[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"scar-improvement\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:scar-improvement":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,42],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":4,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":30,"lastUpdatePostDateStruct":31,"startDateStruct":34,"completionDateStruct":36,"leadSponsor":38,"locationsCount":41},"100053273","management-of-abdominal-post-surgical-scar-with-ozoaqua-versus-standard-care-100053273",false,"NCT07678372","Management of Abdominal Post-surgical Scar With Ozoaqua Versus Standard Care","Prospective, Randomized, Evaluator-blinded Clinical Study to Compare a Post-surgical Scar Care Protocol Using OzoAqua Products Versus Standard Care in Open Abdominal Surgery.","Inclusion Criteria:\n\n* Age ≥18 years\n* Scheduled open abdominal surgery\n* Primary wound closure\n* Assessable linear abdominal scar\n* Signed informed consent\n* Ability to complete 3-month follow-up\n\nExclusion Criteria:\n\n* Known allergy to treatment components\n* Active infection or significant dehiscence in the immediate postoperative period\n* Planned use of specific scar treatments -silicone products, laser therapy, local corticosteroids- except as clinical rescue treatment\n* Inability to complete follow-up\n* Participation in another study that may interfere with wound healing","FEMALE","18 Years",{"count":19,"type":20},144,"ESTIMATED","INTERVENTIONAL",[23],"NA","A prospective, randomized clinical study with a blinded evaluator to compare a post-surgical abdominal scar care protocol using Ozoaqua products versus standard care in patients undergoing open abdominal surgery. The primary objective is to assess whether the use of Ozoaqua, initiated in the immediate postoperative period according to wound evolution, improves abdominal scar quality at 3 months compared with usual care.\n\nThe proposed design is an initial single-center study at the Clínica Universidad de Navarra, with 1:1 random allocation to two parallel arms: an intervention group receiving standard care plus Ozoaqua ozonated soap and oil, and a control group receiving standard care only. The primary scar assessment will be performed by a blinded evaluator, while treatment will be open-label due to the nature of the topical intervention.\n\nThe target population consists of adult patients undergoing scheduled open abdominal surgery, with primary wound closure and an assessable linear abdominal scar. Follow-up will be integrated into routine clinical care, including an in-hospital phase during the first postoperative days and outpatient visits at approximately 2 weeks, 1 month and 3 months, with the latter being the main study visit.\n\nThe primary endpoint will be scar quality at 3 months, assessed using the POSAS scale, particularly the blinded observer score. Secondary endpoints will include the patient POSAS score, scar evolution, wound complications, pain, pruritus, satisfaction, cutaneous adverse events, rescue treatments and adherence.",[26,27,28],"Wound Healing","Abdominal Surgery","Scar Improvement","NOT_YET_RECRUITING","2026-07-09",{"date":32,"type":33},"2026-07-13","ACTUAL",{"date":35,"type":20},"2026-07-06",{"date":37,"type":20},"2027-07-06",{"name":39,"class":40},"Laboratorios Ozoaqua","INDUSTRY",1,{"id":43,"slug":44,"hasResults":11,"nctId":45,"briefTitle":46,"officialTitle":47,"acronym":48,"eligibilityCriteria":49,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":50,"enrollmentInfo":51,"targetDuration":4,"studyType":21,"phases":53,"briefSummary":54,"conditions":55,"keywords":57,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":63,"lastUpdatePostDateStruct":64,"startDateStruct":66,"completionDateStruct":68,"leadSponsor":70,"locationsCount":4},"100604017","tape-application-protocol-for-enhanced-scars-100604017","NCT07144046","Tape Application Protocol for Enhanced Scars","The Effect of Long-term Micropore Coverage on Cosmetic Outcomes After Mastectomy","TAPES","Inclusion Criteria:\n\n* Women undergoing mastectomi without primary recontruction\n* BMI between 18-5 and 35\n* Age between 18 and 80\n\nExclusion Criteria:\n\n* Known bandaid allergy\n* In need of Mepilex Border OP after surgery\n* Concurrent treatment with systemic steroid treatment or other immunosuppresants\n* Post surgical haematoma that requires surgical intervention\n* Known tendency to kelloid or hypertrophic scar formation","80 Years",{"count":52,"type":20},90,[23],"What is the purpose of this study? The Investigators want to find out whether applying Micropore surgical tape to the medial half of the mastectomy scar for 3 months helps improve its appearance after 12 months, compared to no intervention.\n\nWhy is this study important? Scars can cause discomfort and affect how people feel about their bodies. The tape is thought to reduce stress on healing skin and possibly lead to a better-looking scar. But The Investigators need strong evidence to know whether it really helps.\n\nHow will the study be done?\n\nThis is a randomized, observer-blinded trial.\n\nWomen having mastectomy are randomly assigned to either receive the tape on half their scar or receive no tape.\n\nA plastic surgeon and a breast surgeon-who do not know which side had tape-will evaluate wounds using photos after 3 and 12 months.\n\nPatients will also rate their scars using a questionnaire (POSAS), giving their personal view on color, thickness, stiffness, and symptoms like itch or pain.\n\nWhat else are The Investigators looking at?\n\nThe Investigators will examine whether the treated half of the scar looks better than the untreated half within the same woman-this helps control for individual skin differences.\n\nThe Investigators will also compare treated versus untreated areas across different women to see if there is a consistent benefit.\n\nIf the untaped half of scars looks different from control scars, this may suggest differences between the groups that affect results.\n\nWhat will this study reveal? It will show whether using the tape improves cosmetic outcomes after mastectomy, and whether patients and clinicians agree on how scars heal. The findings may guide better post-surgery care to reduce scars and improve confidence and quality of life.",[28,56],"Cosmetic Outcome",[58,59,60,61,62],"Cosmetic Scar Evaluation","Long term wound dressing","Scar formation","Mastectomy","Breast Cancer","2025-08-20",{"date":65,"type":33},"2025-08-27",{"date":67,"type":20},"2025-09-01",{"date":69,"type":20},"2028-09-01",{"name":71,"class":72},"Herlev Hospital","OTHER"]