[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"rotator-cuff-tendinitis\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:rotator-cuff-tendinitis":30},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,51,76],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":34,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":39,"lastUpdatePostDateStruct":40,"startDateStruct":43,"completionDateStruct":45,"leadSponsor":47,"locationsCount":50},"100523389","embolization-treatment-of-chronic-refractory-shoulder-tendinopathy-100523389",false,"NCT06095050","Embolization Treatment of Chronic Refractory Shoulder Tendinopathy","Efficacy of Lipiodol Embolization for Chronic Tendinopathy of the Rotator Cuff","ELECTRC","Inclusion Criteria:\n\n1. Male, female, transgender female, transgender male, non-binary\n2. Moderate to severe shoulder pain (VAS \\> 40)\n3. Pain refractory to at least 6 months of physician-directed conservative therapy (analgesics or injections or PT), including a minimum of 6 weeks of PT\n4. Willing, able, and mentally competent to provide informed consent and to tolerate angiography and physical therapy\n\nExclusion Criteria:\n\n1. History of peripheral arterial disease or peripheral artery disease symptoms including claudication, diminished or absent upper\u002Flower extremity pulses, or known upper extremity arterial atherosclerosis or occlusion that would limit selective angiography\n2. Known history of anaphylaxis to iodinated contrast agents or gadolinium based contrast\n3. Acute kidney injury\n4. Allergy to poppy seeds or lipiodol\n5. Renal dysfunction as defined by serum creatinine \\>1.6 dl\u002Fmg or eGFR \\\u003C60 obtained within 30 days of procedure.\n6. Uncorrectable coagulopathy (platelet count \\\u003C 50,000, international normalized ratio \\>1.8 within 30 days of procedure\n7. Active systemic or local upper extremity infection\n8. Patient pregnant, intending to become pregnant during the study.\n9. Prior shoulder replacement surgery\n10. Prior rotator cuff repair surgery\n11. Previous history of complete full-thickness tear of the rotator cuff\n12. Presence of non-MRI compatible devices (e.g., non-compatible cardiac pacemaker).","ALL","21 Years","80 Years",{"count":21,"type":22},41,"ESTIMATED","INTERVENTIONAL",[25],"NA","This is a randomized controlled trial in which patients with moderate to severe shoulder pain (Visual Analog Scale (VAS) \\> 40), in the setting of rotator cuff tendinopathy refractory to conservative treatment, will be enrolled.\n\nThe primary aim of the study is to estimate the effect of transcatheter arterial embolization (TAE) with physical therapy (PT) vs PT alone on the change in shoulder pain at 12-month follow up. Scientific objectives also include an assessment of safety of the intervention, assessment of changes in Patient-Reported Outcomes Measurement Information System (PROMIS) Upper Extremity score, Shoulder Pain and Disability Index (SPADI) scores, MRI Tendinopathy Score between the TAE + PT and PT groups.",[28,29,30,31,32,33],"Shoulder Pain","Tendinopathy","Rotator Cuff Tendinitis","Rotator Cuff Tendinosis","Embolization","Arterial Occlusion",[35,36,37],"pain","shoulder pain","tendinopathy","RECRUITING","2026-02-04",{"date":41,"type":42},"2026-02-06","ACTUAL",{"date":44,"type":42},"2025-01-16",{"date":46,"type":22},"2028-04-21",{"name":48,"class":49},"Brigham and Women's Hospital","OTHER",1,{"id":52,"slug":53,"hasResults":11,"nctId":54,"briefTitle":55,"officialTitle":56,"acronym":4,"eligibilityCriteria":57,"healthyVolunteers":11,"sex":17,"minAge":58,"maxAge":59,"enrollmentInfo":60,"targetDuration":4,"studyType":23,"phases":62,"briefSummary":63,"conditions":64,"keywords":4,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":67,"lastUpdatePostDateStruct":68,"startDateStruct":70,"completionDateStruct":72,"leadSponsor":74,"locationsCount":50},"100433388","therapeutic-exercise-for-rotator-cuff-tendinopathy--subacromial-pain-syndrome---outcomes-and-mechanisms-100433388","NCT04923477","Therapeutic Exercise for Rotator Cuff Tendinopathy \u002F Subacromial Pain Syndrome - Outcomes and Mechanisms","Mechanisms of Exercise for Rotator Cuff Tendinopathy \u002F Subacromial Pain Syndrome","Inclusion Criteria:\n\n1. the clinical diagnosis for RC tendinopathy will be made with positive 3 of 5 tests: Hawkins-Kennedy, Neer, painful arc, empty can, external rotation resistance test\n2. pain ≥ 3\u002F10 on a numeric pain rating scale\n3. age: 18 - 45 years\n4. Participant must read, sign and date the appropriate Informed consent document.\n5. Participant BMI ≤ 30\n\nExclusion Criteria:\n\n1. Insufficient ability to comprehend and complete the questionnaires,\n2. Inability to attend sessions,\n3. Prior surgery of shoulder, neck or thoracic spine,\n4. Primary complaint of neck or thoracic pain,\n5. Diagnosis of cervical spinal stenosis,\n6. Any serious spinal and shoulder pathology: infections, arthrosis, rheumatic disorders, acute fractures, shoulder dislocation, osteoporosis, or tumors,\n7. Central Nervous System involvement, to include hyperreflexia, sensory disturbances in the hand, intrinsic muscle wasting of the hands, unsteadiness during walking, nystagmus, loss of visual acuity, impaired sensation of the face, altered taste, the presence of pathological reflexes (i.e. positive Hoffman and\u002For Babinski reflexes,\n8. two or more neurologic signs of nerve root compression to include myotomal weakness, positive muscle stretch reflex, and dermatomal sensory loss,\n9. any shoulder or arm pain with cervical spine tests of Spurling's Test, cervical rotation to the ipsilateral side, or axial compression test, or\n10. primary adhesive capsulitis defined by passive range of motion loss \\>50% as compared bilaterally of shoulder external rotation, internal rotation, or elevation.\n11. Has a device or other condition that is not safe for MRI, including pacemakers.","18 Years","55 Years",{"count":61,"type":22},60,[25],"Rotator cuff tendinopathy, one of the pathologies identified as part of the cluster of shoulder symptoms known as subacromial pain syndrome, is a common musculoskeletal shoulder condition. Resolution of pain and disability is poor despite treatment, with only about 50% reporting full recovery at 12 - 18 months. Prior studies suggest therapeutic exercise when used alone and with other interventions can have positive outcomes; however, not all patients with rotator cuff tendinopathy respond. Few studies have assessed the effects of exercise for individuals with chronic pain, especially brain driven mechanisms, thought to play a key role. In this study, we will use brain imaging to understand the mechanisms, identify predictors of a positive response to exercise, and the relationship to biomechanical and pain-related factors in patients with RC tendinopathy. The findings from this study will optimize the delivery and treatment response to exercise for individuals with shoulder pain.",[31,30,65,66],"Rotator Cuff Injuries","Subacromial Pain Syndrome","2026-01-30",{"date":69,"type":42},"2026-02-03",{"date":71,"type":42},"2021-06-08",{"date":73,"type":22},"2026-12-31",{"name":75,"class":49},"University of Southern California",{"id":77,"slug":78,"hasResults":11,"nctId":79,"briefTitle":80,"officialTitle":81,"acronym":82,"eligibilityCriteria":83,"healthyVolunteers":11,"sex":17,"minAge":58,"maxAge":4,"enrollmentInfo":84,"targetDuration":4,"studyType":23,"phases":86,"briefSummary":87,"conditions":88,"keywords":4,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":90,"lastUpdatePostDateStruct":91,"startDateStruct":93,"completionDateStruct":95,"leadSponsor":97,"locationsCount":100},"100574488","performance-and-safety-of-lightforce-therapy-lasers-on-shoulder-soft-tissue-inflammation-pain-reduction-100574488","NCT06759935","Performance and Safety of LightForce® Therapy Lasers on Shoulder Soft Tissue Inflammation Pain Reduction","Randomized, Sham Controlled, Single Blind Study on the Performance and Safety of Photo Biomodulation Therapy (PBMT) With LightForce® Therapy Lasers on Shoulder Soft Tissue Inflammation Pain Reduction","SHINE","Inclusion Criteria:\n\n1. Patient male or female with age ≥18 years old\n2. Patient with diagnosis of shoulder soft tissue inflammation due to SAIS\u002FRCT (as confirmed by physical examination and\u002For imaging) to be treated by LightForce® Therapy Lasers according to its indications.\n3. Patient suffering from shoulder soft tissue inflammation due to SAIS\u002FRCT pain for more than 3 months prior to enrollment\n4. Pain (either persistent or during activities) score reported by the subject at baseline ≥ 40 mm measured on VAS\n5. Patient able to provide written informed consent\n\nExclusion Criteria:\n\n1. Patient with musculoskeletal pathological conditions not to be treated with\u002Fcontraindication to the use of LightForce® Therapy Lasers according to its intended use and indications\n2. Patients who are taking drugs that have heat or light sensitive contraindications, such as but not limited to certain types of steroids\n3. Patients who are administered with corticosteroids, should discontinue the treatment at least 2 weeks prior to study treatment start\n4. Pregnant females or females of childbearing potentially planning to become pregnant during the study participation\n5. Patients who had systemic inflammatory conditions (i.e.rheumatoid arthritis, polymyalgia rheumatica)\n6. Patients who underwent intra-articular injection (Ialuronic acid, platelet rich plasma or corticosteroids) in the shoulder in the last 3 months\n7. Patients who have a disease that would limit their participation in exercises (i.e. severe chronic obstructive pulmonary disease, severe heart failure, cerebrovascular event history)\n8. Patients with a prior history of surgical intervention and implantation of a metal implant into the affected shoulder\n9. Patients with a diagnosis of active cancer\n10. Patients with tattoos covering more than 30% of the area to be treated with LightForce® Therapy Lasers\n11. Patients who are mentally or physically incapacitated\n12. Patient participating in other clinical study or has completed a clinical study less than 30 days prior to enrollment\n13. Patient affected by shoulder soft tissue acute inflammation due to recent sport injury or trauma\n14. Patients with other musculoskeletal problems of the shoulder joint such as calcifying tendinitis, full thickness rotator-cuff tear, adhesive capsulitis, fibromyalgia, recent surgery or fracture of the shoulder joint, and\u002For undergoing to specific physiotherapy for these (\"recent\" is defined as within 30 days prior to enrollment).\n15. Patients with other clinically significant co-morbidities that make the patient unsuitable for study participation, at the discretion of the investigator",{"count":85,"type":22},130,[25],"DJO UK Ltd (ENOVIS) is conducting this study to assess the effectiveness of LightForce® Therapy Lasers on pain reduction in shoulder soft tissue inflammation. In detail this study will assess superiority of LightForce® Therapy Lasers combined with standard of care, represented by physiotherapy\u002Fexercise program compared to sham laser combined with standard of care (physiotherapy\u002Fexercise program) on pain reduction in subjects with shoulder soft tissue inflammation due to Impingement (Subacromial impingement syndrome (SAIS)) or Rotator Cuff Tendinopathy (RCT),. In addition, this study allows to collect post market clinical data on the safety and performance of LightForce® Therapy Lasers, when used, following the normal clinical practice, in accordance with its approved and CE marked intended use.",[28,89,30],"Shoulder Impingement Syndrome","2025-11-14",{"date":92,"type":42},"2025-11-17",{"date":94,"type":42},"2025-02-21",{"date":96,"type":22},"2026-12",{"name":98,"class":99},"DJO UK Ltd","INDUSTRY",10]