[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"sickle-cell-anemia-hbss\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:sickle-cell-anemia-hbss":30},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,47],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":15,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":31,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":35,"lastUpdatePostDateStruct":36,"startDateStruct":39,"completionDateStruct":41,"leadSponsor":43,"locationsCount":46},"100634521","development-of-a-provider-focused-intervention-to-improve-health-outcomes-in-pediatric-sickle-cell-disease-100634521",false,"NCT07540767","Development of a Provider-Focused Intervention to Improve Health Outcomes in Pediatric Sickle Cell Disease","Inclusion Criteria:\n\n* Licensed health care provider (HCP) who provides care to youth with SCD\n* HCP employed by Connecticut Children's, Yale New Haven Children's Hospital, or Children's Hospital of Philadelphia and primary work area is Hematology\u002FOncology\n\nExclusion Criteria:\n\n* HCP who does not provide care to youth with SCD\n* HCP is a medical trainee, not including fellows\n* HCP not employed by CT Children's, Yale New Haven Children's Hospital, or Children's Hospital of Philadelphia\n* Not fluent in English",true,"ALL","18 Years",{"count":19,"type":20},30,"ESTIMATED","INTERVENTIONAL",[23],"NA","The goal of this interventional study is to learn about the impact of an intervention for health care providers that teaches individuation and perspective-taking (IPT) skills to enhance patient-centered communication in pediatric sickle cell disease (SCD). The main question it aims to answer is:\n\nDoes an intervention that teaches individuation and perspective-taking (IPT) skills to pediatric sickle cell disease (SCD) health care providers (HCPs) enhance patient-centered communication?\n\nResearchers will compare the IPT intervention to a control group who will receive education about SCD pain management to see if the IPT intervention improves patient-centered communication.\n\nParticipants will complete baseline surveys and then be randomly assigned into the intervention or control group. After completing their assigned session (IPT training or education), they will be asked to complete the same surveys as completed at baseline.",[26,27,28,29,30],"Sickle Cell Disease","Sickle Cell Anemia in Children","Sickle Cell Disease (SCD)","Sickle Cell","Sickle Cell Anemia (HbSS)",[32,33],"sickle cell","pediatrics","NOT_YET_RECRUITING","2026-04-24",{"date":37,"type":38},"2026-04-29","ACTUAL",{"date":40,"type":20},"2027-09-01",{"date":42,"type":20},"2030-06-30",{"name":44,"class":45},"Connecticut Children's Medical Center","OTHER",1,{"id":48,"slug":49,"hasResults":11,"nctId":50,"briefTitle":51,"officialTitle":51,"acronym":52,"eligibilityCriteria":53,"healthyVolunteers":11,"sex":16,"minAge":54,"maxAge":4,"enrollmentInfo":55,"targetDuration":4,"studyType":21,"phases":57,"briefSummary":59,"conditions":60,"keywords":62,"overallStatus":66,"whyStopped":4,"lastUpdateSubmitDate":67,"lastUpdatePostDateStruct":68,"startDateStruct":70,"completionDateStruct":72,"leadSponsor":74,"locationsCount":46},"100606572","phase-4-effectiveness-of-nontraditional-hydroxyurea-algorithms-novel-and-clinical-evaluations-enhance-100606572","NCT07177300","Effectiveness of Nontraditional Hydroxyurea Algorithms: Novel and Clinical Evaluations (ENHANCE)","ENHANCE","Inclusion Criteria:\n\n* Diagnosis of sickle cell anemia (HbSS) or sickle-β0-thalassemia (HbSβ0)\n* Age 6 months at the time of enrollment\n* Clinical decision by patient, family, and healthcare provider to initiate hydroxyurea therapy\n\nExclusion Criteria:\n\n* Current treatment with regularly scheduled blood transfusions\n* Sickle-hemoglobin C disease (HbSC), sickle-β+-thalassemia (HbSβ+)","6 Months",{"count":56,"type":20},50,[58],"PHASE4","The main reason for this research study is to learn more about hydroxyurea and the treatment of sickle cell anemia (SCA). Hydroxyurea is a medication that has been studied for many years and has been shown to provide benefits for people with SCA.\n\nIn this research study, the investigators hope to learn more about how to improve the dosing and monitoring of hydroxyurea and learn more about the long-term effects of hydroxyurea over time. Hydroxyurea is usually dosed based only on your weight. Our study will use a new way to select a starting dose that is based on how each patient absorbs hydroxyurea.",[30,61],"Sickle-β0-thalassemia (HbSβ0)",[63,64,32,65],"sickle cell anemia","SCD","hydroxyurea","RECRUITING","2025-09-09",{"date":69,"type":38},"2025-09-16",{"date":71,"type":38},"2024-12-19",{"date":73,"type":20},"2028-12",{"name":75,"class":45},"Children's Hospital Medical Center, Cincinnati"]