[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"sedation-during-gi-endoscopy\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:sedation-during-gi-endoscopy":25},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,43],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":23,"conditions":24,"keywords":26,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":31,"lastUpdatePostDateStruct":32,"startDateStruct":35,"completionDateStruct":37,"leadSponsor":39,"locationsCount":42},"100640768","tolerability-of-remimazolam-versus-midazolam-in-eus-100640768",false,"NCT07600073","Tolerability of Remimazolam Versus Midazolam in EUS","Tolerability of Sedation With Remimazolam Versus Midazolam in Outpatients Undergoing Upper GI or Biliopancreatic Endoscopic Ultrasound in a Non-Anesthesiologist Setting: A Prospective Observational Study (REM-EUS Study)","REM-EUS","Inclusion Criteria:\n\n* Age \\> 18 years\n* Outpatients undergoing diagnostic EUS (upper GI or biliopancreatic)\n* Informed consent obtained\n\nExclusion Criteria:\n\n* Known allergy to study medications\n* Recent upper respiratory infection or asthma attack\n* History of sedative or opioid addiction\n* Advanced oncologic disease with peritoneal metastases\n* ASA score ≥ IV","ALL","18 Years",{"count":20,"type":21},126,"ESTIMATED","OBSERVATIONAL","This study will observe and compare patient experience during outpatient diagnostic endoscopic ultrasound (EUS) when moderate sedation is provided with either remimazolam plus fentanyl or midazolam plus fentanyl, according to routine clinical practice.\n\nBoth sedation approaches are currently used in standard care. The choice of sedative will be made by the treating physician as part of usual practice and not assigned by the study. The purpose of the study is to evaluate how patients tolerate the procedure with each sedation strategy, focusing on comfort, recovery, and overall procedural experience.\n\nAfter the procedure, participants will be asked to complete questionnaires about their experience at 1 hour and 24 hours after EUS. The study will also collect information on sedation effectiveness, operator satisfaction, recovery time, adverse events, and costs.\n\nThis is a prospective observational single-center study involving adult outpatients undergoing diagnostic EUS. Information collected during routine care, including vital signs, recovery measures, and procedural data, will be analyzed to compare outcomes between the two sedation approaches.",[25],"Sedation During GI Endoscopy",[27,28,29],"Remimazolam","Midazolam","Endoscopic ultrasound","RECRUITING","2026-05-18",{"date":33,"type":34},"2026-05-20","ACTUAL",{"date":36,"type":34},"2026-02-01",{"date":38,"type":21},"2026-08-15",{"name":40,"class":41},"Azienda Socio Sanitaria Territoriale di Lecco","OTHER",1,{"id":44,"slug":45,"hasResults":11,"nctId":46,"briefTitle":47,"officialTitle":48,"acronym":4,"eligibilityCriteria":49,"healthyVolunteers":11,"sex":17,"minAge":50,"maxAge":51,"enrollmentInfo":52,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":54,"conditions":55,"keywords":56,"overallStatus":58,"whyStopped":4,"lastUpdateSubmitDate":59,"lastUpdatePostDateStruct":60,"startDateStruct":62,"completionDateStruct":64,"leadSponsor":66,"locationsCount":4},"100625518","comparison-between-two-drugs-in-sedation-of-upper-gi-endoscopy-100625518","NCT07423676","Comparison Between Two Drugs in Sedation of Upper GI Endoscopy","Ketamine - Dexmedetomidine(Ketodex) Versus Propofol -Midazolam for Sedation in Patients Undergoing Upper Gastrointestinal Endoscopy","Inclusion Criteria\n\n* Patient acceptance\n* Adults aged 21-60 years.\n* Both sexes\n* BMI\\\u003C35 kg\u002Fm2\n* ASA physical status :I\\& II\n* Patients Undergoing Gastrointestinal endoscopy\n* Duration \\\u003C30mintues\n\nExclusion Criteria:\n\n* • Known allergy to any of the study drugs\n\n  * Unstable Cardiovascular disease\n  * Moderate to severe respiratory diseases","21 Years","60 Years",{"count":53,"type":21},52,"The goal of this clinical trial is to compare time of sedation between two drugs administered to patients undergoing upper gastrointestinal endoscopy Primary outcome : Time of sedation : is the time to reach sedation score of 5 according to modified Ramsay sedation score starting from the time of injecting bolts dose of study drugs\n\nSecondary outcome :\n\n* Recovery time :is the time to reach score 2 of modified Ramsay sedation score starting from injecting bolus dose of study drugs .\n* Hemodynamics (MAP,HR) \\& oxygen saturation\n* Drug side effects (nausea,vomitting,agitation)\n* Endoscopist satisfaction",[25],[57],"Sedation","NOT_YET_RECRUITING","2026-02-14",{"date":61,"type":34},"2026-02-20",{"date":63,"type":21},"2026-03-01",{"date":65,"type":21},"2026-05-02",{"name":67,"class":68},"Zagazig University","OTHER_GOV"]