[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"sickle-cells-disease\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:sickle-cells-disease":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":26,"conditions":27,"keywords":29,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":32,"lastUpdatePostDateStruct":33,"startDateStruct":36,"completionDateStruct":38,"leadSponsor":40,"locationsCount":5},"100374548","phase-1-rh-genotype-matched-rbc-transfusions-100374548",false,"NCT04156893","RH Genotype Matched RBC Transfusions","RH Genotype Matched Red Cell Transfusions for Patients With Sickle Cell Disease","RBC","Inclusion Criteria:\n\n* Subjects age \\>6 months\n* Diagnosis of SCD, all genotypes\n* Require a period of chronic red cell transfusion therapy\n* Subject\u002Fparental\u002Fguardian permission (informed consent) and if appropriate, child assent\n\nExclusion Criteria:\n\n* Rare RH genotype that would preclude identification of sufficient RBC units\n* Antigen negative requirements due to alloimmunization that would preclude identification of sufficient RBC units\n* Alloimmunized to D antigen\n* Rh alloimmunized patients for whom providing RH genotype matched blood would expose the patient to an antigen that would not be consistent with standard of care and blood bank protocols\n* Parents\u002Fguardians or subjects who, in the opinion of the Investigator, may be non-compliant with study schedules or procedures","ALL","6 Months",{"count":20,"type":21},35,"ESTIMATED","INTERVENTIONAL",[24,25],"PHASE1","PHASE2","To determine the feasibility and efficacy of matching donor red cells by RH genotype for a cohort of chronically transfused patients with SCD.",[28],"Sickle Cells Disease",[30],"Chronic Transfusion","RECRUITING","2026-04-24",{"date":34,"type":35},"2026-04-27","ACTUAL",{"date":37,"type":35},"2020-01-30",{"date":39,"type":21},"2029-10",{"name":41,"class":42},"Children's Hospital of Philadelphia","OTHER"]