[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"respiratory-acidosis\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:respiratory-acidosis":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,42],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":4,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":30,"lastUpdatePostDateStruct":31,"startDateStruct":34,"completionDateStruct":36,"leadSponsor":38,"locationsCount":41},"100579630","ventilo-prospective-study-100579630",false,"NCT06826794","VentilO Prospective Study","Frequency of Respiratory Acidosis in the Intensive Care Unit After Postoperative Cardiac Surgery. Impact of Using VentilO Application","VentilO","Inclusion Criteria:\n\n* Adults (\\> 18 years old)\n* Intubated patients admitted to intensive care immediately post-operatively after cardiac surgery (all cardiac surgery combined)\n* Ventilation in controlled mode (Assist Control or SIMV)\n\nExclusion Criteria:\n\n* Absence of anthropometric data (height and weight) of patients available in the patient file\n* Respiratory cycles mainly spontaneous on arrival\n* Patient extubated on arrival in intensive care","ALL","18 Years",{"count":20,"type":21},76,"ESTIMATED","INTERVENTIONAL",[24],"NA","This is a randomized, open-label study comparing intial settings made by clinicians with settings recommandation made by the VentilO application immediately after intensive care unit admission.The study will allow direct comparison of the frequency of acidosis when patients are ventilated using the parameters of the VentilO application versus parameters chosen by the clinician. The variables determined by the clinician or VentilO will be respiratory rate, tidal volume and resulting minute ventilation.",[27,28],"Mechanical Ventilation Complication","Respiratory Acidosis","RECRUITING","2025-08-27",{"date":32,"type":33},"2025-09-04","ACTUAL",{"date":35,"type":33},"2025-04-24",{"date":37,"type":21},"2027-06",{"name":39,"class":40},"Laval University","OTHER",1,{"id":43,"slug":44,"hasResults":11,"nctId":45,"briefTitle":46,"officialTitle":47,"acronym":48,"eligibilityCriteria":49,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":50,"targetDuration":4,"studyType":22,"phases":52,"briefSummary":53,"conditions":54,"keywords":56,"overallStatus":60,"whyStopped":4,"lastUpdateSubmitDate":61,"lastUpdatePostDateStruct":62,"startDateStruct":64,"completionDateStruct":66,"leadSponsor":67,"locationsCount":41},"100599229","evaluation-of-the-effects-on-carbon-dioxide-paco2-of-a-new-oronasal-mask-in-patients-with-severe-copd-exacerbation-requiring-non-invasive-mechanical-ventilation-100599229","NCT07081776","Evaluation of the Effects on Carbon Dioxide (paCO2) of a New Oronasal Mask in Patients With Severe COPD Exacerbation Requiring Non-Invasive Mechanical Ventilation","Evaluation of the Effects on Carbon Dioxide (paCO2) of a New Oronasal Mask in Patients With Severe Exacerbation of COPD Requiring Non-Invasive Mechanical Ventilation: A Single-Center, Exploratory, Randomized Cross-Over Study","OPTIMUS-MASK","Inclusion Criteria:\n\n* Age ≥ 18 years\n* Informed consent obtained\n* Patients with COPD and acute hypoxemic-hypercapnic respiratory failure (pH \\\u003C 7.35, PaO₂ \\\u003C 60 mmHg, PaCO₂ \\> 45 mmHg) requiring non-invasive mechanical ventilation.\n\nExclusion Criteria:\n\n* BMI ≥ 30 kg\u002Fm²\n* Obstructive sleep apnea syndrome\n* Neuromuscular diseases or chest wall pathologies\n* Need for intubation and invasive mechanical ventilation during exacerbation\n* Use of home non-invasive mechanical ventilation or CPAP\n* Contraindications for NIV\n* Cognitive disorders that may interfere with adherence to treatments\n* Patients with active and unstable coronary artery disease\n* Previous esophageal surgery, known esophageal stenosis, or any other condition that could put the patient at risk during the placement of the respiratory mechanics probe",{"count":51,"type":21},21,[24],"This single-center, crossover study aims to investigate the effects of the new OptiNIV oronasal mask used during NIV in COPD patients with respiratory acidosis following an exacerbation. The goal is to evaluate whether the clinical benefits, in terms of reducing PaCO2 levels, are greater with the new mask compared to a traditional one (Visairo Mask).",[55,28],"COPD",[55,57,58,59],"NIV","Oronasal Mask","PaCO2","NOT_YET_RECRUITING","2025-07-21",{"date":63,"type":33},"2025-07-23",{"date":65,"type":21},"2025-08",{"date":37,"type":21},{"name":68,"class":40},"IRCCS Azienda Ospedaliero-Universitaria di Bologna"]