[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"risk-factor-cardiovascular\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:risk-factor-cardiovascular":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,5,0,[8,53,95,126,146],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":23,"conditions":24,"keywords":30,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":41,"lastUpdatePostDateStruct":42,"startDateStruct":45,"completionDateStruct":47,"leadSponsor":49,"locationsCount":52},"100493719","find-stroke-recovery---a-longitudinal-study-100493719",false,"NCT05708807","FIND Stroke Recovery - A Longitudinal Study","FIND Stroke Recovery: A Longitudinal Frequent Evaluation Long-term Follow-up Study","FIND","Investigators enrol patients presenting with first-ever ischemic stroke or intracerebral haemorrhage admitted to the stroke units at the Sahlgrenska University Hospital in Gothenburg, Sweden.\n\nThe inclusion criteria are:\n\n• first-ever acute ischemic stroke; or intracerebral hemorrhage.\n\nThe exclusion criteria are:\n\n* pre-stroke mRS score of ≥3;\n* severe neurodegenerative disease, cerebral neoplasm or terminal illness; and\n* patients considered unlikely to be able to participate in or to understand and\u002For comply with study procedures during follow-up visits at the hospital.","ALL","18 Years",{"count":20,"type":21},600,"ESTIMATED","OBSERVATIONAL","Stroke survivors frequently suffer disabilities including motor and cognitive problems, impairments in speech and vision, depression, and several other disabilities that worsen their quality of life. Some will recover fully after stroke and others will have permanent impairments. Few studies show trajectories of recovery in different domains after stroke, hence recovery time-lines are not fully known. Also, the whole range of mechanisms leading to recovery are not precisely known (1). To monitor those mechanisms one can utilize biomarkers.\n\nIn parallel to the studies of recovery, studies on time series of biomarkers after stroke are limited (2). Hence, a crucial first step to increase knowledge on biomarkers of stroke recovery is to gain a better understanding of the time course of both stroke recovery and biomarker patterns. Biomarkers can later be used for outcome predictions after stroke.",[25,26,27,28,29],"Stroke","Stroke Hemorrhagic","Stroke, Ischemic","Risk Factor, Cardiovascular","Cognitive Impairment",[31,32,33,34,35,36,37,38,39],"recovery","rehabilitation","stroke severity","plasticity","modified Rankin Scale","National Institutes of Health Stroke Scale","Fugl-Meyer assessment","blood sampling","stroke subtype","RECRUITING","2025-03-27",{"date":43,"type":44},"2025-04-02","ACTUAL",{"date":46,"type":44},"2018-02-01",{"date":48,"type":21},"2030-12-31",{"name":50,"class":51},"Göteborg University","OTHER",1,{"id":54,"slug":55,"hasResults":11,"nctId":56,"briefTitle":57,"officialTitle":58,"acronym":59,"eligibilityCriteria":60,"healthyVolunteers":61,"sex":17,"minAge":18,"maxAge":62,"enrollmentInfo":63,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":65,"conditions":66,"keywords":77,"overallStatus":84,"whyStopped":4,"lastUpdateSubmitDate":85,"lastUpdatePostDateStruct":86,"startDateStruct":88,"completionDateStruct":90,"leadSponsor":92,"locationsCount":4},"100543413","individual-factors-related-to-chronic-low-grade-inflammation-and-cardiometabolic-disease-risk-100543413","NCT06355544","Individual Factors Related to Chronic Low-grade Inflammation and Cardiometabolic Disease Risk","Integrative and Personalized Lifestyle Approach to Reduce Low-Grade Inflammation in People at Risk of Cardiometabolic Diseases","PINEAPPL","Inclusion Criteria:\n\n* Male or female between the ages of 18 and 70 included,\n* One of the following two criteria:\n* Clinically at-risk group Body Mass Index between 25 (included) and up to 35 kg\u002Fm2 (excluded)\n* Non-clinically at-risk group Body Mass Index between 18.5 (included) and up to 25 kg\u002Fm2 (excluded) and absence of metabolic syndrome criteria\n* Subject covered by social security or a similar system.\n* Ability to use a mobile phone application on a daily basis (food intake).\n* Subject, after being informed of the contents of this study, fully understanding and accepting its purpose; and able to personally sign a written informed consent\n\nExclusion Criteria:\n\n* Subject with diagnosed inflammatory disease or infection-related inflammation (viral or bacterial) or medical history (viral) within the last 2 months:\n* Rheumatoid arthritis, reactive or psoriatic arthritis (non-osteoarthritis)\n* Inflammatory bowel disease (IBD) (Crohn\\'s disease or ulcerative colitis) or irritable bowel syndrome\n* Systemic lupus erythematosus\n* Uncontrolled psoriasis\n* Viral hepatitis or ongoing viral infection\n* Seasonal virus (influenza-like illness)\n* Subjects who have taken antibiotics in the last 2 months\n* Subject under treatment within the last 2 months of an:\n* Antiviral (for HIV, hepatitis, influenza, chickenpox\u002Fshingles)\n* Oral, topical, or injectable treatment of a drug that modulates the inflammatory response (e.g. Corticosteroid, non-steroidal anti-inflammatory drugs (e.g. ibuprofen, diclofenac, celecoxib, naproxen, aspirin, etc.)\n* Dietary supplement that can modulate the inflammatory response (e.g.\n* Omega 3 fatty acid, curcuma\u002Fturmeric, probiotic, prebiotics)\n* Subject with diabetes (type 1 or 2) known treated prior to the inclusion visit (specifically subjects recently diagnosed or diagnosed with diabetes at the time of the laboratory assessment may be retained in the study if they are not taking anti-diabetic treatment): i.e. exclusion of subject with diabetes diagnosed with fasting blood glucose ≥ 126 mg\u002FdL (7.0 mmol measured twice\u002FL OR glycated hemoglobin ≥ 6.5% (48 mmol\u002Fmol) AND anti-diabetic therapy (metformin, GLP-1 receptor agonist, insulin, sulphonylurea, alpha-glucosidase inhibitor)\n* Subject with severe or unstable hepatic, renal, cardiovascular, respiratory, endocrine, or metabolic disorders or cancer diagnosed with or without treatment\n* Subject suffering from gastrointestinal disorders resulting in the use of laxatives or drugs for intestinal transit (e.g., loperamide) in the last 2 months.\n* Subject with a complication or procedure in the last 2 months that could result in inflammation\n* Minor or acute tendonitis, sprain, or contusion\n* Severe contusion (e.g. Bone contusion)\n* Major or invasive surgery\n* Subject in a situation that, in the opinion of the investigator, could interfere with optimal participation in the present study or pose a particular risk to the subject.\n* Subject currently participating in an interventional clinical study\n* Subject not affiliated to the Social Security scheme\n* Subject who did not comply with the exclusion period of the study in which they would have previously participated\n* Subject not being able to use the internet",true,"70 Years",{"count":64,"type":21},3000,"The goal of this observational study is to learn about low-grade inflammation in healthy individuals and individuals with overweight or obesity.\n\nThe main questions it aims to answer are:\n\n* Whether it is possible to predict low-grade inflammation\n* What are the medical, biological, and lifestyle variables related to low-grade inflammation?\n\nParticipants will be asked to:\n\n1. Attend a general medical visit to collect vital signs, anthropometric measurements, and collect blood samples.\n2. Complete questionnaires and collect a stool sample at home.",[67,68,69,70,71,72,28,73,74,75,76],"Overweight","Obesity","Metabolic Syndrome","Healthy","Low-grade Inflammation","Normal Weight Adults","Hypertension","Hypercholesterolemia","Abdominal Obesity","Metabolically Healthy Controls",[78,79,80,81,82,83],"nutrition","microbiome","lifestyle factors","low-grade inflammation","personalized nutrition","precision nutrition","NOT_YET_RECRUITING","2024-04-04",{"date":87,"type":44},"2024-04-09",{"date":89,"type":21},"2024-04",{"date":91,"type":21},"2026-06-30",{"name":93,"class":94},"Integrative Phenomics","INDUSTRY",{"id":96,"slug":97,"hasResults":11,"nctId":98,"briefTitle":99,"officialTitle":99,"acronym":100,"eligibilityCriteria":101,"healthyVolunteers":11,"sex":17,"minAge":102,"maxAge":62,"enrollmentInfo":103,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":105,"conditions":106,"keywords":115,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":117,"lastUpdatePostDateStruct":118,"startDateStruct":120,"completionDateStruct":122,"leadSponsor":123,"locationsCount":125},"100303086","prospective-urban-rural-epidemiology-study-100303086","NCT03225586","Prospective Urban Rural Epidemiology Study","PURE","Inclusion Criteria:\n\n* consenting adults between 35-70 years of age\n\nExclusion Criteria:\n\n* none","35 Years",{"count":104,"type":21},200000,"To examine the impact of health determinants at the individual (e.g. health related behaviors) and societal level (e.g. environmental factors, health related policy, quality of health systems) on health outcomes (e.g. death, non-communicable disease development) across a range of socioeconomic and health resource settings. Additional components of this study will examine genetic factors for non-communicable diseases. This will be examined both through a cross sectional component, and prospectively (cohort component).",[107,28,108,109,110,111,112,113,114],"Cardiovascular Diseases","Health Behavior","Environmental Exposure","Lung Diseases","Cancer","Injuries","Renal Disease","Communicable Disease",[116],"Non-communicable Diseases, Risk Factors","2024-01-29",{"date":119,"type":44},"2024-01-31",{"date":121,"type":44},"2002-01-01",{"date":48,"type":21},{"name":124,"class":51},"Population Health Research Institute",34,{"id":127,"slug":128,"hasResults":11,"nctId":129,"briefTitle":130,"officialTitle":131,"acronym":132,"eligibilityCriteria":133,"healthyVolunteers":61,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":134,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":135,"conditions":136,"keywords":4,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":137,"lastUpdatePostDateStruct":138,"startDateStruct":140,"completionDateStruct":142,"leadSponsor":144,"locationsCount":52},"100290796","it-is-a-prospective-study-aiming-to-identify-incidence-and-prevalence-of-cardiovascular-diseases-changes-in-physical-activity-dietary-habits-and-anxiety-depression-levels-through-a-period-of-time-in-the-naval-personnel-prospective-hellenic-naval-personnel-study-in-cardiovascular-diseases-100290796","NCT03065413","It is a Prospective Study Aiming to Identify Incidence and Prevalence of Cardiovascular Diseases, Changes in Physical Activity, Dietary Habits and Anxiety Depression Levels Through a Period of Time in the Naval Personnel (PrOspeCtive HEllenic NAval PersoNnel StUdy in CardiovaScular Diseases)","The PrOspeCtive HEllenic NAval PersoNnel StUdy in CardiovaScular Diseases (OCEANUS Study)","OCEANUS","Inclusion Criteria:\n\n\\-\n\nExclusion Criteria:\n\n* Non signed consent form",{"count":64,"type":21},"Prospective study. Starting from 2014 all newly appointed 1st year cadets in Naval Academies will be enrolled until the class of 2025.\n\nPhysical examination, food frequency questionnaire, physical activity questionnaire, anxiety\u002Fdepression questionnaire, medical history will be filled out at first interview.\n\nSpecific blood tests will be performed. Every participant will be interviewed every three years and will complete the same questionnaires.\n\nFollow up period is determined ten years after last class enrollment",[107,28],"2017-02-22",{"date":139,"type":44},"2017-02-27",{"date":141,"type":44},"2014-10",{"date":143,"type":21},"2035-12",{"name":145,"class":51},"Naval Hospital, Athens",{"id":147,"slug":148,"hasResults":11,"nctId":149,"briefTitle":150,"officialTitle":150,"acronym":151,"eligibilityCriteria":152,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":153,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":155,"conditions":156,"keywords":158,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":163,"lastUpdatePostDateStruct":164,"startDateStruct":166,"completionDateStruct":168,"leadSponsor":170,"locationsCount":52},"100285680","risk-evaluation-and-management-in-heart-failure-100285680","NCT02998788","Risk Evaluation and Management in Heart Failure","REM-HF","Inclusion Criteria:\n\n* aged 18 and above\n* inpatient with one of the following clinical situations:\n\n  * congestive heart failure (pulmonary edema,pulmonary congestion or peripheral edema)\n  * cardiogenic shock\n  * Insufficient high output cardiac\n* with impaired cardiac function diagnosed by echocardiography\n* able to provide informed consent\n\nExclusion Criteria:\n\n* expressed refusal to participate in the baseline investigation or follow-up visits Severe co-morbidity associated with a reduction in life expectancy of less than 12 months",{"count":154,"type":21},1000,"This is an prospective study conducted in a Chinese heart failure population. The study investigates the effects of cardiovascular disease risk factors such as lifestyle behaviors,biomarkers and intermediate diseases on heart failure prognosis.",[157,28],"Heart Failure",[159,160,161,162],"heart failure","risk factor","cardiovascular disease","lifestyle behavior","2016-12-19",{"date":165,"type":21},"2016-12-20",{"date":167,"type":4},"2016-06",{"date":169,"type":21},"2026-12",{"name":171,"class":51},"Ruijin Hospital"]