[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"respiratory-complication\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:respiratory-complication":25},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,7,0,[8,40,68,88,112,135,167],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":15,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":23,"conditions":24,"keywords":4,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":28,"lastUpdatePostDateStruct":29,"startDateStruct":32,"completionDateStruct":34,"leadSponsor":36,"locationsCount":39},"100571600","characterization-of-fetal-lung-with-quantitative-ultrasound-100571600",false,"NCT06722365","Characterization of Fetal Lung With Quantitative Ultrasound","Inclusion Criteria:\n\n* Pregnant females ages 18 to 45 years old with singleton pregnancy, live fetus, gestational age between 32.1 and 36.7 weeks, not in labor, scheduled for routine ultrasound growth evaluation.\n* Gestational age determined by the date of the last menses, and confirmed by measurement of the crown-rump-length on transabdominal ultrasound.\n\nExclusion Criteria:\n\n* Subjects unable to consent\n* Active Labor\n* Fetal malformations of the lungs\n* Prescription of corticosteroids prior to ultrasound evaluation\n* Pre-gestation or gestational diabetes mellitus\n* Low English proficiency, needing an interpreter",true,"FEMALE","18 Years","45 Years",{"count":20,"type":21},16,"ESTIMATED","OBSERVATIONAL","The purpose of the study is to show if it's possible to use a special kind of ultrasound called backscatter quantitative ultrasound (bQUS) to check on a baby's lungs when the mother is 36 weeks pregnant. 16 participants will be on study for a single 30 minute ultrasound between 32 and 36 weeks of pregnancy.",[25,26],"Respiratory Complication","Fetal Lung Imaging","RECRUITING","2026-06-24",{"date":30,"type":31},"2026-06-25","ACTUAL",{"date":33,"type":31},"2024-12-17",{"date":35,"type":21},"2027-06",{"name":37,"class":38},"University of Wisconsin, Madison","OTHER",1,{"id":41,"slug":42,"hasResults":11,"nctId":43,"briefTitle":44,"officialTitle":45,"acronym":4,"eligibilityCriteria":46,"healthyVolunteers":11,"sex":47,"minAge":17,"maxAge":4,"enrollmentInfo":48,"targetDuration":4,"studyType":50,"phases":51,"briefSummary":53,"conditions":54,"keywords":56,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":59,"lastUpdatePostDateStruct":60,"startDateStruct":62,"completionDateStruct":64,"leadSponsor":66,"locationsCount":39},"100505038","phase-4-a-study-to-investigate-of-the-effects-of-opioid-exposure-on-the-ability-of-the-diaphragm-muscle-100505038","NCT05856136","A Study to Investigate of the Effects of Opioid Exposure on the Ability of the Diaphragm Muscle","Investigation of the Effects of Opioid Exposure on the Ability of the Diaphragm Muscle to Generate Higher Force Behaviors","Inclusion Criteria:\n\n\\- Adult male and female patients undergoing lower extremity orthopedic surgery at the study institutions (St. Mary Hospital and Rochester Methodist Hospital within the Mayo Clinic Rochester hospital system).\n\nExclusion Criteria:\n\n* Patients who refuse research participation.\n* Patients who are pregnant.\n* Patients with known pulmonary pathology (COPD, asthma requiring routine treatment).","ALL",{"count":49,"type":21},69,"INTERVENTIONAL",[52],"PHASE4","The purpose of this study is to evaluate opioid dose effects on the ability of the diaphragm muscle to generate higher force behaviors.",[55,25],"Respiratory Function Loss",[57,58],"elastography","ultrasound","2026-06-18",{"date":61,"type":31},"2026-06-23",{"date":63,"type":31},"2023-06-19",{"date":65,"type":21},"2027-01-01",{"name":67,"class":38},"Mayo Clinic",{"id":69,"slug":70,"hasResults":11,"nctId":71,"briefTitle":72,"officialTitle":73,"acronym":4,"eligibilityCriteria":74,"healthyVolunteers":11,"sex":47,"minAge":17,"maxAge":4,"enrollmentInfo":75,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":77,"conditions":78,"keywords":4,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":79,"lastUpdatePostDateStruct":80,"startDateStruct":82,"completionDateStruct":84,"leadSponsor":86,"locationsCount":39},"100547754","lung-ultrasound-for-physiotherapy-in-hospitalized-patients-with-respiratory-complications-100547754","NCT06412081","Lung Ultrasound for Physiotherapy in Hospitalized Patients With Respiratory Complications","The Value of Point-of-care Lung Ultrasound for Physiotherapy in Hospitalized Patients With Acute Respiratory Symptoms","Inclusion Criteria:\n\n* Hospitalization in a general ward\n* Acute respiratory symptoms (\\\u003C 48h)\n* Chest X-ray available within 24h before or after the use of LUS\n\nExclusion Criteria:\n\n* Any conditions precluding the use of LUS (thoracic skin lesions, thoracic bandage, subcutaneous emphysema)\n* Inability to understand instructions due to cognitive impairment or due to language barrier",{"count":76,"type":21},30,"This study aims to evaluate the relevance of using point-of-care lung ultrasound (LUS) in modifying the physiotherapist's treatment plan for patients hospitalized in a general ward.",[25],"2026-04-22",{"date":81,"type":31},"2026-04-27",{"date":83,"type":31},"2024-05-10",{"date":85,"type":21},"2026-12-30",{"name":87,"class":38},"Cliniques universitaires Saint-Luc- Université Catholique de Louvain",{"id":89,"slug":90,"hasResults":11,"nctId":91,"briefTitle":92,"officialTitle":93,"acronym":4,"eligibilityCriteria":94,"healthyVolunteers":15,"sex":47,"minAge":17,"maxAge":4,"enrollmentInfo":95,"targetDuration":4,"studyType":50,"phases":97,"briefSummary":99,"conditions":100,"keywords":101,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":104,"lastUpdatePostDateStruct":105,"startDateStruct":107,"completionDateStruct":109,"leadSponsor":111,"locationsCount":39},"100436153","shear-wave-elastography-compared-to-respiratory-function-testing-100436153","NCT04959526","Shear-wave Elastography Compared to Respiratory Function Testing","Comparison of Shear-wave Elastography to State-of-the-art Respiratory Function Testing to Measure the Range of Forces Generated by the Diaphragm Muscle","Inclusion Criteria:\n\n\\- Adult male and female healthy volunteers.\n\nExclusion Criteria:\n\n* Volunteers who are pregnant.\n* Volunteers with known pulmonary pathology (COPD, asthma requiring routine treatment).",{"count":96,"type":21},24,[98],"NA","The purpose of this study is to evaluate the relationship between transdiaphragmatic pressure (Pdi) and diaphragm shear-wave elastography (SWE) during state-of-the-art respiratory muscle testing including volitional efforts (e.g., maximal inspiratory pressure, maximal expiratory pressure, Valsalva maneuver), as well as maximal phrenic nerve stimulation.",[55,25],[102,103],"Elastography","Ultrasound","2026-03-12",{"date":106,"type":31},"2026-03-16",{"date":108,"type":31},"2021-07-28",{"date":110,"type":21},"2026-12",{"name":67,"class":38},{"id":113,"slug":114,"hasResults":11,"nctId":115,"briefTitle":116,"officialTitle":117,"acronym":118,"eligibilityCriteria":119,"healthyVolunteers":11,"sex":47,"minAge":17,"maxAge":4,"enrollmentInfo":120,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":122,"conditions":123,"keywords":4,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":126,"lastUpdatePostDateStruct":127,"startDateStruct":129,"completionDateStruct":131,"leadSponsor":133,"locationsCount":39},"100571361","evaluation-of-gas-humidification-practices-in-patients-under-invasive-mechanical-ventilation-100571361","NCT06719258","Evaluation of Gas Humidification Practices in Patients Under Invasive Mechanical Ventilation","Evaluation of Gas Humidification Practices in Patients Under Invasive Mechanical Ventilation: Benefit of the F & P950 Heated Humidifier: Comparison With the MR 850 on Clinical Events of Under-humidification","FP950","Inclusion Criteria:\n\n* ≥ 18 years old\n* Admitted to intensive care\n* Under invasive mechanical ventilation with the usual indications for the use of a heated humidifier (prolonged invasive mechanical ventilation and \u002F or protective ventilation requiring high respiratory rates.\n\nExclusion Criteria:\n\n* Mechanical venitilation immediately after surgery (\\\u003C24h)\n* Imminent extubation or planned intubation of very short duration (\\\u003C24h)\n* Enrolled in the SAVE-ICU study in the group receiving volatile agents with the AnaConDa system.",{"count":121,"type":21},40,"When mechanical ventilation is initiated, a humidification method should be chosen. There is two methods: heat and humidity exchanger filters or heated humidity. The second method is recognized to be more efficient, but many external factors can influence its performance. Insufficient humidity results in observable problems, such as difficult management of respiratory secretions.\n\nThe study compare two heated humidifiers already used in ICU.\n\nData will be collected retrospectively from June 1, 2021.",[124,125,25],"Humidifier Lung","Mechanical Fragility","2025-08-27",{"date":128,"type":31},"2025-08-28",{"date":130,"type":31},"2024-09-20",{"date":132,"type":21},"2026-07",{"name":134,"class":38},"Laval University",{"id":136,"slug":137,"hasResults":11,"nctId":138,"briefTitle":139,"officialTitle":140,"acronym":4,"eligibilityCriteria":141,"healthyVolunteers":11,"sex":47,"minAge":17,"maxAge":4,"enrollmentInfo":142,"targetDuration":144,"studyType":22,"phases":4,"briefSummary":145,"conditions":146,"keywords":148,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":33,"lastUpdatePostDateStruct":158,"startDateStruct":160,"completionDateStruct":162,"leadSponsor":164,"locationsCount":39},"100573323","advanced-prediction-of-respiratory-depression-episode-using-the-linshom-continuous-predictive-respiratory-sensor-100573323","NCT06744790","Advanced Prediction of Respiratory Depression Episode Using the Linshom Continuous Predictive Respiratory Sensor","Linshom Continuous Predictive Respiratory Monitor (CPRM) for Prediction of Patient Respiratory Decline","Inclusion Criteria:\n\n* ≥18 years old undergoing non-cardiac surgery\n* Post-operative patients admitted to the PACU and expected to stay in the hospital for at least overnight\n* Receiving supplemental oxygen via face mask in the PACU\n* On continuous SpO2 saturation monitoring\n* Receiving standard postoperative of care\n\nExclusion Criteria:\n\n* Requirement for any form of postoperative invasive ventilatory support\n* Patients receiving only local or topical anesthesia\n* Day\u002Foutpatient surgery\n* Unable to cooperate with the application of the study device\n* Surgical\u002Fnursing\u002Fanesthesia staff suggest no study-related monitoring because of medical situation",{"count":143,"type":21},320,"1 Year","Investigators will enroll 320 patients who will undergo non-cardiac surgery, receive supplemental oxygen via face mask, and will be on a continuous pulse oximetry monitor in the Post Anesthesia Care Unit (PACU). The enrollment criteria were adapted from a previous study that showed SpO2 values seriously underestimated the severity of post-operative hypoxemia in patients with and without specific risk factors for hypoxemia. Research personnel will screen and ensure that each subject meets the enrollment criteria, and the informed consent is properly executed. Upon arrival to the PACU, each subject will be fitted with oxygen mask containing the Linshom sensor, which will be connected to a Linshom monitor for data collection. A side stream capnography line will be connected to the same face mask and the capnography data will be collected on the Zoe Medical 740 SELECT™ monitor. Additionally, two pulse oximeters will be applied to the same hand (non- NIBP arm), one of which will be connected to a hospital monitor (SoC) and the other to a Zoe Medical 740 SELECT™ monitor. The Linshom and 740 SELECT™ monitors will collect data once every second.\n\nResearch personnel will then initiate the Linshom CPRM baseline mode and begin recording any clinical intervention (e.g., medications, oxygen delivery change, and stimulation upon detection of changes in patient's condition) that is performed by the PACU staff, paying close attention to, and recording of time at which those interventions occurred. Data collection will be performed throughout the subject's entire PACU stay. The CPRM data collection will be performed passively while the patient is monitored via SoC and will not interfere with clinical interventions that may take place during the data collection. Clinical staff in the PACU will be blinded to the Linshom CPRM data as well as pulse oximetry (non-SOC monitor) and capnography data collected.",[147,25],"Post Surgical Respiratory Failure",[149,25,150,147,151,152,153,154,155,156,157],"Respiratory Decline","Respiratory Depression","Continuous Monitoring","Continuous Respiratory Monitoring","respiratory","monitoring","pulse oximetry","capnography","Linshom",{"date":159,"type":31},"2024-12-20",{"date":161,"type":31},"2023-06-21",{"date":163,"type":21},"2025-06-16",{"name":165,"class":166},"Linshom Medical, Inc.","INDUSTRY",{"id":168,"slug":169,"hasResults":11,"nctId":170,"briefTitle":171,"officialTitle":172,"acronym":173,"eligibilityCriteria":174,"healthyVolunteers":11,"sex":47,"minAge":4,"maxAge":175,"enrollmentInfo":176,"targetDuration":4,"studyType":50,"phases":178,"briefSummary":179,"conditions":180,"keywords":4,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":184,"lastUpdatePostDateStruct":185,"startDateStruct":187,"completionDateStruct":189,"leadSponsor":191,"locationsCount":39},"100550164","respiratory-trends-during-blood-transfusions-in-newborns-100550164","NCT06443515","Respiratory Trends During Blood Transfusions in Newborns.","Evaluation of Respiratory Trends During Blood Transfusions in Newborns.","ARTE","Inclusion Criteria:\n\n* admitted newborns requiring blood transfusions as per local practice and\u002For international guidelines\n\nExclusion Criteria:\n\n* newborns with major malformations\n* need for palliative care\n* lack of informed consent","1 Month",{"count":177,"type":21},71,[98],"The prevalence of transfusion reactions is between 1 and 11% of transfusions. Most reactions are mild and do not pose a life-threatening risk to the patient. More serious problems may be the only manifestations that lead to suspicion of a transfusion reaction.\n\nMost noninfectious transfusion reactions are immune-mediated. Two main types of reactions can be distinguished: TACO (transfusion associated cardiac overload, which is a cardiogenic pulmonary edema) and TRALI (transfusion related acute lung injury, non-cardiogenic pulmonary edema).\n\nAlthough TRALI are diagnoses of exclusion, the presence of noncardiogenic pulmonary edema and respiratory problems in the vicinity of blood product transfusions should raise suspicion. Other signs of TRALI are hypotension and tachycardia, while in TACO arterial hypertension with positive water balance can be observed.\n\nAccording to previous reports, the prevalence of transfusion reactions in the neonatal population is approximately 8%. Factors associated with these reactions are low birth weight and low gestational age. However, diagnostic criteria of respiratory transfusion reactions are not uniform across studies, and often the generic terms \"acute lung injury\" have been used.\n\nTherefore, the primary objective of this study is to evaluate the respiratory trend during blood transfusions; secondary objectives are the study of risk factors for the development of respiratory worsening and the possible association with complications.",[181,182,25,183],"Blood Transfusion Complication","Blood Transfusion Associated Adverse Reactions","Respiratory Morbidity","2024-09-23",{"date":186,"type":31},"2024-09-24",{"date":188,"type":31},"2024-07-01",{"date":190,"type":21},"2026-01-15",{"name":192,"class":38},"Fondazione Policlinico Universitario Agostino Gemelli IRCCS"]