[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"rural-health\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:rural-health":31},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,12,0,[8,54,114,162,195,221,249,273,308,338,361,392],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":33,"overallStatus":41,"whyStopped":4,"lastUpdateSubmitDate":42,"lastUpdatePostDateStruct":43,"startDateStruct":46,"completionDateStruct":48,"leadSponsor":50,"locationsCount":53},"100609805","virtual-reality-lethal-means-safety-training-100609805",false,"NCT07219355","Virtual Reality Lethal Means Safety Training","Expanding Provider Capacity to Prevent Rural Veteran Suicide: Virtual Reality Lethal Means Safety Training","Inclusion Criteria:\n\n* Age 18 or older\n* healthcare providers serving rural Veterans in Texas (e.g., physicians, physician assistants, nurse practitioners, nurses, pharmacists, social workers, healthcare case managers)\n* English-speaking\n* Able to provide informed consent\n\nExclusion Criteria:\n\n* Self-reported pregnancy\n* History of motor or balance disorders\n* Color blindness\n* Neurological or cognitive disorders\n* Cardiovascular issues that may be worsened by VR use\n* Use of cardiac pacemakers, defibrillators, or hearing aids incompatible with VR equipment\n* Significant discomfort in virtual reality environments (e.g., severe motion sickness, vertigo)",true,"ALL","18 Years",{"count":20,"type":21},36,"ESTIMATED","INTERVENTIONAL",[24],"NA","The goal of this randomized clinical trial is to determine whether a virtual reality (VR) training program can help healthcare providers improve their skills in discussing suicide prevention and safe storage of firearms and medications with Veterans. The study will test whether VR training increases providers' self-efficacy, confidence, and comfort in conducting lethal means safety counseling, and whether it improves their intention to use these counseling practices in their clinical work. Researchers will compare healthcare providers who complete the VR training to those who complete a 2D video training to determine whether the VR approach is more effective. Participants will complete online surveys before and after the training and again three months later. They will be randomly assigned to one of two groups: VR training group: Participants use a VR headset to interact with a virtual Veteran patient in a simulated rural clinic and practice suicide prevention counseling skills; Video training group: Participants use the same headset to watch a \\~10-minute 2D video depicting the lethal means safety counseling session. After the training, participants will also provide feedback about their experience, including how realistic and useful they found the training.",[27,28,29,30,31,32],"Suicide, Attempted","Suicide, Completed","Suicide Prevention","Mental Health Training","Rural Health","Veterans",[32,34,29,35,36,37,38,39,40,31],"Rural Veterans","Suicide Risk","Firearm Safety","Medication Safety","Lethal Means Safety Counseling","Virtual Reality (VR)","VR Training Simulation","RECRUITING","2026-06-23",{"date":44,"type":45},"2026-06-24","ACTUAL",{"date":47,"type":45},"2026-02-23",{"date":49,"type":21},"2026-09-30",{"name":51,"class":52},"The University of Texas at Arlington","OTHER",1,{"id":55,"slug":56,"hasResults":11,"nctId":57,"briefTitle":58,"officialTitle":59,"acronym":60,"eligibilityCriteria":61,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":62,"targetDuration":4,"studyType":22,"phases":64,"briefSummary":65,"conditions":66,"keywords":81,"overallStatus":41,"whyStopped":4,"lastUpdateSubmitDate":104,"lastUpdatePostDateStruct":105,"startDateStruct":107,"completionDateStruct":109,"leadSponsor":111,"locationsCount":53},"100643981","health-ahead-comparative-effectiveness-study-100643981","NCT07669168","Health Ahead Comparative Effectiveness Study","Health Ahead: Sequential Comparative-Effectiveness Studies Toward Automated, Universally Deployable Preventive Health Screening","HACE","Inclusion Criteria:\n\n* Age 18 years or older\n* Willing and able to provide written informed consent, or enrollment with consent of a legally authorized representative\n* Willing to participate in longitudinal follow-up.\n\nExclusion Criteria:\n\n\\- Age under 18 years.",{"count":63,"type":21},1000000,[24],"The Health Ahead Comparative Effectiveness Study is a pragmatic, parallel-arm interventional platform that systematically compares successive changes to preventive health screening - each isolated as a single variable against current practice - on the path toward a fully automated screening system deployable in any environment, including the most isolated and resource-limited communities. Each comparison is evaluated with a common set of engagement, behavior-change, experience, cost, and longitudinal outcome measures, allowing results to accumulate on a consistent yardstick across the life of the platform.\n\nThe first comparison evaluates static versus interactive personalized health report delivery. Subsequent pre-planned comparisons, added by protocol amendment, evaluate mobile community versus fixed laboratory screening; and a hybrid medical-droid plus human-delivery model versus human-only screening. All participants are simultaneously enrolled in the 100-Year Human Aging Study and the Human Observatory Study, contributing individual longitudinal and population-level causal inference data through those protocols.",[67,31,68,69,70,71,72,73,74,75,76,77,78,79,80],"Health Services Accessibility","Medically Underserved Area","Preventive Health Services","Patient Participation","Health Behavior","Aging","Cardiovascular Diseases","Metabolic Syndrome","Cognitive Dysfunction","Frailty","Activities of Daily Living","Health Related Quality of Life","Health Equity","Telemedecine",[82,83,84,85,86,79,31,87,88,89,90,91,92,93,94,95,96,97,98,99,100,101,102,103],"Sequential Platform Trial","Interactive Health Report","Health Activation","Mobile Health Screening","Comparative Effectiveness","Medically Underserved","Preventive Medicine","Patient Engagement","Cardiopulmonary Exercise Testing","Body Composition","DEXA","Health Ahead Bus","Mobile Clinic","Automated Screening","Medical Droids","Biological Age","Healthspan","Longevity","Life Expectancy","Chronic Disease","Cost-Effectiveness","Health Services Research","2026-06-20",{"date":106,"type":45},"2026-06-25",{"date":108,"type":21},"2026-06-09",{"date":110,"type":21},"2099-12-31",{"name":112,"class":113},"William Brandenburg, MD","INDUSTRY",{"id":115,"slug":116,"hasResults":11,"nctId":117,"briefTitle":118,"officialTitle":119,"acronym":120,"eligibilityCriteria":121,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":122,"targetDuration":4,"studyType":124,"phases":4,"briefSummary":125,"conditions":126,"keywords":132,"overallStatus":41,"whyStopped":4,"lastUpdateSubmitDate":153,"lastUpdatePostDateStruct":154,"startDateStruct":156,"completionDateStruct":158,"leadSponsor":160,"locationsCount":53},"100614348","reducing-parental-substance-use-and-enhancing-family-resilience-among-rural-families-through-ohio-start-100614348","NCT07278427","Reducing Parental Substance Use and Enhancing Family Resilience Among Rural Families Through Ohio START","Reducing Parental Substance Use, Improving Child Health Outcomes, and Enhancing Family Resilience Among Rural Families Through Ohio START (Sobriety, Treatment, and Reducing Trauma)","Ohio START","Inclusion Criteria:\n\n* age 18 or older;\n* currently enrolled in Ohio START;\n* are unemployed or have family income at or below the federal poverty level,\n* designated as the primary parent in the Ohio START case plan.",{"count":123,"type":21},400,"OBSERVATIONAL","The goal of this observational study is to learn about the roles played by parental activity spaces and social networks in reducing parental substance use and promoting child and family health outcomes in the context of Ohio START (Sobriety, Treatment, and Reducing Trauma) for families in rural areas. This study will investigate if substance use treatment service referrals and family peer mentoring services provided by Ohio START lead to positive changes in parental activity spaces and social networks, and if these positive changes lead to better child and family outcomes. The main questions it aims to answer are:\n\n* Does having behavioral health services (referred by Ohio START workers) close to where parents spend their time help with substance use recovery and child health?\n* Does peer mentor support through Ohio START help parents build stronger social connections and family resilience, and does this lead to better long-term family health?\n* Do these associations differ in rural areas compared to urban areas?\n\nParticipants will:\n\n* Answer survey questions about their substance use, parenting, child health, and family well-being across three waves (Wave 1: when they enroll in the study, Wave 2: 6-month follow-up, and Wave 3: 12-month follow-up)\n* Share information about places they go regularly (such as work, stores, and healthcare visits)\n* Share information about people in their support network",[127,31,128,129,130,131],"Substance Use Disorder (SUD)","Family Resilience","Child Maltreatment","Child Well-beiing","Substance Use Recovery",[133,134,135,136,137,138,139,140,141,142,143,144,145,146,147,148,120,149,150,151,152],"Substance use disorder","Child abuse and neglect","Rural health","Child welfare services","Low socioeconomic status","Rurality","Longitudinal study","Prospective study","Family resilience","Social network","Activity spaces","Child maltreatment","Parental substance use","Family peer mentors","Social networks","Rural families","Child well-being","Substance use treatment services","Family health","The START model","2026-05-12",{"date":155,"type":45},"2026-05-14",{"date":157,"type":45},"2026-04-27",{"date":159,"type":21},"2030-08-31",{"name":161,"class":52},"Ohio State University",{"id":163,"slug":164,"hasResults":11,"nctId":165,"briefTitle":166,"officialTitle":167,"acronym":4,"eligibilityCriteria":168,"healthyVolunteers":16,"sex":17,"minAge":169,"maxAge":4,"enrollmentInfo":170,"targetDuration":4,"studyType":22,"phases":172,"briefSummary":173,"conditions":174,"keywords":179,"overallStatus":41,"whyStopped":4,"lastUpdateSubmitDate":186,"lastUpdatePostDateStruct":187,"startDateStruct":189,"completionDateStruct":191,"leadSponsor":193,"locationsCount":53},"100605285","healthy-children-healthy-communities-effectiveness-of-a-multilevel-rural-community-engagement-model-for-improving-childrens-dietary-intake-in-family-child-care-homes-100605285","NCT07160530","Healthy Children, Healthy Communities: Effectiveness of a Multilevel Rural Community Engagement Model for Improving Children's Dietary Intake in Family Child Care Homes","Cluster Randomized Controlled Trial of a Multilevel Rural Community Engagement Model for Improving Children's Dietary Intake in Family Child Care Homes","Inclusion Criteria:\n\nFCCH Settings:\n\n* Licensed family child care home-based early child care and education settings\n* Located in Nebraska (with potential expansion to Iowa, Kansas, South Dakota, Oklahoma, Illinois, and\u002For Northwest Missouri if needed)\n* Participate in the Child and Adult Care Food Program (CACFP)\n* Care for at least 2 preschool-aged non-sibling children (3-5 years old) without feeding disorders or developmental delays\n* Provide meals and snacks to attending children\n* Located in a county designated as nonmetropolitan based on the 2023 Rural-Urban Continuum Codes (RUCC)\n\nFCCH Providers:\n\n* Currently caring for at least two 3-5 year old non-sibling children who do not have dietary restrictions or feeding disorders that impact how they eat\n* Present with children during meals and snacks\n* Over the age of 19 years\n* Have not participated in this study before\n\nChildren:\n\n* Between 3 to 5 years old\n* No dietary restrictions or feeding disorder that impact how they eat (lactose intolerance, egg\u002Fnut allergies, or vegetarian diet are acceptable)\n* Typically developing children (no diagnosis of developmental delays as identified by childcare providers)\n* Have a parent or guardian 19 years of age or older to consent for them\n\nExclusion Criteria:\n\nFCCH Providers:\n\n* FCCH provider closes the business\n* FCCH provider stops serving meals to children\n* FCCH provider discontinues participation in CACFP and no longer adheres to CACFP meal pattern requirements\n* FCCH provider loses all eligible study children due to children leaving care, developing developmental delays or feeding disorders, or other reasons making them ineligible\n\nChildren:\n\n* Diagnosis of dietary restrictions or feeding disorder that impact how they eat (soft diet requirements or difficulty swallowing that impacts how they eat)\n* Diagnosis of developmental delays\n* A sibling of a participating child (only one 3-5 year old child per family eligible)","3 Years",{"count":171,"type":21},360,[24],"The purpose of this study is to find out whether a program called \"Healthy Children, Healthy Communities\" can help young children in rural areas eat healthier and improve their health. The study focuses on children ages 3 to 5 who attend family childcare homes in rural communities.\n\nThe main goal is to see if the program can:\n\nHelp children eat healthier foods, like more fruits and vegetables.\n\nSupport childcare providers in using positive mealtime practices that encourage healthy eating.\n\nThe study will involve about 120 licensed family childcare providers in rural areas who participate in the Child and Adult Care Food Program (CACFP), along with about 240 children they care for.\n\nChildcare providers will be randomly placed into one of two groups:\n\nEAT Family Style Group (Intervention Group):\n\nComplete 7 online training modules over 16 weeks about healthy mealtime practices.\n\nJoin 7 individual coaching sessions on Zoom.\n\nRecord short videos of their mealtimes to get personalized feedback from a coach.\n\nWork with a coach to set goals and make plans to improve mealtimes.\n\nReceive printed materials and conversation cards to use during meals.\n\nSome providers may join Zoom interviews to share their experiences.\n\nBetter Kid Care Group (Comparison Group):\n\nComplete 10 online modules about general childcare topics like child development, oral health, play, and managing a childcare home.\n\nFor both groups, the research team will:\n\nAsk providers to fill out online surveys about how mealtimes work in their childcare homes.\n\nVisit the childcare homes to observe and record children's mealtimes on two days at each data collection point.\n\nMeasure the height and weight of participating children.\n\nUse a painless skin scanner (Veggie Meter) to check how many fruits and vegetables children have been eating.\n\nAsk providers to complete surveys about the children's eating habits.\n\nThe study focuses on rural, low-income communities, where children are at higher risk of having poor diets and obesity compared to children in urban areas. Information will be collected at the start of the study, after 16 weeks, and again after 24 weeks to see if there are lasting changes.",[175,176,177,178,31],"Childhood Obesity Pevention","Diet Quality","Feeding Behaviors","Health Behavior Change",[180,181,182,183,184,185],"Rural population","Feeding Behavior","Child Care","Child Feeding","Carotenoids","Body Mass Index","2026-04-16",{"date":188,"type":45},"2026-04-20",{"date":190,"type":45},"2025-09-25",{"date":192,"type":21},"2029-05-31",{"name":194,"class":52},"University of Nebraska Lincoln",{"id":196,"slug":197,"hasResults":11,"nctId":198,"briefTitle":199,"officialTitle":200,"acronym":4,"eligibilityCriteria":201,"healthyVolunteers":11,"sex":17,"minAge":202,"maxAge":203,"enrollmentInfo":204,"targetDuration":4,"studyType":22,"phases":206,"briefSummary":207,"conditions":208,"keywords":4,"overallStatus":41,"whyStopped":4,"lastUpdateSubmitDate":211,"lastUpdatePostDateStruct":212,"startDateStruct":214,"completionDateStruct":216,"leadSponsor":218,"locationsCount":220},"100584336","iamhealthy-clinical-practice-guideline-cpg-100584336","NCT06888011","iAmHealthy Clinical Practice Guideline (CPG)","Implementation of the New Pediatric Obesity Clinical Practice Guideline in Rural Families and Clinics: A Randomized Clinical Trial","Inclusion criteria for individual participants:\n\n* Child is ages 6-11 years at consent\n* Child BMI %ile is ≥85th\n* Child lives in a rural area\n* Child\u002Ffamily speaks English or Spanish\n\nExclusion criteria for individual participants:\n\n* Child has a physical limitation or injury that substantially limits physical mobility or has a planned medical treatment during the course of the trial that will substantially limit physical mobility\n* Child has a known medical issue that could affect protocol compliance (e.g., cancer)\n* Child and\u002For primary caregiver has a developmental delay or cognitive impairment that could affect protocol compliance\n* Child is enrolled in a weight-loss trial\n* Child has a sibling who has already consented in the trial\n\nInclusion criteria for clinics:\n\n* History of collaboration with site awardee in research or quality improvement projects\n* In the past year at least 300 eligible potential participants\n* The clinic must have an electronic medical records system\n\nExclusion criteria for clinics:\n\n* Unable to generate lists of children seen in clinic by date of visit, age, and zip code","6 Years","11 Years",{"count":205,"type":21},1024,[24],"The current study is a multilevel factorial design RCT with interventions at the clinic (Healthy Clinic intervention period vs. Control period) and individual patient levels (iAmHealthy vs. Newsletter).",[209,31,210],"Pediatric Obesity","Clinical Practice Guideline","2026-04-07",{"date":213,"type":45},"2026-04-13",{"date":215,"type":45},"2025-09-02",{"date":217,"type":21},"2028-11",{"name":219,"class":52},"University of Kansas Medical Center",4,{"id":222,"slug":223,"hasResults":11,"nctId":224,"briefTitle":225,"officialTitle":226,"acronym":227,"eligibilityCriteria":228,"healthyVolunteers":16,"sex":17,"minAge":229,"maxAge":4,"enrollmentInfo":230,"targetDuration":4,"studyType":22,"phases":232,"briefSummary":233,"conditions":234,"keywords":237,"overallStatus":41,"whyStopped":4,"lastUpdateSubmitDate":240,"lastUpdatePostDateStruct":241,"startDateStruct":243,"completionDateStruct":245,"leadSponsor":247,"locationsCount":53},"100612523","the-food-for-health-study-100612523","NCT07254689","The Food for Health Study","A Produce Prescription Program Aimed at Reducing Food Insecurity and Type 2 Diabetes Risk Among Native American Older Adults","F4H","Inclusion Criteria:\n\n* Adults aged 55 years or older\n* Live on the Flathead Reservation\n* Self-identify as Native American (NA)\n* Food insecurity, as determined using Hunger Vital Sign™, a two question screener asked by providers.\n* Diabetes diagnosis\n* Pre-diabetic based on HbA1c lab results of (5.7-6.4%) or scores 5+ on the National Diabetes Prevention Programs screener based on health and history.\n\nExclusion Criteria:\n\n* Individuals with end-stage renal disease\n* Their health provider states they should not participate","55 Years",{"count":231,"type":21},43,[24],"The project, called Food for Health (F4H), will study a new Produce Prescription Program (PPP) designed for rural Native American older adults. The study is based in the Confederated Salish and Kootenai Tribes (CSKT) of the Flathead Indian Reservation in Montana. In this community, many older adults face food insecurity and higher risk for Type 2 Diabetes (T2D). The tribal health department (THD) and local Food Resource Center (FRC) already provide important health and food support services, and this project builds on these strengths.\n\nProduce Prescription Programs (PPPs) is a type of nutrition support intervention that connects healthcare providers with local food programs to help patients access fresh, healthy foods. For example, an individual enrolled in the study will be \"prescribe\" fruits and vegetables in the form of a vouchers or coupons, which can be used to buy these foods at local food centers. Research shows that this type of program can reduce food insecurity, improve diet, and support better health. PPPs also fit well with tribal community priorities by supporting food sovereignty, culture-based nutrition education, and a stronger local food system.\n\nA key part of the study approach is using Community-Based Participatory Research (CBPR). CBPR means that community members, health providers, and researchers work together as equal partners. This way, the program is not just designed \"for\" the community, but \"with\" the community. The CSKT THD and community members have been involved in shaping this project from the start, and their priorities-like food security and food sovereignty-are at the center of the work.\n\nThe investigators will carry out the study in two phases.\n\nPhase 1: Investigators will pilot test the acceptability of F4H in a small group of older adults (N=10) to understand the program's acceptability. The results will be used to refine and improve the program before moving to the next phase.\n\nPhase 2: Investigators will test the feasibility and impact of the refined F4H program with a larger group of older adults (N=33). Participant food insecurity and T2D risk factors, such as blood sugar and weight, will be measured before and after the program. Investigators expect that participants will have less food insecurity and healthier measures after completing the program.\n\nThe clinic-to-community model is central to F4H. The THD will provide the prescriptions, and the FRC will be where participants redeem vouchers for fruits, vegetables, and other nutritious foods. The program will also include nutrition education that is grounded in Native culture and values. This model helps strengthen connections between healthcare and community services, creating a more supportive system for older adults.\n\nIn addition to testing the program, investigators will study how it is carried out. This is called implementation research. It means paying attention to how the program fits into the community setting, what helps it succeed, and what barriers might need to be addressed. Understanding these factors is important so that the program can continue in the future and potentially be expanded to other Native communities.\n\nThe long-term goal of F4H is to empower Native American communities to improve nutrition and reduce health disparities. By supporting older adults in gaining better access to healthy foods, the aim is to lower diabetes risk, improve quality of life, and strengthen local food systems. If the program is successful, it can serve as a model for other rural communities facing similar challenges.",[235,236,31],"Type 2 Diabetes","Food Insecurity",[238,239],"produce prescription program","Native American","2026-04-02",{"date":242,"type":45},"2026-04-03",{"date":244,"type":45},"2026-04-01",{"date":246,"type":21},"2028-09-30",{"name":248,"class":52},"University of Montana",{"id":250,"slug":251,"hasResults":11,"nctId":252,"briefTitle":253,"officialTitle":254,"acronym":255,"eligibilityCriteria":256,"healthyVolunteers":11,"sex":17,"minAge":229,"maxAge":4,"enrollmentInfo":257,"targetDuration":4,"studyType":22,"phases":259,"briefSummary":260,"conditions":261,"keywords":4,"overallStatus":41,"whyStopped":4,"lastUpdateSubmitDate":264,"lastUpdatePostDateStruct":265,"startDateStruct":267,"completionDateStruct":269,"leadSponsor":271,"locationsCount":53},"100630548","forge-ahead-feasibility-of-yoga-to-improve-cognitive-function-100630548","NCT07489105","Forge AHEAD: Feasibility of Yoga to Improve Cognitive Function","Engaging Stakeholders and Patients to Evaluate the Feasibility of Yoga to Improve Cognitive Function in Rural Heart Failure Patients in the Deep South","Forge AHEAD","Inclusion Criteria:\n\n* Heart failure diagnosis\n* Aged 55 years or older\n\nExclusion Criteria:\n\n* Traumatic brain injury, co-existing neurological and psychiatric disorders\n* Implanted defibrillator or metal objects, left ventricular assist device placement, or cardiac transplant\n* Substance abuse\n* Unable to perform yoga due to physical limitations or severity of illness\n* Currently engaged in a yoga program",{"count":258,"type":21},20,[24],"The investigators will conduct a two-phase pilot study to test the feasibility and acceptability of a 12-week Chair Yoga intervention for 20 heart-failure patients. Using a patient-centered approach, investigators will involve stakeholders in designing the protocol, gather patient feedback, and refine the protocol accordingly.",[262,31,263],"Heart Failure","Engagement, Patient","2026-03-21",{"date":266,"type":45},"2026-03-25",{"date":268,"type":45},"2025-07-24",{"date":270,"type":21},"2027-12-31",{"name":272,"class":52},"Auburn University",{"id":274,"slug":275,"hasResults":11,"nctId":276,"briefTitle":277,"officialTitle":277,"acronym":278,"eligibilityCriteria":279,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":280,"targetDuration":4,"studyType":22,"phases":282,"briefSummary":283,"conditions":284,"keywords":290,"overallStatus":41,"whyStopped":4,"lastUpdateSubmitDate":299,"lastUpdatePostDateStruct":300,"startDateStruct":302,"completionDateStruct":304,"leadSponsor":306,"locationsCount":53},"100598506","nutritional-prehabilitation-to-improve-cancer-outcomes-n-pico-100598506","NCT07072377","Nutritional Prehabilitation to Improve Cancer Outcomes (N-PICO)","N-PICO","Inclusion Criteria:\n\n* Diagnosis of invasive cancer with plans to initiate chemo-, immune-, targeted-, or hormonal therapy for treatment of their malignancy, or within one month of starting treatment.\n* Age ≥ 18 years of age.\n* Patients must be able to read, write, and speak English as study material and virtual nutrition consultation calls are only available in English.\n* Patients receiving treatment at a participating ambulatory medical oncology site.\n* Willingness to have a remote nutritional consultation and complete questionnaires\u002Fsurveys.\n* Patients must be informed of the investigational nature of this study and must sign and give written informed consent in accordance with institutional and federal guidelines.\n\nExclusion Criteria:\n\n* Diagnosis of acute leukemia (these patients generally receive predominantly inpatient care).\n* Diagnosis of head \\& neck cancer, esophageal cancer, gastric cancer, patients presenting with recognized cachexia or severe malnutrition, or patients with PEG tubes for enteral feeding.\n\nRationale: These patients would normally be referred for dietary consultation and may need ongoing clinical intervention from an on-site dietitian beyond the period of the proposed study",{"count":281,"type":21},240,[24],"Brief Summary\n\nThe goal of this clinical trial is to evaluate the acceptability and adherence of low- and high-intensity remote nutritional interventions for cancer patients in rural and urban areas, specifically focusing on those with invasive cancer who are about to start treatment. The main question\\[s\\] it aims to answer are:\n\nCan low- and high-intensity remote nutritional interventions improve adherence to cancer treatment and quality of life? What is the impact of nutritional support on treatment delays, unplanned healthcare utilization, and dietary modifications? Researchers will compare the low-intensity arm (initial nutritional consultation plus written materials) to the high-intensity arm (1-hour consultation, monthly follow-ups, and written materials) to see if higher intensity interventions lead to better outcomes in terms of adherence, quality of life, and healthcare utilization.\n\nParticipants will:\n\nReceive either a low- or high-intensity nutritional consultation. Complete surveys assessing quality of life, dietary habits, treatment delays, and unplanned healthcare use.\n\nBe asked to participate in monthly follow-up consultations (for the high-intensity group) to track progress and provide additional support.",[285,286,287,288,289,31],"Malnutrition","Cancer-related Malnutrition","Quality of Life (QOL)","Nutritional Support","Nutritional Interventions",[291,292,293,294,295,296,297,298],"Cancer Nutrition Intervention","Malnutrition in Cancer Patients","Nutritional Support for Cancer","Prehabilitation Program for Cancer","Rural Cancer Nutrition","Quality of Life and Cancer Nutrition","Remote Nutritional Consultations","Cancer Treatment Outcomes and Nutrition","2026-02-02",{"date":301,"type":45},"2026-02-05",{"date":303,"type":45},"2025-09-10",{"date":305,"type":21},"2028-09",{"name":307,"class":52},"University of Vermont Medical Center",{"id":309,"slug":310,"hasResults":11,"nctId":311,"briefTitle":312,"officialTitle":312,"acronym":4,"eligibilityCriteria":313,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":314,"targetDuration":4,"studyType":22,"phases":315,"briefSummary":316,"conditions":317,"keywords":320,"overallStatus":328,"whyStopped":4,"lastUpdateSubmitDate":329,"lastUpdatePostDateStruct":330,"startDateStruct":332,"completionDateStruct":334,"leadSponsor":336,"locationsCount":53},"100610508","comparative-study-of-simulation-technologies-for-use-in-neonatal-resuscitation-training-for-rural-hospitals-100610508","NCT07228494","Comparative Study of Simulation Technologies for Use in Neonatal Resuscitation Training for Rural Hospitals","Inclusion Criteria:\n\n* at least 18 years of age\n* primary clinical role is either physicians, nurses, or respiratory therapists\n* have completed NRP® certification within the two years prior to enrollment\n* attend deliveries at participating hospital in study\n\nExclusion Criteria:\n\n\\- chronic neck pain, a previous neck injury that requires ongoing precautions, severe motion sickness or vertigo, and\u002For photosensitive epilepsy",{"count":123,"type":21},[24],"Conduct a randomized cluster non-inferiority clinical trial with teams of interprofessional neonatal clinicians from rural delivery hospitals. In this trial we will compare HoloBaby, a novel mixed reality simulator technology, to traditional high-technology simulator technology.",[318,319,31],"Interprofessional Education","Neonatal Resuscitation",[321,322,323,324,325,326,327],"HoloBaby","Neonatal resuscitation","interprofessional education","medical education","neonatal readiness","technology development","mixed reality","NOT_YET_RECRUITING","2026-01-12",{"date":331,"type":45},"2026-01-13",{"date":333,"type":21},"2026-01-08",{"date":335,"type":21},"2028-12-31",{"name":337,"class":52},"MaineHealth",{"id":339,"slug":340,"hasResults":11,"nctId":341,"briefTitle":342,"officialTitle":343,"acronym":344,"eligibilityCriteria":345,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":346,"targetDuration":4,"studyType":22,"phases":348,"briefSummary":349,"conditions":350,"keywords":4,"overallStatus":41,"whyStopped":4,"lastUpdateSubmitDate":353,"lastUpdatePostDateStruct":354,"startDateStruct":356,"completionDateStruct":358,"leadSponsor":360,"locationsCount":53},"100609775","fostering-agricultural-relationships-and-meaning---thriving-on-kinship-100609775","NCT07218965","Fostering Agricultural Relationships and Meaning - Thriving on Kinship","Fostering Agricultural Relationships and Meaning - Thriving on Kinship (FARM-TOK)","(FARM-TOK)","Inclusion Criteria:\n\n* 18 years of age or older\n* able to provide informed consent\n* understand English\n* have internet access\n* reside in an agricultural area\n* screen positive for loneliness by scoring at least 44 on the 20-item UCLA Loneliness Scale\n\nExclusion Criteria:\n\n* unable to give informed consent\n* non-English speaking\n* does not have consistent access to a phone and\u002For internet\n* reports being diagnosed with a neurological disorder or a current psychotic or bipolar 1 diagnosis\n* current suicidal or homicidal intent indicating a need for immediate hospitalization or treatment as determined by clinical interviewer",{"count":347,"type":21},65,[24],"This study aims to enroll 65 participants who will be assigned to one of two groups. Each group will receive an intervention consisting of six weekly sessions of 40-60 minutes each. Eligibility includes residing in an agricultural area and reporting loneliness or feeling alone or disconnected.",[351,352,31],"Loneliness","Social Isolation","2025-10-17",{"date":355,"type":45},"2025-10-21",{"date":357,"type":45},"2025-07-26",{"date":359,"type":21},"2026-07",{"name":161,"class":52},{"id":362,"slug":363,"hasResults":11,"nctId":364,"briefTitle":365,"officialTitle":365,"acronym":366,"eligibilityCriteria":367,"healthyVolunteers":16,"sex":17,"minAge":368,"maxAge":4,"enrollmentInfo":369,"targetDuration":4,"studyType":22,"phases":371,"briefSummary":372,"conditions":373,"keywords":4,"overallStatus":41,"whyStopped":4,"lastUpdateSubmitDate":383,"lastUpdatePostDateStruct":384,"startDateStruct":386,"completionDateStruct":388,"leadSponsor":390,"locationsCount":53},"100597159","rural-autistic-individuals---supporting-expression-100597159","NCT07054866","Rural Autistic Individuals - Supporting Expression","RAISE","Inclusion Criteria:\n\n* 1.1 Confirmed (preferably) or suspected diagnosis of ASD (autism spectrum disorder), or a receptive language impairment (i.e., difficulties with comprehension, Developmental Language Disorder), or both. Additional diagnoses, including ADHD (Attention Deficit and Hyperactivity Disorder), are acceptable. Siblings and cousins of these individuals are also welcome.\n\nOR 1.2 No diagnoses of ASD or DLD for unrelated control typically-developing participants.\n\n2\\. Normal hearing and normal vision (or corrected to normal with glasses or contacts).\n\n3\\. Ages 2+. 4. English as the dominant language of caregivers. 5. Caregivers who self-identify as living in a rural area. 6. The ability to verbally or physically respond is optional.\n\nExclusion Criteria:\n\n* 1\\. Poor hearing. 2. Inborn or acquired brain damage.","2 Years",{"count":370,"type":21},50,[24],"This research study investigates how hand gestures can support language comprehension and communication skills of hearing speaking, non-speaking, and\u002For minimally verbal individuals with Autism Spectrum Disorders (ASD), who are especially disadvantaged by the lack of accessible services in their rural communities. Individuals with other cognitive profiles, including Developmental Language Disorder (DLD), ADHD, Dyslexia, and others are welcome too. The study uses methods of eye tracking and recording of brain activity to understand how hand gestures adapted from signs from American Sign Language, such as \\[cry\\], can promote successful understanding of words like \"cry\". The overarching goal is to help families effectively utilize gestures to support communication with their children.",[374,375,376,377,31,378,379,380,381,382],"Autism Disorder","Language Development Disorders","ADHD","Typical Development","Children","Neuroimaging","Eye Tracking","EEG","fNIRS","2025-07-07",{"date":385,"type":45},"2025-07-10",{"date":387,"type":21},"2025-07",{"date":389,"type":21},"2027-07",{"name":391,"class":52},"Montana State University",{"id":393,"slug":394,"hasResults":11,"nctId":395,"briefTitle":396,"officialTitle":396,"acronym":397,"eligibilityCriteria":398,"healthyVolunteers":16,"sex":17,"minAge":399,"maxAge":400,"enrollmentInfo":401,"targetDuration":4,"studyType":22,"phases":403,"briefSummary":404,"conditions":405,"keywords":409,"overallStatus":328,"whyStopped":4,"lastUpdateSubmitDate":417,"lastUpdatePostDateStruct":418,"startDateStruct":420,"completionDateStruct":422,"leadSponsor":424,"locationsCount":4},"100594587","superstars-supermarket-support-for-a-primary-care-healthy-food-prescription-100594587","NCT07021391","SUPERSTARS: Supermarket Support for a Primary Care Healthy Food Prescription","SUPERSTARS","Inclusion Criteria:\n\n* primary care patient at one of 6 study practice sites\n* aged 21 or older\n* using MaineCare (Medicaid) or MaineHealth Assisted Care\n* use of Hannaford Supermarket for at lest half of all household grocery shopping\n* member of Hannaford loyalty program for at least 6 months\n* at least 2 visits to primary care site over past 2 years\n\nExclusion Criteria:\n\n* under 21 years of age\n* older than 90 years of age\n* use of private insurance\n* not a Hannaford Supermarket shopper\n* not the primary household shopper\n* if primary household shopper, not using Hannaford Supermarket for more than half of grocery purchases\n* Hannford loyalty program member for less than 6 months\n* less than 2 primary care visits past 2 years","21 Years","90 Years",{"count":402,"type":21},500,[24],"Few Americans meet dietary recommendations. Poor diet is a major contributor to increasing prevalence of diabetes and obesity, which are negatively impacting long term health, quality of life, and healthcare costs, particularly among low-income, racial and ethnic minority, and rural populations in the U.S. To help address these inequities, produce prescription programs are being implemented in many health care settings. However, key research gaps and programmatic barriers remain. In the proposed project, the investigators will use research, education, and extension to improve nutrition security in rural underserved communities and deliver science-based knowledge to consumers, allowing them to make informed, practical decisions that can improve health equity. The project goal is to implement and rigorously evaluate an innovative primary-care based healthy food prescription that is paired with incentives to use the local supermarket's established healthy food shelf-tag labeling system to increase healthy food choices at the point of purchase. The investigators will: 1) assess the program's impact on participants' food and nutrition security, 2) assess the program's impact on participants' supermarket purchases and diet, and explore the program's impact on health, and 3) use the research findings to engage health systems, nutrition educators, and communities in evidence-based strategies to improve nutrition security. The program has the potential to sustainably encourage healthy food choices where decisions matter-in the supermarket, using existing supermarket resources. Improving purchasing patterns by increasing sales of less processed and whole foods, could also positively affect industry offerings and sustainability of the agricultural system as a whole.",[406,407,408,31],"Healthy Food Choice","Incentives","Low Income Population",[410,411,412,413,414,415,416],"Healthy food Prescription","Primary care","food security","nutrition security","supermarket","healthy food incentive","shopping behavior","2025-06-04",{"date":419,"type":45},"2025-06-15",{"date":421,"type":21},"2025-07-01",{"date":423,"type":21},"2026-11-30",{"name":425,"class":52},"University of New England"]