[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"severe-tricuspid-regurgitation\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:severe-tricuspid-regurgitation":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,50],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":28,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":39,"lastUpdatePostDateStruct":40,"startDateStruct":43,"completionDateStruct":45,"leadSponsor":47,"locationsCount":4},"100617690","transcatheter-tricuspid-valve-replacement-with-the-medtronic-intrepid-transcatheter-tricuspid-valve-replacement-ttvr-system-in-severe-tricuspid-regurgitation-100617690",false,"NCT07321899","Transcatheter Tricuspid Valve Replacement With the Medtronic Intrepid™ Transcatheter Tricuspid Valve Replacement (TTVR) System in Severe Tricuspid Regurgitation","Transcatheter Tricuspid Valve Replacement Using the Medtronic Intrepid™ TTVR System in Patients With Severe Symptomatic Tricuspid Regurgitation - PATHFINDER","PATHFINDER","Inclusion Criteria:\n\n* Age ≥18 years at the time of consent.\n* Severe symptomatic tricuspid regurgitation (TR) despite optimal medical therapy (OMT).\n* Local site multidisciplinary heart team experienced in tricuspid valve therapies agrees that the subject is appropriate for TTVR.\n\nExclusion Criteria:\n\n* Any tricuspid device currently in place.\n* Anatomic contraindications.\n* Need for emergent or urgent surgery.\n* Left ventricular ejection fraction \\\u003C25%.","ALL","18 Years",{"count":20,"type":21},1186,"ESTIMATED","INTERVENTIONAL",[24],"NA","This clinical trial evaluates the safety and effectiveness of the Medtronic Intrepid™ Transcatheter Tricuspid Valve Replacement (TTVR) System in symptomatic patients with severe or greater tricuspid regurgitation.",[27],"Severe Tricuspid Regurgitation",[29,30,31,32,33,34,35,36,37],"Tricuspid Regurgitation","Symptomatic tricuspid regurgitation","Heart valve disease","Structural heart intervention","Severe valve disease","Randomized controlled trial","tricuspid insufficiency","tricuspid disease","tricuspid valve disease","NOT_YET_RECRUITING","2026-01-06",{"date":41,"type":42},"2026-01-08","ACTUAL",{"date":44,"type":21},"2026-06",{"date":46,"type":21},"2041-04",{"name":48,"class":49},"Medtronic Cardiovascular","INDUSTRY",{"id":51,"slug":52,"hasResults":11,"nctId":53,"briefTitle":54,"officialTitle":54,"acronym":55,"eligibilityCriteria":56,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":57,"enrollmentInfo":58,"targetDuration":60,"studyType":61,"phases":4,"briefSummary":62,"conditions":63,"keywords":64,"overallStatus":68,"whyStopped":4,"lastUpdateSubmitDate":69,"lastUpdatePostDateStruct":70,"startDateStruct":72,"completionDateStruct":74,"leadSponsor":76,"locationsCount":79},"100317708","international-multisite-transcatheter-tricuspid-valve-therapies-registry-100317708","NCT03416166","International Multisite Transcatheter Tricuspid Valve Therapies Registry","TriValve","Inclusion Criteria:\n\n* All the patients undergoing transcatheter tricuspid valve intervention.\n\nGeneral inclusion criteria:\n\n* Minimal age: 18 years\n* Patient is able to give written informed consent to the procedure\n\nExclusion Criteria:\n\n* Patients not fulfilling the indications for transcatheter tricuspid intervention","99 Years",{"count":59,"type":21},269,"10 Years","OBSERVATIONAL","For a long time, tricuspid valve disease has been considered as less important than left-sided valvular heart disease. If treated in an advanced stage and simultaneously with other cardiac diseases, it is associated with significant morbidity and mortality. Hence, physicians tend to refer patients more aggressively to surgery (1).\n\nTranscatheter procedures are an attractive alternative in high-risk patients. The field of transcatheter tricuspid devices has rapidly advanced over the last few years (2). Limited knowledge is available regarding the epidemiologic and anatomical settings in which these therapies are preferentially applied.\n\nThe main purpose of this registry is the collection of baseline clinical and anatomical data of the patients treated with transcatheter tricuspid valve therapies, and their outcomes, whenever feasible. Apart from more knowledge regarding the current status in this field, the results could also help the establishment of guidelines with respect to the choice of the transcatheter device selected and to understand which therapy can provide the better outcome in the different anatomies. Moreover, this study will provide important information about the epidemiology of severe tricuspid regurgitation, which is at the moment an undertreated disease.",[27],[65,66,67],"Tricuspid Valve","tricuspid regurgitation","transcatheter tricuspid regurgitation","RECRUITING","2018-01-29",{"date":71,"type":42},"2018-01-30",{"date":73,"type":42},"2016-11-01",{"date":75,"type":21},"2026-11-01",{"name":77,"class":78},"University of Zurich","OTHER",1]