[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"semen-analysis\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:semen-analysis":25},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,48],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":15,"sex":16,"minAge":4,"maxAge":4,"enrollmentInfo":17,"targetDuration":4,"studyType":20,"phases":21,"briefSummary":23,"conditions":24,"keywords":28,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":36,"lastUpdatePostDateStruct":37,"startDateStruct":40,"completionDateStruct":42,"leadSponsor":44,"locationsCount":47},"100600140","evaluating-the-utility-of-implementing-microfluids-for-sperm-preparation-compared-to-conventional-method-of-density-gradient-centrifugation-in-a-pgt-a-program-a-sibling-oocyte-study-100600140",false,"NCT07093619","Evaluating the Utility of Implementing Microfluids for Sperm Preparation Compared to Conventional Method of Density Gradient Centrifugation in a PGT-A Program: a Sibling Oocyte Study","Inclusion Criteria:\n\n1. Women with at least 8 MII per cycle after denudation (AFC≥8).\n2. Women of all ages.\n3. All embryo qualities ≥BL3CC at the time of biopsy on day 5, 6 and\u002For 7.\n4. Fresh sperm used from ejaculate with a concentration ≥1 mill\u002Fml and ≥10% motility (A+B).\n5. Sperm samples with a minimum of 2 ml.\n\nExclusion Criteria:\n\n* Frozen oocytes samples with severe oligospermia (≤1mill\u002Fml).\n* PGT-M cases\n* Sperm with \\> 1M\u002Fml of round cells",true,"ALL",{"count":18,"type":19},100,"ESTIMATED","INTERVENTIONAL",[22],"NA","In assisted reproductive technology (ART), sperm preparation aims to select the most viable sperm for ICSI. Unlike conventional methods like density gradients or sperm washing, microfluidic techniques mimic natural selection in the female reproductive tract by using laminar flow without centrifugation, reducing the risk of DNA damage. This method isolates highly motile sperm while filtering out debris and immotile cells. Studies show that microfluidics improve embryo quality, increase pregnancy rates, and may lead to higher euploidy rates. Additional benefits include improved safety, scalability, and shorter preparation times.",[25,26,27],"Semen Analysis","ICSI","PGT-A",[29,30,31,32,33,34],"IVF","Sperm Preparation","euploid","fertilization rate","blastulation rate","morphokinetics","RECRUITING","2025-09-30",{"date":38,"type":39},"2025-10-02","ACTUAL",{"date":41,"type":39},"2025-09-12",{"date":43,"type":19},"2026-12-30",{"name":45,"class":46},"ART Fertility Clinics LLC","OTHER",1,{"id":49,"slug":50,"hasResults":11,"nctId":51,"briefTitle":52,"officialTitle":53,"acronym":4,"eligibilityCriteria":54,"healthyVolunteers":11,"sex":55,"minAge":56,"maxAge":57,"enrollmentInfo":58,"targetDuration":60,"studyType":61,"phases":4,"briefSummary":62,"conditions":63,"keywords":66,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":71,"lastUpdatePostDateStruct":72,"startDateStruct":74,"completionDateStruct":76,"leadSponsor":78,"locationsCount":47},"100561231","testicular-function-and-semen-quality-in-male-childhood-and-adolescent-cancer-survivors-100561231","NCT06587477","Testicular Function and Semen Quality in Male Childhood and Adolescent Cancer Survivors","Effect of Cancer Treatment on Testicular Function and Semen Quality in Male Childhood and Adolescent Cancer Survivors","Inclusion Criteria:\n\n* Men who have received chemotherapy and\u002F or radiotherapy for cancer diagnosed when they were \\\u003C 18 years old.\n* \\> 18 years old to 50 years old\n* Cancer in remission for at least 2 years\n\nExclusion Criteria:\n\n* Unable to ejaculate by masturbation to provide semen samples\n* Cryptorchidism, testicular cancer, history of vasectomy\n* On testosterone replacement therapy\n* Refusal to join the study","MALE","18 Years","50 Years",{"count":59,"type":19},200,"3 Weeks","OBSERVATIONAL","Cancer treatment can affect the testicular function, including sperm and hormonal functions. The aim of this study is to assess the testicular function and semen quality in young men who recover from childhood and adolescent cancer in Hong Kong. This can provide more information for pre-treatment counselling as well as improve post treatment survivorship care. The testicular function will be compared to aged-matched controls from men attending the Family Planning Association for premarital check-up.",[64,65,25],"Cancer, Treatment-Related","Late Effect",[67,68,69,70],"cancer treatment","testicular function","semen quality","cancer survivors","2024-09-06",{"date":73,"type":39},"2024-09-19",{"date":75,"type":39},"2023-01-16",{"date":77,"type":19},"2028-06-30",{"name":79,"class":46},"The University of Hong Kong"]