[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"robotic-assisted-laparoscopic-radical-prostatectomy\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:robotic-assisted-laparoscopic-radical-prostatectomy":75},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,47],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":32,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":36,"lastUpdatePostDateStruct":37,"startDateStruct":40,"completionDateStruct":42,"leadSponsor":44,"locationsCount":5},"100625777","phase-3-robotic-opioid-free-prostatectomy-enhanced-strategy-ropes-100625777",false,"NCT07427043","Robotic Opioid-free Prostatectomy Enhanced Strategy (ROPES)","Robotic Opioid-free Prostatectomy Enhanced Strategy (ROPES): Implementation of an Opioid-free Multimodal Analgesia Discharge Pathway","ROPES","Inclusion Criteria:\n\n* Men ≥45 years old\n* Undergoing Robotic Assisted Laparoscopic Prostatectomy (RALP) at BWH or BWFH\n* Able to provide informed consent\n\nExclusion Criteria:\n\n* Chronic kidney disease (baseline Cr \\>1.3)\n* NSAID contraindication\u002Fallergy\n* Regular opioid use or substance abuse prior to surgery\n* Inability to provide their own consent\n* Deviation from standard surgical practice for RALP (e.g. major complication requiring operative intervention that would result in patient no longer being considered a routine case)","MALE","45 Years",{"count":20,"type":21},300,"ESTIMATED","INTERVENTIONAL",[24],"PHASE3","This prospective, interventional, open-label, phase 3 randomized study evaluates a multimodal analgesia discharge pathway to reduce automatic opioid prescribing following routine robotic-assisted laparoscopic prostatectomy (RALP). Patients are counseled on post-operative pain management and then may opt into or out of the study with randomization to discharge prescriptions including (A) multimodal plan with additional automatic opioid prescription or (B) multimodal plan alone and instruction to call phone line to request opioid prescription if pain management is insufficient. Additionally, a cohort of historical controls prior to implementation of the study is also prospectively assessed as a pre-study baseline. The primary outcome is postoperative opioid consumption. Secondary outcomes include bowel function recovery, unplanned care encounters including emergency department visits or postoperative phone calls, and same-day discharge rates.",[27,28,29,30,31],"Opioid Consumption, Postoperative","Multimodal Analgesia","Robotic Assisted Laparoscopic Surgery","Robotic Assisted Laparoscopic Radical Prostatectomy","Prostate Cancer",[28,30,33,34,29],"Postoperative Opioid Consumption","Localized Prostate Cancer","RECRUITING","2026-05-20",{"date":38,"type":39},"2026-05-22","ACTUAL",{"date":41,"type":39},"2026-03-01",{"date":43,"type":21},"2027-04-30",{"name":45,"class":46},"Brigham and Women's Hospital","OTHER",{"id":48,"slug":49,"hasResults":11,"nctId":50,"briefTitle":51,"officialTitle":52,"acronym":4,"eligibilityCriteria":53,"healthyVolunteers":54,"sex":17,"minAge":55,"maxAge":56,"enrollmentInfo":57,"targetDuration":4,"studyType":59,"phases":4,"briefSummary":60,"conditions":61,"keywords":4,"overallStatus":64,"whyStopped":4,"lastUpdateSubmitDate":65,"lastUpdatePostDateStruct":66,"startDateStruct":68,"completionDateStruct":70,"leadSponsor":72,"locationsCount":74},"100582899","the-effect-of-steep-trendelenburg-position-on-neurocognitive-functions-in-robotic-radical-prostatectomy-cases-100582899","NCT06869304","The Effect of Steep Trendelenburg Position on Neurocognitive Functions in Robotic Radical Prostatectomy Cases","Examining the Effect of Steep Trendelenburg Position on Neurocognitive Functions With MoCA Test in Robotic-assisted Radical Prostatectomy Surgeries.","Inclusion Criteria:\n\n* Age ≥ 65 years\n* ASA II-III risk score\n* Patients scheduled for robotic radical prostatectomy\n* Patients who voluntarily agree to participate\n\nExclusion Criteria:\n\n* Age \\\u003C 65 years\n* History of neurological or psychiatric disorders\n* Inability to undergo robotic surgery\n* Conversion to open prostatectomy during surgery\n* Patients who do not consent to participate",true,"65 Years","100 Years",{"count":58,"type":21},56,"OBSERVATIONAL","The aim of this study is to evaluate the effects of the steep Trendelenburg position in robotic prostatectomy cases, where anesthesia depth is monitored using BIS and cerebral perfusion is tracked with NIRS, and to determine the incidence of neurocognitive dysfunction using the MoCA test in the postoperative period.\n\nSteep Trendelenburg position and CO₂ pneumoperitoneum during robotic radical prostatectomy lead to significant changes in intracranial pressure and cerebral oxygenation, which may contribute to postoperative neurocognitive dysfunction (POCD). Monitoring anesthesia depth with Bispectral Index (BIS) and cerebral perfusion with Near-Infrared Spectroscopy (NIRS) may help detect early neurocognitive changes, and MoCA test assessments will reveal a measurable decline in cognitive function postoperatively.",[62,30,63],"Neurocognitive Disorder","Near Infrared Spectroscopy","NOT_YET_RECRUITING","2025-03-10",{"date":67,"type":39},"2025-03-11",{"date":69,"type":21},"2025-03-15",{"date":71,"type":21},"2025-10-30",{"name":73,"class":46},"Ankara City Hospital Bilkent",1,"Robotic-assisted Laparoscopic Radical Prostatectomy"]