[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"secondary-hypogonadism\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:secondary-hypogonadism":29},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":30,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":39,"lastUpdatePostDateStruct":40,"startDateStruct":43,"completionDateStruct":45,"leadSponsor":47,"locationsCount":4},"100632766","intratesticular-artery-resistive-index-changes-after-varicocelectomy-100632766",false,"NCT07517952","Intratesticular Artery Resistive Index Changes After Varicocelectomy","Evaluation of Changes in Intratesticular Artery Resistive Index Following Varicocelectomy and Their Correlation With Semen Parameters and Testosterone Levels","Inclusion Criteria:\n\n* Infertile male patients with clinically palpable varicocele (Grade I to III).\n\nExclusion Criteria:\n\n* Extremes of age (pediatric or geriatric populations).\n* History of previous scrotal surgery or trauma.\n* Active urogenital infection (e.g., epididymo-orchitis).\n* History of testicular torsion.\n* Any comorbidity that may independently affect testicular vascularity or hemodynamics.","MALE","18 Years","65 Years",{"count":20,"type":21},40,"ESTIMATED","INTERVENTIONAL",[24],"NA","This study aims to evaluate how blood flow inside the testicles changes after surgery to correct a varicocele, and whether these changes correlate with improvements in semen quality and testosterone levels.\n\nVaricocele is a common, treatable cause of male infertility that can negatively affect testicular function by altering blood flow and temperature. While surgery (varicocelectomy) often improves fertility, doctors are continually looking for ways to predict which patients will benefit the most from the procedure. This study uses scrotal color Doppler ultrasound to measure the Intratesticular Artery Resistive Index (RI), which is an indicator of blood flow resistance and microvascular health, before and after surgery.\n\nResearchers will recruit 40 infertile men with clinically palpable varicoceles. Participants will undergo a baseline evaluation that includes a physical exam, semen analysis, a blood test for total testosterone, and a specialized ultrasound to measure the RI under different physical conditions (lying down, standing, and during a Valsalva maneuver\u002Fbearing down).\n\nAll participants will then undergo a microscopic sub-inguinal varicocelectomy, which is the standard microsurgical treatment. Three months after the surgery, participants will return for follow-up testing to repeat the semen analysis, testosterone blood test, and ultrasound.\n\nThe main goal of the study is to determine if pre-operative RI measurements can serve as an early, reliable predictor of surgical success, specifically looking at the recovery of testicular function, sperm parameters, and hormonal levels.",[27,28,29],"Varicocele","Male Infertility","Secondary Hypogonadism",[31,32,33,34,35,36,37],"Varicocelectomy","Resistive Index","Intratesticular Artery","Semen Parameters","Testosterone","Color Doppler Ultrasonography","Microscopic Sub-inguinal Varicocelectomy","NOT_YET_RECRUITING","2026-04-02",{"date":41,"type":42},"2026-04-08","ACTUAL",{"date":44,"type":21},"2026-05",{"date":46,"type":21},"2027-06",{"name":48,"class":49},"Assiut University","OTHER"]