[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"rhinectomy\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:rhinectomy":26},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,48],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":23,"conditions":24,"keywords":27,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":37,"lastUpdatePostDateStruct":38,"startDateStruct":41,"completionDateStruct":42,"leadSponsor":44,"locationsCount":47},"100644707","functional-and-aesthetic-comparison-of-surgical-nasal-reconstruction-versus-nasal-prosthesis-epithesis-after-total-or-subtotal-nasal-amputation-100644707",false,"NCT07674030","Functional and Aesthetic Comparison of Surgical Nasal Reconstruction Versus Nasal Prosthesis (Epithesis) After Total or Subtotal Nasal Amputation","Comparison of Epithesis and Surgical Nasal Reconstruction Using the SCHNOS Score","CERNAS","Inclusion Criteria:\n\n* Patients aged 18 years or older\n* Patients who have undergone total or subtotal nasal amputation (defined as loss of at least three nasal subunits, or of two subunits including the dorsum) and who have been rehabilitated either by surgical reconstruction or by nasal epithesis for more than one year\n\nExclusion Criteria:\n\n* Ongoing tumour progression or tumour recurrence\n* Non-French-speaking patients\n* Patients under legal protection measures (guardianship, legal safeguarding, limited or full legal incapacity)\n* Patients unlikely to cooperate with the study (e.g. presenting with a psychiatric disorder)","ALL","18 Years",{"count":20,"type":21},20,"ESTIMATED","OBSERVATIONAL","CERNAS is a prospective, multicenter, non-interventional study comparing the functional and aesthetic outcomes of two rehabilitation strategies after total or subtotal nasal amputation: surgical reconstruction (primarily paramedian forehead flap or free flap) versus nasal epithesis (prosthesis). Patients who have undergone either rehabilitation at least one year prior to enrolment will be invited to complete the validated French version of the SCHNOS (Standardized Cosmesis and Health Nasal Outcomes Survey) questionnaire. The study aims to provide an objective, patient-reported comparison of these two options to guide future clinical decision-making.",[25,26],"Nose Cancer","Rhinectomy",[28,29,30,31,32,33,34,35],"Total rhinectomy","Nasal reconstruction","Nasal prosthesis","SCHNOS","Nasal amputation","Quality of life","Free flap","Forehead flap","NOT_YET_RECRUITING","2026-06-29",{"date":39,"type":40},"2026-07-01","ACTUAL",{"date":39,"type":21},{"date":43,"type":21},"2027-01-30",{"name":45,"class":46},"Hôpital NOVO","OTHER",4,{"id":49,"slug":50,"hasResults":11,"nctId":51,"briefTitle":52,"officialTitle":53,"acronym":54,"eligibilityCriteria":55,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":56,"targetDuration":58,"studyType":22,"phases":4,"briefSummary":59,"conditions":60,"keywords":64,"overallStatus":68,"whyStopped":4,"lastUpdateSubmitDate":69,"lastUpdatePostDateStruct":70,"startDateStruct":72,"completionDateStruct":74,"leadSponsor":76,"locationsCount":78},"100492513","survival-and-prognostic-factors-of-squamous-cell-carcinoma-of-the-nasal-vestibule-100492513","NCT05693116","Survival and Prognostic Factors of Squamous Cell Carcinoma of the Nasal Vestibule","Survival and Prognostic Factors of Squamous Cell Carcinoma of the Nasal Vestibule: a Multi-centre Study","NV-SCC","Inclusion Criteria:\n\n* diagnosis of squamous cell carcinoma of the nasal vestibule\n* underwent upfront surgical treatment with curative intent\n* availability of clinical and radiological data for cT reassessment\n* availability of histological samples for pT reassessment\n* follow-up of at least 6 months after surgery.\n\nExclusion Criteria:\n\n* patients initially referred for disease persistence or recurrence\n* patients affected by tumour involving the nasal vestibule but originating from other sites (eg. nasal cavities, skin of the nasal pyramid or upper lip)",{"count":57,"type":21},300,"5 Years","The goal of this observational study is to learn about survival and prognostic factors in patients who underwent surgical treatment for primary squamous cell carcinoma of the nasal vestibule. The main questions it aims to answer are:\n\n* what is the prognosis of patients affected by squamous cell carcinoma of the nasal vestibule?\n* are there any specific factors that could influence prognosis?\n* is it possible to elaborate a new staging system, able to overcome the limitations of the currently used ones? Data about patients, tumour and type of surgery performed will be collected. Participants will be followed-up for a minimum 6 months period after surgery.",[61,26,62,63],"Nasal Vestibule Carcinoma","Nasal Vestibule","Squamous Cell Carcinoma",[65,66,67],"nasal vestibule","squamous cell carcinoma","rhinectomy","RECRUITING","2023-01-11",{"date":71,"type":40},"2023-01-20",{"date":73,"type":40},"2022-12-01",{"date":75,"type":21},"2029-12",{"name":77,"class":46},"Istituto Clinico Humanitas",6]