[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"sclerotherapy\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:sclerotherapy":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,46,76],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":4,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":34,"lastUpdatePostDateStruct":35,"startDateStruct":38,"completionDateStruct":40,"leadSponsor":42,"locationsCount":45},"100645143","ndyag-laser-combined-with-injection-sclerotherapy-versus-diode-laser-in-the-treatment-of-reticular-veins-and-telangiectasias-using-clacs-technique-100645143",false,"NCT07678697","Nd:YAG Laser Combined With Injection Sclerotherapy Versus Diode Laser in the Treatment of Reticular Veins and Telangiectasias Using CLaCS Technique","Comparative Study Between Nd:YAG Laser Combined With Injection Sclerotherapy Versus Diode Laser in the Treatment of Reticular Veins and Telangiectasias Using CLaCS Technique","Inclusion Criteria:\n\n* Patients aged 18-60 years.\n* Both sexes.\n* Presence of reticular veins and\u002For telangiectasias (CEAP classification C1).\n* Fitzpatrick skin types II-V.\n* Patients seeking cosmetic treatment.\n\nExclusion Criteria:\n\n* Pregnancy or lactation.\n* History of deep vein thrombosis.\n* Coagulation disorders.\n* Allergy to sclerosant agents.\n* Active skin infection at treatment site.\n* Previous treatment of target veins within 6 months.\n* Great saphenous vein or short saphenous vein incompetence.\n* Deep venous insufficiency or thrombosis.\n* Abnormal venous duplex findings.","ALL","18 Years","60 Years",{"count":20,"type":21},80,"ESTIMATED","INTERVENTIONAL",[24],"NA","This study aims to compare the efficacy (in terms of vein clearance) and safety of Nd:YAG laser combined with injection sclerotherapy versus diode laser combined with injection sclerotherapy in the treatment of reticular veins and telangiectasias using the Cryo-Laser and Cryo-Sclerotherapy (CLaCS) technique.",[27,28,29,30,31,32],"Nd:YAG Laser","Sclerotherapy","Diode Laser","Reticular Veins","Telangiectasias","CLaCS Technique","RECRUITING","2026-06-25",{"date":36,"type":37},"2026-07-01","ACTUAL",{"date":39,"type":37},"2026-06-01",{"date":41,"type":21},"2026-12-01",{"name":43,"class":44},"Ain Shams University","OTHER",1,{"id":47,"slug":48,"hasResults":11,"nctId":49,"briefTitle":50,"officialTitle":51,"acronym":4,"eligibilityCriteria":52,"healthyVolunteers":11,"sex":53,"minAge":17,"maxAge":54,"enrollmentInfo":55,"targetDuration":57,"studyType":58,"phases":4,"briefSummary":59,"conditions":60,"keywords":64,"overallStatus":66,"whyStopped":4,"lastUpdateSubmitDate":67,"lastUpdatePostDateStruct":68,"startDateStruct":70,"completionDateStruct":72,"leadSponsor":74,"locationsCount":4},"100629972","laparoscopic-sclerotherapy-for-the-management-of-ovarian-endometriomas-100629972","NCT07481617","Laparoscopic Sclerotherapy for the Management of Ovarian Endometriomas","Laparoscopic Sclerotherapy for Management of Endometriomas: A Pilot Study Evaluating Impact on Ovarian Reserve","Inclusion Criteria:\n\n* English speaking\n* Age of 18 or greater\n* At least one ovarian endometrioma \\> 4 cm in size\n* Desires to proceed with surgical management of the endometrioma\n\nExclusion Criteria:\n\n* Known diminished ovarian reserve (AMH \\\u003C 1.0)\n* Known allergies to ethanol solutions\n* Pregnancy","FEMALE","55 Years",{"count":56,"type":21},20,"6 Weeks","OBSERVATIONAL","The objective of this study is to evaluate the effect of laparoscopic sclerotherapy on ovarian reserve and its overall efficacy in the treatment of endometriomas. Ovarian reserve will be assessed using preoperative and postoperative anti-Müllerian hormone (AMH) levels and antral follicle count (AFC). Traditionally, ovarian endometriomas are managed by complete cystectomy; however, multiple studies including a large systematic review and meta-analysis-have demonstrated that cystectomy significantly reduces ovarian reserve, with an average decline in AMH of 1.77 ng\u002FmL within one to six weeks postoperatively without recovery to baseline after many months. Sclerotherapy has historically been a potential alternative, typically performed by interventional radiology via transvaginal, transabdominal, or transgluteal drainage. This percutaneous approach, however, precludes direct visualization of the cyst and surgical management of concurrent conditions including endometriosis peritoneal disease, excision, adhesions, or tubal disease.\n\nSeveral studies have explored the feasibility and effectiveness of laparoscopic sclerotherapy, reporting encouraging results regarding its safety, increased AFC compared with cystectomy, and comparable pregnancy rates. Nonetheless, none of these studies have been conducted in the United States, and few have utilized a laparoscopic approach. Further research is therefore warranted to establish the accessibility and reproducibility of this technique. The investigators aim to conduct the first U.S.-based study evaluating the impact of laparoscopic sclerotherapy on ovarian reserve. The primary outcome will be the change in AMH and AFC at six weeks postoperatively. Consistent with prior evidence, the investigators hypothesize that laparoscopic sclerotherapy will result in a smaller decline in ovarian reserve compared with traditional cystectomy.",[61,62,28,63],"Endometriosis","Endometrioma","Laparoscopy",[65],"laparoscopic sclerotherapy","NOT_YET_RECRUITING","2026-04-23",{"date":69,"type":37},"2026-04-29",{"date":71,"type":21},"2026-05-16",{"date":73,"type":21},"2027-08-30",{"name":75,"class":44},"Northwestern University",{"id":77,"slug":78,"hasResults":11,"nctId":79,"briefTitle":80,"officialTitle":81,"acronym":82,"eligibilityCriteria":83,"healthyVolunteers":84,"sex":53,"minAge":17,"maxAge":85,"enrollmentInfo":86,"targetDuration":4,"studyType":22,"phases":88,"briefSummary":89,"conditions":90,"keywords":94,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":100,"lastUpdatePostDateStruct":101,"startDateStruct":103,"completionDateStruct":105,"leadSponsor":107,"locationsCount":5},"100513231","ethanol-sclerotherapy-prior-to-art-100513231","NCT05962775","Ethanol Sclerotherapy Prior to ART","The Impact of Ethanol Sclerotherapy Before ART (Assisted Reproductive Technology) Cycle on Cumulative Live Birth Rate in Infertile Women With Endometrioma: A Randomized Controlled Trial","START","Inclusion Criteria:\n\n* AMH\\>0.3 ng\u002Fml\n* unilateral\u002Fbilateral endometrioma\n* Endometrioma diameter 40-100 mm\n\nExclusion Criteria:\n\n* 3 or more IVF\u002Fembryo transfer failure\n* Menstrual cycle abnormalities\n* Male Factor infertility\n* Presence of uterine fibroids\n* Presence of hydrosalpinx\n* Presence of uterine abnormalities\n* Suspicion of malignancy according to International Ovarian Tumor Analysis criteria",true,"40 Years",{"count":87,"type":21},84,[24],"The goal of this randomized controlled trial is to assess the impact of ethanol sclerotherapy on ART cycle outcomes. The main questions it aims to answer are:\n\n1. Does ethanol sclerotherapy before ART cycle has any impact on cumulative live birth rate in patients with endometrioma?\n2. Does ethanol sclerotherapy improve chronic pelvic pain, dysmenorrhea, complications during oocyte retrieval, response to ovarian stimulation (number of mature oocytes retrieved), and pregnancy loss rates?\n\nInfertile patients with endometrioma between 4-10 cm who are scheduled for ART within 2 cycles will be randomized to ethanol sclerotherapy or no intervention.",[62,91,28,92,93],"Infertility","ART","IVF",[95,96,97,98,99],"endometrioma","ethanol sclerotherapy","assisted reproductive technology","in vitro fertilization","cumulative live birth rate","2024-10-13",{"date":102,"type":37},"2024-10-16",{"date":104,"type":37},"2023-05-01",{"date":106,"type":21},"2026-04-01",{"name":108,"class":44},"Ankara University"]