[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"respiratory-function\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:respiratory-function":30},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,6,0,[8,51,81,104,131,159],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":31,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":39,"lastUpdatePostDateStruct":40,"startDateStruct":43,"completionDateStruct":45,"leadSponsor":47,"locationsCount":50},"100641050","effects-of-core-and-inspiratory-muscle-training-on-muscle-oxygenation-and-athletic-performance-n-young-soccer-players-100641050",false,"NCT07657065","Effects of Core and Inspiratory Muscle Training on Muscle Oxygenation and Athletic Performance İn Young Soccer Players","Effects of Core and Inspiratory Muscle Training On Muscle Oxygenation and Athletic Performance İn Young Soccer Players","Inclusion Criteria:\n\n* Being between 15 and 18 years of age.\n* Being a male soccer player.\n* Actively and regularly participating in trainings at Alagöz Soccer Club.\n* Having participated in regular soccer training for at least the last 6 months.\n* Being able to continue routine trainings throughout the study period.\n* Being fully informed about the research.\n* Having obtained voluntary informed consent, and parental\u002Fguardian consent for participants under 18 years of age.\n* Having the cognitive and physical capacity to understand and fulfill the specific test and exercise instructions.\n\nExclusion Criteria:\n\n* Having a history of lower extremity, trunk-core, or athletic performance-limiting injury within the last 6 months.\n* Having undergone orthopedic lower extremity or spine surgery within the last 1 year.\n* Having active musculoskeletal pain or any orthopedic\u002Fneurological condition that prevents exercise.\n* Having any health condition that prevents the safe execution of balance, sprint, agility, jump, or core endurance tests.\n* Having asthma, chronic respiratory system diseases, exercise-induced bronchospasm, cardiovascular disease, or a physician-imposed restriction on high-intensity exercise that could affect respiratory muscle or exercise testing.\n* Having open wounds, infections, or severe skin sensitivity that prevents the application of sensors placed on the skin.\n* Currently participating in another structured respiratory muscle training or structured core exercise program that could affect the study results.\n* Having a body mass index (BMI) of 30 kg\u002Fm² or above.\n* Being deemed unsuitable for the study by the researcher due to safety concerns.\n* Withdrawal from the study at the request of the participant or their parent\u002Fguardian.\n* Missing two consecutive exercise sessions or having an insufficient overall attendance rate.\n* Developing an exercise-preventing injury or illness during the study period.\n* Occurrence of any safety risk during testing or exercise sessions.\n* Non-compliance with the study protocol.\n* Starting another additional exercise program during the study.\n* Technical inability to obtain reliable measurement data.",true,"MALE","15 Years","18 Years",{"count":21,"type":22},54,"ESTIMATED","INTERVENTIONAL",[25],"NA","The purpose of this randomized controlled trial is to investigate the effects of core training and inspiratory muscle training (IMT) on muscle oxygenation and athletic performance in youth male soccer players aged 15-18. A total of 54 healthy soccer players will be included and randomly assigned into three equal groups: the Control Group, the Core Training Group, and the Core Training + IMT Group.\n\nAll interventions will be implemented for 8 weeks in addition to routine soccer training sessions. Assessments will be performed at baseline (Week 0), mid-intervention (Week 4), and post-intervention (Week 8). The primary outcome measures of the study are aerobic capacity assessed by the Yo-Yo Intermittent Recovery Test Level 1 and muscle oxygenation parameters monitored via near-infrared spectroscopy (NIRS) using a MOXY monitor. Secondary outcome measures include sprint performance, agility, dynamic balance, core muscle strength and endurance, inspiratory muscle strength, lower extremity explosive power, and soccer-specific technical performance tests.\n\nOverall, this study aims to reveal the combined effects of core training and inspiratory muscle training on muscle oxygenation, respiratory functions, aerobic capacity, and soccer performance, while explaining the underlying physiological mechanisms in youth athletes.",[28,29,30],"Athletic Performance","Muscle Oxygenation","Respiratory Function",[32,33,34,35,36,37],"Youth Soccer","Core Training","Inspiratory Muscle Training","Near-Infrared Spectroscopy","Aerobic Capacity","Diaphragm","NOT_YET_RECRUITING","2026-06-17",{"date":41,"type":42},"2026-06-18","ACTUAL",{"date":44,"type":22},"2026-08",{"date":46,"type":22},"2027-12",{"name":48,"class":49},"Istinye University","OTHER",1,{"id":52,"slug":53,"hasResults":11,"nctId":54,"briefTitle":55,"officialTitle":56,"acronym":4,"eligibilityCriteria":57,"healthyVolunteers":16,"sex":58,"minAge":59,"maxAge":60,"enrollmentInfo":61,"targetDuration":4,"studyType":23,"phases":63,"briefSummary":64,"conditions":65,"keywords":68,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":73,"lastUpdatePostDateStruct":74,"startDateStruct":75,"completionDateStruct":77,"leadSponsor":79,"locationsCount":50},"100641289","effects-of-diaphragmatic-breathing-during-equipment-based-pilates-in-women-100641289","NCT07652229","Effects of Diaphragmatic Breathing During Equipment-Based Pilates in Women","The Effects of Diaphragmatic Breathing Exercises on Core Stabilization Muscle Strength, Peak Expiratory Flow, and Chest Expansion in Women Performing Equipment-Based Pilates: A Randomized Controlled Trial","Inclusion Criteria:\n\nFemale participants aged 20-50 years. Healthy individuals regularly performing equipment-based Pilates exercises. Willingness to participate voluntarily and provide informed consent. Ability to attend Pilates sessions twice weekly for 8 weeks.\n\nExclusion Criteria:\n\nHistory of spinal trauma or surgery within the previous 6 months. Pregnancy. Diabetes mellitus or other systemic diseases. Respiratory or musculoskeletal disorders that may affect participation or outcome measurements.\n\nCognitive or physical limitations preventing compliance with the study protocol.\n\nFailure to attend scheduled sessions or complete the intervention protocol. Development of pain, injury, or any medical condition requiring discontinuation during the study.","FEMALE","20 Years","50 Years",{"count":62,"type":22},44,[25],"This randomized controlled study aims to investigate the effects of diaphragmatic breathing exercises on core stabilization muscle strength, peak expiratory flow (PEF), and chest expansion in women performing equipment-based Pilates.\n\nA total of 44 healthy women aged 20 to 50 years who regularly participate in equipment-based Pilates exercises will be recruited and randomly assigned to one of two groups. The intervention group will receive equipment-based Pilates training combined with diaphragmatic breathing exercises, while the control group will receive equipment-based Pilates training only.\n\nBoth groups will participate in supervised exercise sessions twice weekly for 8 weeks. Core stabilization muscle strength, peak expiratory flow, and chest expansion measurements will be assessed before and after the intervention period.\n\nThe findings of this study may contribute to a better understanding of the additional effects of diaphragmatic breathing exercises on respiratory function and core stabilization in women performing Pilates.",[66,30,67],"Core Stability","Diaphragmatic Breathing",[69,70,67,66,71,72,30],"Pilates","Equipment-Based Pilates","Peak Expiratory Flow","Chest Expansion","2026-06-16",{"date":41,"type":42},{"date":76,"type":22},"2026-06-15",{"date":78,"type":22},"2026-08-15",{"name":80,"class":49},"Istanbul Aydın University",{"id":82,"slug":83,"hasResults":11,"nctId":84,"briefTitle":85,"officialTitle":86,"acronym":4,"eligibilityCriteria":87,"healthyVolunteers":16,"sex":17,"minAge":19,"maxAge":88,"enrollmentInfo":89,"targetDuration":4,"studyType":91,"phases":4,"briefSummary":92,"conditions":93,"keywords":4,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":96,"lastUpdatePostDateStruct":97,"startDateStruct":99,"completionDateStruct":101,"leadSponsor":103,"locationsCount":4},"100637638","respiratory-function-and-athletic-performance-in-professional-soccer-players-100637638","NCT07617116","Respiratory Function and Athletic Performance in Professional Soccer Players","Association Between Respiratory Function and Athletic Performance Parameters in Professional Soccer Players: A Cross-Sectional Study","Inclusion Criteria:\n\n* Participants will be actively competing, licensed professional soccer players. -Participants will be engaged in regular, team-based training and competitive match schedules.\n* Participants will voluntarily provide written informed consent before any study-related physical performance assessments are conducted.\n\nExclusion Criteria:\n\n* Participants will be excluded if they present with an acute upper or lower respiratory tract infection that could potentially affect pulmonary function or maximal respiratory muscle performance.\n* Participants will be excluded if they have a documented history of major cardiothoracic surgery.\n* Participants will be excluded if they have any diagnosed respiratory and\u002For cardiovascular disorder associated with dyspnea or impaired pulmonary mechanics.\n* Participants will be excluded if they present with any condition that elevates clinical risk during maximal inspiratory and expiratory pressure assessments.\n* Participants will be excluded if they have sustained an acute musculoskeletal injury within the preceding 6 weeks that could compromise maximal physical exertion during sport-specific performance testing.","35 Years",{"count":90,"type":22},31,"OBSERVATIONAL","This prospective observational study aims to investigate the relationship between respiratory function and multidimensional athletic performance parameters in professional soccer players. The primary hypothesis of the study is that soccer players with enhanced respiratory function and superior respiratory muscle strength will exhibit optimized motor performance outcomes and shorter (faster) reactive reaction times. Investigators will evaluate respiratory muscle strength, spirometric pulmonary functions, dynamic balance, core and abdominal endurance, and reactive visuomotor reaction times during a single testing session within the competitive season.",[30,94,28,95],"Respiratory Muscle Strength","Reaction Time","2026-05-23",{"date":98,"type":42},"2026-06-01",{"date":100,"type":22},"2026-05-25",{"date":102,"type":22},"2026-07-10",{"name":48,"class":49},{"id":105,"slug":106,"hasResults":11,"nctId":107,"briefTitle":108,"officialTitle":109,"acronym":4,"eligibilityCriteria":110,"healthyVolunteers":11,"sex":111,"minAge":19,"maxAge":112,"enrollmentInfo":113,"targetDuration":115,"studyType":91,"phases":4,"briefSummary":116,"conditions":117,"keywords":4,"overallStatus":121,"whyStopped":4,"lastUpdateSubmitDate":122,"lastUpdatePostDateStruct":123,"startDateStruct":125,"completionDateStruct":127,"leadSponsor":129,"locationsCount":50},"100633225","functional-and-respiratory-determinants-of-long-term-colorectal-cancer-outcomes-100633225","NCT07523919","Functional and Respiratory Determinants of Long-Term Colorectal Cancer Outcomes","The Impact of Functional Status and Respiratory Parameters on Long-Term Outcomes in Colorectal Cancer","Inclusion Criteria:\n\n* Age between 18 and 80 years\n* Voluntary participation in the study\n\nExclusion Criteria:\n\n* Presence of musculoskeletal disorders that may prevent completion of the required tests\n* Presence of cognitive impairment\n* History of psychiatric disease\n* History of major surgery","ALL","80 Years",{"count":114,"type":22},52,"2 Years","Colorectal cancer is one of the most commonly diagnosed malignancies worldwide and a leading cause of cancer-related morbidity and mortality. Its global incidence continues to increase, with a substantial proportion of cases diagnosed at advanced stages, which adversely affects prognosis. Patients diagnosed at an early stage and treated with surgery have significantly better long-term survival outcomes. Five-year survival rates are approximately 90% for stage I disease, decreasing to around 70% in stage II and 60% in stage III, and dropping to as low as 8% in stage IV disease.\n\nAdvanced age, family history, and environmental exposures are well-established risk factors for colorectal cancer. In addition, modifiable lifestyle factors-including smoking, physical inactivity, unhealthy dietary patterns, and obesity-have been shown to significantly increase the risk of disease.\n\nAlthough surgical resection remains the cornerstone of curative treatment in colorectal cancer, long-term outcomes are influenced not only by tumor stage but also by various patient-related factors, including comorbidities, functional capacity, and respiratory reserve. Functional status, which reflects a patient's ability to perform activities of daily living, is a key determinant of postoperative recovery and long-term outcomes. Reduced functional capacity has been associated with poorer long-term survival, diminished quality of life, and increased late morbidity. Therefore, objective preoperative assessment of functional status is considered essential for predicting long-term prognosis.\n\nRespiratory function also plays a critical role, particularly in patients undergoing abdominal surgery. Impaired pulmonary capacity increases the risk of postoperative pulmonary complications, prolongs hospital stay, and may indirectly affect long-term survival. However, studies evaluating the impact of preoperative respiratory parameters on long-term outcomes in patients with colorectal cancer remain limited. Furthermore, comprehensive analyses integrating both functional capacity and respiratory function are scarce in the current literature. Therefore, further investigation in this area is warranted.\n\nThe aim of this study is to evaluate the impact of functional status and respiratory parameters on long-term clinical outcomes in patients with colorectal cancer.\n\nH0: There is no statistically significant association between functional status, respiratory parameters, and long-term clinical outcomes in patients with colorectal cancer.\n\nH1: There is a statistically significant association between functional status, respiratory parameters, and long-term clinical outcomes in patients with colorectal cancer.",[118,30,119,120],"Colorectal Cancer","Functional Status","Long Term","RECRUITING","2026-04-05",{"date":124,"type":42},"2026-04-13",{"date":126,"type":42},"2026-03-10",{"date":128,"type":22},"2028-03-10",{"name":130,"class":49},"Inonu University",{"id":132,"slug":133,"hasResults":11,"nctId":134,"briefTitle":135,"officialTitle":135,"acronym":4,"eligibilityCriteria":136,"healthyVolunteers":16,"sex":111,"minAge":137,"maxAge":4,"enrollmentInfo":138,"targetDuration":4,"studyType":23,"phases":140,"briefSummary":141,"conditions":142,"keywords":144,"overallStatus":121,"whyStopped":4,"lastUpdateSubmitDate":151,"lastUpdatePostDateStruct":152,"startDateStruct":153,"completionDateStruct":155,"leadSponsor":157,"locationsCount":50},"100633074","the-effects-of-a-mindfulness-program-on-running-performance-respiratory-function-and-heart-rate-variability-100633074","NCT07521956","The Effects of a Mindfulness Program on Running Performance, Respiratory Function, and Heart Rate Variability","Inclusion Criteria:\n\n* Must pass the Get Active Questionnaire to assess physical activity risk\n* Must regularly engage in recreational running for between 30 and 520 minutes per week\n\nExclusion Criteria:\n\n* Running more than 520 minutes per week","19 Years",{"count":139,"type":22},20,[25],"Broadly, the objective of the research is to evaluate the effectiveness of a specific breathwork program (Les Mills Breath) on various physiological variables related to running performance, compared to a mindfulness control (20 minutes of guided meditation). There are three specific research questions: 1) Does daily participation in a 20-minute breathwork program improve respiratory function more than a mindfulness control intervention? 2) Does daily participation in a 20-minute breathwork program improve heart rate variability (an indicator of parasympathetic nervous system activity which is associated with enhanced exercise recovery) more than a mindfulness control intervention? 3) Does daily participation in a 20-minute breathwork program increase self-selected running speeds at relative moderate and vigorous intensities more than a mindfulness control intervention? The intended outcomes of the current research are to contribute to the field of research which has examined various forms of \"respiratory training\" and their effects on athletic performance, specifically running. While certain training protocols have been shown to be effective, there are issues of accessibility which persist. Methods of respiratory training\u002Fbreathwork which are more easily available to recreational athletes are understudied with regards to running performance, hence the current research.",[30,143],"Runners",[145,146,147,148,149,150],"respiratory function","running performance","heart rate variability","mindfulness","breathwork","meditation","2026-04-03",{"date":124,"type":42},{"date":154,"type":42},"2026-01-19",{"date":156,"type":22},"2026-12",{"name":158,"class":49},"University of the Fraser Valley",{"id":160,"slug":161,"hasResults":11,"nctId":162,"briefTitle":163,"officialTitle":164,"acronym":4,"eligibilityCriteria":165,"healthyVolunteers":16,"sex":111,"minAge":115,"maxAge":166,"enrollmentInfo":167,"targetDuration":169,"studyType":91,"phases":4,"briefSummary":170,"conditions":171,"keywords":174,"overallStatus":121,"whyStopped":4,"lastUpdateSubmitDate":151,"lastUpdatePostDateStruct":180,"startDateStruct":182,"completionDateStruct":184,"leadSponsor":186,"locationsCount":50},"100617807","effects-of-different-inspiratoryexpiratory-ratios-on-respiratory-and-recovery-outcomes-during-dental-procedures-under-general-anesthesia-in-pediatric-patients-100617807","NCT07323420","Effects of Different Inspiratory:Expiratory Ratios on Respiratory and Recovery Outcomes During Dental Procedures Under General Anesthesia in Pediatric Patients","A Clinical Study on the Effects of Different Inspiratory:Expiratory Ratios on Respiratory Function and Recovery in Pediatric Patients Undergoing Dental Procedures Under General Anesthesia","Inclusion Criteria:\n\n* Pediatric patients scheduled for dental procedures under general anesthesia at our faculty.\n* American Society of Anesthesiologists (ASA) Physical Status I or II.\n* Age between 2 and 12 years.\n* Written informed consent obtained from parents or legal guardians.\n\nExclusion Criteria:\n\n* Patients whose parents or legal guardians decline participation.\n* Presence of adenoid hypertrophy \\>30%.\n* Macroglossia or retrognathia.\n* Severe obesity or developmental delay.\n* History of delayed emergence from anesthesia.\n* ASA Physical Status III or higher.\n* Anesthesia duration less than 1 hour or more than 3 hours.\n* Patients with difficult airway management or ventilation.\n* Known pulmonary or airway diseases or anomalies.\n* Use of pharmacological agents that may affect spontaneous respiratory quality.\n* Presence of neuromuscular disorders affecting respiratory function.\n* Age \\\u003C2 years or \\>12 years.\n* Administration of medications intraoperatively or preoperatively that may influence respiratory dynamics during emergence (e.g., atropine, lidocaine, steroids).","12 Years",{"count":168,"type":22},75,"1 Day","This observational study aims to evaluate the effects of different inspiratory to expiratory (I:E) ratios (1:2 vs. 1:3) during mechanical ventilation in pediatric patients undergoing dental procedures under general anesthesia. Due to behavioral challenges, dental phobia, or medical conditions, general anesthesia is often required to ensure immobility and cooperation during dental treatments in children.\n\nIn the clinic where the study will be conducted, the I:E ratio is routinely adjusted approximately 20-30 minutes before the end of the procedure to facilitate a smoother transition to spontaneous breathing during emergence from anesthesia. While 1:2 is commonly used, the 1:3 ratio may improve respiratory efficiency and recovery by prolonging the expiratory phase.\n\nThe study aims to compare vital signs, respiratory parameters (heart rate, blood pressure, SpO₂, EtCO₂, respiratory rate), recovery quality, and respiratory complications between the two I:E ratios. The findings aim to optimize ventilation strategies and improve patient comfort and safety during emergence from anesthesia.",[30,172,173],"Pediatric Anesthesia","General Anesthesia",[173,175,176,177,178,179],"Anesthesia Recovery","Emergence from Anesthesia","Mechanical Ventilation","I:E Ratio","Recovery Quality",{"date":181,"type":42},"2026-04-09",{"date":183,"type":42},"2026-04-01",{"date":185,"type":22},"2026-11-30",{"name":187,"class":49},"Kırıkkale University"]