[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"respiratory-effort-related-arousal-x7c-patient-x7c-respiratory-measures-and-ventilator-management\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:respiratory-effort-related-arousal-x7c-patient-x7c-respiratory-measures-and-ventilator-management":29},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":30,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":37,"lastUpdatePostDateStruct":38,"startDateStruct":41,"completionDateStruct":43,"leadSponsor":45,"locationsCount":5},"100554063","comparison-of-different-methods-to-calculate-pendelluft-by-electrical-impedance-tomography-in-mechanically-ventilated-patients-100554063",false,"NCT06494215","Comparison of Different Methods to Calculate Pendelluft by Electrical Impedance Tomography in Mechanically Ventilated Patients","Comparison of Different Methods to Calculate Pendelluft by Electrical Impedance Tomography in Patients Undergoing Invasive Mechanical Ventilation Under Pressure Support Mode","Inclusion Criteria:\n\n* Patients under invasive mechanical ventilation intubated due to respiratory failure in pressure support mode (weaning phase)\n\nExclusion Criteria:\n\n* Age less than 18 years; sedation or neuromuscular blockade; absence of respiratory effort; contraindications to esophageal balloon cathether positioning or electrical impedance tomography belt positioning; presence of pneumothorax or active air leaks; hemodynamic instability; absence of informed consent.","ALL","18 Years",{"count":19,"type":20},15,"ESTIMATED","INTERVENTIONAL",[23],"NA","The Pendelluft phenomenon is an important cause of lung damage in spontaneously breathing mechanically ventilated patients since it considerably increases the stress on the lung parenchyma in the dependent areas. It can result in a local driving pressure up to three times higher than the global driving pressure. The measurement of Pendelluft is still uncertain in the literature, and although various methods have been proposed, not all have the same meaning in terms of pulmonary overstress and overstrain. This study proposes a comparative analysis of different ways to calculate and estimate the stress imposed on the lung parenchyma by Pendelluft in terms of regional volume and local driving pressure through electrical impedance tomography.",[26,27,28,29],"Asynchrony, Patient-Ventilator","ARDS","Respiratory Insufficiency","Respiratory Effort-Related Arousal | Patient | Respiratory Measures and Ventilator Management",[31,32,33,27,34,35],"Pendelluft","Ventilator-patient asynchrony","Patient self-induced lung injury","Respiratory failure","Electrical Impedance Tomography","RECRUITING","2024-07-02",{"date":39,"type":40},"2024-07-10","ACTUAL",{"date":42,"type":40},"2024-06-11",{"date":44,"type":20},"2025-06-11",{"name":46,"class":47},"University of Sao Paulo General Hospital","OTHER"]