[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"scalp-block\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:scalp-block":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,44,74],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":28,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":33,"lastUpdatePostDateStruct":34,"startDateStruct":37,"completionDateStruct":39,"leadSponsor":41,"locationsCount":4},"100631127","effect-of-scalp-block-on-intraoperative-hemodynamics-and-postoperative-pain-in-craniotomy-patients-100631127",false,"NCT07496632","Effect of Scalp Block on Intraoperative Hemodynamics and Postoperative Pain in Craniotomy Patients\"","Efficacy of Scalp Block on Intraoperative Hemodynamic Responses and Postoperative Analgesia in Patients Undergoing Craniotomy","Inclusion Criteria:\n\n* Age 18-64 years.\n* ASA (American Society of Anesthesiologists) physical status I or II.\n* Patients scheduled for elective supratentorial craniotomy.\n* BMI of 18 to 30 kg\u002Fm².\n* GCS score of 9 to 15.\n\nExclusion Criteria:\n\n* Patient with instable blood pressure and heart rate.\n* Known allergy or hypersensitivity to local anesthetics.\n* Coagulation disorders or current anticoagulant therapy.\n* Infection at the injection site or systemic infection.\n* Patients with open skull defects.","ALL","18 Years","64 Years",{"count":20,"type":21},72,"ESTIMATED","INTERVENTIONAL",[24],"NA","The goal of this clinical trial is to learn if an ultrasound-guided scalp block can improve intraoperative hemodynamic stability and provide better postoperative pain relief in adult patients undergoing elective supratentorial craniotomy. The main questions it aims to answer are:\n\nDoes ultrasound-guided scalp block reduce changes in heart rate and blood pressure during surgery compared with surgical site infiltration?\n\nDoes ultrasound-guided scalp block decrease postoperative pain and opioid requirements in the first 24 hours after craniotomy?\n\nResearchers will compare patients receiving an ultrasound-guided scalp block to those receiving standard surgical site infiltration to see if the scalp block provides better perioperative hemodynamic control and postoperative analgesia.\n\nParticipants will:\n\nReceive general anesthesia with either ultrasound-guided scalp block or surgical site infiltration\n\nHave heart rate, blood pressure, and other hemodynamic parameters monitored throughout surgery\n\nReceive standard postoperative pain management, with pain scores recorded at 0, 2, 6, 12, and 24 hours\n\nReceive opioids as needed based on pain scores, with total opioid consumption and time to first analgesic dose recorded\n\nBe monitored for adverse events, including nausea, vomiting, sedation, and block-related complications",[27],"Scalp Block",[27,29,30,31],"Intraoperative Hemodynamic Responses","Postoperative Analgesia","Craniotomy","NOT_YET_RECRUITING","2026-03-27",{"date":35,"type":36},"2026-04-01","ACTUAL",{"date":38,"type":21},"2026-04",{"date":40,"type":21},"2026-10",{"name":42,"class":43},"Bangladesh Medical University","OTHER",{"id":45,"slug":46,"hasResults":11,"nctId":47,"briefTitle":48,"officialTitle":49,"acronym":4,"eligibilityCriteria":50,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":51,"enrollmentInfo":52,"targetDuration":4,"studyType":22,"phases":54,"briefSummary":55,"conditions":56,"keywords":60,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":64,"lastUpdatePostDateStruct":65,"startDateStruct":67,"completionDateStruct":69,"leadSponsor":71,"locationsCount":73},"100596297","when-to-block-timing-of-scalp-block-in-craniotomy-100596297","NCT07043621","When to Block? Timing of Scalp Block in Craniotomy","Scalp Block Before Incision or Before Emergence in Craniotomy: A Randomized Controlled Evaluation of Effectiveness and Recovery Quality Via QoR-40","Inclusion Criteria:\n\n* Patients aged between 18 and 80 years.\n* Scheduled for craniotomy under general anesthesia.\n* ASA physical status classification I to III.\n* Glasgow Coma Scale (GCS) score of 15 at the time of emergence from anesthesia.\n* Provide informed consent to participate in the study.\n\nExclusion Criteria:\n\n* Chronic use of analgesic medications prior to surgery.\n* Glasgow Coma Scale (GCS) score below 15 postoperatively.\n* Allergy or hypersensitivity to local anesthetics or opioids used in the study.\n* Contraindications for scalp block or patient-controlled analgesia.\n* Patients with severe hepatic, renal, or cardiac dysfunction.\n* Patients unable to comprehend or complete the QoR-40 questionnaire.","80 Years",{"count":53,"type":21},60,[24],"This study aims to evaluate the effect of scalp block timing-whether administered preoperatively or postoperatively-on postoperative recovery quality in patients undergoing craniotomy. The recovery quality will be assessed using the validated Quality of Recovery-40 (QoR-40) questionnaire. A total of 60 patients, aged 18-80 years, classified as ASA I-III and with a Glasgow Coma Scale (GCS) score of 15 upon admission to the recovery unit, will be enrolled. The primary outcome is the QoR-40 score. Secondary outcomes include hemodynamic changes and pain intensity measured by the Visual Analog Scale (VAS).",[27,57,58,59],"Regional Anesthesia","Craniotomy Surgery","QoR-40",[27,61,62,63],"Craniotomy surgery","analgesia","postoperative pain","2025-06-27",{"date":66,"type":36},"2025-06-29",{"date":68,"type":21},"2025-06",{"date":70,"type":21},"2025-12",{"name":72,"class":43},"Sakarya University",1,{"id":75,"slug":76,"hasResults":11,"nctId":77,"briefTitle":78,"officialTitle":78,"acronym":4,"eligibilityCriteria":79,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":80,"enrollmentInfo":81,"targetDuration":4,"studyType":22,"phases":83,"briefSummary":84,"conditions":85,"keywords":4,"overallStatus":90,"whyStopped":4,"lastUpdateSubmitDate":91,"lastUpdatePostDateStruct":92,"startDateStruct":94,"completionDateStruct":95,"leadSponsor":97,"locationsCount":73},"100592476","dexmedetomidine-as-an-adjuvant-to-bupivacaine-in-scalp-block-versus-bupivacaine-alone-for-postoperative-pain-management-in-patients-undergoing-craniotomy-100592476","NCT06993922","Dexmedetomidine as an Adjuvant to Bupivacaine in Scalp Block Versus Bupivacaine Alone for Postoperative Pain Management in Patients Undergoing Craniotomy","Inclusion Criteria:\n\n* Age from 18 to 65 years.\n* Both sexes.\n* American Society of Anesthesiologists (ASA) physical status I or II.\n* Undergoing supratentorial elective planned craniotomies.\n\nExclusion Criteria:\n\n* Patients refusal.\n* History of known allergy to the used local anesthetic or dexmedetomidine.\n* Bleeding disorders.\n* Evidence of local infection at the site of injection.\n* Emergency craniotomy.\n* Psychotic disorder.\n* Patients who will not be extubated in the operating room after surgery.","65 Years",{"count":82,"type":21},50,[24],"This study aims to compare dexmedetomidine as an adjuvant to bupivacaine in scalp block versus bupivacaine alone for postoperative pain management in patients undergoing craniotomy.",[86,87,88,27,89,31],"Dexmedetomidine","Adjuvant","Bupivacaine","Postoperative Pain","RECRUITING","2025-05-29",{"date":93,"type":36},"2025-05-30",{"date":91,"type":36},{"date":96,"type":21},"2025-11-01",{"name":98,"class":43},"Ain Shams University"]