[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"risk-of-falling\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:risk-of-falling":30},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,44],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":4,"briefSummary":24,"conditions":25,"keywords":4,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":33,"lastUpdatePostDateStruct":34,"startDateStruct":37,"completionDateStruct":39,"leadSponsor":41,"locationsCount":4},"100642517","balance-fall-risk-and-gait-in-women-with-total-knee-arthroplasty-100642517",false,"NCT07650175","Balance, Fall Risk, and Gait in Women With Total Knee Arthroplasty","Investigation of Balance, Fall Risk, Gait Performance, and Quality of Life in Postmenopausal Women Undergoing Total Knee Arthroplasty","Inclusion Criteria:\n\n* Volunteering to participate in the study.\n* Being 60 years of age or older.\n* Having a Mini Mental Test score of 24 or higher.\n* Not having undergone previous arthroplasty surgery on the knee where surgery is planned.\n* Having experienced unilateral TDA.\n* Being a postmenopausal woman\n\nExclusion Criteria:\n\n* Individuals whose vital signs are unstable after surgery, or who develop any major complications such as deep vein thrombosis, pulmonary embolism, wound infection, or prolonged anesthesia side effects.\n* Presence of any neurological, vestibular, visual, cardiopulmonary, auditory, or cognitive deficits that may affect measurements.\n* Individuals diagnosed with diabetes.",true,"FEMALE","60 Years","85 Years",{"count":21,"type":22},30,"ESTIMATED","OBSERVATIONAL","Total knee arthroplasty (TKA) is a commonly performed surgical procedure aimed at reducing pain, restoring joint function, and improving quality of life, particularly among older women. Despite improvements in pain and functional outcomes following TKA, findings regarding balance, fall risk, and gait performance remain inconsistent. Impairments in these parameters may adversely affect daily activities, independence, and overall quality of life.\n\nUnlike previous studies that have primarily focused on one or two outcomes, this study will comprehensively evaluate balance, fall risk, gait performance, and quality of life in postmenopausal women who have undergone TKA. The findings are expected to provide a more holistic understanding of long-term functional outcomes following TKA and contribute to the planning of rehabilitation programs. Therefore, the aim of this study is to compare balance, fall risk, gait performance, and quality of life between postmenopausal women who have undergone TKA and healthy postmenopausal women.",[26,27,28,29,30,31],"Total Knee Arthroplasty","Postmenopausal Women","Quality of Life (QOL)","Balance","Risk of Falling","Walking","NOT_YET_RECRUITING","2026-06-10",{"date":35,"type":36},"2026-06-16","ACTUAL",{"date":38,"type":22},"2026-06-20",{"date":40,"type":22},"2026-07-22",{"name":42,"class":43},"Karabuk University","OTHER",{"id":45,"slug":46,"hasResults":11,"nctId":47,"briefTitle":48,"officialTitle":49,"acronym":50,"eligibilityCriteria":51,"healthyVolunteers":11,"sex":52,"minAge":53,"maxAge":4,"enrollmentInfo":54,"targetDuration":4,"studyType":56,"phases":57,"briefSummary":59,"conditions":60,"keywords":63,"overallStatus":66,"whyStopped":4,"lastUpdateSubmitDate":67,"lastUpdatePostDateStruct":68,"startDateStruct":70,"completionDateStruct":72,"leadSponsor":74,"locationsCount":76},"100585929","risk-of-falling-and-cardiac-rehabilitation-100585929","NCT06908759","Risk of Falling and Cardiac Rehabilitation","Risk of Falling Assessment in a Population of Patients With Cardiovascular Diseases Undergoing Cardiac Rehabilitation","CARDIO-BALANCE","Inclusion Criteria:\n\n\\- Age \\> 65 years\n\nRecent acute cardiac event, including:\n\n1. Cardiac surgery (CABG, aortic and\u002For mitral valve replacement, mitral valvuloplasty, or combined CABG + valve surgery)\n2. Recent myocardial infarction treated with percutaneous revascularization\n3. Episode of acute heart failure\n\nExclusion Criteria:\n\nPersistent clinical instability, defined as:\n\n* Marked hypotension (BP ≤ 95\u002F60 mmHg) or hypertension (BP ≥ 160\u002F100 mmHg)\n* Bradycardia (HR \\\u003C 50 bpm) or tachycardia (HR \\> 115 bpm)\n* Resting dyspnea\n* Signs and symptoms of infection","ALL","65 Years",{"count":55,"type":22},150,"INTERVENTIONAL",[58],"NA","Background and Rationale Cardiac rehabilitation (CR) is a key intervention for patients with chronic heart disease or recent acute cardiovascular events. In elderly and frail patients, CR aims not only to improve functional capacity but also to maintain or recover independence in daily activities. Hospitalization following an acute event often leads to bed rest, which-even after just 2-3 days-can cause hypokinetic syndrome, characterized by loss of muscle tone, orthostatic hypotension, decreased mobility, and psychological decline, including depression. Moreover, immobility increases thrombotic risk and vascular complications.\n\nTo mitigate these effects, CR is initiated promptly after clinical stabilization and includes three phases:\n\n1. Phase I - In-hospital rehabilitation\n2. Phase II - Early outpatient rehabilitation\n3. Phase III - Long-term maintenance Elderly patients are particularly vulnerable to falls due to the combined effects of reduced muscle strength, orthostatic hypotension, cognitive decline, and pre-existing sarcopenia-often exacerbated by acute events and immobility. Approximately 60% of cardiac patients hospitalized for acute events present with moderate-to-high fall risk. Fall risk in this population is multifactorial, involving cardiovascular issues (e.g., arrhythmias, orthostatic hypotension), medication effects, and non-cardiac factors such as vision loss, balance impairment, neuromuscular conditions, and cognitive deficits.",[30,61,62],"Elderly (People Aged 65 or More)","Cardiovascular Diseases",[64,65],"risk of fall","cardiac rehabilitation","RECRUITING","2025-04-02",{"date":69,"type":36},"2025-04-03",{"date":71,"type":36},"2024-05-31",{"date":73,"type":22},"2025-06-30",{"name":75,"class":43},"IRCCS San Raffaele Roma",1]