[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"sepsis-bacteremia\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:sepsis-bacteremia":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":4,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":33,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":39,"lastUpdatePostDateStruct":40,"startDateStruct":43,"completionDateStruct":45,"leadSponsor":47,"locationsCount":50},"100514221","reducing-empiric-vancomycin-use-in-pediatric-suspected-sepsis-100514221",false,"NCT05975671","Reducing Empiric VAncomycin Use in Pediatric Suspected Sepsis","Reducing Empiric VAncomycin Use in Pediatric Suspected Sepsis (REVAMP-Sepsis)","REVAMP","Patient Inclusion Criteria:\n\n* Admitted to one of the participating PICUs during the study period\n\nPatient Exclusion Criteria:\n\n* None\n\nClinician Inclusion Criteria:\n\n1. PICU prescribing clinician (including attending physicians, fellows, residents, nurse practitioners, and physician assistants) OR sepsis stakeholder (leader of sepsis quality improvement work, medical director) at one of the participating sites at the time the survey is deployed\n2. Age ≥ 18 years old\n3. Employed by one of the participating sites\n\nClinician Exclusion Criteria:\n\n1. Volunteers or other non-employee hospital staff\n2. Limited English proficiency","ALL",{"count":19,"type":20},52500,"ESTIMATED","INTERVENTIONAL",[23],"NA","The goal of this quasi-experimental interventional study is to determine the effectiveness of a multifaceted stewardship intervention in reducing overall vancomycin use in five tertiary care Pediatric Intensive Care Units (PICU).\n\nThere are two groups of subjects in this study: PICU clinicians\u002Fsepsis stakeholders and patients admitted to one of the participating PICUs during the study period. The intervention will at a minimum include:\n\n* Implementation of a clinical guideline indicating when vancomycin should and should not be used\n* Unit-level feedback on overall vancomycin use within and across centers\n* Clinician education.",[26,27,28,29,30,31,32],"Sepsis","Sepsis Mrsa","Sepsis Bacteremia","Antimicrobial - Induced Nephropathy","Sepsis, Severe","Septic Shock","Septic Syndrome",[26,34,35,36,37],"Vancomycin use","methicillin-resistant Staphylococcus aureus (MRSA)","Antibiotic Stewardship","Implementation science","RECRUITING","2025-09-17",{"date":41,"type":42},"2025-09-19","ACTUAL",{"date":44,"type":42},"2023-08-21",{"date":46,"type":20},"2026-05",{"name":48,"class":49},"Children's Hospital of Philadelphia","OTHER",4]