[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"sensory-impairments\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:sensory-impairments":25},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,46],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":4,"briefSummary":22,"conditions":23,"keywords":28,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":34,"lastUpdatePostDateStruct":35,"startDateStruct":38,"completionDateStruct":40,"leadSponsor":42,"locationsCount":45},"100597961","plantar-sensation-position-sense-and-weight-bearing-asymmetry-related-to-balance-and-mobility-post-stroke-100597961",false,"NCT07065292","Plantar Sensation, Position Sense, and Weight-Bearing Asymmetry Related to Balance and Mobility Post-Stroke","Investigation of the Relationship Between Plantar Sensation, Lower Extremity Position Sense, and Weight-Bearing Asymmetry With Posture, Balance, and Mobility in Individuals With Chronic Stroke","Inclusion Criteria:\n\n* Diagnosis of stroke confirmed by a physician (via official report)\n* Minimum of 6 months since stroke onset\n* Aged 18 years or older\n* Mini-Mental State Examination score ≥ 20\n* Brunnstrom lower extremity stage ≥ 3\n* Ability to complete assessments with or without walking aids\n* Voluntary participation\n\nExclusion Criteria:\n\n* Additional neurological, metabolic, or orthopedic conditions\n* Severe vision or hearing impairments\n* Modified Ashworth Score of 4 in any lower limb muscle","ALL","18 Years",{"count":19,"type":20},22,"ESTIMATED","OBSERVATIONAL","This study aims to examine how sensory deficits and weight-bearing asymmetry affect posture, balance, and mobility in individuals with chronic stroke. The research focuses on evaluating the relationships between plantar foot sensation, lower extremity position sense, and asymmetrical weight distribution with functional abilities such as walking and postural control.\n\nParticipants will undergo non-invasive assessments, including sensation tests, mobility and balance evaluations, and postural measurements. A total of 24 individuals with chronic stroke who are receiving physiotherapy at a rehabilitation center in Konya, Türkiye, will be included.\n\nThe results of this observational, cross-sectional study may contribute to a better understanding of the sensory-motor interactions in stroke survivors and support the development of more targeted rehabilitation strategies.",[24,25,26,27],"Chronic Stroke","Sensory Impairments","Postural Control","Balance",[24,29,30,31,32],"Somatosensory Function","Plantar Sensation","Balance Assessment","Weight-Bearing Asymmetry","RECRUITING","2025-07-03",{"date":36,"type":37},"2025-07-15","ACTUAL",{"date":39,"type":37},"2025-05-20",{"date":41,"type":20},"2026-01-20",{"name":43,"class":44},"Afyonkarahisar Health Sciences University","OTHER",1,{"id":47,"slug":48,"hasResults":11,"nctId":49,"briefTitle":50,"officialTitle":51,"acronym":52,"eligibilityCriteria":53,"healthyVolunteers":11,"sex":16,"minAge":54,"maxAge":4,"enrollmentInfo":55,"targetDuration":57,"studyType":21,"phases":4,"briefSummary":58,"conditions":59,"keywords":62,"overallStatus":66,"whyStopped":4,"lastUpdateSubmitDate":67,"lastUpdatePostDateStruct":68,"startDateStruct":70,"completionDateStruct":72,"leadSponsor":74,"locationsCount":4},"100576262","development-of-an-ensemble-learning-based-multi-dimensional-sensory-impairment-score-to-predict-cognitive-impairment-in-an-elderly-cohort-of-southern-italy-100576262","NCT06783010","Development of an Ensemble Learning-based, Multi-dimensional Sensory Impairment Score to Predict Cognitive Impairment in an Elderly Cohort of Southern Italy","Sviluppo di Uno Score di Rischio Multidimensionale Basato Sui Deficit Sensoriali, Con un Approccio in Ensemble Learning, Per il Deterioramento Cognitivo in Una Coorte di Anziani Dell'Italia Meridionale","DEMETRA","Cases: The cases included will be on two different stages of cognitive impairment: MCI and dementia.\n\nThe inclusion criteria for the MCI cases group will be: 1) to be at least 65 years old at the moment of enrollment: 2) to have an MCI (Montreal Cognitive Assessment, MOCA test, between 15.5-26) 3) to have a complete examination of the clinical, neuropsychological and sensory evaluations. The exclusion criteria for the case group will be 1) do not have the mental capacity to express consent at the follow-up; 2) have developed major malignancies or undergo major therapies could cause a loss in sensory function or cognitive decline; 3) be diagnosed with depression. The total number of MCI cases will be 45.\n\nThe inclusion criteria for the dementia cases group will be: 1) to be at least 65 years old at the moment of enrollment: 2) to have a mild to moderate cognitive impairment (Montreal Cognitive Assessment, MOCA test, below 15.5) to have a complete examination of the clinical, neuropsychological and sensory evaluations. The exclusion criteria for the case group will be 1) do not have the mental capacity to express consent at the follow-up; 2) have developed major malignancies or undergo major therapies could cause a loss in sensory function or cognitive impairment; 3) be diagnosed with depression. The total number of dementia cases will be 22 (among all the study sites).\n\nControl Cohort: The inclusion criteria for the control cohort group will be: 1) to be at least 65 years old at the moment of enrollment: 2) to have a complete examination of the clinical, neuropsychological and sensory evaluations 3) to have no cognitive impairment (measured using MOCA greater 26). The total number of controls will be at least 151 (considering 1:5 allocation).","65 Years",{"count":56,"type":20},30,"2 Years","There is now strong scientific literature showing a relationship between sensory loss and cognitive performance and between sensory loss and incident dementia. We take as our starting point that people with hearing, vision, and\u002For cognitive problems have poorer health outcomes, possibly due to due to common age-related mechanism(s), iatrogenic problems in the health care system (e.g., misdiagnosis), and\u002For the decay of social networks. With this evidence, our project will provide a better understanding of the relationship between sensory loss and cognitive loss in older adults with or at risk for dementia using objective technologies to measure sensory deficits that refer not only to vision loss, hearing loss, olfaction and taste but also to senses deemed atypical, i.e., nociception. In particular, the project aims:\n\n1. To assess the specific association between different sensory measures (central and peripheral hearing loss, retinal abnormalities measured by OCT, smell and taste objective measures, chronic pain, and proprioception subjective and electrophysiological measures.\n2. To develop a multi-dimensional score using sensory features and clinical and lifestyle variables to predict the different types of dementia (Alzheimer's Disease, Fronto-Temporal Dementia, and Vascular Dementia) at different stages (Mild Cognitive impairment and Normal Cognition).\n3. To create a connectomic map of the MRI morphologic and dynamic features of the Dementia cases and their relationships with sensorial features, describing the patterns differences in respect to the normal cognition controls.\n\nTo achieve the proposed aims, the synergic work of the four units involved in the proposal will be required. Subject assessment will be divided between clinical setting (ICS Maugeri) and population setting (ASL BARI). IRCCS \"S. De Bellis\" will provide expertise for both design refinement, creation and monitoring of deliverables and milestones, and technological support for sense measurements. Finally, the features extracted in clinical populations afferent to the centers of the Azienda Sanitaria Locale di Bari and the neurological clinics of the ICS Maugeri will be analyzed with innovative methods by the Polytechnic University of Bari using artificial intelligence algorithms based on ensemble learning for the creation of a predictive score for cognitive impairment that takes into account both sensory and clinical aspects and related to lifestyles.",[25,60,61],"Cognitive Impairment","Artificial Intelligence",[63,64,65],"artificial intelligence","sensory impairments","cognitive impairments","NOT_YET_RECRUITING","2025-01-14",{"date":69,"type":37},"2025-01-20",{"date":71,"type":20},"2025-06-30",{"date":73,"type":20},"2026-01-10",{"name":75,"class":44},"Azienda Sanitaria Locale Bari"]