[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"retrograde-intrarenal-surgery\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:retrograde-intrarenal-surgery":24},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,43,75],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":4,"briefSummary":22,"conditions":23,"keywords":25,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":31,"lastUpdatePostDateStruct":32,"startDateStruct":35,"completionDateStruct":37,"leadSponsor":39,"locationsCount":42},"100644065","general-versus-spinal-anesthesia-in-rirs-100644065",false,"NCT07664384","General Versus Spinal Anesthesia in RIRS","Comparative Study of General Versus Spinal Anesthesia in Retrograde Intrarenal Surgery: Impact of Stone Size on Perioperative Outcomes","Inclusion Criteria:\n\n* Adult patients (≥18 years) scheduled for elective RIRS for renal stones \\\u003C2 cm.\n* Written informed consent obtained.\n\nExclusion Criteria:\n\n* History of previous ureteral surgery or known ureteral stricture.\n* Multiple or bilateral renal stones requiring staged procedures.","ALL","18 Years",{"count":19,"type":20},80,"ESTIMATED","OBSERVATIONAL","The impact of anesthesia type on Retrograde Intrarenal Surgery (RIRS) outcomes remains a subject of ongoing debate. Several studies have compared general anesthesia (GA) and spinal anesthesia (SA) in endourological procedures, with conflicting results regarding operative time, complication rates, and stone-free outcomes. Importantly, the interaction between anesthesia type and stone characteristics-particularly stone size-has not been fully elucidated. Therefore, this study aims to conduct a retrospective comparative analysis of general versus spinal anesthesia in patients undergoing RIRS at Qena University Hospital, with particular emphasis on the effect of stone size stratification on perioperative outcomes.",[24],"Retrograde Intrarenal Surgery",[26,27,28,29],"RIRS","Spinal Anesthesia","General Anesthesia","Perioperative Outcomes","NOT_YET_RECRUITING","2026-06-22",{"date":33,"type":34},"2026-06-25","ACTUAL",{"date":36,"type":20},"2026-07",{"date":38,"type":20},"2026-09",{"name":40,"class":41},"South Valley University","OTHER",1,{"id":44,"slug":45,"hasResults":11,"nctId":46,"briefTitle":47,"officialTitle":48,"acronym":49,"eligibilityCriteria":50,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":51,"targetDuration":4,"studyType":53,"phases":54,"briefSummary":56,"conditions":57,"keywords":60,"overallStatus":65,"whyStopped":4,"lastUpdateSubmitDate":66,"lastUpdatePostDateStruct":67,"startDateStruct":69,"completionDateStruct":71,"leadSponsor":73,"locationsCount":5},"100640042","phase-2-tamsulosin-and-intraureteral-aminophylline-for-ureteral-access-during-rirs-100640042","NCT07623876","Tamsulosin and Intraureteral Aminophylline for Ureteral Access During RIRS","Comparative Efficacy of Tamsulosin, Intraureteral Aminophylline, and Their Combination in Facilitating Ureteral Access During Retrograde Intrarenal Surgery: A Multicenter Randomized Controlled Trial.","TAM-AMIN-UAS","Inclusion Criteria:\n\n* Age 18 years or older.\n* Unilateral renal stone 2 cm or less in maximal diameter on preoperative imaging.\n* Scheduled for primary retrograde intrarenal surgery.\n* Ability to provide written informed consent.\n\nExclusion Criteria:\n\n* Prior ureteral stenting on the study side.\n* Bilateral same-session retrograde intrarenal surgery.\n* Concomitant ureteral stone requiring primary semirigid ureteroscopy as the main procedure.\n* Known ureteral stricture or prior ureteral reconstructive surgery on the study side.\n* Active urinary tract infection or untreated positive urine culture.\n* Pregnancy.\n* Known allergy or contraindication to tamsulosin or aminophylline.\n* Significant cardiac arrhythmia, uncontrolled ischemic heart disease, seizure disorder, or hyperthyroidism.\n* Severe hepatic impairment.\n* Inability to comply with the 7-day preoperative medication protocol.",{"count":52,"type":20},322,"INTERVENTIONAL",[55],"PHASE2","This multicenter randomized controlled trial will evaluate whether preoperative tamsulosin, intraureteral aminophylline, or their combination can improve ureteral access during primary retrograde intrarenal surgery for renal stones. Adult patients with unilateral renal stones measuring 2 cm or less and planned placement of a 10\u002F12 Fr ureteral access sheath will be randomly assigned to one of four groups in a 2x2 factorial design. Participants will receive either tamsulosin or placebo for 7 days before surgery and either intraureteral aminophylline or intraureteral placebo during the procedure. The main outcome will be successful first-attempt placement of the planned 10\u002F12 Fr ureteral access sheath after study solution instillation, without active ureteral dilatation, sheath downsizing, prestenting with deferred surgery, or abandonment of the procedure due to access failure.",[58,24,59],"Renal Stones","Ureteral Access Sheath Placement",[61,62,63,64],"Retrograde intrarenal surgery","Tamsulosin","Intraureteral aminophylline","ureteral access sheath","RECRUITING","2026-05-28",{"date":68,"type":34},"2026-06-03",{"date":70,"type":34},"2026-05-06",{"date":72,"type":20},"2027-05",{"name":74,"class":41},"Beni-Suef University",{"id":76,"slug":77,"hasResults":11,"nctId":78,"briefTitle":79,"officialTitle":80,"acronym":4,"eligibilityCriteria":81,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":82,"targetDuration":4,"studyType":53,"phases":84,"briefSummary":86,"conditions":87,"keywords":4,"overallStatus":65,"whyStopped":4,"lastUpdateSubmitDate":89,"lastUpdatePostDateStruct":90,"startDateStruct":92,"completionDateStruct":94,"leadSponsor":96,"locationsCount":42},"100577204","homework-in-retrograde-intrarenal-surgery-100577204","NCT06795256","Homework in Retrograde Intrarenal Surgery","Homework to Help with Stone Dissolution in Retrograde Intrarenal Surgery","Inclusion Criteria:\n\n* Patients with an indication for RIRC\n\nExclusion Criteria:\n\n* Patients with anatomic abnormalities such as horseshoe kidney, fragments in the calyx diverticulum, infundibular stenosis, pelvi-ureteral junction obstruction or ureteral stenosis.\n* Patients with morbid obesity, uncontrolled hypertension, previous cerebrovascular accident, skeletal deformity such as significant coronary artery disease or symptomatic gastro-esophageal reflux disease.\n* Patients with lumbar disc herniation who have undergone spinal surgery and are unable to undergo behavioral therapy.",{"count":83,"type":20},200,[85],"NA","To evaluate the effectiveness of this homework on stone clearance rates after retrograde intrarenal surgery (RIRS) by instructing the patient in the home environment and suggesting percussion and movement\u002Fposition changes to assist in spontaneous stone passage.",[24,88],"Stone, Kidney","2025-01-27",{"date":91,"type":34},"2025-01-29",{"date":93,"type":34},"2025-01-21",{"date":95,"type":20},"2025-11-30",{"name":97,"class":41},"Adiyaman University"]