[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"shock-state\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:shock-state":25},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,45],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":23,"conditions":24,"keywords":29,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":34,"lastUpdatePostDateStruct":35,"startDateStruct":38,"completionDateStruct":40,"leadSponsor":42,"locationsCount":5},"100635619","correlation-between-capillary-refill-time-and-perfusion-index-in-critically-ill-patients-100635619",false,"NCT07555041","Correlation Between Capillary Refill Time and Perfusion Index in Critically Ill Patients","Correlation Between Capillary Refilling tIme and Perfusion Index in Critically Ill Patients","CRIPI","Inclusion criteria :\n\n* Adult patient.\n* Admission within the previous 24 hours, or within 24 hours of the onset of a hemodynamic instability criterion (requirement for vasopressors or fluid resuscitation).\n* Absence of patient objection.\n\nExclusion criteria :\n\n* Legal guardianship, curatorship, or judicial protection.\n* No social security coverage.\n* Morphological abnormalities preventing CRT and IP measurements.","ALL","18 Years",{"count":20,"type":21},250,"ESTIMATED","OBSERVATIONAL","Assessment of capillary refill time (CRT) is a cornerstone of tissue perfusion monitoring in critically ill patients.\n\nCRT measurement is performed by applying brief and gentle pressure (for a few seconds) to a small area of skin until blanching occurs. CRT is defined as the time, in seconds, required for the skin surface to return to its initial color after release of pressure.\n\nAlthough CRT is a monitoring tool used on a daily basis in emergency departments and critical care units, its practical measurement modalities remain poorly standardized and time-consuming. Consequently, there is no consensus regarding the most reproducible bedside method for CRT assessment. Moreover, repeated CRT measurements during patient management are resource-intensive in terms of medical time and may raise issues related to healthcare staff availability.\n\nThe perfusion index (PI) is a marker of tissue perfusion derived from a pulse oximetry sensor. This monitoring device is routinely used in all critically ill patients. It is placed on the finger and worn continuously, including during patient transport.\n\nBecause PI measurement is automatic and continuous, establishing its correlation with CRT could allow for more precise tissue perfusion monitoring while reducing the time burden associated with bedside assessments in critically ill patients.",[25,26,27,28],"Shock State","Hemodynamics Instability","Microcirculation","Monitoring",[30,31,27,32],"Capillary refill time","Perfusion index","Intensive care","RECRUITING","2026-04-30",{"date":36,"type":37},"2026-05-01","ACTUAL",{"date":39,"type":37},"2026-04-29",{"date":41,"type":21},"2027-05-29",{"name":43,"class":44},"Hospices Civils de Lyon","OTHER",{"id":46,"slug":47,"hasResults":11,"nctId":48,"briefTitle":49,"officialTitle":49,"acronym":50,"eligibilityCriteria":51,"healthyVolunteers":11,"sex":17,"minAge":52,"maxAge":53,"enrollmentInfo":54,"targetDuration":56,"studyType":22,"phases":4,"briefSummary":57,"conditions":58,"keywords":61,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":71,"lastUpdatePostDateStruct":72,"startDateStruct":74,"completionDateStruct":76,"leadSponsor":78,"locationsCount":80},"100633122","fluid-responsiveness-assessment-simplified-by-electric-cardiometry-in-children-100633122","NCT07522580","Fluid-responsiveness Assessment Simplified by Electric Cardiometry in Children","FAST","Inclusion Criteria:\n\n* Age less than or equal to 8 years old\n* Hospitalization in a pediatric intensive care unit\n* Prescription by the attending physician of a fluid expansion of 10ml\u002Fkg\n* Use of a non-invasive cardiac output monitoring device (electrical cardiometry) as part of routine care\n\nExclusion Criteria:\n\n* Patient less than 37 weeks' corrected gestational age\n* Hemodynamic instability making the delay necessary for any test dangerous\n* Supine position contraindicated or deleterious\n* Impairment of echocardiographic acoustic window or restless patient making ultrasonography impossible\n* Opposition to participate expressed by the patient or by a parent or legal guardian\n* Intra-abdominal hypertension, painful abdominal palpation or abdominal surgery in the last 15 days","0 Days","8 Years",{"count":55,"type":21},42,"28 Days","In this study of diagnostic accuracy, the investigators aim to validate a faster, simpler, and noninvasive test of fluid-responsiveness in critically ill children. This test is based on an assessment of the hemodynamic effects of a standardized abdominal compression, using electrical cardiometry. This would help physicians to identify more easily which patient could benefit from a volume expansion, thus avoiding a potentially useless or even dangerous fluid expansion that could lead to fluid overload. To this end, the diagnostic accuracy of electrical cardiometry-based stroke volume (SV) variation induced by a standardized abdominal compression to predict fluid responsiveness (define as a 15% increase in echocardiographically measured SV after volume expansion) will be measured.",[59,25,60],"Circulatory Failure","Fluid Therapy",[62,63,64,65,66,67,68,69,70],"Circulatory failure","Critical Care","Echocardiography","Electrical Cardiometry","Fluid therapy","Fluid responsiveness","Goal-directed fluid management","pediatrics","volume expansion","2026-04-03",{"date":73,"type":37},"2026-04-13",{"date":75,"type":37},"2025-07-22",{"date":77,"type":21},"2027-08-19",{"name":79,"class":44},"University Hospital, Bordeaux",4]