[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"sciatica-due-to-intervertebral-disc-disorder\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:sciatica-due-to-intervertebral-disc-disorder":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,48],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":29,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":36,"lastUpdatePostDateStruct":37,"startDateStruct":40,"completionDateStruct":42,"leadSponsor":44,"locationsCount":47},"100627091","two-leg-rotation-and-sciatica-100627091",false,"NCT07444125","Two-leg Rotation and Sciatica","Effect of Adding Two Leg-rotation to Standard Physical Therapy in the Treatment of Sciatica Secondary to Lumbar Discogenic Lesions.","(MWM)","Inclusion Criteria:\n\n* Both genders.\n\n  * Age between 18 and 50\n  * Have lumbar discogenic lesions.\n  * Having sciatica symptoms extending down to the knee.\n\nExclusion Criteria:\n\n* Surgical operation in the lumbar spine\n* Severe discogenic lesions with bladder or fecal incontinence or progressive muscular weakness.\n* Piriform syndrome.","ALL","18 Years","50 Years",{"count":21,"type":22},70,"ESTIMATED","INTERVENTIONAL",[25],"NA","this study including the application of a specific technique of Mulligan mobilization calles 2 leg rotation on patients having lumbar discogenic lesion with sciatica. this technique is designed to address sciatic pain and proposed to reduce sciatica by opening the intervertebral foramnia. However, there is no systematic evedince supporting its clinical effect",[28],"Sciatica Due to Intervertebral Disc Disorder",[30,31,32,33,34],"Sciatica","lumbar disc lesion","Mulligan concept","function","physiotherapy","RECRUITING","2026-04-30",{"date":38,"type":39},"2026-05-07","ACTUAL",{"date":41,"type":39},"2026-03-15",{"date":43,"type":22},"2026-05-30",{"name":45,"class":46},"University of Hail","OTHER",1,{"id":49,"slug":50,"hasResults":11,"nctId":51,"briefTitle":52,"officialTitle":52,"acronym":53,"eligibilityCriteria":54,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":55,"targetDuration":4,"studyType":23,"phases":57,"briefSummary":58,"conditions":59,"keywords":61,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":70,"lastUpdatePostDateStruct":71,"startDateStruct":73,"completionDateStruct":75,"leadSponsor":77,"locationsCount":5},"100356729","transforaminal-epidural-injection-in-acute-sciatica-100356729","NCT03924791","Transforaminal Epidural Injection in Acute Sciatica","TEIAS","Inclusion Criteria:\n\n* Diagnosed with sciatica by GP\n* NRS leg pain of 6 or more on a 10-point NRS scale\n* Minimum duration of symptoms of 3 weeks and maximum duration of 8 weeks\n\nExclusion Criteria:\n\n* Age under 18 years\n* Condition preventing to receive transforaminal epidural injection\n* Severe scoliosis\n* Transforaminal epidural injection received in 6 months before randomization date\n* Surgery for sciatica at the same level\n* Surgery for sciatica at another level within one year before inclusion\n* Pregnancy",{"count":56,"type":22},142,[25],"Patients suffering from sciatica are treated conservatively for the first 8 weeks due to the favourable prognosis. This period is preferably extended up to 14-16 weeks after which patients may opt for surgery. However, patients may experience severe discomfort due to pain in the leg which can lead to decreased physical activity and socio-economic problems. An adequate therapy to alleviate symptoms during this period of 'wait-and-see' is lacking. In this study, patients will be randomized to treatment with transforaminal epidural injections or standard oral pain medication.",[30,28,60],"Sciatic Radiculopathy",[30,62,63,64,65,66,67,68,69],"Acute sciatica","Transforaminal epidural injection","Leg pain","Lumbar spine","Back pain","Lumbar surgery","Herniated intervertebral lumbar disk","Cost-effectiveness","2023-10-18",{"date":72,"type":39},"2023-10-19",{"date":74,"type":39},"2019-06-01",{"date":76,"type":22},"2026-07",{"name":78,"class":46},"C.L.A.Vleggeert-Lankamp"]