[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"reproducibility-of-results\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:reproducibility-of-results":29},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,45],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":20,"targetDuration":23,"studyType":24,"phases":4,"briefSummary":25,"conditions":26,"keywords":4,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":33,"lastUpdatePostDateStruct":34,"startDateStruct":37,"completionDateStruct":39,"leadSponsor":41,"locationsCount":44},"100562580","somatic-dysfunction-in-patients-with-acute-cerebrovascular-disease-100562580",false,"NCT06605014","Somatic Dysfunction in Patients With Acute Cerebrovascular Disease","Characterization of Somatic Dysfunction in Patients With Acute Cerebrovascular Disease","SOMADC-AC","Inclusion Criteria:\n\n* adults ≥18 years\n\nAdmission diagnosis:\n\n* ischemic stroke OR\n* transient ischemic attack (TIA). A prior history of TIA but without stroke may be enrolled.\n* Neurologic stability or lack of significant deterioration (i.e. ∆ NIHSS\\\u003C4) for at least 24 hours (defined by clinical documentation and\u002For communication with provider team(s)) in stroke subjects\n* Able to sit upright, lie supine, and when able lateral recumbent left\u002Fright positions with assist independently or with minimal person assist\n* Anticipated length of stay greater \\> or = 2 days for ischemic stroke. TIA patients average length of stay is \\\u003C 2 days, and can be enrolled in the study.\n\nExclusion Criteria:\n\n* Acute skeletal fracture or known dislocation; history of pathologic (osteoporotic or neoplastic) skeletal fracture of thoracic cage, hip\u002Fpelvis\u002Fsacrum, or vertebral column\n* Prior history of ICH, ischemic stroke, confirmed by imaging and\u002For clinical evaluation. Patients with imaging showing \"chronic stroke\" who have never received a diagnosis of stroke and\u002For have not been previously symptomatic may still be enrolled, based on the Investigator's clinical judgement.\n* Spinal column support brace (e.g. cervical collar)\n* Anticipated neurosurgical intervention during hospitalization: decompressive hemicraniectomy, hematoma evacuation (defined by clinical documentation and\u002For communication with provider team(s))\n* Current endotracheal intubation (\\*note: extubated patients can be evaluated for eligibility)\n* History of spinal cord injury with residual neuromuscular or sensory disability\n* History of recent trauma within the past 30 days\n* Known ligament, musculotendinous, or bone lesion\n* Clinical condition that would interfere with execution of movement or palpatory diagnostic testing, e.g. chronic pain\n* History of spinal surgery",true,"ALL","18 Years",{"count":21,"type":22},120,"ESTIMATED","90 Days","OBSERVATIONAL","The goals of this observational study are to test the reliability of a new, standardized physical examination method to identify motion problems within joints or groups of joints among adult asymptomatic volunteers and in patients hospitalized with stroke or stroke-like episodes (e.g., transient ischemic attack, TIA). The main questions this investigation aims to answer are:\n\n* Can different, independent providers reliability quantify motion pattern problems using a systematic approach called, The Functional Pathology of the Musculoskeletal System (FPMSS) model?\n* Are there differences in joint(s) motion patterns among asymptomatic volunteers, patients with TIA (people with brain disease without new neurologic disability), and recent ischemic stroke (patients with new stroke-related-disability, e.g., paralysis)?\n* Is there an association between joint(s) motion impairment severity and stroke survivor outcomes?\n\nParticipants (asymptomatic and those with stroke) will undergo a set of repeated paired, musculoskeletal physical exams by independent providers blinded to each other's assessments and patient information. Researchers will compare the severity, location, and quantity of joint(s) motion impairment between these three groups with the physical examination methodology (FPMSS). Clinical information (e.g., test results, diagnoses, brain imaging, medical history) will be collected from patients admitted for TIA and stroke. Enrolled participants with recent stroke will complete a survey three months after hospitalization to determine their self-perceived quality-of-life.",[27,28,29,30,31],"Stroke, Acute","TIA","Reproducibility of Results","Osteopathic Manipulation","Health-Related Quality-of-Life","RECRUITING","2025-09-24",{"date":35,"type":36},"2025-09-26","ACTUAL",{"date":38,"type":36},"2023-09-01",{"date":40,"type":22},"2026-08-31",{"name":42,"class":43},"University of California, Davis","OTHER",1,{"id":46,"slug":47,"hasResults":11,"nctId":48,"briefTitle":49,"officialTitle":49,"acronym":50,"eligibilityCriteria":51,"healthyVolunteers":11,"sex":18,"minAge":52,"maxAge":53,"enrollmentInfo":54,"targetDuration":4,"studyType":24,"phases":4,"briefSummary":56,"conditions":57,"keywords":68,"overallStatus":78,"whyStopped":4,"lastUpdateSubmitDate":79,"lastUpdatePostDateStruct":80,"startDateStruct":82,"completionDateStruct":84,"leadSponsor":86,"locationsCount":5},"100601977","heterogeneity-index-in-neonatologist-performed-lung-ultrasound-in-neonates-receiving-respiratory-support---a-pilot-study-100601977","NCT07117513","Heterogeneity Index in Neonatologist-performed Lung Ultrasound in Neonates Receiving Respiratory Support - a Pilot Study","NPLUS HI","Inclusion Criteria:\n\n* Preterm neonates born between 28+0 and 36+6 weeks of gestation and term-born neonates (\\> 37+0 weeks of gestation) admitted to the NICU\n* Presence of respiratory distress requiring respiratory support (invasive and non-invasive) at the timepoint of NPLUS 1.\n* Written informed consent obtained from the parents prior to the measurement.\n\nExclusion Criteria:\n\n* cardiopulmonary malformations\n* pleural effusion\n* pneumothorax","1 Hour","7 Days",{"count":55,"type":22},40,"Lung ultrasound is an increasingly valuable diagnostic tool in neonatal intensive care due to its safety and accessability.\n\nThis pilot study investigates whether a quantitative approach - the heterogeneity index, previously only used in fetal lung assessment - can enhance the diagnostic accuracy of neonatologist-performed lung ultrasound (NPLUS). The index will be calculated from raw ultrasound images of preterm and term neonates and compared with conventional lung ultrasound scores to evaluate its clinical relevance.",[58,59,60,61,62,63,64,65,29,66,67],"Intensive Care Units, Neonatal","Infant, Newborn","Infant, Premature","Point-of-Care Systems","Ultrasonography","Lung Ultrasound","Lung Ultrasound Score","Image Interpretation, Computer Assisted","Respiratory Distress Neonatal","Respiratory Support",[69,63,64,70,71,72,73,74,75,76,77],"Neonatologist-Performed Lung Ultrasound","Quantitative Lung Ultrasound","Neonatal Intensive Care Unit","Observer Variability in Imaging","Ultrasound Artifact Interpretation","Respiratory Distress Syndrome in Neonates","respiratory support","preterm neonate","newborn","NOT_YET_RECRUITING","2025-08-05",{"date":81,"type":36},"2025-08-12",{"date":83,"type":22},"2025-08-15",{"date":85,"type":22},"2026-08-01",{"name":87,"class":43},"Medical University of Graz"]