[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"sexual-behavior\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:sexual-behavior":32},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,15,0,[8,57,96,121,151,180,204,242,267,300,330,372,401,423,452],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":20,"enrollmentInfo":21,"targetDuration":4,"studyType":24,"phases":25,"briefSummary":27,"conditions":28,"keywords":33,"overallStatus":44,"whyStopped":4,"lastUpdateSubmitDate":45,"lastUpdatePostDateStruct":46,"startDateStruct":49,"completionDateStruct":51,"leadSponsor":53,"locationsCount":56},"100645303","transcendenthealth-a-text-messaging-pregnancy-prevention-program-for-transgender-boys-100645303",false,"NCT07681908","#TranscendentHealth: A Text Messaging Pregnancy Prevention Program for Transgender Boys","#TranscendentHealth - Adapting an LGB+ Inclusive Teen Pregnancy Prevention Program for Transgender Boys","THPP","Inclusion Criteria:\n\n* Assigned female sex at birth\n* Does not have an exclusively cisgender gender identity (e.g., identifies as transgender boy, nonbinary, gender fluid, or unsure of gender identity)\n* Age 14 to 18 years and has not yet graduated from high school\n* Exclusive owner of a cell phone with an unlimited text messaging plan\n* Has access to the Internet to complete online surveys\n* Plans to keep the same cell phone number for at least the next 6 months\n* Able to provide informed assent (ages 14-17) or consent (age 18), including the capacity to do so\n* Has not participated in a prior #TranscendentHealth study activity and does not know anyone currently enrolled in the study\n\nExclusion Criteria:\n\n* Has graduated from high school\n* Has participated in a prior #TranscendentHealth study activity (focus groups, Content Advisory Teams, or beta test)\n* Knows another person currently enrolled in the study",true,"FEMALE","14 Years","18 Years",{"count":22,"type":23},467,"ESTIMATED","INTERVENTIONAL",[26],"NA","Transgender and gender-diverse young people who were assigned female at birth (AFAB), including transgender boys, nonbinary youth, and others, face real sexual health disparities. Existing pregnancy and HIV prevention programs are designed for cisgender girls and do not meet the needs of AFAB trans youth, leaving this group without programs that speak to their lives.\n\n#TranscendentHealth is a text messaging sexual health program developed specifically for AFAB transgender and gender-diverse youth ages 14 to 18. It builds on Girl2Girl, a program shown to improve sexual health behaviors in LGB+ cisgender girls, and updates the content to reflect the identities, relationships, and health needs of AFAB trans youth.\n\nThe study has two parts. In the first part, AFAB trans youth help shape the program through focus groups, Content Advisory Teams (youth review panels that give feedback on program messages), and a small pilot test. In the second part, a national randomized controlled trial enrolls 467 AFAB transgender youth ages 14 to 18 across the United States. Participants are randomly assigned to receive either #TranscendentHealth or a general sexual health text messaging program. Both programs are delivered entirely by text message over 5 months, with no in-person visits required. Youth complete short online surveys at the start of the program, at program end (5 months), and at 3 and 6 months after the program ends.\n\nThe study's main goals are to determine whether #TranscendentHealth improves rates of condom-protected sex, use of other birth control methods (such as the pill, shot, or IUD), and HIV\u002FSTI testing. Secondary goals include reducing unintended pregnancy, increasing PrEP uptake among eligible participants, and improving intentions to use sexual health services.",[29,30,31,32],"Pregnancy (Unwanted)","Sexually Transmitted Disease (STD)","HIV Infection","Sexual Behavior",[34,35,36,37,38,39,40,41,42,43],"transgender youth","Nonbinary youth","Assigned female at birth (AFAB)","Pregnancy prevention","Text messaging","mHealth","Sexual health","Gender minority youth","HIV prevention","Contraception","NOT_YET_RECRUITING","2026-07-01",{"date":47,"type":48},"2026-07-02","ACTUAL",{"date":50,"type":23},"2026-06-30",{"date":52,"type":23},"2028-06-30",{"name":54,"class":55},"Center for Innovative Public Health Research","OTHER",1,{"id":58,"slug":59,"hasResults":11,"nctId":60,"briefTitle":61,"officialTitle":62,"acronym":4,"eligibilityCriteria":63,"healthyVolunteers":17,"sex":18,"minAge":20,"maxAge":64,"enrollmentInfo":65,"targetDuration":4,"studyType":24,"phases":67,"briefSummary":68,"conditions":69,"keywords":76,"overallStatus":86,"whyStopped":4,"lastUpdateSubmitDate":87,"lastUpdatePostDateStruct":88,"startDateStruct":90,"completionDateStruct":92,"leadSponsor":94,"locationsCount":56},"100635054","carrii-native-intervention-optimization-trial-100635054","NCT07547696","CARRII Native Intervention Optimization Trial","CARRII Native Intervention Optimization Trial 3-month Factorial Experiment With 512 Participants Randomized to 8 Conditions","Inclusion Criteria:\n\n* Native American\u002FAmerican Indian\u002FAlaska Native,\n* who are not surgically sterile,\n* who report alcohol consumption at risk levels and risk for pregnancy in the past 90 days due to having sex with a man with inconsistent, ineffective, or no contraception.\n* Participants must have access to the Internet via a mobile device they can access daily\n\nExclusion Criteria:\n\n* cognitive disorders including mental retardation, dementia, or psychotic disorders that could impair ability to understand the intervention material or give informed consent.","44 Years",{"count":66,"type":23},512,[26],"The purpose of this study is to identify the best combination of new intervention components to use with CARRII, the first automated online intervention for alcohol-exposed pregnancies (AEP). This intervention is specifically designed for Native women and others who can become pregnant. Our goal is to maximize the effectiveness of the online intervention while keeping costs manageable for Native communities.",[70,71,72,73,74,75,32],"Fetal Alcohol Spectrum Disorders","Pregnancy","Alcohol-Related Disorders","Drinking, Alcohol","Contraception Behavior","Alcohol Exposed Pregnancy",[77,78,79,80,81,82,83,84,85],"Native American","female","adult","contraception","alcohol","digital intervention","mobile health (mHealth)","optimization","risk reduction","RECRUITING","2026-06-18",{"date":89,"type":48},"2026-06-23",{"date":91,"type":48},"2026-06-02",{"date":93,"type":23},"2028-07-30",{"name":95,"class":55},"University of Virginia",{"id":97,"slug":98,"hasResults":11,"nctId":99,"briefTitle":100,"officialTitle":101,"acronym":4,"eligibilityCriteria":102,"healthyVolunteers":17,"sex":103,"minAge":20,"maxAge":104,"enrollmentInfo":105,"targetDuration":4,"studyType":24,"phases":107,"briefSummary":108,"conditions":109,"keywords":4,"overallStatus":44,"whyStopped":4,"lastUpdateSubmitDate":111,"lastUpdatePostDateStruct":112,"startDateStruct":114,"completionDateStruct":116,"leadSponsor":118,"locationsCount":120},"100440177","integrative-alcohol-and-risky-sex-feedback-for-college-students-100440177","NCT05011903","Integrative Alcohol and Risky Sex Feedback for College Students","Cross-Tailoring Integrative Alcohol and Risky Sex Feedback for College Students: A Hybrid Type 1 Effectiveness-Implementation Trial","Inclusion Criteria:\n\n* status as first-year college student at University of Kentucky or UNT-Denton\n* 18-20 years old\n\nExclusion Criteria:\n\n* the inability or unwillingness to give informed, voluntary consent to participate\n* not meeting inclusion criteria\n* currently in treatment to reduce alcohol or other substance use\n* pregnant or planning to become pregnant","ALL","20 Years",{"count":106,"type":23},600,[26],"Alcohol misuse and related risky sexual behaviors are significant health concerns for college students. Two-thirds of students are current drinkers, at least 1 in 3 report past month heavy episodic drinking (5+ drinks in a row), and 1 in 10 report high intensity drinking (10+ drinks in a row). Increased student alcohol use and heavy drinking are linked to increased sexual activity and related risky behaviors (e.g., unprotected sex, sex with casual partners). This puts students at risk for negative health outcomes (e.g., STIs - sexually transmitted infections) and is also a pathway to sexual victimization and escalated drinking. The first few weeks of college, known as the 'red zone,' provide an opportunity to intervene at time when these behaviors increase. However, most prevention programs for college students tend to focus on student alcohol use and have little to no integration of content on the relationship between alcohol use and risky sexual behaviors. This is an important gap in the literature and a priority area for NIAAA. The research team established the short-term efficacy of a personalized feedback intervention (PFI), a gold standard intervention approach, with integrated content on alcohol and risky sexual behaviors. In this study, we propose to extend our integrated PFI to include a cross-tailored dynamic feedback (CDF) component. The CDF component will use technology to incorporate daily assessments of student behavior and provide students with dynamic weekly feedback over 12 weeks. The goal is to increase the effectiveness of the integrated PFI and to create a program that is easily implemented on college campuses.",[110,32],"Alcohol Drinking in College","2026-06-10",{"date":113,"type":48},"2026-06-12",{"date":115,"type":23},"2026-07",{"date":117,"type":23},"2027-01-31",{"name":119,"class":55},"Anne E Ray",2,{"id":122,"slug":123,"hasResults":11,"nctId":124,"briefTitle":125,"officialTitle":126,"acronym":127,"eligibilityCriteria":128,"healthyVolunteers":17,"sex":103,"minAge":129,"maxAge":4,"enrollmentInfo":130,"targetDuration":4,"studyType":24,"phases":132,"briefSummary":133,"conditions":134,"keywords":137,"overallStatus":86,"whyStopped":4,"lastUpdateSubmitDate":142,"lastUpdatePostDateStruct":143,"startDateStruct":145,"completionDateStruct":147,"leadSponsor":149,"locationsCount":56},"100536560","imara-for-black-male-caregivers-and-girls-empowerment-image-100536560","NCT06266416","IMARA for Black Male Caregivers and Girls Empowerment (IMAGE)","A Family-Based HIV Prevention Program for Black Men to Protect Black Girls","IMAGE","Inclusion Criteria:\n\nAIM 1:\n\n* Self-identify as African American, Black, or mixed race with African American or Black\n* Speak English\n* Males must identify as a current caregiver to girl enrolled in the study\n\nAIM 2: All Community Based Organizations (CBO) directors and IMAGE liaisons will be eligible.\n\nExclusion Criteria:\n\nAIM 1:\n\n* Girl refuses to participate\n* Inability to understand the consent\u002Fassent process\n* Non-English speaking\n* Does not self-identify as African American, Black, or mixed race with African American or Black\n* If the primary caregiver (female caregiver\u002Fmother) does not consent to the girls' participation with the male caregiver the girl chooses, the girl will not be able to participate\n* Girls will be excluded if they participated in other phases of the research\n\nAIM 2:\n\n• Inability to understand the consent process, and non-employment at a partnering CBO.","13 Years",{"count":131,"type":23},612,[26],"The scientific premise of this research is that individual, interpersonal, and structural factors impact Black girls' sexual reproductive health outcomes (sexually transmitted infection (STI) and Human Immunodeficiency Virus (HIV)) and experience of sexual violence. This study expands STI\u002FHIV prevention programs to include Black male caregivers, a potentially valuable yet underutilized resource to protect Black girls and reduce their exposure to STI\u002FHIV and sexual violence.",[135,136,32],"Sexually Transmitted Infections (Not HIV or Hepatitis)","HIV Infections",[138,139,140,141],"Sexual Health","HIV Prevention","Community Based","Sexually Transmitted Infections","2026-04-13",{"date":144,"type":48},"2026-04-17",{"date":146,"type":48},"2024-09-02",{"date":148,"type":23},"2028-05-31",{"name":150,"class":55},"University of Illinois at Chicago",{"id":152,"slug":153,"hasResults":11,"nctId":154,"briefTitle":155,"officialTitle":156,"acronym":4,"eligibilityCriteria":157,"healthyVolunteers":11,"sex":103,"minAge":19,"maxAge":158,"enrollmentInfo":159,"targetDuration":4,"studyType":24,"phases":161,"briefSummary":162,"conditions":163,"keywords":167,"overallStatus":44,"whyStopped":4,"lastUpdateSubmitDate":172,"lastUpdatePostDateStruct":173,"startDateStruct":174,"completionDateStruct":176,"leadSponsor":178,"locationsCount":4},"100633368","evaluating-whatsok-helpline-for-youth-with-concerns-about-sexual-thoughts-and-behaviors-100633368","NCT07525778","Evaluating WhatsOK Helpline for Youth With Concerns About Sexual Thoughts and Behaviors","A Randomized Control Trial Evaluation of WhatsOK for the Primary Prevention of Problematic Sexual Behaviors Among Youth","Inclusion Criteria:\n\n* must be ages 14-17 years at baseline\n* must have concerns about their sexual thoughts or behaviors\n* must be able to read, write, and speak in English\n\nExclusion Criteria:\n\n* Under 14 or over 17 years of age\n* Does not have concerns about their sexual thoughts or behaviors\n* Previously contacted a helpline or hotline for concerns about their sexual thoughts or behaviors\n* Is not able to read, write, or speak in English\n* Does not consent to participate","17 Years",{"count":160,"type":23},920,[26],"Research suggests up to 77% of harmful sexual experiences during childhood are caused by other youth. Sometimes called peer-peer abuse or youth-perpetrated child sexual abuse, problematic and harmful sexual behavior among youth (PHSBY) involves sexual behaviors that are not developmentally appropriate and have potential to cause harm to the child or children involved.\n\nCompared to adults, children and adolescents who engage in sexual exploration are at greater risk of making mistakes or causing harm, in large part because they have insufficient information about healthy sexual behavior and development, consent, and related concepts. However, the available support, information, and resources for youth who have engaged in or are at risk of engaging in PSHB are limited.\n\nTo address these unmet needs, Stop it Now! (stopitnow.org) created the first youth-focused website and helpline services (WhatsOK) for young people with concerns about their sexual thoughts, interests, and behaviors. WhatsOK.org is a microsite developed specifically for youth aged 14-21 years. If a child or young person has concerns about their sexual thoughts or behaviors, the WhatsOK Online Help Center and Helpline can provide support and resources to support healthy behavior and prevent problematic or harmful behavior. If someone has already engaged in PHSBY or if they are unsure about whether what has been done is illegal, they can still reach out for confidential help to learn about taking steps to stop.\n\nPreliminary findings from a longitudinal, observational study of the WhatsOK helpline suggest that youth are willing to seek out help for their (and others') sexual interests and behaviors, highlighting the critical need for prevention strategies targeting youth with potentially concerning sexual behaviors. We examined the characteristics of contacts to the WhatsOK helpline via data collected from pre-set questions on age, primary reason for contact, timing of inquiry relative to other help-seeking, and timing relative to harm caused. Most inquiries came from youth aged 14 to 21 (57.7%) via email (54.4%). Over half (54.6%) had already engaged in harmful or illegal behaviors or were potentially at risk to do so. The majority of contacts sought help prior to seeking out other external professional resources (54%).\n\nThe current study is a randomized control trial evaluating the impact of the WhatsOK helpline in reducing PHSBY and improving help-seeking attitudes and behavior in a sample of participants ages 14-17 with concerns about their sexual thoughts and behaviors.",[164,165,166,32],"Mental Health","Social Support","Perceived Self-efficacy",[168,169,170,171],"youth sexual behavior","adolescents","support services","helpline","2026-04-07",{"date":142,"type":48},{"date":175,"type":23},"2026-04-06",{"date":177,"type":23},"2029-09-29",{"name":179,"class":55},"Center for Violence Prevention Research Inc",{"id":181,"slug":182,"hasResults":11,"nctId":183,"briefTitle":184,"officialTitle":185,"acronym":4,"eligibilityCriteria":186,"healthyVolunteers":11,"sex":18,"minAge":187,"maxAge":188,"enrollmentInfo":189,"targetDuration":4,"studyType":24,"phases":191,"briefSummary":192,"conditions":193,"keywords":4,"overallStatus":86,"whyStopped":4,"lastUpdateSubmitDate":195,"lastUpdatePostDateStruct":196,"startDateStruct":198,"completionDateStruct":200,"leadSponsor":202,"locationsCount":120},"100567582","rigorous-evaluation-of-lets-talk-birth-control-100567582","NCT06670066","Rigorous Evaluation of Let's Talk Birth Control","Rigorous Evaluation of Let's Talk Birth Control Among Adolescents Attending Community Health Centers","Inclusion Criteria:\n\nHealth Centers:\n\n* Serve 400+ patients assigned female at birth (AFAB) aged 15-24 receiving sexual and reproductive health (SRH) services or general wellness exams annually. Although the project team may enroll rural health centers with smaller populations\n* Have not implemented an adolescent SRH patient-centered training recently\n* Do not utilize a contraceptive decision aid (CDA) designed for adolescent patients\n\nParticipants:\n\n* Assigned female at birth\n* Seeking sexual and reproductive services or general wellness exams at an enrolled community health center\n* Have had penile-vaginal sex in the past year or are interested in discussing birth control with their provider\n* Agree to be in study\n\nExclusion Criteria:\n\nHealth Centers\n\n* Does not serve at least 400 AFAB aged 15-24 receiving SRH services or general wellness exams annually\n* Has recently implemented an adolescent SRH training\n* Currently using a CDA designed for adolescent patients\n\nParticipants:\n\n* Does not agree to be in study\n* Is pregnant or is trying to become pregnant\n* Does not have access to a phone to receive text messages\n* Does not speak English or Spanish","15 Years","24 Years",{"count":190,"type":23},1500,[26],"The goal of this cluster-level randomized controlled trial is to evaluate the impacts of Let's Talk Birth Control, a clinical decision support intervention for adolescents that consists of a printed contraceptive decision aid (CDA), contraceptive counseling, and a QR code to the Bedsider.org Method Explorer (ME). The goal of Let's Talk Birth Control is to reduce rates of sex without a contraceptive method among adolescent patients, increase use of preferred contraceptive method, as well as to increase self-efficacy to discuss, obtain, and correctly use contraceptive methods\n\nThe primary research questions are:\n\n* Does receiving care from a health center participating in Let's Talk Birth Control reduce rates of sex without a contraceptive method among adolescent patients compared to those visiting a standard of care control health center?\n* Does receiving care from a health center participating in Let's Talk Birth Control increase use of preferred contraceptive method among adolescent patients compared to those visiting a standard of care control health center?\n\nThe evaluation will focus on the impacts of receiving the Let's Talk Birth Control intervention, as compared to receiving standard health care services.\n\nAs part of this study:\n\n* All participants will be asked to complete baseline, 1-week post-intervention, and 9-month follow-up surveys.\n* Participants at health centers randomized to receive the Let's Talk intervention, will be asked to:\n* Review the Let's Talk CDA independently prior to meeting with their healthcare provider\n* Participate in an observation focused on the provider's use of the CDA for contraceptive counseling during the healthcare visit (select participants only)\n* Participate in a focus group discussing their perceptions of the Let's Talk Birth Control intervention (select participants only)\n\nStaff at health centers randomized to receive the Let's Talk intervention will be asked to:\n\n* Complete a 45-60 minute online asynchronous training covering patient-centered contraceptive counseling (PCCC) for adolescents and using the CDA\n* Use the Let's Talk CDA to facilitate patient-centered contraceptive counseling with patients that have enrolled in the study",[32,194],"Adolescent Behavior","2026-03-17",{"date":197,"type":48},"2026-03-19",{"date":199,"type":48},"2025-01-15",{"date":201,"type":23},"2027-08-31",{"name":203,"class":55},"Child Trends",{"id":205,"slug":206,"hasResults":11,"nctId":207,"briefTitle":208,"officialTitle":209,"acronym":4,"eligibilityCriteria":210,"healthyVolunteers":11,"sex":18,"minAge":20,"maxAge":64,"enrollmentInfo":211,"targetDuration":4,"studyType":213,"phases":4,"briefSummary":214,"conditions":215,"keywords":222,"overallStatus":86,"whyStopped":4,"lastUpdateSubmitDate":233,"lastUpdatePostDateStruct":234,"startDateStruct":236,"completionDateStruct":238,"leadSponsor":240,"locationsCount":56},"100621860","effects-of-infertility-and-assisted-reproductive-technology-on-sexual-function-and-behavior-100621860","NCT07376109","Effects of Infertility and Assisted Reproductive Technology on Sexual Function and Behavior","Effect of Infertility and Assisted Reproductive Technology (ART) on Sexual Function and Behaviour","Inclusion Criteria:\n\n1. Assigned female at birth.\n2. Self-identify as a woman.\n3. Age 18-44 years.\n4. Diagnosis of infertility.\n5. Seeking fertility treatment at the MUHC Reproductive Centre.\n\nExclusion Criteria:\n\n1. Assigned male at birth.\n2. Age 45 years or older.\n3. Sexual practices that do not allow for the possibility of conception (e.g., same-sex relationships without use of assisted reproductive technologies).\n4. Seeking oocyte cryopreservation.\n5. Individuals who do not wish to complete the anonymous questionnaire.",{"count":212,"type":23},500,"OBSERVATIONAL","This cross-sectional observational study examines how infertility and the use of assisted reproductive technology (ART) are related to sexual function and sexual behaviors in women seeking fertility treatment. Infertility and the stress of ART may be associated with changes in sexual desire, satisfaction, and activity. The purpose is to better understand these associations to support the sexual health and overall well-being of women undergoing fertility care.\n\nWomen who are assigned female at birth, under 45 years old, diagnosed with infertility, and attending appointments at the MUHC Reproductive Centre are invited to take part. Participants will be asked to complete an anonymous questionnaire while waiting for their clinical visit. The questionnaire includes the validated Female Sexual Function Index (FSFI), which measures different aspects of sexual function, and additional questions about sexual activities, such as frequency of intercourse and other behaviors before and after fertility treatments.\n\nParticipants will not provide any identifying information. Completed questionnaires will be placed in a secure collection box to protect confidentiality.\n\nData from approximately 500 participants will be analyzed to explore how infertility type (primary vs. secondary), duration of infertility, and the number of unsuccessful ART cycles relate to sexual function and behavior. Findings from this study may help healthcare providers better recognize and address the sexual health concerns of women with infertility.\n\nThis study is approved by the McGill University Health Centre Research Ethics Board (REB #2025-11459).",[216,32,217,218,219,220,221],"Infertility Assisted Reproductive Technology","Sexual Function","Sexual Dysfunction and Infertility","Sexual Dysfunction Female","Infertility","Assisted Reproductive Techniques",[223,224,225,226,227,228,229,230,231,232],"infertility","Assisted Reproductive Technology","ART","IVF","female sexual function","female sexual function index","FSFI","sexual behavior","sexual dysfunction","women's sexual health","2026-02-19",{"date":235,"type":48},"2026-02-20",{"date":237,"type":48},"2026-02-06",{"date":239,"type":23},"2027-01",{"name":241,"class":55},"McGill University Health Centre\u002FResearch Institute of the McGill University Health Centre",{"id":243,"slug":244,"hasResults":11,"nctId":245,"briefTitle":246,"officialTitle":247,"acronym":4,"eligibilityCriteria":248,"healthyVolunteers":17,"sex":103,"minAge":20,"maxAge":249,"enrollmentInfo":250,"targetDuration":4,"studyType":24,"phases":252,"briefSummary":253,"conditions":254,"keywords":4,"overallStatus":86,"whyStopped":4,"lastUpdateSubmitDate":258,"lastUpdatePostDateStruct":259,"startDateStruct":261,"completionDateStruct":263,"leadSponsor":265,"locationsCount":56},"100613779","the-use-of-cannabidiol-suppositories-for-sexual-pain-100613779","NCT07271030","The Use of Cannabidiol Suppositories for Sexual Pain","The Use of Cannabidiol Suppositories for Sexual Pain: A Randomised Controlled Study","Inclusion Criteria:\n\n* Has previously used cannabidiol in any capacity and has not experienced any allergic reaction\n* Is experiencing sexual pain\n* There will be an absence of co occurring difficulties\n* Has attempted sexual intercourse in the last month\n* Age 18 years or older\n* Read and write English\n* Patient Health Questionnaire 9 screening score range between 0-9 mild\n* General Anxiety Disorder 7 screening score range between 0-9 mild\n* There are no restrictions on sex, gender, sexuality, or disability\n\nExclusion Criteria:\n\nHas experienced an allergic reaction to cannabidiol in any capacity\n\n* Has not attempted sexual intercourse in the last month\n* Has co occurring difficulties\n* Aged below 18 years old\n* Are not experiencing sexual pain\n* Patient Health Questionnaire 9 screening score range between moderate to severe - 10-27\n* General Anxiety Disorder 7 screening score range between 10- 21.","100 Years",{"count":251,"type":23},50,[26],"Research aim: To determine how cannabidiol suppositories might reduce sexual pain during intimacy. Outcomes are also hoped to increase sexual functioning, well-being, and quality of life.\n\nResearch intention: If cannabidiol suppository intervention reduces sexual pain and increases general well-being, then this research would be repeated on a larger scale, targeting psychosexual services.\n\nA brief overview of the intervention:\n\nQuantitatively, randomisation of cannabidiol suppositories will be into dose-specific groups. The intervention will be delivered over a period of one month, with follow-up scheduled at 12 weeks. Qualitatively, participants were asked approximately eight open-ended feedback questions throughout the study.",[255,256,32,257],"Well-Being, Psychological","Quality of Life","Sexual Pain Disorder","2026-01-23",{"date":260,"type":48},"2026-01-26",{"date":262,"type":48},"2026-01-16",{"date":264,"type":23},"2026-08",{"name":266,"class":55},"London Metropolitan University",{"id":268,"slug":269,"hasResults":11,"nctId":270,"briefTitle":271,"officialTitle":272,"acronym":273,"eligibilityCriteria":274,"healthyVolunteers":17,"sex":103,"minAge":275,"maxAge":19,"enrollmentInfo":276,"targetDuration":4,"studyType":24,"phases":278,"briefSummary":279,"conditions":280,"keywords":284,"overallStatus":44,"whyStopped":4,"lastUpdateSubmitDate":291,"lastUpdatePostDateStruct":292,"startDateStruct":294,"completionDateStruct":296,"leadSponsor":298,"locationsCount":56},"100608937","cultural-adaptation-validation-and-evaluation-of-the-programme-for-promotion-of-healthy-affective-sexual-behaviours-in-adolescents-iyg-100608937","NCT07208045","Cultural Adaptation, Validation, and Evaluation of the Programme for Promotion of Healthy Affective-Sexual Behaviours in Adolescents (IYG)","Es tu Juego: Decide Bien [It's Your Game: Keep It Real]. Cultural Adaptation, Validation, and Evaluation of the Programme for Promotion of Healthy Affective-Sexual Behaviours in Adolescents","IYG","Inclusion Criteria:\n\n* Adolescents aged between 11 and 14 years enrolled in compulsory secondary education (E.S.O).\n* Access to a computer and internet at their educational centre.\n\nExclusion Criteria:\n\n* Presence of linguistic, cognitive, or sensory barriers that prevent completion of the questionnaire\n* Participation in another programme aimed at preventing affective-sexual risk behaviours.","11 Years",{"count":277,"type":23},1200,[26],"The investigators are writing to inform participants about a study being carried out by a research group from the University of Granada and the University of Seville, in which the participant's son\u002Fdaughter is invited to participate. The study has been approved by the Provincial Research Ethics Committee of Granada under code 202499906944441.\n\nThe sole intention of the investigators is to ensure that participants receive correct and sufficient information to assess and decide whether or not to give consent for the child's participation in this study. The information sheet should be read carefully, and any questions may be addressed to the investigators.\n\nThe objective of the study is to culturally adapt the program It's Your Game: Keep it Real (IYG), which aims to prevent risky sexual and affective behaviors in adolescents. The IYG program consists of 12 lessons, each lasting 45 minutes. These lessons aim to help the child identify personal norms and boundaries regarding sexuality, recognize situations that might challenge these boundaries, and develop refusal skills to maintain them. The program also covers topics such as the characteristics of healthy and unhealthy relationships, friendships, anatomy and reproduction, the social, emotional, and physical consequences of sexual activity, the consequences of teenage pregnancy and STIs, condom and contraceptive use, and communication skills.\n\nThis adaptation will involve the child completing all 12 lessons (two lessons per week over a period of six weeks) that make up the IYG program, as well as filling out a series of questionnaires. These questionnaires will allow the investigators to assess the usability of the program in Spain (including ease of use, comprehension, acceptability, as well as aspects most liked and suggestions for improvement).\n\nParticipation is entirely VOLUNTARY AND ANONYMOUS, and consent may be withdrawn at any time, without providing any explanation and without this affecting the care the child will receive in any way.\n\nIn all cases, the CONFIDENTIALITY of the data collected will be maintained in accordance with the European Union General Data Protection Regulation (GDPR) 2016\u002F679 and the Spanish Organic Law on the Protection of Personal Data and Guarantee of Digital Rights (LOPD-GDD) 3\u002F2018, of December 5.\n\nRegarding the study results, these may be shared with the scientific community through presentations, conferences, and\u002For publications.\n\nThe investigators express appreciation in advance for cooperation in this study.",[32,30,281,282,283],"Condom Use","Adolescent Health","Cultural Adaptation",[285,286,169,287,288,289,290],"sexually behaviour","sex education","health education","cultural adaptation","evidence-based prevention","school health","2025-09-28",{"date":293,"type":48},"2025-10-08",{"date":295,"type":23},"2025-10-01",{"date":297,"type":23},"2027-06-30",{"name":299,"class":55},"University of Seville",{"id":301,"slug":302,"hasResults":11,"nctId":303,"briefTitle":304,"officialTitle":305,"acronym":4,"eligibilityCriteria":306,"healthyVolunteers":11,"sex":307,"minAge":308,"maxAge":309,"enrollmentInfo":310,"targetDuration":4,"studyType":24,"phases":312,"briefSummary":313,"conditions":314,"keywords":318,"overallStatus":86,"whyStopped":4,"lastUpdateSubmitDate":321,"lastUpdatePostDateStruct":322,"startDateStruct":324,"completionDateStruct":326,"leadSponsor":328,"locationsCount":56},"100528293","alcohol--mens-sexual-risk-behaviors-100528293","NCT06158880","Alcohol & Men's Sexual Risk Behaviors","Men's Sexual Risk Behaviors: Alcohol, Sexual Aggression, and Emotional Factors (Extension)","Inclusion Criteria:\n\n* Single\n* Male\n* Ages 21-30\n* Engagement in unprotected intercourse with a woman at least once in the past year\n* Consumed alcohol at least 1 time per week in the past 30 days\n* Had sex with a woman at least 2 times in the past 30 days\n\nExclusion Criteria:\n\n* A history of alcohol problems\n* A medical condition and\u002For medications which contraindicate alcohol consumption\n* In a relationship that is monogamous and has lasted longer than 6 months","MALE","21 Years","30 Years",{"count":311,"type":23},320,[26],"This project extends the investigators' previous research regarding the intersecting risks of alcohol, sexual risk behavior (SRB), and sexual aggression (SA) in male drinkers who have sex with women by examining the mediating and moderating roles of both intrapersonal and interpersonal emotional factors. While independent streams of research consistently document alcohol's role in SRB and SA, the investigators' work has demonstrated that these behaviors are related, and that alcohol exacerbates their likelihood both independently and synergistically. The researchers' investigations focus on a particular type of SRB: men's resistance to condom use with female partners who want to have protected sex. Condom use resistance (CUR) is common and normative among young male drinkers, with up to 80% of men reporting engaging in CUR. Of particular concern, research demonstrates that up to 42% of men report using coercive CUR tactics such as emotional manipulation, deception, condom sabotage, and force to obtain unprotected sex. Investigators will evaluate hypotheses that distal and proximal emotional and alcohol factors influence in-the-moment SRB\u002FCUR intentions as well as daily alcohol use and SRB\u002FCUR. The investigators will also examine whether the relationships among assessed variables are similar across experimental and naturalistic settings. That is, investigate the extent to which men's responses in the lab parallel their real-world drinking and SRB\u002FCUR behaviors, particularly regarding self and partner emotions, empathy, and interpersonal stress.",[32,315,316,317],"Alcohol Drinking","Sexual Aggression","Emotions",[319,320],"Condom use resistance","Emotion dysregulation","2025-07-02",{"date":323,"type":48},"2025-07-04",{"date":325,"type":48},"2024-06-17",{"date":327,"type":23},"2027-12",{"name":329,"class":55},"Arizona State University",{"id":331,"slug":332,"hasResults":11,"nctId":333,"briefTitle":334,"officialTitle":335,"acronym":336,"eligibilityCriteria":337,"healthyVolunteers":11,"sex":103,"minAge":20,"maxAge":338,"enrollmentInfo":339,"targetDuration":4,"studyType":24,"phases":341,"briefSummary":342,"conditions":343,"keywords":352,"overallStatus":86,"whyStopped":4,"lastUpdateSubmitDate":363,"lastUpdatePostDateStruct":364,"startDateStruct":366,"completionDateStruct":368,"leadSponsor":370,"locationsCount":120},"100581602","troubled-desire--therapeutic-chat-for-reduction-of-csam-use-td-chat-100581602","NCT06852443","Troubled-Desire & Therapeutic Chat for Reduction of CSAM Use (TD-CHAT)","Troubled Desire & Therapeutic Chat for Reduction of CSAM Use","TD-CHAT","Inclusion Criteria:\n\n* Adult participant (≥18 years);\n* recent (last 2 weeks) CSAM use or past CSAM use and self-reported risk;\n* proficiency in English, German or Spanish;\n* voluntary participation and agreement to the terms of the study.\n\nExclusion Criteria:\n\n* Severe neuropsychiatric comorbidities (unstable psychotic disorder, organic brain damage, diminished intellectual functioning, untreated drug or alcohol addiction);\n* history of contact CSA perpetration (past or present);\n* ongoing criminal investigation, trial, punishment, or probation status for online or offline CSA or CSAM use;\n* current inpatient psychiatric treatment or other concurrent treatment targeting CSAM behaviours","99 Years",{"count":340,"type":23},180,[26],"The goal of this prospective multicentred, stratified, parallel-group superiority study is to prevent and reduce the usage of Child Sexual Abuse Material (CSAM) by a Therapist Chat Service (TCS) and Selfhelp Platform for Self-Referred Patients, mostly men with a sexual interest in children. The interventions are based on Cognitive Behavioral Therapy (CBT) principles and designed to treat the sexual behavioral disorder related with CSAM consumption.\n\n1. Participants in the Selfhelp modules group will show a statistically significantly higher proportion of reduction in CSAM behaviours four weeks after baseline, as compared to participants in the waitlist control group.\n2. Participants in the Selfhelp modules followed by TCS group will show a statistically significantly higher reduction of CSAM behaviours compared to participants in the Selfhelp-only and TCS-only groups, post-intervention.\n\nResearchers will compare TCS-only-, Selfhelp-only-, Selfhelp + TCS- and Waiting group to see if if the interventions decrease CSAM use and improve mental well-being.\n\nParticipants will get web based selfhelp-modules and\u002For text-based chat intervention operated by trained therapists.",[344,345,32,346,347,348,349,350,351],"Prevention","Well Being","Behavior Change","Behavior Problems","Behavior Change Interventions","Child Sexual Abuse Material (CSAM) Consumption","Behavioral Disorder","Online Behaviour",[353,354,355,356,357,358,359,360,361,362],"Child Sexual Abuse Material (CSAM) consumption","CSAM","Child Sexual Abuse","Digital online intervention","CSA","CBT","iCBT","Cognitive Behavioural Therapy","Pedophilia","chat Intervention","2025-05-06",{"date":365,"type":48},"2025-05-07",{"date":367,"type":48},"2025-04-01",{"date":369,"type":23},"2026-07-31",{"name":371,"class":55},"Charite University, Berlin, Germany",{"id":373,"slug":374,"hasResults":11,"nctId":375,"briefTitle":376,"officialTitle":377,"acronym":4,"eligibilityCriteria":378,"healthyVolunteers":17,"sex":103,"minAge":379,"maxAge":187,"enrollmentInfo":380,"targetDuration":4,"studyType":24,"phases":382,"briefSummary":383,"conditions":384,"keywords":387,"overallStatus":86,"whyStopped":4,"lastUpdateSubmitDate":393,"lastUpdatePostDateStruct":394,"startDateStruct":396,"completionDateStruct":398,"leadSponsor":400,"locationsCount":56},"100560640","evaluation-of-parent-toolkit-20-morehouse-family-health-study-100560640","NCT06579781","Evaluation of Parent Toolkit 2.0 (Morehouse Family Health Study)","Rigorous Evaluation of Morehouse School of Medicine's Parent Toolkit 2.0 Intervention (Morehouse Family Health Study)","Inclusion Criteria for Adult Participants:\n\n* 25 to 70 years old\n* Lives in an eligible zip code in Georgia\n* Parent or caregiver of 12- to 15-year-old child who wants to participate in this study with them\n* Lives with child at least 50% of the time\n\nExclusion Criteria for Adult Participants:\n\n* Lives in a home with a child who is already enrolled in this study\n* Raises child with an adult who is already enrolled in this study\n\nInclusion Criteria for Child Participants:\n\n* 12-15 years old\n* Lives with a parent or caregiver who wants to participate in this study with them\n* Able to complete surveys on own or with help of support person\n\nExclusion Criteria for Child Participants:\n\n\\- Does not have their own email address or phone number","12 Years",{"count":381,"type":23},2000,[26],"Child Trends will conduct a randomized control trial evaluation of Parent Toolkit 2.0, an innovative intervention for parents and caregivers of middle and high school students. Child Trends will collaborate with Morehouse School of Medicine and Tressa Tucker \\& Associates, LLC to implement and evaluate the program with 1,000 parent-teen pairs across Georgia. The program includes three components that will be delivered across a three-week period: (1) an online self-paced Parent Guide with information, tips, tools, and resources on adolescent health, including sexual health; (2) four videos modeling parent-teen communication around sex and contraception; and (3) two group-based sessions for parent participants to discuss program content and improve communication skills. The program aims to increase parent knowledge and parent-teen communication about adolescent health, sexual health, and relationships to help youth adopt health-promoting behaviors such as delaying sexual initiation and increasing contraceptive use.",[32,194,385,74,386],"Sexually Transmitted Diseases","Parent-Child Relations",[388,389,390,391,392],"teen pregnancy","STIs","parent-teen communication","parenting","adolescent sexual health","2025-04-25",{"date":395,"type":48},"2025-04-30",{"date":397,"type":48},"2024-10-21",{"date":399,"type":23},"2028-09-29",{"name":203,"class":55},{"id":402,"slug":403,"hasResults":11,"nctId":404,"briefTitle":405,"officialTitle":406,"acronym":4,"eligibilityCriteria":407,"healthyVolunteers":17,"sex":18,"minAge":20,"maxAge":188,"enrollmentInfo":408,"targetDuration":4,"studyType":24,"phases":410,"briefSummary":411,"conditions":412,"keywords":4,"overallStatus":86,"whyStopped":4,"lastUpdateSubmitDate":414,"lastUpdatePostDateStruct":415,"startDateStruct":417,"completionDateStruct":419,"leadSponsor":421,"locationsCount":56},"100486959","young-adult-education-on-alcohol--health-100486959","NCT05620849","Young Adult Education on Alcohol & Health","A Technology-based Intervention for Alcohol-related Sexual Risk Behaviors in Young Women","Inclusion Criteria:\n\n* Assessed as part of screening procedures\n\nExclusion Criteria:\n\n* Do not want to participate",{"count":409,"type":23},300,[26],"The goal of this clinical trial is to test the effectiveness of our brief online program when compared to those who don't complete the program at all.",[32,315,413],"Condomless Sex","2024-12-05",{"date":416,"type":48},"2024-12-09",{"date":418,"type":48},"2023-09-15",{"date":420,"type":23},"2026-01-31",{"name":422,"class":55},"University of Washington",{"id":424,"slug":425,"hasResults":11,"nctId":426,"briefTitle":427,"officialTitle":427,"acronym":428,"eligibilityCriteria":429,"healthyVolunteers":17,"sex":103,"minAge":20,"maxAge":4,"enrollmentInfo":430,"targetDuration":4,"studyType":213,"phases":4,"briefSummary":432,"conditions":433,"keywords":442,"overallStatus":86,"whyStopped":4,"lastUpdateSubmitDate":444,"lastUpdatePostDateStruct":445,"startDateStruct":447,"completionDateStruct":449,"leadSponsor":450,"locationsCount":56},"100550145","cerebrovascular-disease-quality-of-life-code-qol-100550145","NCT06443268","Cerebrovascular Disease: Quality of Life (CODE: QoL)","CODE:QoL","Control group:\n\nInclusion criteria:\n\n* over 18 years old\n* No previous stroke OR previous stroke \\>3 years ago\n* No significant disability (maximum mRS 1)\n* ambulatory patients at the University Hospital of Zurich (USZ), Dept. of Neurology\n* Patients' AND caregiver's ability to give informed consent\n* Patients' AND close relative's \u002F caregiver's willingness to participate\n\nExclusion criteria:\n\n• Medication with steroid hormones (prednisone, prednisolone, dexamethasone, methylprednisolone, hydrocortisone etc.) within last 3 months\n\nMain Group:\n\nInclusion criteria:\n\n* over 18 years old\n* Patients diagnosed with either transient ischemic attack, ischemic stroke or intracerebral hemorrhage and their caregivers\n* Caregiver of a patient as described above, age over 18 years\n* Hospitalized or ambulatory patients at the University Hospital of Zurich (USZ) included within 28 days from event.\n* Patients' AND caregiver's ability to give informed consent\n* Patients' AND caregiver's willingness to participate\n\nExclusion criteria:\n\n• Medication with steroid hormones (prednisone, prednisolone, dexamethasone, methylprednisolone, hydrocortisone etc.) within last 3 months",{"count":431,"type":23},680,"The goal of this observational study is to learn about quality of life, stress and caregiver burden in patients with stroke and their caregivers.\n\nThe main question is:\n\n• to discover the factors associated with quality of life and stress in patient-caregiver dyads.\n\nParticipants will be asked to fill out questionnaires and agree to provide a hair sample (in order to measure stress hormones in hair) and consent to use of their routine clinical and laboratory data.\n\nResearchers will compare a group of participants without stroke to establish a comparable baseline.",[256,434,32,435,436,437,438,439,440,441],"Stroke, Acute","Stress","Cortisol Excess","Incontinence, Urinary","Caregiver Burden","Transient Ischemic Attack","Intracerebral Hemorrhage","Cerebrovascular Disorders",[443],"Stroke, QoL, HRQoL, Patient-Caregiver dyads, Stress, Burden","2024-05-29",{"date":446,"type":48},"2024-06-05",{"date":448,"type":48},"2023-05-27",{"date":52,"type":23},{"name":451,"class":55},"University of Zurich",{"id":453,"slug":454,"hasResults":11,"nctId":455,"briefTitle":456,"officialTitle":456,"acronym":457,"eligibilityCriteria":458,"healthyVolunteers":17,"sex":103,"minAge":129,"maxAge":459,"enrollmentInfo":460,"targetDuration":4,"studyType":213,"phases":4,"briefSummary":462,"conditions":463,"keywords":4,"overallStatus":86,"whyStopped":4,"lastUpdateSubmitDate":464,"lastUpdatePostDateStruct":465,"startDateStruct":467,"completionDateStruct":469,"leadSponsor":471,"locationsCount":56},"100504458","keeping-it-lite-exploring-hiv-risk-in-vulnerable-youth-with-limited-interaction-and-digital-health-intervention-100504458","NCT05848570","Keeping it LITE: Exploring HIV Risk in Vulnerable Youth With Limited Interaction and Digital Health Intervention","LITE-2","Inclusion Criteria:\n\n* For young adults ages 18-34: self-identified SGM young adults ages 18-34 who meet at least one of the following criteria:\n\n  * 1\\) condomless anal or vaginal intercourse (CAI) with a cisgender man in the last 6 months OR\n  * 2\\) sex with cisgender men and bacterial STI in the last 6 months OR\n  * 3\\) anal or vaginal sex with a known HIV-infected partner in the last 6 months.\n* For adolescents 13-17: self-identified SGM adolescents ages 13-17 who have engaged in any sexual activity (e.g., oral, anal or vaginal sex)\n\nExclusion Criteria:\n\n* under age 13\n* over age 34","34 Years",{"count":461,"type":23},6000,"Despite advances in HIV diagnostics, care and prevention strategies, infection rates among adolescent and young adult sexual and gender minorities (SGM) continue to rise in the United States (US). There is an urgent need to describe the epidemiology and trajectories of HIV acquisition in this population and to offer age and culturally appropriate scalable prevention interventions to those at highest risk of infection in the US. This project will engage and retain young SGM in an innovative longitudinal cohort, enroll participants in a dynamic established digital health retention platform (HMP; HealthMPowerment), monitor HIV risk and prevention behaviors and explore the socioecological factors that influence the use of new HIV prevention technologies (UG3 phase), while also allowing targeted testing of novel digital health interventions (UH3 phase). In Aim 1, the investigators will enroll and retain a large (n=6000; 3000\u002Fyear), diverse cohort of sexually active, SGM adolescents and young adults, ages 13-34, using innovative digital recruitment, engagement and retention strategies. Over the course of the study, the investigators will longitudinally characterize the sexual behavior, HIV transmission risk, and PrEP uptake trajectories of SGM youth utilizing epidemiological trajectory analyses to identify the most effective points of intervention (Aim 2). This study will capitalize upon productive existing partnerships and digital health expertise to articulate the drivers of the ongoing HIV epidemic among the most vulnerable populations in the US in order to identify the most effective, expeditious and scalable strategies to address this ongoing public health crisis.",[136,32],"2023-04-27",{"date":466,"type":48},"2023-05-08",{"date":468,"type":48},"2023-03-23",{"date":470,"type":23},"2027-05",{"name":472,"class":55},"Hektoen Institute for Medical Research"]