[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"rotator-cuff-repair\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:rotator-cuff-repair":33},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,4,0,[8,52,84,106],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":17,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":4,"briefSummary":22,"conditions":23,"keywords":34,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":40,"lastUpdatePostDateStruct":41,"startDateStruct":44,"completionDateStruct":46,"leadSponsor":48,"locationsCount":51},"100378588","evaluating-hemidiaphragmatic-paralysis-with-prolonged-neural-blockade-from-an-interscalene-brachial-plexus-block-100378588",false,"NCT04209504","Evaluating Hemidiaphragmatic Paralysis With Prolonged Neural Blockade From an Interscalene Brachial Plexus Block","Inclusion Criteria:\n\n* English speaking 18-80 year old ASA 1-3 patients\n* Primary shoulder surgery\n* Must live within a 25 mile radius\n\nExclusion Criteria:\n\n* ASA 4 or 5\n* Revision shoulder surgery\n* Diagnosis of chronic pain\n* Daily chronic opioid use (over 3 months of continuous opioid use)\n* Inability to communicate pain scores or need for analgesia\n* Infection at the site of block placement\n* Age under 18 years old or greater than 80 years old\n* Pregnant women (as determined by point-of-care serum bHCG)\n* Intolerance\u002Fallergy to local anesthetics\n* Weight \\\u003C50 kg\n* BMI \\> 40\n* severe pulmonary disease including chronic obstructive pulmonary disease and restrictive lung disease\n* Suspected, or known addiction to or abuse of illicit drug(s), prescription medicine(s), or alcohol within the past 2 years.\n* Uncontrolled anxiety, schizophrenia, or other psychiatric disorder that, in the opinion of the investigator, may interfere with study assessments or compliance.\n* Current or historical evidence of any clinically significant disease or condition that, in the opinion of the investigator, may increase the risk of surgery or complicate the subject's postoperative course.","ALL","18 Years","80 Years",{"count":19,"type":20},60,"ESTIMATED","OBSERVATIONAL","This prospective observational study aims to evaluate the incidence of hemidiaphragmatic paralysis in patients receiving interscalene brachial plexus nerve block with prolonged neural blockade. English speaking American Society of Anesthesiologists (ASA) 1-3 patients ages 18-80 receiving prolonged interscalene nerve block will be randomized into 3 groups: first group receiving a perineural catheter infusing 0.2% ropivacaine; the second group receiving a single shot injection of 10mL liposomal bupivacaine (Exparel; n=20) plus 5 mL 0.5% bupivacaine and the third receiving 20mL liposomal bupivacaine plus 5mL bupivacaine (to be determined by the attending anesthesiologist).Primary outcome will be incidence of hemidiaphragmatic paralysis postoperative day 1 as measured by point of care (POCUS) ultrasound.",[24,25,26,27,28,29,30,31,32,33],"Shoulder Surgery","Shoulder Pain","Shoulder Injuries","Shoulder Arthritis","Shoulder Disease","Rotator Cuff Tears","Rotator Cuff Injuries","Rotator Cuff Arthropathy of Left Shoulder","Rotator Cuff Arthropathy of Right Shoulder","Rotator Cuff Repair",[33,24,35,36,37,38],"Hemidiaphragmatic paralysis","Interscalene Block","Interscalene Catheter","Interscalene Liposomal Bupivacaine","RECRUITING","2025-09-29",{"date":42,"type":43},"2025-10-01","ACTUAL",{"date":45,"type":43},"2021-10-12",{"date":47,"type":20},"2026-08-31",{"name":49,"class":50},"Duke University","OTHER",1,{"id":53,"slug":54,"hasResults":11,"nctId":55,"briefTitle":56,"officialTitle":57,"acronym":4,"eligibilityCriteria":58,"healthyVolunteers":11,"sex":15,"minAge":59,"maxAge":60,"enrollmentInfo":61,"targetDuration":4,"studyType":63,"phases":64,"briefSummary":66,"conditions":67,"keywords":70,"overallStatus":74,"whyStopped":4,"lastUpdateSubmitDate":75,"lastUpdatePostDateStruct":76,"startDateStruct":78,"completionDateStruct":80,"leadSponsor":82,"locationsCount":51},"100587109","blood-flow-restriction-exercise-induced-hypoalgesia-100587109","NCT06924112","Blood Flow Restriction Exercise-induced Hypoalgesia","Exercise-induced Hypoalgesia Following Blood Flow Restriction in Rotator Cuff Repair Rehabilitation: a Randomized Crossover Clinical Trial","Inclusion Criteria:\n\n* Age between 40-65 years.\n* Symptomatic degenerative rotator cuff tear diagnosed by magnetic resonance imaging.\n* Undergoing arthroscopic rotator cuff repair\n* Be able to read and understand Spanish.\n\nExclusion Criteria:\n\n* Massive irreparable RC tears, concomitant fracture, labral or nerve injury.\n* Suspicion of developing\u002Fdiagnosis a frozen shoulder.\n* Revision surgery after RC repair.\n* Previous corticosteroid injection (\\\u003C 1 year).\n* Recent surgery (\\\u003C 1 year) in the contralateral shoulder.\n* A history of deep venous thrombosis\u002Fpulmonary embolism.\n* Peripheral vascular disease, thrombophilia or clotting disorders.\n* Severe or uncontrolled hypertension, or any comorbid condition that prevents participants from complete the intervention.","40 Years","65 Years",{"count":62,"type":20},22,"INTERVENTIONAL",[65],"NA","The goal of this crossover randomized clinical trial is to compare the acute effect on exercise-induced hypoalgesia (EIH) between isometric exercise with blood flow restriction (BFR) and isometric exercise alone in adults undergoing arthroscopic rotator cuff repair. It is presumed that the addition of BFR to isometric exercises induces a greater effect in EIH.\n\nPatients who agree to participate in this research will be randomly assigned to two intervention sequences (AB or BA), where intervention A (experimental) corresponds to isometric exercises with BFR, and intervention B (control) corresponds to isometric exercises alone. For one week, each participant attended two sessions, separated by a 72-hours wash-out period. The primary variables will be the pressure pain threshold (PPT) and conditioned pain modulation (CPM). Secondary variables will be the pain intensity and distribution, kinesiophobia, upper extremity disability, and quality of life. Results will be measured before intervention (T1, pre-intervention), immediate after intervention (T2, post-intervention 1) and 10 minutes after intervention (T3, post-intervention 2).",[68,69,33],"Rotator Cuff Injury","Rotator Cuff Tear",[71,72,73],"blood flow restriction therapy","blood flow restriction training","exercise-induced hypoalgesia","NOT_YET_RECRUITING","2025-04-04",{"date":77,"type":43},"2025-04-11",{"date":79,"type":20},"2025-05-01",{"date":81,"type":20},"2025-09-30",{"name":83,"class":50},"University of Valencia",{"id":85,"slug":86,"hasResults":11,"nctId":87,"briefTitle":88,"officialTitle":89,"acronym":90,"eligibilityCriteria":91,"healthyVolunteers":11,"sex":15,"minAge":59,"maxAge":60,"enrollmentInfo":92,"targetDuration":4,"studyType":63,"phases":94,"briefSummary":95,"conditions":96,"keywords":97,"overallStatus":74,"whyStopped":4,"lastUpdateSubmitDate":98,"lastUpdatePostDateStruct":99,"startDateStruct":101,"completionDateStruct":103,"leadSponsor":105,"locationsCount":51},"100576671","blood-flow-restriction-versus-standard-exercise-after-rotator-cuff-repair-100576671","NCT06788327","Blood Flow Restriction Versus Standard Exercise After Rotator Cuff Repair","Comparing the Effectiveness of Blood Flow Restriction Therapy Versus Standard Exercise After Arthroscopic Rotator Cuff Repair: Protocol for the Multicenter S-TRONGER Randomized Controlled Trial","S-TRONGER","Inclusion Criteria:\n\n* Age between 40-65 years\n* Symptomatic degenerative rotator cuff tear diagnosed by magnetic resonance imaging\n* Undergoing arthroscopic rotator cuff repair\n* Be able to read and understand Spanish\n\nExclusion Criteria:\n\n* Massive irreparable rotator cuff tear\n* Concomitant fracture\n* Labral or nerve injury\n* Suspicious of developing a frozen shoulder\n* Revision surgery after rotator cuff repair\n* Previous corticosteroid injection (\\\u003C 6 months)\n* Recent surgery (\\\u003C 1 year) in the contralateral shoulder\n* History of deep venous thrombosis\u002Fpulmonary embolism, peripheral vascular disease, thrombophilia or clotting disorders\n* Severe or uncontrolled hypertension, or any comorbid condition that impedes participants to complete the intervention",{"count":93,"type":20},50,[65],"The goal of this clinical trial is to determine the effectiveness of postoperative standard exercises with blood flow restriction therapy (BFRT) versus standard exercises alone on shoulder muscle strength and mass in participants with surgically treated rotator cuff tear. It is presumed that the addition of BFRT will significantly improve the shoulder strength and muscle mass at the end of the intervention period compared to the group receiving only standard exercises.\n\nPatients who agree to participate in this research will be randomly assigned to a control group (standard exercises alone) or an experimental group (standard rehabilitation with BFRT). The duration of the postoperative intervention will be 12 weeks. The primary variables will be the shoulder muscle strength and muscle mass. Secondary variables will be the active shoulder mobility, pain intensity, upper limb disability, and health-related quality of life. Results will be measured at 0, 4 and 12 weeks postoperative.",[68,29,33],[71,72],"2025-01-16",{"date":100,"type":43},"2025-01-23",{"date":102,"type":20},"2025-03-03",{"date":104,"type":20},"2027-08-31",{"name":83,"class":50},{"id":107,"slug":108,"hasResults":11,"nctId":109,"briefTitle":110,"officialTitle":111,"acronym":112,"eligibilityCriteria":113,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":4,"enrollmentInfo":114,"targetDuration":4,"studyType":63,"phases":116,"briefSummary":117,"conditions":118,"keywords":119,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":122,"lastUpdatePostDateStruct":123,"startDateStruct":125,"completionDateStruct":127,"leadSponsor":129,"locationsCount":131},"100535911","unexpected-positive-cultures-in-rotator-cuff-revision-surgery-100535911","NCT06257979","Unexpected Positive Cultures in Rotator Cuff Revision Surgery","Unexpected Positive Cultures in Rotator Cuff Revision Surgery: Significance and Influence on Outcomes and Tendon Healing","POCICO","Inclusion Criteria:\n\n* Patient, male or female, aged 18 or over\n* Patient requiring re- intervention for Rotator Ruff Revision Surgery for non-healing of the same tendons after a first intervention (delay \\\u003C2 years)\n* Patient requiring arthroscopy\n* Patient having had realized a MRI of the shoulder in the 6 previous months\n* Affiliate participant or beneficiary of a social security scheme\n* Participant having been informed and not having objected to the use of their data\n\nExclusion Criteria:\n\n* Patient with at least one clinical sign of infection (fever, redness)\n* Patient with a new distant rupture on a healed cuff (\\> 3 years)\n* Patient with a history of shoulder surgery other than initial Rotator Ruff Surgery\n* Patient having received antibiotic treatment in the 2 weeks preceding inclusion\n* Participant in another research\n* Participant in a period of exclusion from another research still in progress at the time of inclusion\n* Protected participant: an adult under guardianship, curatorship or other legal protection, deprived of liberty by judicial or administrative decision\n* Pregnant, breastfeeding or parturient woman\n* Participant hospitalized without consent",{"count":115,"type":20},132,[65],"In the context of rotator cuff re-intervention, the impact of Unexpected Positive Cultures (UPC) is not documented, and their management has not been studied, particularly regarding indications for antibiotic therapy, which is currently not a consensus.\n\nA prospective interventional study will be implemented to compare the results of non-randomized patient samples, whether positive or negative, taken during rotator cuff re-intervention. The objective is to assess whether these samples do not affect clinical outcomes and tendon healing rates.",[33],[120,121],"Unexpected Positive Cultures (UPC)","Revision cuff repair surgery (RCR)","2024-06-17",{"date":124,"type":43},"2024-06-18",{"date":126,"type":43},"2024-02-27",{"date":128,"type":20},"2028-03-15",{"name":130,"class":50},"Elsan",8]