[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"secondary-prevention-of-coronary-heart-disease\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:secondary-prevention-of-coronary-heart-disease":33},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,56],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":40,"overallStatus":43,"whyStopped":4,"lastUpdateSubmitDate":44,"lastUpdatePostDateStruct":45,"startDateStruct":48,"completionDateStruct":50,"leadSponsor":52,"locationsCount":55},"100638424","ecardiacrehab---a-hybrid-patient-centered-ehealth-programme-100638424",false,"NCT07590635","eCardiacRehab - a Hybrid Patient-Centered eHealth Programme","eCardiacRehab - a Randomized Controlled Trial on a Hybrid Home-Based Patient-Centered eHealth Programme With Tailored Solutions","eCardiacRehab","Inclusion Criteria:\n\n* Adult Norwegian (or Scandinavian) speaking patients (≥ 18 years) who have a Norwegian national identification number\n* With coronary artery disease after percutaneous coronary intervention\n* Living at home\n* Have internet available\n* Provide signed informed consent\n\nExclusion Criteria:\n\n* Patients with cognitive impairment that may interfere with the ability to comply with the study protocol\n* Severe aortic stenosis\n* Severe arrhythmias\n* Expected lifetime less than one year as determined by study personnel\n* Otherwise clinically unstable\n* Not fully revascularized\n* Awaits percutaneous coronary intervention or coronary artery bypass graft surgery\n* Inability to comply with the study protocol due to any physical disability, somatic disease, or mental problems as determined by study personnel","ALL","18 Years",{"count":20,"type":21},1000,"ESTIMATED","INTERVENTIONAL",[24],"NA","The overall aim of eCardiacRehab trial is to meet rehabilitation needs of patients with coronary artery disease (CAD) regardless of their access to traditional place-based rehabilitation by developing and evaluating the efficacy and cost effectiveness of an interdisciplinary and comprehensive home-based hybrid programme. eCardiacRehab address patient- and system level challenges to increase access to cardiac rehabilitation (CR). We give particular attention to older patients, women, and those with comorbidities or mental health challenges. The vision of the hybrid home-based eCardiacRehab programme is to make CR available to all.\n\neCardiacRehab is a prospective, multicentre randomized open-label blinded end point evaluation (PROBE) trial. The primary endpoint is a hierarchical composite endpoint using a win-ratio framework combining cardiovascular (CV) death, unplanned contacts to the Emergency Department (ED) for observation or admission (\\>24 hours) for CV disease, and quality of life. Inclusion criteria are adult Scandinavian speaking patients (≥ 18 years) who have a Norwegian national identification number, with CAD treated with Percutaneous Coronary Intervention (PCI), are living at home, and have internet available to them and providing signed informed consent. Exclusion criteria are patients with severe aortic stenosis, severe arrhythmias, expected lifetime less than one year as determined by study personnel, otherwise clinically unstable, not fully revascularized, awaits PCI or coronary artery bypass graft operation (CABG) or inability to comply with the study protocol due to any physical disability, somatic disease, cognitive impairment or mental health challenges as determined by study personnel.",[27,28,29,30,31,32,33,34,35,36,37,38,39],"Comorbidities and Coexisting Conditions","Ethics","Continuity of Patient Care","Older Adults (65 Years and Older)","Cost-Benefit Analysis","Adherence, Medication","Secondary Prevention of Coronary Heart Disease","Health Literacy","eHealth Literacy","Mental Health","Cardiac Rehabilitation","Womens's Health","Coronary Artery Disease (CAD)",[37,41,42],"Coronary Artery Disease","Percutaneous Coronary Intervention","RECRUITING","2026-06-18",{"date":46,"type":47},"2026-06-23","ACTUAL",{"date":49,"type":47},"2026-05-21",{"date":51,"type":21},"2037-12-31",{"name":53,"class":54},"Haukeland University Hospital","OTHER",1,{"id":57,"slug":58,"hasResults":11,"nctId":59,"briefTitle":60,"officialTitle":61,"acronym":4,"eligibilityCriteria":62,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":63,"targetDuration":4,"studyType":22,"phases":65,"briefSummary":66,"conditions":67,"keywords":4,"overallStatus":43,"whyStopped":4,"lastUpdateSubmitDate":68,"lastUpdatePostDateStruct":69,"startDateStruct":71,"completionDateStruct":73,"leadSponsor":75,"locationsCount":55},"100612876","intelligent-management-platform-for-guiding-exercise-rehabilitation-in-coronary-heart-disease-patients-100612876","NCT07259278","Intelligent Management Platform for Guiding Exercise Rehabilitation in Coronary Heart Disease Patients","Artificial Intelligence-enhanced Stratified Management Platform Guiding Home-based Exercise Rehabilitation for Coronary Heart Disease Patients: a Randomized Control Trial","Inclusion Criteria:\n\n* CHD patients aged over 18 years;\n* Stratified as low-risk for cardiovascular events during exercise and classified as low-risk according to the GRACE risk score.\n* Ability of the patient or close relatives to use smartphones and applications;\n* Willingness to participate and sign the informed consent form.\n\nExclusion Criteria:\n\n* Residual stenosis of \\>50% in the left main coronary artery, or \\>70% stenosis in other major epicardial vessels;\n* Planned coronary revascularization within the next 3 months;\n* Acute myocardial infarction within the past 1 month;\n* Severe cognitive impairment;\n* Severely impaired exercise capacity.\n* Advanced-stage malignancy;\n* Life expectancy less than 3 months;\n* Severe multi-organ failure;\n* Other conditions deemed unsuitable for home-based exercise rehabilitation following assessment by a specialist rehabilitation physician.\n* Refusal to provide written informed consent.",{"count":64,"type":21},200,[24],"The goal of this clinical trial is to find out if an artificial intelligence (AI)-enabled stratified management platform can help adults with coronary heart disease (CHD) better perform exercise rehabilitation and manage their health after being discharged from the hospital. The main questions it aims to answer are:\n\n1. Does using the AI platform lead to a greater improvement in exercise capacity (measured by peak oxygen consumption, VO2peak) after 3 months?\n2. Does the platform help increase daily physical activity, improve exercise adherence and motivation, and better control modifiable cardiovascular risk factors?\n3. Is guiding home-based exercise with this platform safe for low-risk CHD patients?\n\nResearchers will compare the AI Management Group (using the platform and a sports wristband) to the Routine Management Group (receiving usual care without the platform) to see if the AI group shows more significant improvements in fitness and health metrics.\n\nParticipants will:\n\n1. Be randomly assigned to either use the AI platform or receive usual post-discharge care.\n2. Receive a personalized exercise prescription from a doctor before going home.\n3. If in the AI group: Use the smartphone app and wearable device to track health data for comprehensive post-discharge management, and receive reminders and immediate safety alerts.\n4. Attend a follow-up visit at 3 months for check-ups and tests, including an exercise test and health assessments.\n\nThe study hopes to show that this intelligent management platform is an effective and safe tool to help people with CHD recover at home, stay active, and reduce future heart risks.",[33],"2025-11-20",{"date":70,"type":47},"2025-12-02",{"date":72,"type":21},"2025-12-01",{"date":74,"type":21},"2026-11-30",{"name":76,"class":77},"China National Center for Cardiovascular Diseases","OTHER_GOV"]