[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"shame\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:shame":26},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,5,0,[8,48,73,98,135],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":14,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":4,"briefSummary":22,"conditions":23,"keywords":29,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":36,"lastUpdatePostDateStruct":37,"startDateStruct":40,"completionDateStruct":42,"leadSponsor":44,"locationsCount":47},"100640395","resilience-and-recovery-after-intimate-partner-violence---evaluation-of-the-ember-ipv-protocol-100640395",false,"NCT07606586","Resilience and Recovery After Intimate Partner Violence - Evaluation of the EMBER-IPV Protocol","EMBER-3","Inclusion Criteria:\n\n* Women taking part of the EMBER intervention (phase A or C)\n* Subjected to IPV within the past 2 years prior to enrollment\n\nExclusion Criteria:\n\n* Ongoing severe intimate partner violence\n* Ongoing severe substance abuse\n* Severe mental health problems such as psychosis, suicidality","FEMALE","18 Years",{"count":19,"type":20},150,"ESTIMATED","OBSERVATIONAL","The EMBER-protocol is an intervention used at the NCK clinic at Uppsala University Hospital with the purpose of helping women utilize their resilience and strengths in order to recover after intimate partner violence. This study is conducted in order to explore how health and resilience changes during the course of the EMBER-intervention. The participants are asked to complete questionnaires before, during and after the intervention.",[24,25,26,27,28],"Intimate Partner Violence","Intimate Partner Violence Against Women","Shame","Domestic Abuse","Resilience, Psychological",[24,30,31,32,26,33,34],"Domestic Violence","domestic violence exposure","gender-based violence","Resilience, psychological","resilience intervention","NOT_YET_RECRUITING","2026-05-18",{"date":38,"type":39},"2026-05-26","ACTUAL",{"date":41,"type":20},"2026-05",{"date":43,"type":20},"2029-04",{"name":45,"class":46},"Uppsala University","OTHER",1,{"id":49,"slug":50,"hasResults":11,"nctId":51,"briefTitle":52,"officialTitle":53,"acronym":54,"eligibilityCriteria":55,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":56,"targetDuration":4,"studyType":21,"phases":4,"briefSummary":58,"conditions":59,"keywords":61,"overallStatus":64,"whyStopped":4,"lastUpdateSubmitDate":65,"lastUpdatePostDateStruct":66,"startDateStruct":68,"completionDateStruct":70,"leadSponsor":72,"locationsCount":47},"100611064","how-a-resilience-focused-intervention-is-perceived-by-women-subjected-to-domestic-violence-100611064","NCT07235722","How a Resilience-Focused Intervention is Perceived by Women Subjected to Domestic Violence","Exploring Resilience. A Qualitative Study of an Intervention After Intimate Partner Violence.","EMBER-2","Inclusion Criteria:\n\n* Enrolled in the EMBER intervention at the NCK outpatient clinic.\n\nExclusion Criteria:\n\n* Any situation that, in the opinion of the Investigator, would compromise the safety of the patient or the quality of the data.",{"count":57,"type":20},30,"At Uppsala University Hospital, there is an outpatient clinic for women subjected to intimate partner violence. In order to explore how patients experience the biopsychosocial resilience-based intervention in use at the clinic and how well the intervention fits the needs of the patients, 30 patients from different stages of their contact at the clinic and with diverse life situations and background are enrolled. The researchers will carry out individual in-person interviews, each lasting approximately 60 minutes, based on a semi-structured set of questions. The questions concern the participant´s life situation, resilience and self-perceived needs, how well the intervention has met those needs and how it was perceived by the participant. The interviews are audio-recorded and transcribed verbatim for thematic analysis.",[26,24,60,28],"Domestic Violence Exposure",[62,63,24,30,31,32,26,28],"Qualitative","interview","RECRUITING","2026-04-08",{"date":67,"type":39},"2026-04-13",{"date":69,"type":39},"2026-04-07",{"date":71,"type":20},"2027-03",{"name":45,"class":46},{"id":74,"slug":75,"hasResults":11,"nctId":76,"briefTitle":77,"officialTitle":78,"acronym":79,"eligibilityCriteria":80,"healthyVolunteers":81,"sex":82,"minAge":17,"maxAge":4,"enrollmentInfo":83,"targetDuration":4,"studyType":21,"phases":4,"briefSummary":85,"conditions":86,"keywords":87,"overallStatus":64,"whyStopped":4,"lastUpdateSubmitDate":65,"lastUpdatePostDateStruct":92,"startDateStruct":93,"completionDateStruct":95,"leadSponsor":97,"locationsCount":47},"100608854","validation-of-the-swedish-translation-of-a-brief-shame-measure-the-external-and-internal-shame-scale-100608854","NCT07206966","Validation of the Swedish Translation of a Brief Shame Measure, the External and Internal Shame Scale","Validation of the Swedish Translation of a Brief Shame Measure, the External and Internal Shame Scale (EISS)","EMBER-1","Inclusion Criteria\n\n* Must be 18 years of age or above\n* Must be capable of communicating in Swedish\n* Participants in clinical samples must be patients at one of the clinics involved in the study.\n\nExclusion criteria\n\n* None.",true,"ALL",{"count":84,"type":20},350,"Shame is a normal emotion that people sometimes have. Experiencing a lot of shame has however been found to have a link to ill mental and somatic health. Therefore it is of interest to have a brief way of measuring shame. External and Internal shame scale (EISS) is a questionnaire with 8 items that is available in several languages, but not yet in Swedish. The researchers have translated it to Swedish and will investigate how well the Swedish version works for measuring shame. 300 participants are enrolled via social media and asked to complete the EISS as well as two other scales for comparison. Participants are also asked about their age and gender. In addition 50 participants will be recruited from an outpatient clinic in order to check how the scale works in clinical settings. The researchers will use the answers to statistically calculate the scientific properties of the EISS.",[26],[88,89,26,90,91],"Psychometrics","Psychological Tests","Patient Health Questionnaire","Surveys and Questionnaires",{"date":67,"type":39},{"date":94,"type":39},"2025-10-23",{"date":96,"type":20},"2026-08",{"name":45,"class":46},{"id":99,"slug":100,"hasResults":11,"nctId":101,"briefTitle":102,"officialTitle":103,"acronym":104,"eligibilityCriteria":105,"healthyVolunteers":11,"sex":82,"minAge":106,"maxAge":17,"enrollmentInfo":107,"targetDuration":4,"studyType":109,"phases":110,"briefSummary":112,"conditions":113,"keywords":117,"overallStatus":64,"whyStopped":4,"lastUpdateSubmitDate":126,"lastUpdatePostDateStruct":127,"startDateStruct":129,"completionDateStruct":131,"leadSponsor":133,"locationsCount":47},"100615545","shame-focused-cognitive-behavioral-therapy-for-reducing-suicide-risk-in-adolescent-psychiatric-inpatients-sf-cbt-100615545","NCT07294001","Shame-Focused Cognitive Behavioral Therapy For Reducing Suicide Risk In Adolescent Psychiatric Inpatients (SF-CBT)","A Pilot Randomized Controlled Trial Of Shame-Focused Cognitive Behavioral Therapy For Suicide Prevention In Adolescent Psychiatric Inpatients","SF-CBT","Inclusion Criteria:\n\n* Adolescents aged 13-18 years, male or female.\n* Recent suicide risk, defined as:\n\nAt least one suicide attempt in the past month, or Current suicidal ideation within the past month (with or without plan\u002Fintent) and at least one previous attempt.\n\n* Elevated shame level (baseline score ≥ 9 on the External and Internal Shame Scale, EISS).\n* Adequate cognitive capacity to participate in interviews and assessments.\n* Parent\u002Flegal guardian (or designated responsible adult authorized by guardian) provides informed consent and agrees to participate.\n\nExclusion Criteria:\n\n* Current manic episode.\n* History of schizophrenia spectrum disorder, intellectual disability, or organic brain disease.\n* Severe psychiatric or medical conditions that impair capacity for consent or participation.\n* Expected to receive electroconvulsive therapy (ECT) during hospitalization.\n* Anticipated inpatient stay shorter than 14 days (to ensure intervention completion).","13 Years",{"count":108,"type":20},42,"INTERVENTIONAL",[111],"NA","This pilot randomized controlled trial (RCT) aims to evaluate the feasibility, acceptability, and preliminary efficacy of Shame-Focused Cognitive Behavioral Therapy (SF-CBT) among high-risk psychiatric inpatient adolescents. Shame has been identified as a critical psychological mechanism underlying suicidal ideation and behavior, yet few interventions directly target it. SF-CBT is a structured, manualized intervention designed to reduce shame, improve coping strategies, and lower suicide risk.\n\nApproximately 42 adolescents aged 13-18 years, admitted for recent suicide attempt or severe suicidal ideation, will be randomized in a 2:1 ratio to receive either SF-CBT or supportive therapy (ST). Both conditions include 7 individual sessions for adolescents and 3 structured psychoeducation sessions for parents\u002Fguardians.\n\nPrimary outcomes include feasibility metrics (recruitment, retention, adherence, fidelity, adverse events) and acceptability ratings from adolescents, parents, and therapists. Secondary outcomes include changes in suicidal ideation, suicidal behavior, shame, and coping styles, assessed at baseline, post-treatment, and 1-, 3-, and 6-month follow-ups.\n\nFindings will inform refinement of the intervention manual, establish feasibility benchmarks, and provide effect size estimates to guide a subsequent large-scale RCT.",[114,115,116,26],"Adolescent Suicide","Suicidal Ideation","Suicidal Behavior",[118,119,115,116,26,120,121,122,123,124,125],"Adolescents","Suicide Prevention","Cognitive Behavioral Therapy (CBT)","Shame-Focused Cognitive Behavioral Therapy (SF-CBT)","Randomized Controlled Trial (RCT)","Feasibility Study","Pilot Trial","Psychiatric Inpatient","2025-12-07",{"date":128,"type":39},"2025-12-19",{"date":130,"type":39},"2025-08-10",{"date":132,"type":20},"2026-09-30",{"name":134,"class":46},"Peking University",{"id":136,"slug":137,"hasResults":11,"nctId":138,"briefTitle":139,"officialTitle":139,"acronym":140,"eligibilityCriteria":141,"healthyVolunteers":11,"sex":82,"minAge":17,"maxAge":4,"enrollmentInfo":142,"targetDuration":4,"studyType":109,"phases":144,"briefSummary":145,"conditions":146,"keywords":150,"overallStatus":64,"whyStopped":4,"lastUpdateSubmitDate":158,"lastUpdatePostDateStruct":159,"startDateStruct":161,"completionDateStruct":163,"leadSponsor":165,"locationsCount":47},"100407458","healthy-recovery-after-trauma-study-100407458","NCT04585685","Healthy Recovery After Trauma Study","HRT","Inclusion Criteria:\n\n* individuals with a history of sexual trauma meeting past-month diagnostic criteria for PTSD (meeting diagnostic status on the DIAMOND and score greater than or equal to 36 on the PCL-5) and\n* reporting current experiences of trauma-related mental contamination (greater than or equal to 10 on the PEMC).\n* 18 years of age or older\n* fluent in English\n* Patients on psychotropic medications will be included if they have been maintained on a stable dose for at least 4 weeks prior to beginning the study and are willing to maintain a stable dosage throughout the study period; this procedure allows for a broader range of participants and avoids having outcomes assessment confounded by the initiation of medication during treatment.\n* Finally, patients must be willing to refrain from additional trauma-related treatment for the duration of the study.\n\nExclusion Criteria:\n\n* We will exclude individuals diagnosed with psychological conditions that may be better addressed by alternative treatments; these conditions include\n* psychotic disorders\n* dissociative identity disorder\n* unmanaged (i.e., unmedicated or currently experiencing a manic\u002Fhypomanic episode) bipolar disorder\n* bulimia nervosa\n* anorexia nervosa\n* imminent risk of suicide (i.e., intent\u002Fplan)\n* severe substance use disorders.",{"count":143,"type":20},12,[111],"Mental contamination-an internal experience of dirtiness evoked in the absence of physical contact with an external source-has been linked to the development and maintenance of posttraumatic stress disorder (PTSD) following exposure to sexual abuse or assault (Adams et al., 2014; Badour et al., 2013; Brake et al., 2017). Mental contamination has been associated with greater PTSD severity (Rachman et al., 2015) and higher elevations in specific PTSD symptom clusters (particularly those of intrusive reexperiencing, negative cognitions\u002Fmood, and arousal\u002Freactivity; Brake et al., 2019; Fergus \\& Bardeen, 2016). Additionally, trauma-related mental contamination has been linked to a number of negative posttraumatic emotions such as shame, guilt, disgust, and anger (Fairbrother \\& Rachman, 2004; Radomsky \\& Elliott, 2009) Despite clear and consistent links between mental contamination and problematic posttraumatic outcomes following sexual trauma, there is a dearth of research investigating how existing or promising new interventions for PTSD impact mental contamination.\n\nCognitive Processing Therapy (CPT) is an efficacious and effective 12-session manualized cognitive-behavioral intervention for PTSD that is considered a gold-standard empirically-supported treatment for PTSD that is recommended by the American Psychological Association (APA, 2017). In addition to PTSD symptom improvement, CPT has also demonstrated benefit for improving feelings of shame and guilt, which are often seen among individuals with trauma-related mental contamination (Nishith et al., 2005; Resick et al., 2002, 2008). Cognitive reappraisal, a primary technique employed in CPT, involves challenging one's view of an emotionally-eliciting situation to alter its emotional impact (Gross \\& John, 2003). However, some investigators have suggested that cognitive reappraisal may be less effective in targeting moral emotions such as shame, guilt, and self-disgust that are based on an individual's standards and virtues (Finlay, 2015). Self-compassion (SC; i.e., self-directed care and kindness; forgiveness; and feelings of common humanity; Neff, 2003) has been proposed as an alternative method for addressing trauma-related shame and preliminary evidence suggests a 6-session self-compassion intervention may have benefit for reducing both PTSD symptoms and trauma-related shame (Au et al., 2017). Given the centrality of shame, guilt, and self-disgust to the experience of mental contamination, and the fact that mental contamination often arises in response to experiences involving moral violation or betrayal (Millar et al., 2016; Rachman, 2010), a SC intervention for PTSD may also offer promise as a standalone or adjunctive intervention for reducing trauma-related mental contamination. A test of these interventions for their impact on reducing trauma-related mental contamination is needed.\n\nThe current study will use Single Case Experimental Design to isolate and evaluate the effects of CPT and SC in reducing both PTSD symptoms and trauma-related mental contamination among individuals with PTSD resulting from sexual trauma.\n\nAims: 1) explore whether participants demonstrate reductions in mental contamination and PTSD symptoms in response to 12-sessions of CPT or 6-sessions of a SC intervention; 2) evaluate whether presentation of either treatment first yields differences in symptom reduction for PTSD and\u002For mental contamination symptoms; 3) evaluate whether the addition of the alternative module will enhance reductions in PTSD symptoms and mental contamination; 4) evaluate if such reductions are maintained during follow-up.\n\nVisual inspection analysis and statistical methods will be used to draw conclusions regarding the effects of the interventions on PTSD symptoms and mental contamination.",[147,26,148,149],"Stress Disorders, Post-Traumatic","Guilt","Sexual Assault and Rape",[151,152,153,154,155,156,157],"post-traumatic stress disorder","mental contamination","cognitive processing therapy","self-compassion","shame","guilt","sexual trauma","2025-11-05",{"date":160,"type":39},"2025-11-10",{"date":162,"type":39},"2020-09-10",{"date":164,"type":20},"2026-11",{"name":166,"class":46},"Christal L Badour"]