragmentation-vs-dusting-with-fans-for-renal-stones-less-than-2cm-a-randomized-controlled-study-100643028",false,"NCT07639385","Fragmentation Vs Dusting With FANS for Renal Stones Less Than 2cm: A Randomized Controlled Study","Fragmentation Vs Dusting Using TFL With FANS for Renal Stones Less Than 2cm","Inclusion Criteria:\n\n* Age ≥18 years\n* Renal stone(s) confirmed on non-contrast CT KUB\n* Total stone less than 2cm\n* Stone amenable to flexible ureterorenoscopy (FURS)\n* FANS advanced beyond Pelvi-Ureteric Junction (PUJ)\n* Able and willing to provide written informed consent\n* Able to comply with follow-up schedule\n\nExclusion Criteria:\n\n* Active urinary tract infection (positive urine culture) at time of planned surgery\n* Anatomical anomalies precluding safe FURS (e.g., infundibular stenosis, severe calyceal diverticulum inaccessible to flexible scope)\n* Pregnancy or breastfeeding\n* Prior ipsilateral renal surgery within 3 months of enrollment\n* Concurrent ureteral stone(s) requiring simultaneous treatment\n* Renal anomalies: horseshoe kidney, ectopic kidney\n* Sheathless procedure\n* Unable to comply with follow-up or provide consent\n* Participation in another interventional trial within 30 days","ALL","18 Years",{"count":19,"type":20},86,"ESTIMATED","INTERVENTIONAL",[23],"NA","The use of FANS has changed the operative landscape of RIRS by allowing continuous active suction-assisted clearance of ablated stone material in real time. Use of fragmentation technique in FANS requires high-energy to reduce stone burden into small fragments, followed by active suction of residual fine material. Dusting with FANS, on the other hand, converts the entire stone volume into sub-millimetre particulate that is continuously suctioned away during lasing potentially offering a more streamlined workflow with potentially less energy usage, reduced mechanical stress on the ureteroscope working channel, and fewer scope withdrawals. The combination of TFL dusting with FANS-assisted real-time evacuation may produce stone-free outcomes equivalent or superior to fragmentation, while offering these additional operative efficiencies.\n\nWhether dusting using TFL with FANS is non-inferior or indeed superior to fragmentation using TFL with FANS in terms of stone-free rate at one month has not been evaluated in prospective randomised trial yet. This study aims to answer that specific question in patients with renal stone less than 2 cm.",[26,27,28,29],"Thulium Fiber Laser","Fans","Lithotripsy, Laser","Renal Stone",[31,32,33,34],"Dusting","Fragmentation","Thulium fiber laser","FANS","NOT_YET_RECRUITING","2026-06-26",{"date":38,"type":39},"2026-06-30","ACTUAL",{"date":41,"type":20},"2026-08-01",{"date":43,"type":20},"2027-08-07",{"name":45,"class":46},"Bir Hospital","OTHER_GOV",{"id":48,"slug":49,"hasResults":11,"nctId":50,"briefTitle":51,"officialTitle":52,"acronym":53,"eligibilityCriteria":54,"healthyVolunteers":11,"sex":16,"minAge":55,"maxAge":4,"enrollmentInfo":56,"targetDuration":4,"studyType":21,"phases":58,"briefSummary":59,"conditions":60,"keywords":61,"overallStatus":67,"whyStopped":4,"lastUpdateSubmitDate":68,"lastUpdatePostDateStruct":69,"startDateStruct":71,"completionDateStruct":73,"leadSponsor":75,"locationsCount":78},"100624573","supervised-endoscopic-tele-controlled-intelligent-lithotripsy-100624573","NCT07411391","Supervised Endoscopic Tele-controlled Intelligent Lithotripsy","A Feasibility Trial of a Novel Robotic System for Retrograde Intrarenal Surgery","SENTINEL-1","Inclusion criteria\n\n1. Adult patients \\>18 years old\n2. Renal stone(s) less than 1cm 2cm in maximal length\n3. Clinically indicated for RIRS\n4. Willingness to participate as demonstrated by giving informed consent\n\nExclusion criteria\n\n1. Patients with no preoperative CT imaging available\n2. Patients who are not recommended to receive RIRS\n3. Severe concomitant illness that drastically shortens life expectancy or increases risk of therapeutic intervention\n4. Untreated active infection\n5. Un-corrected coagulopathy\n6. Presence of another malignancy or distant metastasis\n7. Emergency surgery\n8. Vulnerable population (e.g. mentally disabled, pregnant)","19 Years",{"count":57,"type":20},15,[23],"This is a phase I feasibility study to investigate the use of a novel intelligent robotic retrograde intrarenal surgery (RIRS) platform. The TaloStone T1000 RIRS system can manipulate the flexible ureteroscope, with remote control of the instruments (laser fibre or basket) and ureteral access sheath movements. Beyond teleoperation, the TaloStone T1000 RIRS system integrates AI perception models and decision-making algorithms to enable the supervised autonomous execution of critical tasks within the RIRS workflow.",[29],[62,63,64,65,66],"Renal stone","Urolithiasis","RIRS","Flexible URS","Supervised autonomy","RECRUITING","2026-04-21",{"date":70,"type":39},"2026-04-24",{"date":72,"type":39},"2026-02-15",{"date":74,"type":20},"2027-03-31",{"name":76,"class":77},"Chinese University of Hong Kong","OTHER",1,{"id":80,"slug":81,"hasResults":11,"nctId":82,"briefTitle":83,"officialTitle":84,"acronym":4,"eligibilityCriteria":85,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":86,"enrollmentInfo":87,"targetDuration":4,"studyType":21,"phases":89,"briefSummary":90,"conditions":91,"keywords":93,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":97,"lastUpdatePostDateStruct":98,"startDateStruct":100,"completionDateStruct":102,"leadSponsor":104,"locationsCount":78},"100632168","retrograde-intrarenal-surgery-versus-extracorporeal-shockwave-lithotripsy-100632168","NCT07510178","Retrograde Intrarenal Surgery Versus Extracorporeal Shockwave Lithotripsy","Role Of Retrograde Intrarenal Surgery Versus Extracorporeal Shockwave Lithotripsy In Lower Calyceal Calculi","Inclusion Criteria\n\n* Those patients will be included with lower calyceal renal stones and size up to 1.5 cm.\n* Patients' ages will be between 18 and 60 years.\n* Both genders will be included.\n\nExclusion Criteria:\n\n* Untreated Urine culture positive will be excluded\n* Patients using anticoagulants and females with pregnancies and those lactating will be excluded.\n* Anatomical abnormalities like horseshoe kidney, duplex system, pelvic kidney, malrotated kidney, calyceal diverticulum, steep infundibulopelvic angle, infundibular stenosis, long infundibular length\u002Fnarrow infundibular width, pelvic ureteric junction obstruction, ureterocele, and ureteral stricture will be excluded.","60 Years",{"count":88,"type":20},66,[23],"The study's aim is to determine which treatment modality, either ESWL or RIRS, is more effective in achieving stone clearance for lower calyceal calculi.\n\nInvestigators hypothesize that retrograde intrarenal surgery is better as compared to extracorporeal shockwave lithotripsy. It will target those patients suffering from kidney stones in lower calyces with sizes up to 1.5 cm in an open-label, randomized controlled trial.",[29,92],"Stone in Calyceal Diverticulum",[94,95,96],"renal stone","lithotripsy","retrograde","2026-04-10",{"date":99,"type":39},"2026-04-15",{"date":101,"type":20},"2026-04-30",{"date":103,"type":20},"2026-10-30",{"name":105,"class":77},"Sindh Institute of Urology and Transplantation",{"id":107,"slug":108,"hasResults":11,"nctId":109,"briefTitle":110,"officialTitle":110,"acronym":4,"eligibilityCriteria":111,"healthyVolunteers":11,"sex":16,"minAge":112,"maxAge":86,"enrollmentInfo":113,"targetDuration":4,"studyType":21,"phases":115,"briefSummary":116,"conditions":117,"keywords":4,"overallStatus":67,"whyStopped":4,"lastUpdateSubmitDate":118,"lastUpdatePostDateStruct":119,"startDateStruct":121,"completionDateStruct":123,"leadSponsor":125,"locationsCount":78},"100598169","erector-spinae-plane-block-for-analgesia-during-eswl-100598169","NCT07067996","Erector Spinae Plane Block for Analgesia During ESWL","Inclusion Criteria:\n\n* Adult Patients undergoing ESWL with 2-3 cm renal stones\n* patients between the ages of 21 and 60,\n* both sexes,\n* BMI ≥18≤30 kg\u002Fm²\n* Able to give informed consent.\n* Patients older than 18 years with American Society of Anesthesiologists Physical Status I or II and\n\nExclusion Criteria:\n\n* Coagulopathy or on anticoagulants\n* Infection at the ESPB injection site\n* BMI ≥30 kg\u002Fm²\n* Patient refusal.\n* patients with advanced respiratory, renal, hepatic, neurological, or psychiatric disease, pregnant or nursing women.\n* patients with a history of allergies to any study drugs","21 Years",{"count":114,"type":20},60,[23],"this study aims to compare between efficacy of erector spinae plane block and conventional multimodal analgesia in Extracorporeal shock wave lithotripsy",[29],"2025-07-06",{"date":120,"type":39},"2025-07-16",{"date":122,"type":39},"2025-06-13",{"date":124,"type":20},"2025-12-15",{"name":126,"class":77},"Sohag University",{"id":128,"slug":129,"hasResults":11,"nctId":130,"briefTitle":131,"officialTitle":132,"acronym":4,"eligibilityCriteria":133,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":134,"targetDuration":4,"studyType":21,"phases":136,"briefSummary":137,"conditions":138,"keywords":4,"overallStatus":67,"whyStopped":4,"lastUpdateSubmitDate":139,"lastUpdatePostDateStruct":140,"startDateStruct":142,"completionDateStruct":144,"leadSponsor":146,"locationsCount":78},"100566879","robotic-flexible-ureteroscopy-versus-standard-flexible-ureteroscopy-for-renal-stones-100566879","NCT06660914","Robotic Flexible Ureteroscopy Versus Standard Flexible Ureteroscopy for Renal Stones","A Randomized Controlled Trial Comparing Robotic Flexible Ureteroscopy With Standard Flexible Ureteroscopy for Treatment of Renal Stones - A Pilot Study","Inclusion Criteria:\n\n* Age ≥ 18 years old with informed consent\n* Being willing and able to provide written informed consent\n\nExclusion Criteria:\n\n* Patients with abnormal urinary tract (e.g. ileal conduit, neobladder, ureteric stricture)\n* American Society of Anesthesiologists (ASA) physical status classification system \\>3\n* Untreated urinary tract infection\n* Renal stones \\> 3cm in diameter",{"count":135,"type":20},30,[23],"This is a prospective randomized clinical trial which aims to compare the clinical outcomes of robotic flexible ureteroscopy and standard flexible ureteroscopy for the treatment of renal stones.",[29],"2025-05-04",{"date":141,"type":39},"2025-05-06",{"date":143,"type":39},"2024-12-01",{"date":145,"type":20},"2026-03-03",{"name":76,"class":77},{"id":148,"slug":149,"hasResults":11,"nctId":150,"briefTitle":151,"officialTitle":152,"acronym":4,"eligibilityCriteria":153,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":154,"targetDuration":4,"studyType":21,"phases":156,"briefSummary":157,"conditions":158,"keywords":4,"overallStatus":67,"whyStopped":4,"lastUpdateSubmitDate":159,"lastUpdatePostDateStruct":160,"startDateStruct":162,"completionDateStruct":164,"leadSponsor":166,"locationsCount":78},"100492830","high-versus-low-power-settings-during-ureteroscopic-laser-lithotripsy-100492830","NCT05697250","High Versus Low Power Settings During Ureteroscopic Laser Lithotripsy","High Versus Low Power Settings During Ureteroscopic Laser Lithotripsy - a Prospective, Randomised Clinical Trial","Inclusion Criteria:\n\n* Patients ≥ 18 years scheduled for URS lithotripsy for renal stones, 8-25 mm, at the day surgery unit at Haukeland University Hospital\n\nExclusion Criteria:\n\n* Concomitant ureteral stone\n* Urinary diversion\n* Active infection\n* Untreated cancer in the upper urinary tract",{"count":155,"type":20},150,[23],"The primary aim of the study is to compare the operative times following ureteroscopic lithotripsy for renal stones with Thulium Fiber Laser using low and high power settings.\n\nSecondary aims are to compare the results of low and high power settings in terms of stone free rates, laser time, laser activation patterns, intraoperative and postoperative complications.\n\nPatients ≥ 18 years with renal stones (8-25 mm) scheduled for ureteroscopic lithotripsy at the Day Surgery Clinic at Haukeland University Hospital in Bergen, Norway, are eligible for inclusion in the study. After written consent and inclusion, patients are randomised to laser lithotripsy using either low power settings (Group 1: 4-6 Watt, short pulse mode) or high power settings (Group 2: 16-18 Watt, short pulse mode). The ureteroscopic procedures are performed in general anaesthesia using a standardised technique. All patients are followed up with a low dose CT scan 3 months post endoscopically to assess stone free status as well as a consultation at the outpatient clinic.\n\nResults and data for the two randomisation groups are compared according to the aims of the study.",[29],"2025-03-03",{"date":161,"type":39},"2025-03-05",{"date":163,"type":39},"2023-01-23",{"date":165,"type":20},"2025-09-30",{"name":167,"class":77},"Haukeland University Hospital",{"id":169,"slug":170,"hasResults":11,"nctId":171,"briefTitle":172,"officialTitle":173,"acronym":4,"eligibilityCriteria":174,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":175,"targetDuration":4,"studyType":177,"phases":4,"briefSummary":178,"conditions":179,"keywords":4,"overallStatus":67,"whyStopped":4,"lastUpdateSubmitDate":180,"lastUpdatePostDateStruct":181,"startDateStruct":183,"completionDateStruct":185,"leadSponsor":187,"locationsCount":188},"100507997","perioperative-parameter-and-treatment-outcomes-of-ecirs-in-asia-100507997","NCT05894668","Perioperative Parameter and Treatment Outcomes of ECIRS in Asia","A Prospective Assessment of the Perioperative Parameter and Treatment Outcomes of Endoscopic Combined Intrarenal Surgery (ECIRS) in Asia","Inclusion Criteria:\n\n* Patients with urinary calculi\n* Undergoing Endoscopic Combined Intrarenal Surgery (ECIRS)\n* Agreed to consent for the study\n\nExclusion Criteria:\n\n* Patients who have ECIRS for other conditions, such as urothelial cancer etc.\n* Patients who intraoperative record was incomplete.\n* Patients only have either PCNL or ureteroscopy done (not both)",{"count":176,"type":20},1000,"OBSERVATIONAL","This is an observational, international, multicenter, cohort study, prospectively collecting clinical data registry on consecutive patients with urinary stone undergoing ECIRS.",[29],"2024-08-21",{"date":182,"type":39},"2024-08-23",{"date":184,"type":39},"2023-08-01",{"date":186,"type":20},"2029-03-31",{"name":76,"class":77},3,{"id":190,"slug":191,"hasResults":11,"nctId":192,"briefTitle":193,"officialTitle":194,"acronym":4,"eligibilityCriteria":195,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":196,"targetDuration":4,"studyType":21,"phases":198,"briefSummary":199,"conditions":200,"keywords":4,"overallStatus":67,"whyStopped":4,"lastUpdateSubmitDate":201,"lastUpdatePostDateStruct":202,"startDateStruct":204,"completionDateStruct":206,"leadSponsor":207,"locationsCount":78},"100503294","effect-of-preoperative-silodosin-on-feasibility-of-ureteral-access-sheath-insertion-100503294","NCT05833386","Effect of Preoperative Silodosin on Feasibility of Ureteral Access Sheath Insertion","Effect of Preoperative Silodosin on Feasibility of Ureteral Access Sheath Insertion for Flexible Ureteroscope in Treating Renal Stones; A Prospective, Multicentre, Randomized Trial","Inclusion Criteria:\n\n* All patients with renal stones who will undergo flexible ureteroscopy and planned for using ureteral access sheath\n\nExclusion Criteria:\n\n* Paediatric age group (less than 18 year)",{"count":197,"type":20},2000,[23],"The ureteral access sheath (UAS) is an ancillary device widely used by urologists to facilitate fast, repeatable, and safe access to ureters and collecting systems; improve visibility; reduce the risk of infection by reducing intrarenal pressure; and protect ureters and scopes when extracting multiple stones during surgery.\n\nInsertion of ureteric access sheath may be difficult due to tight ureter, so sometimes preoperative stenting might be needed. Silodosin is an α1A adrenoceptor with high affinity and selectivity for the ureteric muscle, which may reduce ureteral spasm.\n\nOral a1-blockers can reduce intraureteral pressure, and may reduce maximal ureteral access sheath insertion force.¹ Preoperative silodosin protects against significant ureteral injury related to UAS insertion during fURS and decreases postoperative pain level. Silodosin premedication might be an effective and safe technique to replace prestenting.²",[29],"2023-08-07",{"date":203,"type":39},"2023-08-08",{"date":205,"type":39},"2022-10-01",{"date":41,"type":20},{"name":208,"class":77},"Al-Azhar University"]