[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"skeletal-malocclusion\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:skeletal-malocclusion":32},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,54,84],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":4,"briefSummary":24,"conditions":25,"keywords":36,"overallStatus":41,"whyStopped":4,"lastUpdateSubmitDate":42,"lastUpdatePostDateStruct":43,"startDateStruct":46,"completionDateStruct":48,"leadSponsor":50,"locationsCount":53},"100371514","orthognathic-speech-pathology-phonetic-contrasts-of-patients-with-dental-discrepancies-pre--and-post-treatment-analyses-100371514",false,"NCT04117360","Orthognathic Speech Pathology: Phonetic Contrasts of Patients With Dental Discrepancies Pre- and Post-Treatment Analyses","Orthognathic Speech Pathology: Phonetic Contrasts of Patients With Dentofacial Discrepancies With Pre- and Post-Treatment Analyses","OSP","Inclusion Criteria:\n\n* Jaw surgery patient at UNC with a skeletal open bite, underbite or overjet greater than 5mm.\n* Age 15-40 years\n\nExclusion Criteria:\n\n* Hearing loss\n* Learned English as a second language\n* Significant regional accent, as characterized by a speech pathologist\n* Developmental delay, performing several grade levels below age bracket\n* history of craniofacial disorder\n* genetic syndrome associated with known craniofacial presentation\n* history of craniofacial trauma\n* history of prior craniofacial surgery (excluding extractions and dental procedures)\n* Jaw surgery without fixed orthodontic appliances","ALL","15 Years","40 Years",{"count":21,"type":22},180,"ESTIMATED","OBSERVATIONAL","The investigators are studying how speech is effected by jaw and tooth position in jaw surgery patients. Eighty percent of our jaw surgery patients have speech pathologies, compared to five percent of the general population, but speech pathologists do not understand why. The investigators hypothesize that open bites and underbites prevent most patients from being able to pronounce words normally and surgical correction will lead to improvement in speech. Patients will be audio recorded speaking and patients' tongue gestures ultrasound recorded before and after their jaw surgeries to observe what changes occur in their speech and tongue movements.",[26,27,28,29,30,31,32,33,34,35],"Dentofacial Abnormalities","Dentofacial Deformities","Dentofacial Anomalies, Including Malocclusion","Malocclusion","Malocclusion in Children","Dentofacial Disharmony","Skeletal Malocclusion","Skeletal Malformation","Speech Sound Disorder","Speech Disorders",[31,37,34,38,39,40],"Skeletal malocclusion","Spectral Moment Analysis","Tongue Ultrasound","Orthognathic Surgery","RECRUITING","2026-06-10",{"date":44,"type":45},"2026-06-12","ACTUAL",{"date":47,"type":45},"2019-09-11",{"date":49,"type":22},"2028-03",{"name":51,"class":52},"University of North Carolina, Chapel Hill","OTHER",1,{"id":55,"slug":56,"hasResults":11,"nctId":57,"briefTitle":58,"officialTitle":59,"acronym":4,"eligibilityCriteria":60,"healthyVolunteers":11,"sex":17,"minAge":61,"maxAge":62,"enrollmentInfo":63,"targetDuration":4,"studyType":65,"phases":66,"briefSummary":68,"conditions":69,"keywords":70,"overallStatus":74,"whyStopped":4,"lastUpdateSubmitDate":75,"lastUpdatePostDateStruct":76,"startDateStruct":78,"completionDateStruct":80,"leadSponsor":82,"locationsCount":53},"100564596","comparison-between-aesthetic-functional-appliances-and-twin-block-in-correction-of-skeletal-class-ii-100564596","NCT06631235","Comparison Between Aesthetic Functional Appliances and Twin Block in Correction of Skeletal Class II","Comparison Between Aesthetic Functional Appliances and Twin Block in Correction of Skeletal Class II: Randomized Controlled Study","Inclusion Criteria:\n\n* Skeletal Class II pattern with ANB angle exceeding 6° and Wits appraisal of 2 mm or more.\n* Mandibular deficiency (SNB angle less than 77°).\n* Growing patients.\n* No prior orthodontic intervention.\n* The vertical skeletal classification shows a horizontal or neutral growth pattern.\n* Overjet ≥ 8mm.\n\nExclusion Criteria:\n\n* Developmental abnormalities with atypical or irregular patterns of growth and maturation.\n* Any indications or manifestations, as well as any prior medical records, of Tempro-Mandibular Joint (TMJ) disorders, such as the presence of clicking, pain, limitations, or deviations.","8 Years","12 Years",{"count":64,"type":22},42,"INTERVENTIONAL",[67],"NA","The goal of this is to evaluate the skeletal, dental and soft tissue effects between aesthetic functional appliance and Twin block appliance in treatment of skeletal class II in ( growing male\u002Ffemale patients)",[32],[71,72,73],"classII","mandibular advancement","twin block","NOT_YET_RECRUITING","2024-10-18",{"date":77,"type":45},"2024-10-21",{"date":79,"type":22},"2024-11-01",{"date":81,"type":22},"2026-11-01",{"name":83,"class":52},"Mansoura University",{"id":85,"slug":86,"hasResults":11,"nctId":87,"briefTitle":88,"officialTitle":89,"acronym":4,"eligibilityCriteria":90,"healthyVolunteers":11,"sex":17,"minAge":91,"maxAge":92,"enrollmentInfo":93,"targetDuration":4,"studyType":23,"phases":4,"briefSummary":95,"conditions":96,"keywords":4,"overallStatus":74,"whyStopped":4,"lastUpdateSubmitDate":97,"lastUpdatePostDateStruct":98,"startDateStruct":100,"completionDateStruct":101,"leadSponsor":103,"locationsCount":53},"100553383","electromiographic-evaluation-and-skeletal-parameters-of-patients-requiring-orthodontic-treatment-100553383","NCT06485375","Electromiographic Evaluation and Skeletal Parameters of Patients Requiring Orthodontic Treatment","Electromiographic Evaluation and Skeletal Parameters of Patients Requiring Orthodontic Treatment: a Prospective Cross-sectional Study","Inclusion Criteria:\n\n* Patients needing an orthopaedic and\u002For orthodontic treatment\n* Deciduous, mixed, or permanent dentition\n\nExclusion Criteria:\n\n* Systemic diseases or congenital anomalies affecting craniofacial growth or development\n* Signs or symptoms of temporomandibular disorder (TMD)\n* Dental Pain\n* Past maxillofacial surgery","6 Years","25 Years",{"count":94,"type":22},50,"The relationship between form and function within the craniofacial complex has been investigated by several Authors. However, there is still controversy regarding the different electromyographic activation patterns of the elevator muscles of the jaw. One particularly contentious area of enquiry is whether it is facial morphology that determines the strength of muscle activation, or whether a strong musculature can influence skeletal growth processes.\n\nIn light of the aforementioned considerations, the objective of the current clinical observational study was to investigate the potential correlation between the electromyographic activity of selected masticatory muscles (masseter, anterior temporalis and suprahyoid) and the craniofacial morphology of subjects under examination, with a particular focus on elucidating the mechanical advantage derived from different sagittal relationships between the maxillae. The electromyographic evaluation is carried out before the beginning of the orthodontic treatment (T0).",[32],"2024-06-28",{"date":99,"type":45},"2024-07-03",{"date":99,"type":22},{"date":102,"type":22},"2024-09-25",{"name":104,"class":52},"University of Pavia"]