[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"resistance-exercise\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:resistance-exercise":29},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,8,0,[8,45,72,94,124,154,197,226],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":4,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":33,"lastUpdatePostDateStruct":34,"startDateStruct":37,"completionDateStruct":39,"leadSponsor":41,"locationsCount":44},"100599690","optimizing-gait-symmetry-after-stroke-using-mechanical-constraints-and-sensory-feedback-100599690",false,"NCT07087769","Optimizing Gait Symmetry After Stroke Using Mechanical Constraints and Sensory Feedback","Optimizing Post-Stroke Gait Symmetry: Integrating Mechanical Constraints and Sensory Feedback to Enhance Paretic Leg Propulsion","Inclusion Criteria:\n\nAged 20 years or older\n\nFor stroke group: clinical diagnosis of stroke at least 1 month prior to participation\n\nAbility to walk at least 10 meters with or without assistive devices\n\nFor healthy group: able to walk independently without assistive devices\n\nExclusion Criteria:\n\nLife expectancy less than one year\n\nComatose or unable to follow three-step commands\n\nAmputation of any lower limb\n\nPoorly controlled diabetes (e.g., foot ulceration)\n\nBlindness\n\nProgressive neurological disease\n\nMedically unstable condition\n\nSignificant musculoskeletal impairments affecting gait\n\nCongestive heart failure or unstable angina\n\nPeripheral vascular disease\n\nSevere neuropsychiatric conditions (e.g., dementia, cognitive deficits, severe depression)",true,"ALL","20 Years",{"count":20,"type":21},30,"ESTIMATED","INTERVENTIONAL",[24],"NA","This single-session study aims to evaluate a novel gait training protocol that integrates mechanical constraints and sensory feedback to enhance paretic leg propulsion in individuals post-stroke. The study will include 15 individuals who have experienced a stroke and 15 healthy adults, each aged 20 years or older. Participants will walk on both tied-belt and split-belt treadmills under various training conditions, including backward-directed resistance (applied at the pelvis, ankle, or both) and real-time sensory feedback (visual, auditory, or combined). These interventions will be applied individually and in combination to identify the most effective environment for promoting symmetrical gait patterns. Each session will last approximately two hours. The equipment used is non-invasive, and the risk to participants is minimal.",[27,28,29,30,31],"Stroke","Split-belt Treadmill","Resistance Exercise","Feedback","Gait Training","RECRUITING","2026-03-31",{"date":35,"type":36},"2026-04-01","ACTUAL",{"date":38,"type":36},"2025-07-25",{"date":40,"type":21},"2026-12-01",{"name":42,"class":43},"The University of Texas Medical Branch, Galveston","OTHER",1,{"id":46,"slug":47,"hasResults":11,"nctId":48,"briefTitle":49,"officialTitle":50,"acronym":4,"eligibilityCriteria":51,"healthyVolunteers":16,"sex":17,"minAge":52,"maxAge":53,"enrollmentInfo":54,"targetDuration":4,"studyType":22,"phases":56,"briefSummary":57,"conditions":58,"keywords":4,"overallStatus":62,"whyStopped":4,"lastUpdateSubmitDate":63,"lastUpdatePostDateStruct":64,"startDateStruct":66,"completionDateStruct":68,"leadSponsor":70,"locationsCount":44},"100631043","comparison-of-the-effects-of-free-weight-and-machine-based-exercises-on-muscular-parameters-100631043","NCT07495540","Comparison of the Effects of Free Weight and Machine-Based Exercises on Muscular Parameters","Comparison of Free Weight and Machine-Based Exercise Effects on Muscular Parameters","Inclusion Criteria:\n\n* Being an individual between the ages of 18-30 years\n* Being physically inactive according to the International Physical Activity Questionnaire short form (\\\u003C600 MET-min\u002Fweek)\n* Residing in Istanbul\n* Voluntary participation in the study.\n\nExclusion Criteria:\n\n* Having a neurological or cardiopulmonary system problem that prevents exercise.\n* Having mental dysfunction.\n* Having an acute musculoskeletal injury which limits exercise participant\n* Being pregnant.\n* Having answered \"YES\" to any question on the Exercise Readiness Questionnaire.","18 Years","30 Years",{"count":55,"type":21},26,[24],"The aim of our study is to compare and investigate the effects of resistance exercises performed with free weights and those performed using machine systems on muscular parameters and neuromuscular control.",[29,59,60,61],"Neuromuscular Adaptations","Muscle","Adult","NOT_YET_RECRUITING","2026-03-21",{"date":65,"type":36},"2026-03-27",{"date":67,"type":21},"2026-03-23",{"date":69,"type":21},"2026-06-01",{"name":71,"class":43},"Biruni University",{"id":73,"slug":74,"hasResults":11,"nctId":75,"briefTitle":76,"officialTitle":76,"acronym":4,"eligibilityCriteria":77,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":53,"enrollmentInfo":78,"targetDuration":4,"studyType":22,"phases":79,"briefSummary":80,"conditions":81,"keywords":4,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":85,"lastUpdatePostDateStruct":86,"startDateStruct":88,"completionDateStruct":90,"leadSponsor":92,"locationsCount":44},"100627083","effect-of-resistance-exercise-on-energy-balance-and-appetite-regulation-in-males-and-females-100627083","NCT07444021","Effect of Resistance Exercise on Energy Balance and Appetite Regulation in Males and Females","Inclusion Criteria:\n\n* Healthy males and females aged 20-30 years\n* Females with a regular menstrual cycle\n* Stable body weight, defined as no significant change in body weight during the past 6 months\n* Willingness to participate and provide written informed consent\n\nExclusion Criteria:\n\n* Obesity, defined as:\n* Body mass index (BMI) \\> 30 kg\u002Fm²\n* Body fat percentage \\> 25% in males\n* Body fat percentage \\> 30% in females\n* Hypertension, defined as resting blood pressure \\> 140\u002F90 mmHg\n* History of cardiovascular disease\n* History of cancer\n* History of liver disease\n* History of kidney disease\n* Presence of any medical condition that may interfere with study outcomes",{"count":20,"type":21},[24],"There is growing evidence that males and females may exhibit different acute responses and long-term adaptations to exercise training. Accordingly, contemporary exercise physiology research increasingly recognizes sex as an important biological variable that may influence appetite regulation and energy balance.\n\nThis year's project aims to investigate: (1) appetite regulation and energy balance following acute resistance exercise, and (2) potential sex-based differences in appetite regulation and energy balance in response to resistance exercise.\n\nUnderstanding both the overall effects of resistance exercise and sex-related variability in these responses is important for improving the physiological interpretation of exercise-induced changes in appetite and energy balance. Such knowledge may help to reduce heterogeneity in exercise research findings and support the development of more precise, evidence-based exercise prescriptions that are applicable to both males and females.",[82,83,84,29],"Energy Balance","Energy Expenditure","Males and Females","2026-02-25",{"date":87,"type":36},"2026-03-02",{"date":89,"type":36},"2025-12-01",{"date":91,"type":21},"2026-12-30",{"name":93,"class":43},"National Taiwan Normal University",{"id":95,"slug":96,"hasResults":11,"nctId":97,"briefTitle":98,"officialTitle":98,"acronym":4,"eligibilityCriteria":99,"healthyVolunteers":16,"sex":17,"minAge":52,"maxAge":100,"enrollmentInfo":101,"targetDuration":4,"studyType":22,"phases":102,"briefSummary":103,"conditions":104,"keywords":109,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":115,"lastUpdatePostDateStruct":116,"startDateStruct":118,"completionDateStruct":120,"leadSponsor":122,"locationsCount":44},"100619446","impact-of-haskap-berries-on-recovery-from-high-intensity-resistance-training-100619446","NCT07344727","Impact of Haskap Berries on Recovery From High Intensity Resistance Training","Inclusion Criteria:\n\n* 2+ years of barbell squat experience\n* Currently squatting at least once a week\n\nExclusion Criteria:\n\n* BMI \\\u003C18 or \\> 40 kg\u002Fm\\^2\n* potential allergy to Haskap or placebo ingredients\n* anti-inflammatory, weight loss, anabolic steroids, testosterone, or other drugs that may interfere with the measures of the study or any other medications that may interfere with study measures\n* pregnant or lactating woman\n* diagnosis with type 1 or type 2 diabetes, hypo-\u002Fhyperthyroidism or any other condition that may interfere with study measures\n* smoke cigarettes\n* lower extremity injury within the last year\n* currently following a special diet including vegan, vegetarian, low carbohydrate, or ketogenic.\n* currently consuming any of the following products: tart cherry juice, pomegranate juice, or 1 or more cups of acai or other berries per day.","35 Years",{"count":20,"type":21},[24],"The purpose of this clinical trial is to determine how certain food items affect oxidative stress, inflammation, and performance recovery from exercise induced muscle damage in a resistance trained population. The main questions The investigators aim to answer are the following:\n\n* Do Haskaps speed the recovery of oxidative stress and inflammation markers after an intense lower body workout in resistance trained adults?\n* Do Haskaps speed the recovery of performance measures after an intense lower body workout in resistance trained adults?\n* The data collected in this investigation may also be used to ask additional questions not yet identified. For example, the investigators may use the stored samples to evaluate how the blood metabolites of participants differ before and after intense exercise. These additional questions are called secondary analyses. Please note that no genetic analysis will be conducted and racial and ethnic differences among participants will not be used in any secondary analyses.\n\nResearches will compare Haskap juice to a color, flavor and carbohydrate matched placebo to see if Haskaps speed recovery in inflammation, oxidative stress and performance.\n\n* Participants will be asked to drink either Haskap juice or placebo and follow a low polyphenolic diet\n* Participants will perform an intense resistance workout\n* Participants will have their blood drawn before and after the workout\n* Performance will be analyzed at 24, 48 and 72 hours after the workout",[105,106,29,107,108],"Inflammation","Oxidative Stress","Recovery","Exercise Performance Recovery",[110,111,112,113,114],"exercise performance","resistance exercise","recovery","oxidative stress","inflammation","2026-01-19",{"date":117,"type":36},"2026-01-21",{"date":119,"type":36},"2025-10-21",{"date":121,"type":21},"2026-05",{"name":123,"class":43},"Montana State University",{"id":125,"slug":126,"hasResults":11,"nctId":127,"briefTitle":128,"officialTitle":129,"acronym":4,"eligibilityCriteria":130,"healthyVolunteers":11,"sex":131,"minAge":52,"maxAge":132,"enrollmentInfo":133,"targetDuration":4,"studyType":22,"phases":135,"briefSummary":136,"conditions":137,"keywords":141,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":145,"lastUpdatePostDateStruct":146,"startDateStruct":148,"completionDateStruct":150,"leadSponsor":152,"locationsCount":44},"100598384","combined-upper-extremity-resistance-and-aerobic-exercise-training-in-patients-with-breast-cancer-100598384","NCT07070791","Combined Upper Extremity Resistance and Aerobic Exercise Training in Patients With Breast Cancer","Investigation of the Effect of Combined Upper Extremity Resistance and Aerobic Exercise Training on Arm Exercise Capacity, Peripheral Muscle Strength and Arm Functionality in Patients With Breast Cancer","Inclusion Criteria:\n\n* To be between 18-80 years old,\n* Volunteering to participate in the research,\n* At least 15 months after breast cancer surgery,\n* No problems in reading and\u002For understanding the scales and being able to co-operate with the tests.\n* Physically inactive (60 minutes of structured exercise per week \\\u003C).\n\nExclusion Criteria:\n\n* Presence of active infection,\n* Presence of bilateral breast cancer,\n* History of surgical, neurological or orthopaedic problems that may affect upper extremity functionality other than breast cancer surgery,\n* Having a neurological disease or other clinical diagnosis that may affect cognitive status,\n* Musculoskeletal and neurological disease that may affect exercise performance, symptomatic heart disease, previous lung surgery and malignant disease.\n* Presence of unstable hypertension or diabetes mellitus.","FEMALE","80 Years",{"count":134,"type":21},40,[24],"According to updated data from the International Agency for Research on Cancer (IARC) for 2022, breast cancer in women is responsible for one in four cancer cases and one in six cancer deaths worldwide and is the second leading cause of global cancer incidence, accounting for 11.6% of all cancer cases, and the fourth leading cause of cancer deaths worldwide, accounting for 6.9% of all cancer deaths. During or after breast cancer treatments, there is exposure to a variety of direct (local\u002Fregional treatment, systemic treatment and supportive care) and indirect factors (modifiable and non-modifiable risk factors) that may have adverse effects on treatment-related haematological, cardiovascular, pulmonary and musculoskeletal components. Upper limb dysfunction and lymphoedema have been reported to be two of the most common side effects affecting the quality of life of breast cancer patients after breast cancer treatments. The elastic resistance band, which is widely used in strength training, has the advantage of being applied to various classes because it provides resistance angles in various postures and has a low risk of injury. However, few studies have been conducted on elastic resistance band application in patients with breast cancer. At the same time, evidence on the effectiveness of upper extremity aerobic exercise training in patients with breast cancer is limited. Therefore, this study aimed to investigate the effects of upper extremity aerobic exercise training combined with progressive resistance training and upper extremity aerobic exercise training alone on upper extremity exercise capacity, upper extremity functionality, sarcopenia, frailty, quality of life and lymphedema in patients with breast cancer.",[138,139,29,140],"Breast Cancer","Upper Extremity","Aerobic Exercise",[142,139,143,144],"breast cancer","resistance exercise training","Aerobic exercise training","2025-12-25",{"date":147,"type":36},"2025-12-29",{"date":149,"type":36},"2025-07-08",{"date":151,"type":21},"2026-07-01",{"name":153,"class":43},"Hacettepe University",{"id":155,"slug":156,"hasResults":11,"nctId":157,"briefTitle":158,"officialTitle":159,"acronym":160,"eligibilityCriteria":161,"healthyVolunteers":16,"sex":17,"minAge":52,"maxAge":100,"enrollmentInfo":162,"targetDuration":4,"studyType":22,"phases":164,"briefSummary":165,"conditions":166,"keywords":173,"overallStatus":62,"whyStopped":4,"lastUpdateSubmitDate":189,"lastUpdatePostDateStruct":190,"startDateStruct":192,"completionDateStruct":194,"leadSponsor":195,"locationsCount":44},"100610994","resistance-exercise-and-sleep-quality-by-chronotype-100610994","NCT07234812","Resistance Exercise and Sleep Quality by Chronotype","The Effects of Tailored Resistance Exercise on Sleep Quality in Relation to Chronotype","TRE-SLEEP","Inclusion Criteria:\n\n* Age between 18 and 35 years\n* Generally healthy, with mild to moderate sleep disturbance as categorized by the Pittsburgh Sleep Quality Index (PSQI)\n* Body Mass Index (BMI) \\\u003C 35 kg\u002Fm²\n* No physical or organic limitations or diseases that would prevent participation in physical activity\n* Non-smoker and non-alcoholic\n* Caffeine consumption ≤ 2 cups per day (including coffee and energy drinks)\n* Have not participated in more than 60 minutes\u002Fweek of usual moderate-to-vigorous physical activity in the past 6 months, categorized as \"moderate\" on the International Physical Activity Questionnaire-Short Form (IPAQ-SF)\n* No clinically diagnosed sleep apnea or other medical\u002Fpsychiatric disorders responsible for sleep complaints\n* Regular sleep schedule (no night shifts or transmeridian travel) in the 30 days prior to study enrollment\n* Able to speak and write English\n\nExclusion Criteria:\n\n* Current use of medications or psychotherapeutic drugs for insomnia or other psychiatric disorders\n* Use of melatonin or other sleep aids in the past month\n* Currently performing any aerobic or mind-body exercise classes (e.g., yoga, Pilates)\n* Habitual daytime napping\n* History of epilepsy or other convulsive disorders\n* Pregnant individuals\n* Habitual or recent use (within the past 30 days) of illegal drugs, psychotropic drugs, hypnotics, stimulants, or analgesics",{"count":163,"type":21},64,[24],"This study examines whether doing moderate resistance exercises in the morning can improve sleep quality and well-being in young adults. Participants with different daily activity patterns (morning or evening types) will take part in an 8-week online exercise program. The study will compare how exercise affects sleep, mood, and daily rhythm across these groups.",[167,29,168,169,170,171,172],"Physical Therapy","Sleep Disturbances","Sleep Quality","Chronotype","Circadian Rhythm","Health Behavior \u002F Well-Being",[174,175,170,176,177,178,179,180,181,167,182,183,184,185,186,187,188],"sleep disturbance","Sleep quality","Morningness-eveningness","Circadian rhythm","Resistance exercise","Home-based exercise","Sleep and exercise","Physical activity and sleep","Exercise","Telerehabilitation","Munich Chronotype Questionnaire (MCTQ)","Pittsburgh Sleep Quality Index (PSQI)","Mood (BRUMS, DASS-21)","Randomized controlled trial","Physical therapy and rehabilitation","2025-11-18",{"date":191,"type":36},"2025-11-20",{"date":193,"type":21},"2025-12",{"date":121,"type":21},{"name":196,"class":43},"Medipol University",{"id":198,"slug":199,"hasResults":11,"nctId":200,"briefTitle":201,"officialTitle":202,"acronym":4,"eligibilityCriteria":203,"healthyVolunteers":11,"sex":17,"minAge":204,"maxAge":4,"enrollmentInfo":205,"targetDuration":4,"studyType":22,"phases":207,"briefSummary":208,"conditions":209,"keywords":212,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":217,"lastUpdatePostDateStruct":218,"startDateStruct":220,"completionDateStruct":222,"leadSponsor":224,"locationsCount":44},"100531849","effects-of-elastic-band-resistance-exercise-on-muscle-strength-and-depression-in-hospitalized-elderly-100531849","NCT06205147","Effects of Elastic Band Resistance Exercise on Muscle Strength and Depression in Hospitalized Elderly.","Effects of Elastic Band Resistance Exercise on Muscle Strength and Depression in Hospitalized Elderly Patients.","Inclusion Criteria:\n\n1. Age of 65 years or older.\n2. Anticipated hospital stay exceeding 7 days.\n3. Able to follow instructions.\n4. Four-limb muscle strength of at least three points, and grip strength measurements with a minimum of 26 kilograms for males and 18 kilograms for females.\n\nExclusion Criteria:\n\n1. This includes individuals with cardiovascular diseases such as acute myocardial infarction, unstable angina, poorly controlled arrhythmias, complete atrioventricular block, acute heart failure, acute myocarditis, acute pericarditis, and other cardiac conditions.\n2. Poorly controlled hypertension, with systolic blood pressure less than 90 mmHg or greater than 200 mmHg under medication.\n3. Individuals hospitalized due to acute neurological injuries or conditions, such as epilepsy, stroke, or Parkinson's disease.\n4. Diagnosed with cognitive impairment or Alzheimer's disease.\n5. Those who require long-term ventilator support and are unable to participate in the program.\n6. Individuals with impaired consciousness who cannot cooperate.\n7. A Glasgow Coma Scale score of less than 12, or inability to correctly answer questions about person, time, place, or follow instructions.","65 Years",{"count":206,"type":21},62,[24],"With improved a five-day intensive, low-resistance elastic band exercise program to evaluate its effectiveness in improving total muscle mass, upper and lower extremity muscle strength, self-perceived fear of falling, and depression among hospitalized elderly individuals. This study is a random control trial. Data collection includes elderly patient's total muscle mass, upper and lower extremity muscle strength, self-perceived fear of falling, and depression among hospitalized. The total muscle mass and upper and lower extremity muscle strength will be calculated in kilograms.",[29,210,211],"Muscle Weakness","Functional Decline",[111,213,214,215,216],"hospitalized elderly","muscle strength","depression","Functional decline","2025-07-21",{"date":219,"type":36},"2025-07-24",{"date":221,"type":36},"2025-03-05",{"date":223,"type":21},"2025-12-31",{"name":225,"class":43},"National Taiwan University",{"id":227,"slug":228,"hasResults":11,"nctId":229,"briefTitle":230,"officialTitle":231,"acronym":4,"eligibilityCriteria":232,"healthyVolunteers":11,"sex":131,"minAge":52,"maxAge":233,"enrollmentInfo":234,"targetDuration":4,"studyType":235,"phases":4,"briefSummary":236,"conditions":237,"keywords":4,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":240,"lastUpdatePostDateStruct":241,"startDateStruct":243,"completionDateStruct":245,"leadSponsor":247,"locationsCount":44},"100591822","the-effect-of-the-menstrual-cycle-on-immune-cell-activity-and-recovery-after-resistance-exercise-100591822","NCT06985420","The Effect of the Menstrual Cycle on Immune Cell Activity and Recovery After Resistance Exercise","The Impact of the Menstrual Cycle on Innate Immune Cell Activation, Recruitment, and Adhesion Dynamics During Recovery From Damaging Resistance Exercise: Role of Neutrophils and Systemic Chemokines.","Inclusion Criteria:\n\n* Women between the ages of 18 and 40.\n* Must weigh at least 110 pounds.\n* Healthy as determined by medical history, physical activity readiness, and menstrual cycle questionnaires.\n* Actively resistance training for at least 6 months (minimum of 3 resistance training sessions per week, with at least one lower body session).\n* Pre-menopausal and have a regular menstrual cycle (eumenorrheic), with a clear start of menses (early follicular phase).\n* Not currently pregnant or planning to become pregnant during the study.\n* Have not used hormonal birth control or intrauterine devices in the past 3 months (or three full menstrual cycles).\n* Able to recall approximate start dates of their last 6 menstrual cycles.\n* Willing to follow study instructions, including avoiding exercise, alcohol, and caffeine before testing visits.\n* Free from previous or current lower body injuries that could limit performance.\n* Not regularly taking any medications that could interfere with the study.\n* Determined to have a high likelihood of successful blood draws by a certified phlebotomist.\n\nExclusion Criteria:\n\n* Do not give consent to participate.\n* Have been determined unfit to participate based on medical or activity history (using health questionnaires).\n* Currently take prescription or over-the-counter medication that could affect the study results.\n* Have a chronic illness requiring medical care.\n* Not currently resistance-trained (don't meet the exercise requirement).\n* Pregnant or planning to become pregnant during the study.\n* Do not have regular periods or have been diagnosed as amenorrhoeic (absence of menstruation).\n* Currently taking any performance-enhancing drugs.\n* Currently using hormonal birth control or intrauterine devices (IUDs), or have used them in the past three months (or three full menstrual cycles).\n* Determined unlikely to have a successful blood draw by a trained phlebotomist.\n* Weigh less than 110 pounds.","40 Years",{"count":134,"type":21},"OBSERVATIONAL","The goal of this observational study is to learn how the menstrual cycle affects immune cell activation, recruitment, and recovery responses after resistance exercise in healthy, resistance-trained women aged 18-40. The main questions it aims to answer are:\n\nDoes the menstrual cycle influence neutrophil recruitment and adhesion after resistance exercise? Does the menstrual cycle affect markers of muscle damage and functional recovery? Researchers will compare three menstrual phases (early follicular, late follicular, and mid-luteal) to see if immune responses and recovery outcomes differ across these phases.\n\nParticipants will:\n\nComplete resistance exercise protocols across three different menstrual cycle phases.\n\nProvide blood samples to assess immune cell activation and muscle damage markers.\n\nTrack sleep, mood, and recovery with questionnaires and wear an accelerometer.",[238,239,29],"Healthy Women","Menstruation","2025-05-14",{"date":242,"type":36},"2025-05-22",{"date":244,"type":36},"2024-08-16",{"date":246,"type":21},"2025-05",{"name":248,"class":43},"University of Central Florida"]