[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"sinus-lifting\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:sinus-lifting":26},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,4,0,[8,47,71,97],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":29,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":36,"lastUpdatePostDateStruct":37,"startDateStruct":40,"completionDateStruct":42,"leadSponsor":44,"locationsCount":4},"100627156","comparative-evaluation-of-xenograft-alone-and-sticky-bone-in-sinus-lift-with-concurrent-implant-placement-100627156",false,"NCT07444970","Comparative Evaluation of Xenograft Alone and Sticky Bone in Sinus Lift With Concurrent Implant Placement","Comparative Evaluation of Xenograft Alone and Sticky Bone in Sinus Lift With Concurrent Implant Placement: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Adults aged 18 years and older.\n* Patients presenting with residual bone height of less than 5 millimeters in the posterior maxilla requiring sinus floor elevation for dental implant placement.\n* Good oral hygiene status with absence of active periodontal disease.\n* Medically fit patients with no systemic conditions contraindicating oral surgical procedures.\n* Non-smokers.\n* Absence of acute or chronic maxillary sinusitis.\n\nExclusion Criteria:\n\n* Presence of uncontrolled systemic diseases (e.g., uncontrolled diabetes mellitus or severe cardiovascular diseases).\n* Immunocompromised patients.\n* History of radiation therapy to the head and neck region.\n* History of sinus surgery or sinus pathology that may interfere with sinus floor elevation procedures.\n* Presence of active infection or inflammation at the intended surgical site.\n* Use of medications known to affect bone metabolism or healing, such as bisphosphonates or long-term corticosteroid therapy.","ALL","18 Years",{"count":19,"type":20},18,"ESTIMATED","INTERVENTIONAL",[23],"NA","Introduction \\& Background:\n\nModern dental implantology offers solutions for patients with edentulism in the maxillary arch, where sinus pneumatization and alveolar ridge atrophy are common conditions. This often requires sinus floor elevation and bone grafting prior to implant placement. Techniques such as the lateral window approach and osteotome-mediated sinus floor elevation aim to achieve sufficient vertical bone height for successful implant placement.\n\nAutogenous bone grafts have long been considered the gold standard; however, their use is associated with limitations including donor site morbidity and graft volume loss, which has encouraged the exploration of alternative grafting materials. Sticky bone is a term used in oral surgery and implantology to describe a cohesive, moldable, and adhesive bone graft material prepared by combining particulate bone graft material (xenograft) with biological additives such as Platelet-Rich Plasma (PRP) or Platelet-Rich Fibrin (PRF).\n\nPlatelet-Rich Fibrin (PRF), which is used in the present study, is an autologous leukocyte and platelet-rich fibrin matrix containing cytokines, platelets, and stem cells. PRF acts as a biodegradable scaffold that promotes microvascularization and guides epithelial cell migration. In addition, PRF may serve as a carrier for regenerative cells and allows sustained release of growth factors over a period ranging from one to four weeks, thereby enhancing the wound healing environment.\n\nObjectives:\n\nThe study aims to assess the clinical efficacy of sticky bone as a bone graft material in sinus lift procedures compared with conventional xenograft materials.\n\nMethods:\n\nA randomized clinical trial will be conducted comparing two groups: one receiving sticky bone with simultaneous implant placement and another receiving xenograft with implant placement. Preoperative assessment will include Cone Beam Computed Tomography (CBCT) imaging, followed by postoperative monitoring to evaluate bone height and implant stability.\n\nStudy Design:\n\nPatients fulfilling the inclusion and exclusion criteria will be recruited from the dental clinic. Written informed consent will be obtained from all participants after explanation of study procedures, potential risks, and expected benefits. Eligible patients will be randomly allocated into two equal groups using a computer-generated randomization program: Group 1 (Sticky Bone group) and Group 2 (Xenograft group).\n\nStatistical Analysis:\n\nSample size calculation was performed using G\\*Power software version 3.1.9.7. The statistical test family selected was the t-test. Based on data from a previous study, a total of 16 participants were required to achieve a study power of 80% with a significance level (alpha) of 0.05. To compensate for potential dropouts, the total sample size was increased to 18 participants (9 patients per group).",[26,27,28],"Sinus Lifting","Dental Implant","Sticky Bone",[30,31,32,33,34],"Dental implants","sticky bone","bone graft","sinus lift","PRF","NOT_YET_RECRUITING","2026-05-21",{"date":38,"type":39},"2026-05-26","ACTUAL",{"date":41,"type":20},"2026-06-01",{"date":43,"type":20},"2027-04-01",{"name":45,"class":46},"Fayoum University","OTHER",{"id":48,"slug":49,"hasResults":11,"nctId":50,"briefTitle":51,"officialTitle":52,"acronym":53,"eligibilityCriteria":54,"healthyVolunteers":11,"sex":16,"minAge":4,"maxAge":4,"enrollmentInfo":55,"targetDuration":4,"studyType":57,"phases":4,"briefSummary":58,"conditions":59,"keywords":4,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":61,"lastUpdatePostDateStruct":62,"startDateStruct":64,"completionDateStruct":66,"leadSponsor":68,"locationsCount":70},"100632309","outcomes-of-different-bone-graft-combinations-for-maxillary-sinus-augmentation-procedure-100632309","NCT07512011","Outcomes of Different Bone Graft Combinations for Maxillary Sinus Augmentation Procedure","Maxillary Sinus Augmentation Through Lateral Window Technique: Outcomes of Different Bone Graft Combinations (MSA-BGC STUDY)","MSA-BGC","Inclusion Criteria:\n\n* Indication of bilateral sinus augmentation through lateral window technique to prepare maxillary right and left posterior edentulous sites for a single or multiple unit implant supported restorations.\n* Systemically healthy with controlled conditions\n* Periodontally healthy\u002Fcontrolled dentition\n* No known chronic and\u002For seasonal sinusitis\n* No previous ear, nose, throat, and sinus surgeries\n* Non-smokers\n* Willing to be treated with allograft, xenograft and\u002For synthetic bone graft materials\n\nExclusion Criteria:\n\n* 1\\. Indication of sinus augmentation through indirect techniques (≥5 mm initial alveolar ridge height from crest to maxillary sinus floor)\n* Implant placement surgery planned somewhere else\n* Implant placement planned at the time of sinus augmentation\n* Cases requiring major alveolar ridge augmentation concurrent with sinus augmentation\n* Cases requiring the use of a partial denture with buccal flange extension during the post-operative period\n* History of previously failed implant and\u002Fsinus augmentation procedures\n* History of tumors and\u002For radiation and\u002For chemotherapy\n* Uncontrolled systemic health problems and ENT\u002Fsinus concerns\n* Uncontrolled periodontal\u002Fdental problems\n* Intake of medications affecting wound or bone healing (e.g., corticosteroids, immunosuppressants, etc.)\n* Alcohol or drug abuse\n* Active smokers (patient should be a non-smoker for at least 1 year prior to sinus augmentation procedure)\n* Unable\u002Funwilling to follow post-operative instructions, rejecting to be treated with allograft, xenograft and\u002For synthetic bone graft materials\n* Unable\u002Funwilling to attend scheduled study visits\n* Participation in another clinical trial within 3 months prior to planned study entry",{"count":56,"type":20},10,"OBSERVATIONAL","This study investigates the outcomes of a surgical procedure that is performed to increase bone support at a future implant site on the upper back jaw area. This procedure requires placing bone graft material and\u002For substitutes into the maxillary sinus. The average healing time for the graft is about 6 months. Then, the site will be ready for dental implant. The study will compare healing outcomes of two types of bone graft mixtures used on the same patient (right and left upper jaw regions). The outcomes will be evaluated through clinical examination but also by studying the quality of the tissue through tissue biopsies obtained from grafted sites.",[60,26],"Bone Grafting","2026-04-03",{"date":63,"type":39},"2026-04-06",{"date":65,"type":20},"2026-06",{"date":67,"type":20},"2027-06",{"name":69,"class":46},"Ohio State University",1,{"id":72,"slug":73,"hasResults":11,"nctId":74,"briefTitle":75,"officialTitle":76,"acronym":4,"eligibilityCriteria":77,"healthyVolunteers":11,"sex":16,"minAge":78,"maxAge":79,"enrollmentInfo":80,"targetDuration":4,"studyType":21,"phases":82,"briefSummary":83,"conditions":84,"keywords":85,"overallStatus":87,"whyStopped":4,"lastUpdateSubmitDate":88,"lastUpdatePostDateStruct":89,"startDateStruct":91,"completionDateStruct":93,"leadSponsor":95,"locationsCount":70},"100604541","erythropoietin---albumin-platelet-rich-fibrin-in-transcrestal-sinus-lifting-with-simultaneous-implant-placement-100604541","NCT07150858","Erythropoietin - Albumin Platelet-rich Fibrin in Transcrestal Sinus Lifting With Simultaneous Implant Placement","Comparison Between Erythropoietin-enhanced Albumin Platelet-rich Fibrin and Albumin Platelet-rich Fibrin in Transcrestal Sinus Lifting With Simultaneous Implant Placement","Inclusion Criteria:\n\n* Residual bone height not less than 5 mm measured from crestal bone to sinus floor.\n* Both genders.\n* Good oral hygiene\n* No previous surgery or radiation treatment on the maxillary sinus\n\nExclusion Criteria:\n\n* Recent radiation therapy in maxilla.\n* Uncontrolled systemic diseases such as diabetes mellitus.\n* Heavy smoker (those who smoke ≥ 25 cigarettes a day).\n* Alcohol abuse.\n* Patient on anticoagulant drug\n* Severe allergic rhinitis.\n* Tumor or large cyst in the maxillary sinus.\n* Oroantral fistula.\n* Presence of acute or chronic sinus pathoses or sinus membrane perforation.(","20 Years","60 Years",{"count":81,"type":20},20,[23],"Background: Dental implant therapy in the posterior maxilla may be difficult owing to limited bone height after dental extraction with sinus pneumatization. Several approaches for sinus floor elevation have been documented, and hence trans crestal sinus lifting with albumin platelet rich plasma.\n\nAim of the study: To compare between erythropoietin and albumin platelet rich fibrin transcrestal sinus lifting versus albumin platelet rich fibrin transcrestal sinus lifting using piezoelectric device in patients with atrophic maxilla.\n\nMethods: This study will be carried out as a randomized",[26],[86],"Transcrestal sinus lifting, erythropoitein, albumin PRF, Peizo electric device, Dental implants, CBCT.","RECRUITING","2025-08-27",{"date":90,"type":39},"2025-09-02",{"date":92,"type":39},"2025-05-25",{"date":94,"type":20},"2026-07-25",{"name":96,"class":46},"Alexandria University",{"id":98,"slug":99,"hasResults":11,"nctId":100,"briefTitle":101,"officialTitle":101,"acronym":4,"eligibilityCriteria":102,"healthyVolunteers":103,"sex":16,"minAge":4,"maxAge":4,"enrollmentInfo":104,"targetDuration":4,"studyType":21,"phases":106,"briefSummary":107,"conditions":108,"keywords":4,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":109,"lastUpdatePostDateStruct":110,"startDateStruct":112,"completionDateStruct":114,"leadSponsor":116,"locationsCount":4},"100596246","evaluation-of-customized-zirconia-membrane-in-direct-sinus-lifting-with-simultaneous-implant-placement-randomized-control-trial-100596246","NCT07042958","Evaluation of Customized Zirconia Membrane in Direct Sinus Lifting With Simultaneous Implant Placement: (Randomized Control Trial)","Patient will be selected according to certain inclusion and exclusion criteria:\n\n1\\. Inclusion criteria Patient with Atrophic posterior maxilla and remaining bone height less than 6 mm.\n\nI. ASA physical status I and II. II. Patient with healthy maxillary sinus free from any pathology. III. The edentulous ridges are covered with optimal thickness of Mucoperiosteum with no signs of inflammation, ulceration or scar tissue.\n\nIV. Occlusion showed sufficient inter arch space for future prosthesis.\n\nExclusion Criteria:\n\nGeneral contraindications to implant surgery. I. Untreated gingivitis, periodontitis. II. Patient with maxillary sinusitis. III. Smoker patient. IV. Patient with parafunctional habits. V. Subjected to irradiation in the head and neck area less than 1 year before implantation.\n\nVI. Pregnant or nursing.",true,{"count":105,"type":20},24,[23],"Modern dental implantology offers solutions for patients with edentulism in the maxillary arch, where sinus pneumatization and alveolar ridge atrophy are common. This requires sinus floor elevation and bone grafting for implant placement. Techniques like the lateral window approach and osteotome-mediated sinus floor elevation aim to achieve the necessary vertical bone height for implants. Autogenous bone grafts have been the gold standard but have limitations like donor site morbidity and graft volume loss, leading to the exploration of alternatives. Membranes, such as resorbable collagen or titanium-reinforced materials, are commonly used in these procedures but have limitations related to customization, cost, and failure rates.Recent studies have suggested that placing implants directly into the sinus without grafting material can stimulate bone formation, leveraging blood clots to activate bone-forming cells. Zirconia, a ceramic material known for its bioinertness and mechanical strength, is being explored for its potential in sinus lift procedures. Customized 3D zirconia membranes may offer a solution to enhance bone formation and soft tissue integration during sinus lifts.This study aims to evaluate the effect of using customized zirconia membranes in sinus lift procedures with simultaneous implant placement, comparing bone height outcomes with conventional sinus lifts without membranes",[26],"2025-06-20",{"date":111,"type":39},"2025-06-29",{"date":113,"type":20},"2025-07-01",{"date":115,"type":20},"2026-07-01",{"name":45,"class":46}]