[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"scleroderma-localized\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:scleroderma-localized":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,4,0,[8,45,80,106],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":17,"sex":18,"minAge":4,"maxAge":19,"enrollmentInfo":20,"targetDuration":23,"studyType":24,"phases":4,"briefSummary":25,"conditions":26,"keywords":4,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":33,"lastUpdatePostDateStruct":34,"startDateStruct":37,"completionDateStruct":39,"leadSponsor":41,"locationsCount":44},"100194584","morphea-in-adults-and-children-mac-cohort-study-a-morphea-registry-and-dna-repository-100194584",false,"NCT01808937","Morphea in Adults and Children (MAC) Cohort Study: A Morphea Registry and DNA Repository","Immunologic and Genetic Profiles in Subsets of Morphea Patients","MAC","Inclusion Criteria:\n\n1. Patient must have a clinical diagnosis of morphea confirmed by the primary investigator and by histopathological examination.\n2. Ages 0-90 years old\n3. Children must weigh more than 20 lbs. in order to satisfy Children's Medical Center policy for the maximum amount of blood drawn in a 24 hour period.\n4. Patient or legal guardian must be able to speak and read at a 6th grade reading level.\n5. Both male and female patients will be eligible\n6. All races and ethnic backgrounds will be included\n7. Relationships to proband: All patients with morphea will be included. A patient's family history will be reviewed and if there is a family history of morphea or systemic sclerosis then we will give the study patient the investigator's contact information and ask the family member to call the study team to answer any questions and enroll them in the study if they choose to do so.\n8. Ability to give informed consent: Patients must be able to give informed consent or they will give assent with parent or guardian consent as a minor to be a part of the morphea registry.\n\nExclusion Criteria:\n\n\\- Patients who have been coded as morphea (701.0), but do not have morphea\u002Flocalized scleroderma (examples: steroid atrophy, acquired keratoderma, keloids, nephrogenic fibrosing dermopathy, systemic sclerosis, lichen sclerosis)",true,"ALL","90 Years",{"count":21,"type":22},500,"ESTIMATED","6 Years","OBSERVATIONAL","The Morphea in Adults and Children (MAC) cohort is the first registry for both children and adults with morphea (also known as localized scleroderma) in the country. The purpose of the registry is to learn more about morphea, specifically:\n\n* How morphea behaves over time\n* How frequently specific problems occur along with morphea (for example, arthritis)\n* Whether morphea has an autoimmune background",[27,28,29,30,31],"Scleroderma, Localized","Morphea","Frontal Linear Scleroderma en Coup de Sabre","Scleroderma, Circumscribed","Scleroderma, Linear","RECRUITING","2026-05-07",{"date":35,"type":36},"2026-05-12","ACTUAL",{"date":38,"type":36},"2007-05",{"date":40,"type":22},"2028-01",{"name":42,"class":43},"University of Texas Southwestern Medical Center","OTHER",1,{"id":46,"slug":47,"hasResults":11,"nctId":48,"briefTitle":49,"officialTitle":50,"acronym":4,"eligibilityCriteria":51,"healthyVolunteers":11,"sex":18,"minAge":52,"maxAge":4,"enrollmentInfo":53,"targetDuration":4,"studyType":55,"phases":56,"briefSummary":58,"conditions":59,"keywords":66,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":71,"lastUpdatePostDateStruct":72,"startDateStruct":74,"completionDateStruct":76,"leadSponsor":78,"locationsCount":44},"100615465","investigating-the-effectiveness-of-the-biopsychosocial-model-based-exercise-approach-in-children-and-adults-diagnosed-with-scleroderma-100615465","NCT07292961","Investigating the Effectiveness of the Biopsychosocial Model-Based Exercise Approach in Children and Adults Diagnosed With Scleroderma","Investigating the Effectiveness of the Biopsychosocial Model-Based Exercise Approach (BETY) in Children and Adults Diagnosed With Scleroderma: A Single-Blind Randomized Controlled Trial","\\*For a child diagnosed with scleroderma\\*\n\nInclusion Criteria:\n\n* Cases diagnosed with scleroderma,\n* Cases aged 7-18 years will be included.\n\nExclusion Criteria:\n\n* Advanced heart\u002Flung\u002Fliver\u002Fkidney disease, neurological disease, and malignancies\n* Cases that are not willing to participate in the study will be excluded.\n* History of developmental delay\n* Having participated in a regular exercise program for the past 3 months\n* Individuals who are not willing to participate in the study\n\n\\*For adults diagnosed with scleroderma\\*\n\nInclusion Criteria:\n\n* Individuals diagnosed with scleroderma,\n* Individuals over the age of 18 will be included.\n\nExclusion Criteria:\n\n* Advanced heart\u002Flung\u002Fliver\u002Fkidney disease, neurological disease, and malignancies\n* Individuals who are not willing to participate in the study will be excluded.\n* Having participated in a regular exercise program for the past 3 months\n* Individuals who are not willing to participate in the study","7 Years",{"count":54,"type":22},48,"INTERVENTIONAL",[57],"NA","This study aims to investigate the effectiveness of BETY, an exercise approach based on the biopsychosocial model, in children and adults diagnosed with scleroderma.",[60,27,61,62,63,64,65],"Scleroderma","Scleroderma Systemic","Scleroderma (Limited and Diffuse)","Systemic Sclerosis (SSc)","Systemic Sclerosis - 2013 ACR\u002FEULAR Classification Criteria","Juvenile Systemic Sclerosis",[67,68,69,70],"biopsychosocial model","exercise","scleroderma","juvenile scleroderma","2025-12-06",{"date":73,"type":36},"2025-12-18",{"date":75,"type":36},"2025-12-04",{"date":77,"type":22},"2027-12-04",{"name":79,"class":43},"Hacettepe University",{"id":81,"slug":82,"hasResults":11,"nctId":83,"briefTitle":84,"officialTitle":85,"acronym":4,"eligibilityCriteria":86,"healthyVolunteers":11,"sex":18,"minAge":52,"maxAge":4,"enrollmentInfo":87,"targetDuration":89,"studyType":24,"phases":4,"briefSummary":90,"conditions":91,"keywords":93,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":98,"lastUpdatePostDateStruct":99,"startDateStruct":101,"completionDateStruct":103,"leadSponsor":105,"locationsCount":44},"100607016","patients-diagnosed-with-scleroderma-physical-performance-and-functionality-100607016","NCT07183072","Patients Diagnosed With Scleroderma: Physical Performance and Functionality","Investigating the Relationship Between the Biopsychosocial Status of Individuals Diagnosed With Scleroderma and Their Physical Performance and Functionality","\\*For a child diagnosed with scleroderma\\*\n\nInclusion Criteria:\n\n* Cases diagnosed with scleroderma,\n* Cases aged 7-18 years will be included.\n\nExclusion Criteria:\n\n* Advanced heart\u002Flung\u002Fliver\u002Fkidney disease, neurological disease, and malignancies\n* Cases that are not willing to participate in the study will be excluded.\n* Having participated in a regular exercise program for the past 3 months\n* Individuals who are not willing to participate in the study\n\n\\*For adults diagnosed with scleroderma\\*\n\nInclusion Criteria:\n\n* Individuals diagnosed with scleroderma,\n* Individuals over the age of 18 will be included.\n\nExclusion Criteria:\n\n* Advanced heart\u002Flung\u002Fliver\u002Fkidney disease, neurological disease, and malignancies\n* Individuals who are not willing to participate in the study will be excluded.\n* Having participated in a regular exercise program for the past 3 months\n* Individuals who are not willing to participate in the study",{"count":88,"type":22},50,"2 Weeks","Physical functionality and performance are important for individuals diagnosed with scleroderma. There is a need to address children and adults diagnosed with scleroderma comprehensively and to evaluate them on a biopsychosocial basis to support their disease management. In light of all this literature, the aim was to evaluate the biopsychosocial characteristics of both pediatric and adult scleroderma patients and to examine their physical performance and functionality.\n\nAdditionally, this study aims to identify effective tests that can be used in future research to assess physical performance and functionality in individuals diagnosed with scleroderma.",[63,60,62,27,92],"Functionality",[94,69,95,96,97],"Juvenile scleroderma","systemic sclerosis","physical performance","functionality","2025-09-13",{"date":100,"type":36},"2025-09-19",{"date":102,"type":36},"2025-08-04",{"date":104,"type":22},"2027-08-04",{"name":79,"class":43},{"id":107,"slug":108,"hasResults":11,"nctId":109,"briefTitle":110,"officialTitle":111,"acronym":4,"eligibilityCriteria":112,"healthyVolunteers":11,"sex":18,"minAge":52,"maxAge":4,"enrollmentInfo":113,"targetDuration":89,"studyType":24,"phases":4,"briefSummary":114,"conditions":115,"keywords":117,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":98,"lastUpdatePostDateStruct":118,"startDateStruct":119,"completionDateStruct":120,"leadSponsor":121,"locationsCount":44},"100607009","patients-diagnosed-with-scleroderma-and-their-chewing-and-swallowing-performance-100607009","NCT07182981","Patients Diagnosed With Scleroderma and Their Chewing and Swallowing Performance","Investigating the Relationship Between the Biopsychosocial Status of Patients Diagnosed With Scleroderma and Their Chewing and Swallowing Performance","For a child diagnosed with scleroderma:\n\nInclusion Criteria:\n\n* Cases diagnosed with scleroderma,\n* Cases aged 7-18 years will be included.\n\nExclusion Criteria:\n\n* Advanced heart\u002Flung\u002Fliver\u002Fkidney disease, neurological disease, and malignancies\n* Cases that are not willing to participate in the study will be excluded.\n* Having participated in a regular exercise program for the past 3 months\n* Individuals who are not willing to participate in the study\n\nFor adults diagnosed with scleroderma:\n\nInclusion Criteria:\n\n* Individuals diagnosed with scleroderma,\n* Individuals over the age of 18 will be included.\n\nExclusion Criteria:\n\n* Advanced heart\u002Flung\u002Fliver\u002Fkidney disease, neurological disease, and malignancies\n* Individuals who are not willing to participate in the study will be excluded.\n* Having participated in a regular exercise program for the past 3 months\n* Individuals who are not willing to participate in the study",{"count":88,"type":22},"It is recommended to focus on the physical functionality, chewing, and swallowing performance of individuals diagnosed with scleroderma. There is a need to address children and adults diagnosed with scleroderma comprehensively and to evaluate them on a biopsychosocial basis to support their disease management. The aim was to assess the biopsychosocial characteristics of both children and adults diagnosed with scleroderma and to examine their chewing and swallowing performance.\n\nAdditionally, this study aims to identify effective scales that can be used in future research to assess chewing and swallowing in individuals diagnosed with scleroderma.",[63,60,62,27,116],"Swallowing",[94,69,95],{"date":100,"type":36},{"date":102,"type":36},{"date":104,"type":22},{"name":79,"class":43}]