[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"scrotal-pain\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:scrotal-pain":26},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,44],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":4,"enrollmentInfo":17,"targetDuration":4,"studyType":20,"phases":21,"briefSummary":24,"conditions":25,"keywords":27,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":32,"lastUpdatePostDateStruct":33,"startDateStruct":36,"completionDateStruct":38,"leadSponsor":40,"locationsCount":43},"100595643","phase-1-transcranial-magnetic-stimulation-for-chronic-scrotal-content-pain-100595643",false,"NCT07035119","Transcranial Magnetic Stimulation for Chronic Scrotal Content Pain","Inclusion Criteria:\n\n* Male patients with chronic scrotal pain lasting for 6 or more months.\n* Pain must be present 3 or more days of the week.\n\nExclusion Criteria:\n\n* No new pain medications within the last 30 days.","MALE","18 Years",{"count":18,"type":19},50,"ESTIMATED","INTERVENTIONAL",[22,23],"PHASE1","PHASE2","The purpose of this study is to perform an open label feasibility trial of TMS for the treatment of chronic scrotal content pain.",[26],"Scrotal Pain",[28,29,30],"Scrotal pain","testicular pain","Transcranial magnetic stimulation","NOT_YET_RECRUITING","2026-06-10",{"date":34,"type":35},"2026-06-11","ACTUAL",{"date":37,"type":19},"2026-06-30",{"date":39,"type":19},"2030-04-01",{"name":41,"class":42},"Medical University of South Carolina","OTHER",1,{"id":45,"slug":46,"hasResults":11,"nctId":47,"briefTitle":48,"officialTitle":49,"acronym":4,"eligibilityCriteria":50,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":51,"enrollmentInfo":52,"targetDuration":54,"studyType":55,"phases":4,"briefSummary":56,"conditions":57,"keywords":60,"overallStatus":62,"whyStopped":4,"lastUpdateSubmitDate":63,"lastUpdatePostDateStruct":64,"startDateStruct":66,"completionDateStruct":68,"leadSponsor":70,"locationsCount":43},"100631311","evaluation-of-the-diagnostic-performance-of-the-testicular-workup-for-ischemia-and-suspected-torsion-twist-score-for-assessing-the-risk-of-testicular-torsion-in-adult-patients-presenting-to-the-emergency-department-with-scrotal-pain---a-prospective-observational-study-100631311","NCT07499024","Evaluation of the Diagnostic Performance of the Testicular Workup for Ischemia and Suspected Torsion (TWIST) Score for Assessing the Risk of Testicular Torsion in Adult Patients Presenting to the Emergency Department With Scrotal Pain - A Prospective Observational Study","Evaluation of the Diagnostic Performance of the Testicular Workup for Ischemia and Suspected Torsion (TWIST) Score for Assessing the Risk of Testicular Torsion in Adult Patients Presenting to the Emergency Department With Scrotal Pain","Inclusion Criteria:\n\n* Male patients aged 18-40 years\n\nPresenting to the Emergency Department with acute scrotal pain or scrotal symptoms\n\nSuspicion of testicular torsion before clinical assessment\n\nExclusion Criteria:\n\n* Scrotal pain or symptoms caused by trauma\n\nSymptom duration \\> 1 week\n\nHistory of testicular surgery\n\nInability to provide informed consent (e.g., language barrier or cognitive limitation)","40 Years",{"count":53,"type":19},1000,"30 Days","OBSERVATIONAL","This prospective multicenter observational study aims to evaluate the diagnostic accuracy of the Testicular Workup for Ischemia and Suspected Torsion (TWIST) score in adult patients presenting with acute scrotal pain in Swedish Emergency Departments.\n\nThe TWIST score is a clinical decision tool originally validated in pediatric populations to stratify patients into low, intermediate, and high risk for testicular torsion. The study will include men aged 18-40 years presenting with scrotal pain or symptoms suggestive of torsion. Patients with scrotal trauma, symptom duration over one week, previous testicular surgery, or inability to give informed consent in Swedish will be excluded.\n\nParticipants' clinical findings will be recorded on a standardized form, and the TWIST score will be calculated. Management will follow standard clinical practice independently of the study. Primary outcome is the diagnostic accuracy of the TWIST score to rule out testicular torsion in low-risk patients (TWIST 0-2). Secondary outcomes include diagnosis of torsion within 30 days, time to surgery, patient-reported pain, number of Doppler ultrasounds performed, and the potential reduction in unnecessary imaging.\n\nThe study will be conducted at multiple Swedish sites, including Linköping University Hospital, under oversight by the Swedish Ethical Review Authority (Etikprövningsmyndigheten, decision number 2025-07400-01). The results aim to inform clinical practice by providing a validated decision-support tool for adult patients with suspected testicular torsion, potentially improving patient outcomes and resource utilization.",[58,59,26],"Testicular Torsion","Acute Scrotum",[58,59,61],"Testicular Workup for Ischemia and Suspected Torsion (TWIST)","RECRUITING","2026-04-23",{"date":65,"type":35},"2026-04-29",{"date":67,"type":35},"2026-02-01",{"date":69,"type":19},"2029-12-31",{"name":71,"class":42},"University Hospital, Linkoeping"]